Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Test No 319A Determination of in vitro intrinsic clearance using cryopreserved rainbow trout hepatocytes RT HEP written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Test Guideline (TG) describes the use of cryopreserved rainbow trout (Oncorhynchus mykiss) hepatocytes (RT-HEP) as a metabolising system to determine the clearance (CL, IN VITRO, INT) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the RT-HEP ...
Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Test No 319A Determination of in vitro intrinsic clearance using cryopreserved rainbow trout hepatocytes RT HEP written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Test Guideline (TG) describes the use of cryopreserved rainbow trout (Oncorhynchus mykiss) hepatocytes (RT-HEP) as a metabolising system to determine the clearance (CL, IN VITRO, INT) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the RT-HEP ...
Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Test No 319B Determination of in vitro intrinsic clearance using rainbow trout liver S9 sub cellular fraction RT S9 written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Test Guideline (TG) describes the use of liver S9 sub-cellular fraction (RT-S9) of rainbow trout (Oncorhynchus mykiss) as a metabolising system to determine the clearance (CL, IN VITRO, INT ) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the ...
Download or read book Test No 319B Determination of in Vitro Intrinsic Clearance Using Rainbow Trout Liver S9 Sub cellular Fraction RT S9 written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Test No 305 Bioaccumulation in Fish Aqueous and Dietary Exposure written by OECD and published by OECD Publishing. This book was released on 2012-10-02 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes a procedure for characterising the bioconcentration potential of substances in fish, using an aqueous (standard and minimised tests) or dietary exposure, under flow-through conditions (but semi-static regimes are ...
Download or read book Human and Ecological Risk Assessment written by Dennis J. Paustenbach and published by John Wiley & Sons. This book was released on 2024-04-15 with total page 1319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understand the fundamentals of human risk assessment with this introduction and reference Human risk assessments are a precondition for virtually all industrial action or environmental regulation, all the more essential in a world where chemical and environmental hazards are becoming more abundant. These documents catalog potential environmental, toxicological, ecological, or other harms resulting from a particular hazard, from chemical spills to construction projects to dangerous workplaces. They turn on a number of variables, of which the most significant is the degree of human exposure to the hazardous agent or process. Human and Ecological Risk Assessment combines the virtues of a textbook and reference work to introduce and analyze these vital documents. Beginning with the foundational theory of human health risk assessment, it then supplies case studies and detailed analysis illustrating the practice of producing risk assessment documents. Fully updated and authored by leading authorities in the field, the result is an indispensable work. Readers of the second edition of Human and Ecological Risk Assessment will also find: Over 40 entirely new case studies reflecting the latest in risk assessment practice Detailed discussion of hazards including air emissions, contaminated food and soil, hazardous waste sites, and many more Case studies from multiple countries to reflect diverse international standards Human and Ecological Risk Assessment is ideal for professionals and advanced graduate students in toxicology, industrial hygiene, occupational medicine, environmental science, and all related subjects.
Download or read book Ecotoxicology of Nanoparticles in Aquatic Systems written by Julian Blasco and published by CRC Press. This book was released on 2019-07-19 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of nanoparticles in medicine, industrial, and other applications has triggered an interest in their potential. This book explores the use of nanoparticles related to their occurrence in the environment, their impact on biota in aquatic systems, application of new methodologies, and changes associated with new global scenarios. The book also covers the bioaccumulation and internalization of nanoparticles as key aspects to assess their uptake and discusses the methodologies for testing ENPs ecotoxicity at different trophic levels.
Download or read book Ecotoxicology of Nanoparticles in Aquatic Systems written by Julian Blasco and published by CRC Press. This book was released on 2019-07-19 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of nanoparticles in medicine, industrial, and other applications has triggered an interest in their potential. This book explores the use of nanoparticles related to their occurrence in the environment, their impact on biota in aquatic systems, application of new methodologies, and changes associated with new global scenarios. The book also covers the bioaccumulation and internalization of nanoparticles as key aspects to assess their uptake and discusses the methodologies for testing ENPs ecotoxicity at different trophic levels.
Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Test No 312 Leaching in Soil Columns written by OECD and published by OECD Publishing. This book was released on 2004-11-23 with total page 15 pages. Available in PDF, EPUB and Kindle. Book excerpt: The method described in this Test Guideline is based on soil column chromatography in disturbed soil. Two types of experiments are performed to determine (i) the leaching potential of the test substance, and (ii) the leaching potential of ...
Download or read book OECD Series on Testing and Assessment Guidance Document on Good In Vitro Method Practices GIVIMP written by OECD and published by OECD Publishing. This book was released on 2018-12-10 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an international regulatory context. To foster confidence in in vitro alternatives to animal testing, the test methods and conditions under which ...
Download or read book Toxicity Testing in the 21st Century written by National Research Council and published by National Academies Press. This book was released on 2007-10-05 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S. Environmental Protection Agency to review the state of the science and create a far-reaching vision for the future of toxicity testing. The book finds that developing, improving, and validating new laboratory tools based on recent scientific advances could significantly improve our ability to understand the hazards and risks posed by chemicals. This new knowledge would lead to much more informed environmental regulations and dramatically reduce the need for animal testing because the new tests would be based on human cells and cell components. Substantial scientific efforts and resources will be required to leverage these new technologies to realize the vision, but the result will be a more efficient, informative and less costly system for assessing the hazards posed by industrial chemicals and pesticides.
Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Test No 317 Bioaccumulation in Terrestrial Oligochaetes written by OECD and published by OECD Publishing. This book was released on 2010-07-23 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes procedures designed to assess bioaccumulation of chemicals in soil oligochaetes. The parameters which characterise the bioaccumulation of a substance include the bioaccumulation factor (BAF), the uptake rate constant ...
Download or read book Treatment of Hypertension with Urapidil written by Anthony Amery and published by . This book was released on 1986 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Anticoagulant Rodenticides and Wildlife written by Nico W. van den Brink and published by Springer. This book was released on 2017-11-09 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Commensal rodents pose health risks and cause substantial damage to property and food supplies. Rats have also invaded islands and pose a serious threat to native wildlife, particularly raptors and seabirds. Estimates of total damage from introduced rats range into the billions of dollars in developed countries. This book aims to provide a state-of-the-art overview of the scientific advancements in the assessment of exposure, effects and risks that currently used rodenticides may pose to non-target organisms in the environment, along with practical guidance for characterization of hazards. This will be discussed in relation to their efficacy, and the societal needs for rodent control, and discussion of risk mitigation and development of alternatives. The flow in the book is planned as: a. introduction and setting the scene b. problem description (risks and effects on non-targets and secondary poisoning, development of resistance) c. ; alternatives, regulation and risk mitigation d. conclusions and recommendations
Download or read book The Toxicology of Fishes written by Richard T. Di Giulio and published by CRC Press. This book was released on 2008-02-25 with total page 1102 pages. Available in PDF, EPUB and Kindle. Book excerpt: When looking for a book on fish toxicology, you might find one that discusses the biochemical and molecular aspects, or one that focuses aquatic toxicology in general. You can find resources that cover human and animal toxicology or ecotoxicology in general, but no up-to-date, comprehensive monograph devoted to the effects of chemical pollution on
Download or read book Fish Physiology The Multifunctional Gut of Fish written by and published by Academic Press. This book was released on 2010-10-21 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Multifunctional Gut of Fish provides a comprehensive synthesis and an integrative overview of the range of gut functions and their implications for organismal physiology. The highly diversified anatomy and functions of the gut, including nutrient uptake, immune barrier function, salt and water homeostasis and respiration, as well as neuroendocrine actions and control are covered in detail by leading authors. In addition, this volume explores the pronounced implications of gut function for whole animal integrative physiology and compensatory demands for non-gastrointestinal organs. As the first comprehensive reference to discuss the diverse morphological and functional adaptations of the gut, this volume provides an excellent resource for comparative physiologists, aquaculturists and biomedical researchers employing fish as model organisms for mammalian physiology. Includes chapters dedicated to anatomical and functional features of the gastro-intestinal tract of fish as well as integrative aspects of gut organ function Includes in depth coverage of recently recognized implications of feeding on salt homeostasis and acid-base balance Provides syntheses of implications of gut function for homeostasis Essential text for those interested in the wide diversity of functions performed by the gut
Download or read book Nutrient Requirements and Feeding of Finfish for Aquaculture written by Carl D. Webster and published by CABI. This book was released on 2002-02-01 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Good nutrition is fundamental to the success and sustainability of the aquaculture industry in terms of economics, fish health, high quality product production and minimizing environmental pollution. This book provides a unique, complete coverage of current information on nutrientrequirements, feed formulations and feeding practices of commercially important aquaculture species cultured around the world. Each chapter contains detailed feeding information on specific species and is written by an expert nutritionist on that species. The book is of interest to those workingprofessionally in the industry, graduate level students and researchers.
