Download or read book OECD Series on Testing and Assessment Current Approaches in the Statistical Analysis of Ecotoxicity Data A guidance to application annexes to this publication exist as a separate document written by OECD and published by OECD Publishing. This book was released on 2006-05-09 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document describes the main statistical methods used for analysis of data from ecotoxicological studies .
Download or read book Statistical Analysis of Ecotoxicity Studies written by John W. Green and published by John Wiley & Sons. This book was released on 2018-07-04 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the issues relevant to the design, analysis, and interpretation of toxicity studies that examine chemicals for use in the environment Statistical Analysis of Ecotoxicity Studies offers a guide to the design, analysis, and interpretation of a range of experiments that are used to assess the toxicity of chemicals. While the book highlights ecotoxicity studies, the methods presented are applicable to the broad range of toxicity studies. The text contains myriad datasets (from laboratory and field research) that clearly illustrate the book's topics. The datasets reveal the techniques, pitfalls, and precautions derived from these studies. The text includes information on recently developed methods for the analysis of severity scores and other ordered responses, as well as extensive power studies of competing tests and computer simulation studies of regression models that offer an understanding of the sensitivity (or lack thereof) of various methods and the quality of parameter estimates from regression models. The authors also discuss the regulatory process indicating how test guidelines are developed and review the statistical methodology in current or pending OECD and USEPA ecotoxicity guidelines. This important guide: Offers the information needed for the design and analysis to a wide array of ecotoxicity experiments and to the development of international test guidelines used to assess the toxicity of chemicals Contains a thorough examination of the statistical issues that arise in toxicity studies, especially ecotoxicity Includes an introduction to toxicity experiments and statistical analysis basics Includes programs in R and excel Covers the analysis of continuous and Quantal data, analysis of data as well as Regulatory Issues Presents additional topics (Mesocosm and Microplate experiments, mixtures of chemicals, benchmark dose models, and limit tests) as well as software Written for directors, scientists, regulators, and technicians, Statistical Analysis of Ecotoxicity Studies provides a sound understanding of the technical and practical issues in designing, analyzing, and interpreting toxicity studies to support or challenge chemicals for use in the environment.
Download or read book Marine Ecotoxicology written by Julián Blasco and published by Academic Press. This book was released on 2016-08-05 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Marine Ecotoxicology: Current Knowledge and Future Issues is the first unified resource to cover issues related to contamination, responses, and testing techniques of saltwater from a toxicological perspective. With its unprecedented focus on marine environments and logical chapter progression, this book is useful to graduate students, ecotoxicologists, risk assessors, and regulators involved or interested in marine waters. As human interaction with these environments increases, understanding of the pollutants and toxins introduced into the oceans becomes ever more critical, and this book builds a foundation of knowledge to assist scientists in studying, monitoring, and making decisions that affect both marine environments and human health. A team of world renowned experts provide detailed analyses of the most common contaminants in marine environments and explain the design and purpose of toxicity testing methods, while exploring the future of ecotoxicology studies in relation to the world's oceans. As the threat of increasing pollution in marine environments becomes an ever more tangible reality, Marine Ecotoxicology offers insights and guidance to mitigate that threat. - Provides practical tools and methods for assessing and monitoring the accumulation and effects of contaminants in marine environments - Unites world renowned experts in marine ecotoxicology to deliver thorough and diverse perspectives - Builds the foundation required for risk assessors and regulators to adequately assess and monitor the impact of pollution in marine environments - Offers helpful insights and guidance to graduate students, ecotoxicologists, risk assessors, and regulators interested in mitigating threats to marine waters
Download or read book OECD Guidelines for the Testing of Chemicals Section 2 Test No 249 Fish Cell Line Acute Toxicity The RTgill W1 cell line assay written by OECD and published by OECD Publishing. This book was released on 2021-06-18 with total page 51 pages. Available in PDF, EPUB and Kindle. Book excerpt: The RTgill-W1 cell line assay describes a 24-well plate format fish cell line acute toxicity test using the permanent cell line from rainbow trout (Oncorhynchus mykiss) gill, RTgill-W1. After 24 h of exposure to the test chemical, cell viability is assessed based on three fluorescent cell viability indicator dyes, measured on the same set of cells. Resazurin enters the cells in its non-fluorescent form and is converted to the fluorescent product, resorufin, by mitochondrial, microsomal or cytoplasmic oxidoreductases.
Download or read book OECD Guidelines for Testing of Chemicals written by Organisation for Economic Co-operation and Development and published by Organisation for Economic Co-operation and Development ; [Montréal : Renouf]. This book was released on 1981 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mixture Toxicity written by Cornelis A. M. van Gestel and published by CRC Press. This book was released on 2016-04-19 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decade and a half, great progress has been made in the development of concepts and models for mixture toxicity, both in human and environmental toxicology. However, due to their different protection goals, developments have often progressed in parallel but with little integration. Arguably the first book to clearly link ecotoxicology an
Download or read book Test No 421 Reproduction Developmental Toxicity Screening Test written by OECD and published by OECD Publishing. This book was released on 1995-07-27 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt: The test substance is administered in graduated doses to several groups of males and females. Males should be dosed for a minimum of four weeks. Females should be dosed throughout the study, so approximately 54 days. This Test Guideline is designed ...
Download or read book Functional Testing of Aquatic Biota for Estimating Hazards of Chemicals written by John Cairns and published by ASTM International. This book was released on 1988 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Methods for Measuring the Toxicity and Bioaccumulation of Sediment associated Contaminants with Freshwater Invertebrates written by and published by . This book was released on 1994 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sediment contamination is a widespread environmental problem that can potentially pose a threat to a variety of aquatic ecosystems. The sediment test methods in this manual will be used by The United States Environmental Protection Agency (USEPA) to make decisions under a range of statutory authorities concerning such issues as: dredged material disposal, registration of pesticides and toxic substances, superfound site assessment, and assessment and cleanup of hazardous waste treatment, storage, and disposal facilities. The use of uniform sediment testing procedures by USEPA programs is expected to increase data accuracy and precision, facilitate test replication, increase the comparative value of test results, and ultimately, increase the efficiency of regulatory processes requiring sediment tests.
Download or read book Sediment Quality Assessment written by Graeme Batley and published by CSIRO PUBLISHING. This book was released on 2016-02-01 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contaminated sediments represent an ongoing threat to the health of aquatic ecosystems. The assessment of sediment quality is, therefore, an important concern for environmental regulators. Sediment quality guidelines are now well established in regulatory frameworks worldwide; however, practical guidance that covers all of the key aspects of sediment quality assessment is not readily available. In 2005, CSIRO published its highly cited Handbook for Sediment Quality Assessment. In the ensuing period, the science has advanced considerably. This practical guide is a revised and much expanded second edition, which will be a valuable tool for environmental practitioners. Written by experts in the field, it provides coverage of: sediment sampling; sample preparation; chemical analysis; ecotoxicology; bioaccumulation; biomarkers; and ecological assessment. In addition, detailed appendices describe protocols for many of the tests to be used.
Download or read book Life Cycle Assessment written by Kun-Mo Lee and published by . This book was released on 2004 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bioaccumulation Testing and Interpretation for the Purpose of Sediment Quality Assessment written by and published by . This book was released on 2000 with total page 828 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Regulatory Toxicology written by Franz-Xaver Reichl and published by Springer. This book was released on 2014-03-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will be written by experts for professionals, scientists and all those involved in toxicological data generation and decision-making. It is the updated and expanded version of a monograph published in German in 2004. Chemical safety is regulated on various levels including production, storage, transport, handling, disposal or labelling. This book deals comprehensively with the safety-ensuring methods and concepts employed by regulatory agencies, industry and academics. Toxicologists use experimental and scientific approaches for data collection, e.g. about chemical hazards, physicochemical features or toxicokinetics. The respective experimental methods are described in the book. Toxicologists also deal with much insecurity in the exposure and effect scenarios during risk assessment. To overcome these, they have different extrapolation methods and estimation procedures at their disposal. The book describes these methods in an accessible manner. Differing concepts from one regulation area to another are also covered. Reasons and consequences become evident when reading the book. Altogether, the book Regulatory Toxicology will serve as an excellent reference.
Download or read book Globally Harmonized System of Classification and Labelling of Chemicals GHS written by and published by Columbia Books. Incorporated. This book was released on 2015 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) addresses classification and labelling of chemicals by types of hazards. It provides the basis for worldwide harmonization of rules and regulations on chemicals and aims at enhancing the protection of human health and the environment during their handling, transport and use by ensuring that the information about their physical, health and environmental hazards is available. The sixth revised edition includes, inter alia, a new hazard class for desensitized explosives and a new hazard category for pyrophoric gases; miscellaneous amendments intended to further clarify the criteria for some hazard classes (explosives, specific target organ toxicity following single exposure, aspiration hazard, and hazardous to the aquatic environment) and to complement the information to be included in section 9 of the Safety Data Sheet; revised and further rationalized precautionary statements; and an example of labelling of a small packaging in Annex 7.
Download or read book Life Cycle Assessment LCA written by Allan Astrup Jensen and published by . This book was released on 1998 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Life Cycle Assessment
Download or read book Coal Tar Creosote written by C. Melber and published by WHO. This book was released on 2004 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: On cover: IPCS International Programme on Chemical Safety. Published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organization and the World Health Organization, and produced within the framework of the Inter-organization Programme for the Sound Management of Chemicals (IOMC)
Download or read book Australian and New Zealand Guidelines for Fresh and Marine Water Quality written by and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
