Download or read book OMERACT IV written by and published by . This book was released on 1999 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Journal of Rheumatology written by and published by . This book was released on 2006 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Kelley s Textbook of Rheumatology written by Gary S. Firestein and published by Elsevier Health Sciences. This book was released on 2013 with total page 2345 pages. Available in PDF, EPUB and Kindle. Book excerpt: Helps you to better understand scientific underpinnings of rheumatic diseases, so that you can better manage your patients.
Download or read book Clinical Trials in Rheumatoid Arthritis and Osteoarthritis written by David M. Reid and published by Springer Science & Business Media. This book was released on 2008-03-20 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed to be a practical handbook on clinical trial management in these key therapeutic areas, 'Clinical Trials in Rheumatoid Arthritis and Osteoarthritis' is aimed at principal investigators pharmaceutical physicians and other pharmaceutical staff involved in the design, conduct and monitoring of these increasingly complex diseases. In the last several years a new classes of biologic agents have emerged and changed the treatment paradigm for patients, not only with classically defined rheumatoid arthritis, but also with other related diseases such as ankylosing spondylitis and psoriatic arthritis. Furthermore, osteoarthritis is a major disease state that is often treated by the rheumatologist, but is one where patient management programs are currently limited with a need for new therapeutic approaches. In both inflammatory and non-inflammatory arthritic conditions, clinical trials have become both large and complex due to the nature of the diseases, with ever-challenging new surrogate end-points being employed. Topics covered in this title will therefore include study design, clinical endpoints, technical issues, data collection, use of centralized medical image reading facilities and biochemical marker laboratories, as well as data analysis and future therapies. This book takes the user through the process step-by-step from start to finish, also providing a background on the regulatory guidelines, ethical implications, endpoints, and current therapies.
Download or read book Small Clinical Trials written by Institute of Medicine and published by National Academies Press. This book was released on 2001-02-01 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.
Download or read book Evidence Based Rheumatology written by Peter Tugwell and published by John Wiley & Sons. This book was released on 2009-07-10 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Compiled by Cochrane collaborators and members of OMERACT (Outcome Measures in Rheumatology), Evidence-based Rheumatology is an essential resource for evidence-based medicine as applied to the musculoskeletal disorders. The introductory section covers the principles of evidence-based medicine in rheumatology, followed by clinical chapters covering all the major disorders. Each chapter includes non-drug therapy, drug therapy, and consumer evidence-based summaries. Evidence-Based Series: Evidence-based Rheumatology, part of the acclaimed series BMJ Evidence-based medicine textbooks that have revolutionised clinical medicine literature, comes with a fully searchable CD-ROM of the whole text. The text is kept up to date online at www.evidbasedrheum.com Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.
Download or read book New Insights into Rheumatoid Arthritis An Issue of Rheumatic Disease Clinics written by David A. Fox and published by Elsevier Health Sciences. This book was released on 2010-06-29 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are numerous monographs devoted to rheumatoid arthritis. What sets this issue apart is that it keeps an eye to the future. Topics explored include measurement of RA disease activity today and in the future; epidemiology of RA – implications for prevention and risk assessment; genes that predispose to RA – relevance to current and future therapeutic strategies; multiple kinases – assessment of the best targets in treating RA; assessment, prevention and treatment of cardiovascular morbidity in RA; mechanistic insights and approaches to prevention of bone damage in RA; cell-cell interactions in RA synovium as potential new targets for treatment; alternative strategies for modulating the function of B lymphocytes in RA; innate immunity in RA; ascertainment and management of preclinical RA.
Download or read book Patient Reported Outcomes in Rheumatic Diseases An Issue of Rheumatic Disease Clinics of North America E Book written by Jennifer L. Barton and published by Elsevier Health Sciences. This book was released on 2016-05-27 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue is devoted to patient reported outcomes and their impact in the study of rheumatic diseases and the authors will also discuss PROs and vulnerable populations with rheumatic disease; technology, electronic health records and PROs: past, present and future; the promise of PROMIS – a uniform approach to PROs across rheumatic diseases, quality measures and PROs and how they relate and the importance of PROs in delivering quality care in the rheumatic diseases, and many more exciting articles.
Download or read book Outcome Measures and Metrics in Systemic Lupus Erythematosus written by Zahi Touma and published by Springer Nature. This book was released on 2021-07-22 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that manifests with a myriad of clinical and laboratory features. The assessment of SLE is comprehensive and includes different core set domains; disease activity, damage, health-related quality of life, adverse events and economic impact. This comprehensive book is focused on the instruments and outcome measures utilized in the assessment of SLE. It targets different audiences including physicians, scientists/researchers and different health professionals interested in learning about the art of measurement in SLE. The book highlights the importance of measurement in the assessment of SLE in a clinical settings, research and clinical trials. Each of the chapters provide a systematic approach to the instruments utilized in the assessment of a specific construct in SLE (e.g., disease activity, fatigue, etc.) and incorporate a comprehensive coverage of disease specific and disease generic measures. It also discusses different patient-reported outcomes that are crucial to reflect patient perceptions of their health condition and cover constructs such as fatigue, pain, anxiety and depression, cognition, frailty, and many others.
Download or read book Oxford Textbook of Axial Spondyloarthritis written by Robert Inman and published by Oxford University Press. This book was released on 2017-06-30 with total page 828 pages. Available in PDF, EPUB and Kindle. Book excerpt: Axial Spondyloarthritis is a timely addition to the Oxford Textbooks in Rheumatology series, providing a comprehensive reference to this rapidly evolving field. The conceptual framework of the disease has now evolved beyond ankylosing spondylitis to encompass a broader concept of axial inflammation. Earlier recognition has opened the door to earlier intervention, and the understanding of the biologic basis of axial SpA has seen significant advances in recent years. The first textbook to cover axial spondyloarthritis in this level of detail from a global perspective, this volume offers a practical and complete resource compiled by a multidisciplinary and multinational team of experts. Beginning with a historical perspective on the disease, the textbook provides a comprehensive background in the epidemiology, diagnosis, and classification of axial spondyloarthritis. Immune mechanisms and genetics are covered, along with imaging and a detailed section on the range of treatments options currently available. A section on extra-articular manifestations provides a comprehensive knowledge base for the clinician treating patients with spondyloarthritis, and chapters on the economics of the disease, physical functioning, and patient registries complete the broad coverage of the topic. Practical, easy to use, yet detailed with respect to pathophysiology, diagnostics, and management, this textbook provides a comprehensive reference for rheumatologists, general practitioners, internists, and paediatricians managing patients with axial spondyloarthritis.
Download or read book Kelley s Textbook of Rheumatology written by Shaun Ruddy and published by Saunders. This book was released on 2001 with total page 1016 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely updated to reflect the latest advances in the field, the 6th Edition of this masterwork encompasses all of today's best knowledge about arthritis and musculoskeletal diseases. A "who's who" of world authorities document the explosion of new information and new developments that have occurred in rheumatology. Coverage progresses from normal joint biology and recent discoveries about immune and inflammatory responses...through diagnosis and pharmacology...to the evaluation and management of all of the individual rheumatologic diseases seen in practice. 48 of the 115 chapters have been completely rewritten by totally new authors. Others have been extensively revised to present the most state-of-the-art information. An entirely new section thoroughly explores Vasculitic Syndromes. A new section on Special Issues features expanded discussions of alternative treatments and chronic pain management. The section onReconstructive Surgery now features the authorship of Dr. Clement B. Sledge. Every illustration has been redrawn by a single, outstanding medical illustrator to provide a comprehensible account of all surgical options. The imaging chapter by Dr. Barbara Weissman provides an encyclopedic collection of images on joint pathology.
Download or read book Tidy s Physiotherapy E Book written by Stuart Porter and published by Elsevier Health Sciences. This book was released on 2008-04-01 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: The essential book to refer to, whether you’re just starting out or about to go on placement or need to look up something for an assessment, the 14th edition of Tidy’s Physiotherapy is up-to-date and ready to meet the needs of today’s physiotherapy student. Chapters are written by specialists who have come from a wide range of clinical and academic backgrounds. Each chapter encourages you to problem solve and provides case studies to give the opportunity to consolidate learning and to give you confidence when you need to apply what you have learned. For the first time, a DVD ROM is included which contains sections on musculoskeletal tests, massage and exercise, and graphics which can be used for revision, presentations and even teaching. New techniques include core stability and muscle imbalance techniques - keeping the student informed of current developments • Hot topics covered, including NHS structure, the role of research and clinical governance • Case studies included to help the student think about their reading in a real-life context • New text design with redrawn and updated illustrations means the book is easier to navigate • Totally updated for today's physiotherapist High quality annotated art illustrations Case studies which provide further insights into the physiotherapists clinical reasoning Web links DVD containing videoclips and downloadable photographs Additional chapters on Care of the Ventilated Patient; Caridac and Pulmonary Rehabilitation, Management of Tissue Healing and Repair, Massage, Electrotherapy, Pain and Changing Relationships for Promoting Health Part of the Physiotherapy Essentials series - core textbooks for both students and lecturers
Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1828 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Lupus An Issue of Rheumatic Disease Clinics of North America E Book written by Zahi Touma and published by Elsevier Health Sciences. This book was released on 2021-07-06 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Rheumatic Disease Clinics, guest edited by Dr. Alfred Kim and Zahi Touma, will discuss a number of key topics surrounding Lupus. This issue is one of four selected each year by series Consulting Editor, Dr. Michael Weisman. Topics discussed in this issue include, but are not limited to: Interferons in SLE, NETosis and neutrophils in SLE, AMP update in lupus nephritis, Patient-reported outcomes, Complement, T cells in SLE, B cells in SLE, Outcome measures for SLE clinical trials, Mitochondrial physiology in SLE, Pregnancy, Lupus cohorts, Innovative trials and new opportunities in SLE, Classification and diagnosis of SLE, and Updates on SLE Treatment.
Download or read book Tidy s Physiotherapy written by Stuart B. Porter and published by Elsevier Health Sciences. This book was released on 2008 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the first time the textbook includes a DVD ROM containing sections on musculoskeletal tests, massage and exercises, as well as high resolution graphics that can be used to aid revision, student presentations and teaching purposes.
Download or read book Rheumatology E Book written by Marc C. Hochberg and published by Elsevier Health Sciences. This book was released on 2018-01-08 with total page 6453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly revised and updated, the 7th Edition of Rheumatology remains a leading text in this fast-changing field, keeping you abreast of recent advances in medications, therapies, clinical trials, and much more. Dr. Mark Hochberg and his team of expert authors and editors cover everything you need to know -- from basic scientific principles to practical clinical management strategies, all in a user-friendly, accessible manner. Provides access to quick, concise videos depicting musculoskeletal ultrasound including anisotropy, "comet tail" needle artifact, rheumatoid arthritis synovitis, acute gout, and more. Uses a consistent, logical, reader-friendly format with templated content and large-scale images for efficient visual reference. Features 14 completely new chapters covering biomedical and translational science, disease and outcome assessment, including new imaging modalities and early emerging disease, clinical therapeutics, and patient management and rehabilitation. Includes updated content on the latest diagnostic perspectives and approaches to therapy including tapering down of treatment, pulmonary hypertension and scleroderma, psoriatic arthritis, and the latest oral anticoagulants. Covers hot topics such as pathogenesis and pathophysiology of axial spondyloarthritis, DXA and measurement of bone, infectious arthritis, and more. Shares the knowledge and expertise of internationally recognized rheumatoid arthritis expert and new editor, Dr. Ellen Gravallese. Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Download or read book Ankylosing Spondylitis written by Muhammad Asim Khan and published by Oxford University Press. This book was released on 2009 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ankylosing Spondylitis (AS) and related diseases called spondyloarthropathies (SpA) are the second most common form of chronic inflammatory arthritis after Rheumatoid Arthritis (RA). Unfortunately, most patients with AS and SpA are either never diagnosed, or they are inadequately treated. The current mean delay in the diagnosis of AS ranges from 5 to 10 years, and the presenting clinical manifestations of these diseases are wide-ranging and heterogeneous, and thus a variety of health care professionals see AS and SpA patients, from primary care physicians to rheumatologists and other medical and surgical specialists. With the availability of newer, highly effective treatments and better methods of musculoskeletal imaging, such as the MRI, there is an urgent need to improve early diagnosis and reduce any inappropriate delay in obtaining effective treatment. Earlier diagnosis and treatment can mitigate the severity of the disease, and make a meaningful difference for patient care and quality of life. The proposed book is designed for specialists and generalists alike, and is intenteded to expedite accurate diagnosis and initiation of appropriate treatment in order to alleviate unnecessary suffering. Part of the new Oxford American Rheumatology Library series, this pocket-sized book provides practical, evidence-based information for clinicians to aid diagnosis, treatment, and follow-up care for patients with AS and SpA. The book provides pointers to early diagnosis, prognosis, clinical manifestations, socioeconomic aspects, and disease management. It also provides comprehensive coverage of current treatment options, including the latest biologics, as well as non-drug therapies.
