Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Health Effects Test No 436 Acute Inhalation Toxicity Acute Toxic Class Method written by OECD and published by OECD Publishing. This book was released on 2009-09-08 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt: The method described by this Test Guideline provides information that allows hazard assessment for short-term exposure to a test article by inhalation, and allows the substance to be classified according to the Globally Harmonized System of ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 423 Acute Oral toxicity Acute Toxic Class Method written by OECD and published by OECD Publishing. This book was released on 2002-02-08 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a test guideline for testing for Acute Oral Tosxidity using the Acute Toxic Class Method.

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 433 Acute Inhalation Toxicity Fixed Concentration Procedure written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 21 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from short-term exposure to a test chemical by inhalation. It is a principle of the method that only moderately toxic concentrations are used so that ‘evident toxicity’, rather than death/moribundity is used as an endpoint, and ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 403 Acute Inhalation Toxicity written by OECD and published by OECD Publishing. This book was released on 2024-06-25 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from short-term exposure to a test article (gas, vapour or aerosol/particulate test article) by inhalation. The revised Test Guideline describes two studies: a traditional LC50 ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 420 Acute Oral Toxicity Fixed Dose Procedure written by OECD and published by OECD Publishing. This book was released on 2002-02-08 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: A principle of the method is that in the main study only moderately toxic doses are used, and the administration of doses that are expected to be lethal should be avoided. This Guideline is intended primarily for use with rat. Groups of animals of a ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 425 Acute Oral Toxicity Up and Down Procedure written by OECD and published by OECD Publishing. This book was released on 2022-06-30 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt: The method permits estimation of an LD50 with a confidence interval and the results allow a substance to be classified for acute toxicity according to the Globally Harmonised System of classification and labelling of chemicals. It is easiest to ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 412 Subacute Inhalation Toxicity 28 Day Study written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised Test Guideline 412 (TG 412) has been designed to fully characterize test article toxicity by the inhalation route following repeated exposure for a limited period of time (28 days), and to provide data for quantitative inhalation risk ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 413 Subchronic Inhalation Toxicity 90 day Study written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 15 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised Test Guideline has been designed to fully characterize test article toxicity by the inhalation route for a subchronic duration (90 days), and to provide robust data for quantitative inhalation risk assessments. Groups of 10 male and 10 ...

Download or read book Laboratory Animal Welfare written by Kathryn Bayne and published by Academic Press. This book was released on 2013-09-02 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory Animal Welfare provides a comprehensive, up-to-date look into the new science of animal welfare within laboratory research. Animals specifically considered include rodents, cats and dogs, nonhuman primates, agricultural animals, avian animals and aquatic animals. The book examines the impact of experiment design and environment on animal welfare, as well as emergency situations and euthanasia practices. Readers will benefit from a review of regulations and policy guidelines concerning lab animal use, as well as information on assessing animal welfare. With discussions of the history and ethics of animals in research, and a debate on contemporary and international issues, this book is a go-to resource for laboratory animal welfare.

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 452 Chronic Toxicity Studies written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Health Effects Summary of Considerations in the Report from the OECD Expert Groups on Short Term and Long Term Toxicology written by OECD and published by OECD Publishing. This book was released on 2006-09-11 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book A Practical Guide to Toxicology and Human Health Risk Assessment written by Laura Robinson and published by John Wiley & Sons. This book was released on 2018-11-20 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicology – the study of the adverse effects of chemicals on living organisms is the cornerstone to all aspects of chemical safety and knowledge of the subject is needed in a wide spectrum of fields from the chemical industry to medicine, emergency services, forensics, and regulatory science. Toxicology involves the study of symptoms, mechanisms, treatments and detection of poisoning ... especially the poisoning of people. The many problems arising from a poor understanding of toxicology and its applications in hazard communication and chemical safety motivated the author's training courses and webinars, leading to this valuable book. Providing a practical and accessible guide, A Practical Guide to Toxicology and Human Health Risk Assessment enables readers to quickly build up knowledge and understanding of toxicology and its use in hazard identification, which is a fundamental part of chemical risk assessment. The book also covers current toxicological testing strategies and the use of physicochemical test data in hazard identification and exposure assessment. Examples are provided throughout the book to highlight important issues along with a summary of the key points that have been covered in each of the respective chapters. The book concludes with a listing of online resources on toxicology and risk assessment.

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 411 Subchronic Dermal Toxicity 90 day Study written by OECD and published by OECD Publishing. This book was released on 1981-05-12 with total page 9 pages. Available in PDF, EPUB and Kindle. Book excerpt: This study relates to the analysis, via dermal application, of the health hazards of solid or liquid test substance. It may be carried out after initial information obtained by acute testing. This method is composed of the main test and the limit ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 424 Neurotoxicity Study in Rodents written by OECD and published by OECD Publishing. This book was released on 1997-07-21 with total page 15 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline has been designed to obtain the information necessary to confirm or to further characterise the potential neurotoxicity of chemicals in adult animals. This Test Guideline is designed for use with the rat. It specifically ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 410 Repeated Dose Dermal Toxicity 21 28 day Study written by OECD and published by OECD Publishing. This book was released on 1981-05-12 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: This study relates to the analysis, via dermal application, of the health hazard of solid or liquid test substance. This method is composed of two tests: the main test and the limit test. This Test Guideline is intended for use with the adult rat ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 401 Acute Oral Toxicity written by OECD and published by OECD Publishing. This book was released on 1987-02-24 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt: The OECD Guidelines for the Testing of Chemicals are a collection of about 100 of the most relevant internationally agreed testing methods used by government, industry and independent laboratories to identify and characterise potential hazards of ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 2 Test No 213 Honeybees Acute Oral Toxicity Test written by OECD and published by OECD Publishing. This book was released on 1998-09-21 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline is a laboratory test method, designed to assess the oral acute toxicity of pesticides and other chemicals, to adult worker honeybees. Adult worker honeybees are exposed to five doses in a geometric series of the test substance ...