Download or read book OECD Series on Testing and Assessment Detailed Review Paper on the Use of Metabolising Systems for In Vitro Testing of Endocrine Disruptors written by OECD and published by OECD Publishing. This book was released on 2014-09-03 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Detailed Review Paper describes some endocrine pathways that have been shown to be susceptible to environmental endocrine disruption and whose disruption could contribute to increasing incidents of some disorders in humans and wildlife populations.

Download or read book OECD Series on Testing and Assessment Detailed Review Paper on the State of the Science on Novel In Vitro and In Vivo Screening and Testing Methods and Endpoints for Evaluating Endocrine Disruptors written by OECD and published by OECD Publishing. This book was released on 2012-08-21 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: This paper provides methods for both the mechanistic evaluation of the action of Endocrine Disrupter Chemicals (EDCs).

Download or read book OECD Guidelines for the Testing of Chemicals OECD Series on Testing and Assessment Detailed Review Paper on Fish Screening Assays for the Detection of Endocrine Active Substances written by OECD and published by OECD Publishing. This book was released on 2004-11-01 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Detailed Review Paper (DRP) is intended to provide the current state-of-the-knowledge in the area of fish screening assays for chemicals active at the endocrine level on the reproductive system of test animals.

Download or read book OECD Series on Testing and Assessment New Scoping Document on in vitro and ex vivo Assays for the Identification of Modulators of Thyroid Hormone Signalling written by OECD and published by OECD Publishing. This book was released on 2014-07-11 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: This scoping document aims at bringing forward relevant in vitro and ex vivo thyroid assays to the attention of OECD member countries, to provide recommendations for their development/use, and also, to identify aspects/blocks of the thyroid signalling pathways that are not covered and would ...

Download or read book OECD Series on Testing and Assessment Detailed Review Paper DRP on Molluscs Life cycle Toxicity Testing written by OECD and published by OECD Publishing. This book was released on 2014-09-03 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: This paper reviews what is known about the responses of molluscs to endocrine disrupting chemicals (EDCs), to consider whether it would be desirable and feasible to standardise mollusc-based partial- and full-lifecycle tests that are sensitive to EDCs and to other chemicals.

Download or read book OECD Series on Testing and Assessment Revised Guidance Document 150 on Standardised Test Guidelines for Evaluating Chemicals for Endocrine Disruption written by OECD and published by OECD Publishing. This book was released on 2018-09-03 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guidance document was originally published in 2012 and updated in 2018 to reflect new and updated OECD test guidelines, as well as reflect on scientific advances in the use of test methods and assessment of the endocrine activity of chemicals.

Download or read book OECD Series on Testing and Assessment Guidance Document on Good In Vitro Method Practices GIVIMP written by OECD and published by OECD Publishing. This book was released on 2018-12-10 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an international regulatory context. To foster confidence in in vitro alternatives to animal testing, the test methods and conditions under which ...

Download or read book Guidance Document on Standardised Test Guidelines for Evaluating Chemicals for Endocrine Disruption written by OECD and published by OECD Publishing. This book was released on 2014-09-03 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document is a tool to support regulatory authorities’ decisions on the hazard of specific chemicals when they receive test results from a Test Guideline (TG) or draft TG for the screening/testing of chemicals for endocrine disrupting properties.

Download or read book OECD Series on Testing and Assessment The Adverse Outcome Pathway for Skin Sensitisation Initiated by Covalent Binding to Proteins written by OECD and published by OECD Publishing. This book was released on 2014-09-03 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document describes the state of knowledge of the adverse outcome pathway (AOP) for skin sensitisation initiated by covalent binding to proteins, assesses the weight-of-evidence supporting the AOP, identifies the key events, and identifies databases containing test results related to key events.

Download or read book OECD Series on Testing and Assessment Fish Toxicity Testing Framework written by OECD and published by OECD Publishing. This book was released on 2014-09-03 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document presents a review of fish toxicity testing for the regulatory purpose of chemical safety. The main focus is on fish toxicity, but fish bioaccumulation is also considered where relevant.

Download or read book OECD Series on Testing and Assessment The Guidance Document for Using the OECD Q SAR Application Toolbox to Develop Chemical Categories According to the OECD Guidance on Grouping Chemicals written by OECD and published by OECD Publishing. This book was released on 2014-09-03 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document provides guidance on how to use the OECD (Q)SAR Application Toolbox to build chemical categories according to the OECD Guidance on Grouping of Chemicals. It is part of an overall effort to provide guidance on the use of the (Q)SAR Application Toolbox.

Download or read book OECD Series on Testing and Assessment Guidance Document 116 on the Conduct and Design of Chronic Toxicity and Carcinogenicity Studies Supporting Test Guidelines 451 452 and 453 Second edition written by OECD and published by OECD Publishing. This book was released on 2014-09-03 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guidance provides additional information on the conduct of studies performed using Test Guidelines 451, 452 and Test Guideline 453.

Download or read book OECD Guidelines for the Testing of Chemicals OECD Series on Testing and Assessment Detailed Review Paper on Fish Screening Assays for the Detection of Endocrine Active Substances written by OECD and published by OECD Publishing. This book was released on 2004-11-01 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Detailed Review Paper (DRP) is intended to provide the current state-of-the-knowledge in the area of fish screening assays for chemicals active at the endocrine level on the reproductive system of test animals.

Download or read book OECD Guidelines for the Testing of Chemicals OECD Series on Testing and Assessment Detailed Review Paper Appraisal of Test Methods for Sex Hormone Disrupting Chemicals written by OECD and published by OECD Publishing. This book was released on 2002-05-10 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: This documents servies as the basis for the first step in the consideration and development of OECD Test Guidelines for the testing of chemicals for endocrine-disrupting effects.

Download or read book OECD Series on Testing and Assessment Guidance Document on the Honey Bee Apis Mellifera L Brood test Under Semi field Conditions written by OECD and published by OECD Publishing. This book was released on 2014-09-03 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt: The method described in this guidance document assesses the effects of plant protection products (PPPs), and has been validated using the active Fenoxycarb, which is known to act as an insect growth regulator (IGR), to the honey bee brood (Apis mellifera L.).

Download or read book Series on Pesticides and Biocides Guidance Document on Overview of Residue Chemistry Studies Second Edition written by OECD and published by OECD Publishing. This book was released on 2009-07-28 with total page 93 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Overview Guidance Document summarises the major guidance aspects provided in the OECD Guidelines for the Testing of Chemicals, Section 5. This document also develops an approach for a Global Maximum Residue Limit (MRL) process to achieve use of a single globally acceptable feeding study for MRL setting and risk assessment for livestock food commodities that involves four key components: 1) Harmonised Guidance for the Definition of Residue; 2) Reasonable Worst Case Animal Diets/Maximum Reasonably Balanced Diet; 3) Harmonised Table of Livestock Feed Commodities; and 4) Definition of Reasonable Worst Case Livestock Feeding Levels.

Download or read book OECD Guidelines for the Testing of Chemicals Section 2 Test No 231 Amphibian Metamorphosis Assay written by OECD and published by OECD Publishing. This book was released on 2009-09-08 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes an amphibian metamorphosis assay intended to screen substances which may interfere with the normal functioning of the hypothalamo-pituitary-thyroid axis. The assay was validated with the species Xenopus laevis, which is ...