Download or read book Test No 421 Reproduction Developmental Toxicity Screening Test written by OECD and published by OECD Publishing. This book was released on 1995-07-27 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt: The test substance is administered in graduated doses to several groups of males and females. Males should be dosed for a minimum of four weeks. Females should be dosed throughout the study, so approximately 54 days. This Test Guideline is designed ...

Download or read book Test No 422 Combined Repeated Dose Toxicity Study with the Reproduction Developmental Toxicity Screening Test written by OECD and published by OECD Publishing. This book was released on 1996-03-22 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: The test substance is administered in graduated doses to several groups of males and females. Males should be dosed for a minimum of four weeks; females should be dosed throughout the study (approximately 54 days). Normally, matings “one male to one ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 415 One Generation Reproduction Toxicity Study written by OECD and published by OECD Publishing. This book was released on 2019-03-01 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline for reproduction testing is designed to provide general information concerning the effects of a test substance (Solid, liquid, gas or vapour) on male and female reproductive performance. The test substance is administered orally ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 416 Two Generation Reproduction Toxicity written by OECD and published by OECD Publishing. This book was released on 2001-01-22 with total page 13 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline for two-generation reproduction testing is designed to provide general information concerning the effects of a test substance on the integrity and performance of the male and female reproductive systems, and on the growth and ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 414 Prenatal Developmental Toxicity Study written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 11 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline for developmental toxicity testing is designed to provide general information concerning the effects of prenatal exposure on the pregnant test animal and on the developing organism. The test substance is normally administered to ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 443 Extended One Generation Reproductive Toxicity Study written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 25 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline is designed to provide an evaluation of reproductive and developmental effects that may occur as a result of pre- and postnatal chemical exposure as well as an evaluation of systemic toxicity in pregnant and lactating females and ...

Download or read book OECD Guidelines for Testing of Chemicals written by Organisation for Economic Co-operation and Development and published by Organisation for Economic Co-operation and Development ; [Montréal : Renouf]. This book was released on 1981 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Test No 443 Extended One Generation Reproductive Toxicity Study written by OECD and published by OECD Publishing. This book was released on 2011-07-28 with total page 25 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline is designed to provide an evaluation of reproductive and developmental effects that may occur as a result of pre- and postnatal chemical exposure as well as an evaluation of systemic toxicity in pregnant and lactating females and ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 420 Acute Oral Toxicity Fixed Dose Procedure written by OECD and published by OECD Publishing. This book was released on 2002-02-08 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: A principle of the method is that in the main study only moderately toxic doses are used, and the administration of doses that are expected to be lethal should be avoided. This Guideline is intended primarily for use with rat. Groups of animals of a ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 482 Genetic Toxicology DNA Damage and Repair Unscheduled DNA Synthesis in Mammalian Cells in vitro written by OECD and published by OECD Publishing. This book was released on 1986-10-23 with total page 7 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Test Guideline for Unscheduled DNA Synthesis (UDS) in mammalian cells in vitro describes procedures utilizing primary cultures, human lymphocytes or established cell lines, to detect DNA repair synthesis after excision and removal of a stretch ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 452 Chronic Toxicity Studies written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 432 In Vitro 3T3 NRU Phototoxicity Test written by OECD and published by OECD Publishing. This book was released on 2019-06-18 with total page 15 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes a method to evaluate photo-cytotoxicity by the relative reduction in viability of cells exposed to the chemical in the presence versus absence of light. Balb/c 3T3 cells are maintained in culture for 24 h for formation ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Health Effects Summary of Considerations in the Report from the OECD Expert Groups on Short Term and Long Term Toxicology written by OECD and published by OECD Publishing. This book was released on 2006-09-11 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Health Effects Test No 436 Acute Inhalation Toxicity Acute Toxic Class Method written by OECD and published by OECD Publishing. This book was released on 2009-09-08 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt: The method described by this Test Guideline provides information that allows hazard assessment for short-term exposure to a test article by inhalation, and allows the substance to be classified according to the Globally Harmonized System of ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 423 Acute Oral toxicity Acute Toxic Class Method written by OECD and published by OECD Publishing. This book was released on 2002-02-08 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a test guideline for testing for Acute Oral Tosxidity using the Acute Toxic Class Method.

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 403 Acute Inhalation Toxicity written by OECD and published by OECD Publishing. This book was released on 2024-06-25 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from short-term exposure to a test article (gas, vapour or aerosol/particulate test article) by inhalation. The revised Test Guideline describes two studies: a traditional LC50 ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 422 Combined Repeated Dose Toxicity Study with the Reproduction Developmental Toxicity Screening Test written by OECD and published by OECD Publishing. This book was released on 2016-07-29 with total page 19 pages. Available in PDF, EPUB and Kindle. Book excerpt: This screening Test Guideline describes the effects of a test chemical on male and female reproductive performance. It has been updated with endocrine disruptor endpoints, in particular measure of anogenital distance and male nipple retention in pups and thyroid examination.