Download or read book Oligodendroglia written by William Norton and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series has addressed a constituency of scientists possessing biochemical background with the goal of providing them with specialized reviews of neu robiological interest. Since its initiation, neurochemistry and neuroscience have come of age, and the editors initiate with this volume the concept of a central theme. It is planned that each subsequent volume will also be topical. We note with sadness the passing of Dr. Henry Mahler who served as an advisory editor since the initiation of this series. He played a major role in building the bridge between biochemistry and neurochemistry and will be missed. Weare pleased to welcome two new editors, Drs. William Norton and Bruce McEwen. B. W. Agranoff M. H. Aprison vii FOREWORD Oligodendroglia constitute one of the three principal cell types of the central nervous system. These cells, together with their elaborated membranes, account for at least 25 percent of the dry mass of an adult rat brain and an even greater percentage of the central nervous system of larger animals.

Download or read book The Role of Astroglia and Oligodendroglia in CNS Development Plasticity and Disease Novel Tools and Investigative Approaches written by Enrica Boda and published by Frontiers Media SA. This book was released on 2022-05-31 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Rio Hortega s Third Contribution to the Morphological Knowledge and Functional Interpretation of the Oligodendroglia written by Jose R. Iglesias-Rozas and published by Newnes. This book was released on 2013-06-05 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pío del Rio-Hortega, one of the pioneering neuroscientists and discoverer of microglia, has been recognized as one of the most important Spanish neurohistogists of the past century. His landmark research on oligodendroglia, originally published in Spanish in 1928, has been translated into English for the first time by Dr. José R. Iglesias-Rozas and Prof. Manuel Garrosa. The book establishes definitively the concept of oligodendroglia and describes in great detail its structure, varieties, function, origin and pathology, providing a thorough review. The entire 1928 writing is presented, including the 79 excellent drawings and photographs from the original publication. To complement the original book and provide historical context, the translators have also included an introduction to the research and a biography of Pío del Rio-Hortega. This book constitutes a milestone in the history of neuroscience, biology and medicine, and it will be valuable reading for researchers and practitioners in these fields. First English translation of seminal 1928 research Contains the broad descriptions and interpretations of the normal and pathological oligodendroglia Full original text and new introductory sections

Download or read book The Biology of Oligodendrocytes written by Patricia Armati and published by Cambridge University Press. This book was released on 2010-10-21 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditionally, oligodendrocytes have been assumed to play a minor supporting role in the central nervous system and their importance has generally been overlooked. For the first time, this book provides a dedicated review of all of the major aspects of oligodendrocyte biology, including development, organization, genetics, and immunobiology. Later chapters emphasize the importance of this underestimated cell to the mammalian central nervous system by exploring the role of myelin synthesis and maintenance in neural disease and repair. Particular attention is paid to multiple sclerosis (MS), arguably the prime example of an acquired demyelinating disease, with detailed examinations of the current concepts regarding demyelination, oligodendroglial damage, and remyelination in MS lesions.

Download or read book Handbook of Neurochemistry and Molecular Neurobiology written by Abel Lajtha and published by Springer Science & Business Media. This book was released on 2008-06-06 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nervous system is highly fragile, especially during aging, illness and trauma. This book addresses a small sampling of major constituents of neural function at the cellular and molecular level that play crucial roles in development and aging.

Download or read book Neuroimmune Pharmacology written by Tsuneya Ikezu and published by Springer. This book was released on 2016-12-22 with total page 1045 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Neuroimmune Pharmacology bridges the disciplines of neuroscience, immunology and pharmacology from the molecular to clinical levels with particular thought made to engage new research directives and clinical modalities. Bringing together the foremost field authorities from around the world, Neuroimmune Pharmacology will serve as an invaluable resource for the basic and applied scientists of the current decade and beyond.

Download or read book Archives of Neurology and Psychiatry written by and published by . This book was released on 1926 with total page 842 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Myelination and Demyelination written by Jarma Palo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: A satellite symposium entitled "Myelination and Demyelination: Recent Chemical Advances" was held in Helsinki from August 29 to 31, 1977, after the Sixth International Meeting of the International Society for Neurochemistry (ISN) in Copenhagen. Myelin is a nervous tissue structure that is most suitable as a subject of biochemical investigation. It is easy to isolate in a highly purified form, is rather stable even after death, and is af fected by a variety of neurological and other diseases. Its lesions are particularly important in the study of multiple sclerosis, a disease which is relatively prevalent in Finland and has therefore been of interest to a great many Finnish scientists. The first half of this book is concerned with the biochemical composition and molecular organization of myelin, the second half with the experimental and clinical aspects of demyelination. The comments given after each of the presentations at the symposium were not recorded as such, but each author was requested to modify his or her paper accordingly. The editing and publication of this book would not have been possible without the excellent efforts and co-operation of my wife, Mrs. L.-M. Palo, acting as general secretary and later as editorial secretary of the symposium. As Organizing Committee Chairman, I would also like to thank the members of the Committee: Dr. M. Haltia, Dr. E. Kivalo, Dr. T. Kosunen, Dr. M. Panelius, and especially Dr.

Download or read book Glial Cells in Health and Disease of the CNS written by Rommy von Bernhardi and published by Springer. This book was released on 2016-10-06 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely overview covering the three major types of glial cells in the central nervous system - astrocytes, microglia, and oligodendrocytes. New findings on glia biology are overturning a century of conventional thinking about how the brain operates and are expanding our knowledge about information processing in the brain. The book will present recent research findings on the role of glial cells in both healthy function and disease. It will comprehensively cover a broad spectrum of topics while remaining compact in size.

Download or read book Pathologic Basis of Veterinary Disease Inkling E Book written by James F. Zachary and published by Elsevier Health Sciences. This book was released on 2016-05-23 with total page 1837 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnose and manage diseases using the newest information and research! Pathologic Basis of Veterinary Disease – Expert Consult, 6th Edition provides complete, illustrated coverage of both general pathology and the pathology of organ systems of domestic animals. Addressing species from dogs and cats to pigs and cattle — and many more — this reference describes the lesions and pathogeneses of diseases, how cells and tissues respond to injury, and the interplay of host defense mechanisms with microbes and injurious agents. Updates include the latest scientific advances and diagnostic information. Written by a team of expert contributors, this book includes an Expert Consult website with access to the complete digital book plus thousands of images and guidelines for sample acquisition and for performing a complete necropsy. Complete coverage of both general pathology and pathology of organ systems is provided in one convenient resource, and includes the latest information available. Over 20 recognized experts deliver the most relevant information for the practitioner, student, or individual preparing for the American College of Veterinary Pathology board examination. UPDATED content on cellular and organ system pathology includes the latest insights into the science of inflammation, healing, and molecular carcinogenesis, as well as expanded coverage of genetics and disease. Over 2,100 full-color illustrations include color schematics, flow charts, and diagrammatic representations of disease processes as well as summary tables and boxes, making it easier to understand difficult concepts. Clear, up-to-date explanations of disease mechanisms describe cell, tissue, and organ response to injury and infection. Easy-to-follow organization for each systemic disease chapter includes a brief review of basic principles related to anatomy, structure, and function, followed by congenital and functional abnormalities and discussions of infectious disease responses, helping you apply principles to veterinary practice. Expert Consult website provides the reader with the complete digital text plus: An image collection; guidelines for performing a complete, systematic necropsy and appropriate sample acquisition for all organ systems; a comprehensive glossary; and an appendix of photographic techniques in veterinary pathology. NEW line drawings and schematic diagrams depict current concepts about pathogeneses and lesions of veterinary diseases. NEW! Essential Concept boxes in each basic pathology chapter break down long and complicated topics, making it easier to understand lesions and pathogeneses in the ‘organ system’ chapters. NEW! Key Readings Index at the beginning of each chapter includes page numbers, making important information easy to locate.

Download or read book Humoral Immunity in Neurological Diseases written by D. Karcher and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Studies from the Dept of Pathology written by Columbia University. College of Physicians and Surgeons. Dept. of Pathology and published by . This book was released on 1927 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Studies from the Department of Pathology of the College of Physicians and Surgeons Columbia University N Y reprints v 19 20 1923 27 written by Columbia University College of Physicians and Surgeons. Dept. of Pathology and published by . This book was released on 1925 with total page 1086 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Studies from the Department of Pathology of the College of Physicians and Surgeons Columbia University N Y Reprints written by Columbia University. College of Physicians and Surgeons. Department of Pathology and published by . This book was released on 1927 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Genetics and Epigenetics of Psychiatric Diseases 2nd Edition written by Cunyou Zhao and published by Frontiers Media SA. This book was released on 2020-10-09 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychiatric diseases have a highly complex etiology, aggregating in families but not segregating in a traditional Mendelian manner. Recent approaches to understanding the causes of psychiatric disease have focused on describing the genetic contribution to major psychiatric illnesses; the use of large-scale genome-wide association studies (GWAS) and exome sequencing has enabled a systematic exploration of genetic risk factors and identified over 100 independent genomic loci significantly associated with psychiatric diseases; however, there remains uncertainty about the causal genes involved in disease pathogenesis, and how their function is regulated. Since many GWAS variants reside in non-coding regions, the disease-associated common variants might be enriched in regulatory domains, including enhancers and regions of active chromatin state. These lead us to focus on the possible role of non-sequence-based genomic variation in health and disease. Of particular interest are epigenetic modifications that regulate gene expression through modifications to DNA, RNA, histone proteins, and chromatin. The availability of high-throughput profiling methods for quantifiying epigenomic modifications in large numbers of samples has enabled us to perform epigenome-wide association studies (EWAS) aimed at screening methylomic variations associated with environmental exposure and disease. Thus systematic integration of genetic, epigenetic and epidemiological approaches will contribute to improving our understanding of the molecular mechanisms underlying disease phenotypes.

Download or read book Neurotherapeutics in the Era of Translational Medicine written by Richard A. Smith and published by Academic Press. This book was released on 2020-11-28 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the first time in history, there is now hope for treating neurological disorders that had previously been considered untreatable. The remarkable confluence of events that has heralded this is the focus of Neurotherapeutics in the Era of Translational Medicine. This anthology, written by many of the prominent scientists and researchers in the field of biotechnology, recounts the breathtaking advances that are revolutionizing treatment for disorders such as amyotrophic lateral sclerosis?, spinal muscular atrophy, multiple sclerosis, Parkinson’s disease, myasthenia gravis, migraine, and glioblastoma. The "story behind the story" of these translational efforts is told, with authors depicting the ups and downs encountered on the path of their drug discovery and development effort. In parallel with this path, advances in identifying novel biomarkers and disease models are summarized, as are contemporary issues focusing on clinical trial design, bioethics, innovative funding strategies, and collaborations between government and academia in an effort to facilitate breakthrough treatments. The book is written by members of the biotech and pharmaceutical ecosystem for those who belong to it and aspire to become part of it. Comprehensive review on the progress of translational research in neurotherapeutics for neurologic disorders Discusses important issues in clinical trials such as design and ethical issues Written for neuroscientists, neurologists and pharmacologists

Download or read book Posttraumatic Epilepsy written by Carrie R. Jonak and published by Elsevier. This book was released on 2022-10-21 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Posttraumatic Epilepsy: Basic and Clinical Aspects provides a synthesized resource on the recent basic and clinical science developments in the field of posttraumatic epilepsy. This book provides a clear understanding of the history of studies and epidemiology of posttraumatic epilepsy after head injury. The book also considers the neuropathology of posttraumatic epilepsy and clinical trials of antiepileptogenic agents evaluated after traumatic brain injury. The book covers the basic science of animal models of traumatic brain injury and the necessary and sufficient changes that must occur to generate epilepsy after head trauma. The authors explore potential mechanisms and novel therapeutic approaches to prevent posttraumatic epilepsy. The book is written for basic and clinical researchers in neuroscience as well as for clinicians treating patients with epilepsy. Reviews the history and epidemiology of posttraumatic epilepsy Considers the neuropathology of posttraumatic epilepsy Synthesizes studies demonstrating risk factors for susceptibility to epilepsy after head trauma Reviews animal models of traumatic brain injury Addresses our current understanding of mechanisms of posttraumatic epilepsy Explores novel therapeutic approaches to prevent posttraumatic epilepsy