Download or read book Ocular Angiogenesis an Issue of Ophthalmology Clinics written by James M. Cairo and published by Saunders. This book was released on 2006-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abnormal angiogenesis is frequently the final pathway leading to the vast majority of diseases that result in catastrophic loss of vision. This issue includes topics on molecular biology of choroidal neovascularization, immunologic aspects of choroidal neovascularization, role of VEGF in ocular angiogenesis, and Pegaptanib: treating neovascular AMD, plus much more.

Download or read book Ocular Angiogenesis written by Joyce Tombran-Tink and published by Springer Science & Business Media. This book was released on 2007-11-06 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading academic and pharmaceutical researchers and clinicians from many disciplines synthesize and summarize current clinical and basic knowledge concerning abnormal growth of blood vessels in the eye, the cause of major neovascular eye diseases. The authors also identify and assess the most promising approaches with potential for commercial exploitation and discuss the challenges encountered in developing therapeutics for ocular neovascular diseases. Highlights include illuminating chapters on gene therapy and novel drug delivery systems and excellent summaries of the newest therapeutic approaches.

Download or read book Therapy for Ocular Angiogenesis written by Arup Das and published by Lippincott Williams & Wilkins. This book was released on 2012-03-28 with total page 896 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ocular angiogenesis, or the abnormal growth of blood vessels in the eye, is the cause of major neovascular eye diseases. With the new era of anti-angiogenic therapies, ophthalmologists have started treating many ocular diseases including macular degeneration, diabetic retinopathy, and retinal vascular occlusion using anti-angiogenic drugs. This book covers the basic pathophysiology of ocular angiogenesis and strategies for inhibition. The authors discuss the "Principles" of anti-angiogenic therapy, pre-clinical studies, future drugs on the horizon, drug delivery, and the "Practice" of the therapy in many ocular diseases. The book also includes chapters on diabetic macular edema, and various therapeutic options for this condition. A companion website includes the fully searchable text and an image bank.

Download or read book Retinal and Choroidal Angiogenesis written by John Penn and published by Springer Science & Business Media. This book was released on 2008-01-19 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive, in-depth review of our current understanding of the growth of blood vessels within the eye. Novel therapeutic strategies for the treatment of ocular angiogenesis are discussed, as are the unique challenges presented by delivery of drugs to the eye. The book emphasizes basic principles rather than specific experimental results, although recently acquired data is frequently cited to illustrate points of broader theoretical significance.

Download or read book Anti Angiogenic Therapy in Ophthalmology written by Andreas Stahl and published by Springer. This book was released on 2016-05-13 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a concise overview over the pathology of retinal angiogenic diseases and explains why anti-angiogenic therapy is effective in so many patients. The reader is guided through the various clinical indications for anti-angiogenic therapy and made aware of its merits as well as current challenges and limitations. It is explained how, since its introduction for the treatment of exudative age-related macular degeneration in 2006, anti-angiogenic therapy has revolutionized the way in which we treat a range of ocular diseases. All of the authors are established experts in their respective fields who share their extensive knowledge and clinical experience with the reader. This book is both a valuable introduction to anti-angiogenic therapy in ophthalmology and a day-to-day companion for all ophthalmologists seeing patients with some of the most prevalent retinal diseases.

Download or read book Corneal Angiogenesis written by Gordon K. Klintworth and published by Springer. This book was released on 2011-09-22 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this research monograph, the noted scholar Dr. Gordon K. Klintworth brings together all the available information on the pathogenesis of corneal neovascularization. This book should be a valuable contribution to the medical literature of ophthalmology and clinical pathology. Despite its relatively simple structure the cornea possesses many unique properties. These attributes include its crystal clarity and avascularity in the health state. This normally transparent structure has been the focal point for Dr. Klintworth's research endeavors for more than two decades. This monograph summarizes current knowledge about angiogenesis within this tissue as well as information about the related issue of the cornea's normal avascularity. The text provides a comprehensive overview of the topic based on studies by a large number of investigators who were either concerned with corneal neovascularization in particular or angiogenesis in general.

Download or read book Issues in Ophthalmology and Optometry Research and Practice 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 2126 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Ophthalmology and Optometry Research and Practice: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Ophthalmology and Optometry Research and Practice. The editors have built Issues in Ophthalmology and Optometry Research and Practice: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Ophthalmology and Optometry Research and Practice in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Ophthalmology and Optometry Research and Practice: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book Novel Diagnostic Methods in Ophthalmology written by and published by BoD – Books on Demand. This book was released on 2019-09-04 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last 10 years, there has been huge progress in the general understanding of ocular disorders due to the availability and development of new in vivo imaging techniques, such as anterior and posterior eye segment optical coherence tomography as well as biochemical methods allowing rapid confirmation of clinical diagnosis.Introducing noninvasive diagnostic methods in ophthalmology led to an improvement in early differential diagnosis of conditions such as corneal dystrophies, dry eye disease, and various retinal and optic nerve diseases.Recent advances in diagnostic methods have also impacted the treatment methods. This book intends to provide the reader with a comprehensive overview of current ocular diagnostic methods, including the theoretical basis as well as practical approaches and usage in clinical practice.

Download or read book Surgery for the Dry Eye written by Gerd Geerling and published by Karger Medical and Scientific Publishers. This book was released on 2008-01-01 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: A number of structures contribute to tear production and maintenance, including the tear system, the lids and the orbit. The ocular surface itself is also a part of the system, including the cornea and conjunctiva. This makes for a very complex situation that can easily lead to changes in tear film and the ocular surface that are called "dry eye." Here a team of experts carefully examine how and when surgery is indicated, addressing normal tear film, normal anatomy (including immunological interactions), classification and diagnosis, anti-inflammatory and immnunosup-pressive concepts, correction and drainage techniques, surgery of the conjunctiva and cornea, keratoprosthesis surgery, botulism toxin injections, mucous membrane grafting, and salivary gland transplantation along with other treatments. The collection closed with a set of scientific studies. The color and monochrome clinical photographs and line illustrations are especially well-chosen and informative.

Download or read book Ocular Circulation and Neovascularization written by D. Benezra and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neovascularization isanormalphaseoftissue repair mechanlsm. In theeye, however, sproutingofnewvessels withinavasculartissuesandtheirgreatertendencytobleed havedetrimentaleffectsonvision. Diabeticretinopathy, corneal neovascularization, age-related macular degeneration, retinal veinocclusion, andretinopathy of prematurity are major causes of blindness. In all, uncontrolled proliferationofnewvesselsistheunderlying pathologicalcauseleadingtotheinexorablelossofvision. Development of lasertechnologiesandtheir wide use in ophthalmology have broughtsomehopeforthetreqtment of these diseases. However, itbecameevident that direct closureofthenewvesselsand/orablationoflargepartsof thetissuearenotidealsolutionstotheproblem. Recent advances in molecular biology and genetic engineering have fosteredbasic knowledge regarding the growth factors and intercellular messengers and their association with theproliferationofnew blood vessels. These latter findings sparked a renewed interest in Michaelson's "X-factor" ofocular neovascularization and opened avenues for possible innovative therapeutic approaches. Therefore, the suggestion to organize an international gathering of clinicians and scientists interested in problems of ocular circulation and neovascularization was received with great enthusiasm. Unanimously, it wasdecidedtodedicatethe symposium to Professor I.C. Michaelson, theinnovativescientist, the greatclinician, theindefatigableteacher, andaboveall, thewonderfulhumanbeing. The meeting was highlighted by the outstanding atmosphere of friendshipandscientif·ic exchanges. This book mirrors the information delivered and includes a selectionofpapersfromthescientificprogram. Theorganizationofthismeetingandthepublicationof thebookwouldnothavebeenpossiblewithouttheharmonious teameffortsmadebytheInternational, ScientificandLocal Committees. I am thankful tothe chairpersons of the varioussessionsfortheirtime, keeninterestandendeavor for the realizationofahighscientific level. I also deeplyacknowledgethehelpand & upportofArnallPatz, Bob Murphy, BertGlaser, RobertFrank, LarryHjelmeland, Gordon Klintworth, Neville Welsh, Charles Riva, Alec Garner, DesmondArcher, EphraimFriedman, MyronYanoff, MosheLahav, Willem Manschot, Hans-WaltherLarsenand Masanobu Uyama. The powerful stimulus of Hanan Zauberman, Steve Ryan, GabrielCoscas, GiselleSoubrane, MosheIvry, YuvalYassur and Sue and Peter Ballenwasmost instrumental in the realizationofthese"dreams". Asalways, Iwasfortunate tohavetheinvaluablecollaborationofmyloyalassistants: Evelyne Cohen, Genia Maftzir, Israel Barzel, Arieh Zelikovitch, andJudithBenEzra. Thesmoothrunningofthe meeting andtimelyeditingofthebookcouldnothave been possible without theincalculablehelp and indefatigable typing and councilofJudithFisher, whoseconded me in selectingthepapersandeditingthebook

Download or read book Pediatric Ophthalmology An Issue of Pediatric Clinics written by Mary Lou McGregor and published by Elsevier Health Sciences. This book was released on 2014-09-08 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the authors describe in this volume dedicated to vision in children, great strides have been made in recent years in preventing and identifying any loss of visual acuity, and, when identified, correcting it. The articles are written for the practicing pediatrician and describe conditions that are detected in pediatric practice and/or about which parents and patients may be knowledgeable and have questions. Articles in this issue are devoted to: Pediatric Refractive Surgery; The Lacrimal System; Periocular Hemangiomas and Lymphangiomas; Genetics and Ocular Disorders: A Focused Review; Retinopathy of Prematurity; Review of Pediatric Idiopathic Intracranial Hypertension; Allergic Eye Disease; and Convergence Insufficiency and Vision Therapy, to name a few.

Download or read book Anti VEGF written by Francesco Bandello and published by Karger Medical and Scientific Publishers. This book was released on 2010-01-01 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of therapy with anti-angiogenics or vascular endothelial growth factor inhibitors (anti-VEGF) has marked the beginning of a new era in neovascularization and macular edema treatment. Its main goals are the inhibition of growth and development of new vessels along with the reduction of vascular permeability. The advantages over conventional laser photocoagulation are evident as laser treatment always leaves scars and causes a retinal sensitivity deterioration. Starting with an outline of treatment principles, this volume covers all aspects of anti-VEGF therapy for ophthalmological disorders. In particular, specific chapters are dedicated to age-related macular degeneration, degenerative myopia, angioid streaks, inflammatory diseases, hereditary dystrophies, retinal vein occlusion, diabetic retinopathy, ocular tumors, as well as anterior segment neovascularization. The book gives an update on the application of anti-VEGF in ocular diseases to general ophthalmologists as well as retina specialists.

Download or read book Angiogenesis written by Michael E. Maragoudakis and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Angiogenesis is a multistep process, which involves activation, proliferation and directed migration of endothelial cells to form new capillaries from existing vessels. Under physiological conditions, in the adult organisms angiogenesis is extremely slow, yet it can be activated for a limited time only in situations such as ovulation or wound healing. In a number of disease states, however, there is a derangement of angiogenesis, which can contribute to the pathology of these conditions. Hence, understanding the molecular biology of endothelial cell activation and differentiation and the mechanisms involved in the regulation of angiogenesis, could explain the derangement in disease states and also provide the basis for developing promoters or suppressors of angiogenesis for clinical applications. This book contains the proceedings of the NATO Advanced Study Institute on "Angiogenesis: Molecular Biology, Oinical Aspects" held in Rhodes, Greece, from June 16-27, 1993. This meeting was a comprehensive review of the various aspects of angiogenesis such as embryonic development, endothelial cell heterogeneity and tissue specificity, molecular biology of endothelial cell, mechanisms for the regulation of angiogenesis, disease states in which angiogenesis is involved and potential application of promoters or suppressors of angiogenesis. The presentations and discussions of the meeting provided an opportunity for investigators from many different areas of basic science and medicine to exchange information, evaluate the present status and provide future research directions in the field of angiogenesis.

Download or read book Ophthalmology An Issue of Medical Clinics of North America E Book written by Nicholas J. Volpe and published by Elsevier Health Sciences. This book was released on 2021-05-14 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ophthalmology, An Issue of Medical Clinics of North America, E-Book

Download or read book Clinical Ophthalmic Oncology written by Arun D. Singh and published by Springer Science & Business Media. This book was released on 2013-11-26 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by internationally renowned experts, Clinical Ophthalmic Oncology provides practical guidance and advice on the diagnosis and management of the complete range of ocular cancers. The book supplies all of the state-of-the-art knowledge required in order to identify these cancers early and to treat them as effectively as possible. Using the information provided, readers will be able to provide effective patient care using the latest knowledge on all aspects of ophthalmic oncology, to verify diagnostic conclusions based on comparison with numerous full-color clinical photographs, and to locate required information quickly owing to the clinically focused and user-friendly format. This volume provides essential information on cancer epidemiology, etiology, pathology, angiogenesis, immunology, genetics, and staging systems and explains the principles underlying different therapeutic approaches.​

Download or read book Medical Retina written by Frank G Holz and published by Springer Science & Business Media. This book was released on 2010-03-18 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in ophthalmic imaging technology have revolutionized fundus examination and contributed significantly in elucidating the pathophysiology of retinal diseases and improving their diagnosis and treatment. It is therefore fitting that this detailed full-color textbook in the Medical Retina series is devoted to ocular imaging. The volume reviews in detail the role of both established and novel forms of imaging, and is designed to be of benefit to clinicians and researchers alike. All of the chapters have been written by internationally recognized experts at the forefront of their fields. The result is a comprehensive, state-of-the-art overview of retinal imaging that should prove informative and useful for everyone interested in the retina. Topics include: •Spectral domain optical coherence tomography (SD-OCT) of macular diseases •Comparison of OCT equipment •Simultaneous SD-OCT and confocal SLO imaging •Ultra-widefield imaging °Autofluorescence imaging •Near-infrared imaging •Macular pigment imaging •Metabolic mapping •Imaging of the choroid •Imaging the vitreous and the vitreoretinal interface with SD-OCT •New developments in OCT technology •Molecular imaging

Download or read book Edema New Insights for the Healthcare Professional 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-07-22 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edema: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Edema: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Edema: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.