Download or read book Naturally Occurring Phorbol Esters written by Evans and published by CRC Press. This book was released on 2018-01-18 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the topic of naturally occurring phorbol esters. Chapters include; environmental hazards of diterpene esters from plants, multi-stage carcinogenesis and the biological effects of tumor promoters, review of the family euphorbiaceae, biosynthetic and chemosystematic aspects of the euphorbiacea and thymelaeaceae, non-diterpenoid constituents of euphorbiacea, macrocyclic diterpenes of the family euphorbiacea, phorbol: its esters and derivatives, the daphnane polyol esters, the ingenane polyol esters, and the biochemical mechanism of action of phorbol ester.
Download or read book Naturally Occurring Phorbol Esters written by Evans and published by . This book was released on 2017 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book discusses the topic of naturally occurring phorbol esters. Chapters include; environmental hazards of diterpene esters from plants, multi-stage carcinogenesis and the biological effects of tumor promoters, review of the family euphorbiaceae, biosynthetic and chemosystematic aspects of the euphorbiacea and thymelaeaceae, non-diterpenoid constituents of euphorbiacea, macrocyclic diterpenes of the family euphorbiacea, phorbol: its esters and derivatives, the daphnane polyol esters, the ingenane polyol esters, and the biochemical mechanism of action of phorbol ester."--Provided by publisher.
Download or read book Naturally Occurring Phorbol Esters written by Evans FJ Ed and published by . This book was released on 1986 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Occurring Phorbol Esters Naturally written by Frederick J. Evans and published by . This book was released on 1986 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Naturally occuring phorbol esters written by Fred J. Evans and published by . This book was released on 1986 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Anticancer Drug Discovery and Development Natural Products and New Molecular Models written by Frederick A. Valeriote and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the publication of these proceedings from the Second Drug Discovery and Development Symposium, this forum has become the main mechanism for bringing together the principal groups involved in both discovering and developing new approaches to the treatment of cancer. This Second Symposium emphasized the types of materials being discovered and their therapeutic activity. This is especially evident in the natural product discovery programs, where unique and active structures are being identified. The major contributors to the meeting were the investigators participating in the National Cooperative (Natural Products) Drug Discovery Groups [NC(NP)DDG]. These groups reflect an association among researchers at universities or cancer centers, pharmaceutical companies and the National Cancer Institute. Their sources of materials are varied, reflecting chemical inventories of pharmaceutical companies, organic synthetic compounds from the laboratory, cytotoxics as well as biologics and their hybrids, and natural products obtained from plants, marine organisms and microorganisms. The models employed in the discovery systems vary from broadly cellular based to specific enzymes to defined cellular functions. Each of them is believed important to the malignant state and will allow for the discovery of compounds which will have efficacy in cancer therapy. The goal of the participants is both to discover new anticancer agents and to develop them as efficiently as possible into clinically useful additions to treatment. Of importance is the fact that there are a number of promising leads which will soon be moving into the clinic thereby testing the effectiveness of this NC (NP) DDG approach.
Download or read book Progress in the Chemistry of Organic Natural Products 102 written by A. Douglas Kinghorn and published by Springer. This book was released on 2016-07-05 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first contribution reviews the phytochemical, chemical, and biological literature on members of the ingenane class of diterpenoids from their first isolation in 1968 through 2015, highlighting unresolved issues both common to phorboids and specific to ingenol derivatives. The biogenesis of ingenol is discussed in the light of the Jakupovic proposal of a dissection between the formation of the macrocyclic Euphorbia diterpenoids and the phorboids, and the clinical development of ingenol mebutate is chronicled in the light of its “reverse-pharmacology” focus. The second contribution offers a comprehensive view of the chemical wealth and the taxonomic problems currently impeding chemical and biological investigations of the genus Laurencia. It addresses the botanical description and the growth and population dynamics of the genus, as well as its chemical diversity and ecological relations; the secondary metabolites as well as their sources of isolation; and finally the biological activity.
Download or read book The Poisoned Weed written by Donald G. Crosby and published by Oxford University Press. This book was released on 2004-04-01 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over-two thirds of the U.S. population is allergic to poison oak, poison ivy, or a related plant. These and many other common plants in our homes, fields, and gardens are irritants that cause misery to many. But surprisingly, there has never been a general guide to help raise awareness of them--and to help avoid them. This new book reviews the history, occurrence, classification, toxicity, and health aspects of all the major allergenic and irritant species.
Download or read book Poisonous Plant Contamination of Edible Plants written by Dr. Abdel-Fatta Rizk and published by CRC Press. This book was released on 1990-11-20 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Poisonous Plant Contamination of Edible Plants discusses the chemical and toxicological aspects of poisonous plants that frequently contaminate edible plants, such as grains and vegetables, thereby causing toxicity in humans. Topics covered include hepatotoxic plant contamination; cyanogenic plant contamination; contamination of edible plants by poisonous ones; chemical constituents; pharmacological and toxicological data; and the botanical characteristics of toxic plants. Botanists, food researchers, horticulturalists, and others interested in the contamination of edible plants by poisonous plants will find this book a valuable source of information.
Download or read book Studies on the Mechanism of Action of Phorbol Esters in Skin Tumor Formation written by William McKenzie Baird and published by . This book was released on 1971 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Fortschritte der Chemie organischer Naturstoffe Progress in the Chemistry of Organic Natural Products written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Environmental Impact of Biofuels written by Marco Aurelio Dos Santos Bernardes and published by BoD – Books on Demand. This book was released on 2011-09-06 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aspires to be a comprehensive summary of current biofuels issues and thereby contribute to the understanding of this important topic. Readers will find themes including biofuels development efforts, their implications for the food industry, current and future biofuels crops, the successful Brazilian ethanol program, insights of the first, second, third and fourth biofuel generations, advanced biofuel production techniques, related waste treatment, emissions and environmental impacts, water consumption, produced allergens and toxins. Additionally, the biofuel policy discussion is expected to be continuing in the foreseeable future and the reading of the biofuels features dealt with in this book, are recommended for anyone interested in understanding this diverse and developing theme.
Download or read book Alicyclic Compounds written by Malcolm Sainsbury and published by Elsevier. This book was released on 2016-06-06 with total page 667 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rodd's Chemistry of Carbon Compounds, Volume II: Alicyclic Compounds focuses on alicyclic chemistry. The book first ponders on acyclic and monocyclic monoterpenoids, including artemisyl, santolinyl, chrysanthemyl, and other irregular systems; naturally occurring halogenated monoterpenoids; cyclobutanes; and tetramethylcyclohexanes. The text discusses the carotenoid group of natural products. Trends in carotenoid chemical research; improved methodology; optical isomerism including aliene isomerism; and geometrical isomerism are described. The book discusses cycloheptanes and cyclooctanes, large alicyclic ring systems, and polycarbonic compounds with separate ring systems and spiro compounds. The text describes polycyclic compounds and polycarbocyclic bridged ring compounds, and then discusses bicarbocyclic natural products. The Wagner-Meerwein rearrangement; camphor and related compounds; fenchone and related compounds; and carane, thujane, and pinane groups are also considered. The text is a valuable reference for readers interested in the study of carbon compounds.
Download or read book Carcinogenesis Fundamental Mechanisms and Environmental Effects written by A. Pullman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the 13th Jerusalem Symposium on Quantum Chemistry and Biochemistry held in Jerusalem, Israel, April 28-May 2, 1980
Download or read book Textbook of Contact Dermatitis written by Richard J.G. Rycroft and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt: 10. 1. 1. 1 The Purpose of Patch Testing Patch testing is a well-established method of diagnosing allergic contact dermatitis, a delayed type of hypersensitivity (type IV reaction). Patients with a history and clinical picture of contact dermatitis are reexposed to the suspected allergens under controlled conditions to verify the diagnosis. Besides testing patients with hand, arm, face or leg eczema (stasis dermatitis), testing of other types of eczema (atopic, seborrhoeic dermatitis, nummular eczema) is sometimes indicated, especially when the dermatologist suspects contact allergy to prescribed topical medicaments and their vehicles. Apart from its use to confirm a suspected allergic contact dermatitis, the patch test procedure can also be used before recommending alternative corti costeroids, skin care products, cosmetics, gloves, etc. in a particular patient. If the patient does not react to the alternatives tested, it is very unlikely that she or he will react to the products in ordinary use. 10. 1. 1.2 Standardization The first patch tests according to present principles were carried out in 1895 [1], but were preceded by some preliminary experiments [2] (see Chap. 1).
Download or read book Natural Poisons and Venoms written by Eberhard Teuscher and published by Walter de Gruyter GmbH & Co KG. This book was released on 2023-06-06 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biogenic toxins are fascinating natural products characterized by an enormous diversity of chemical structures and pharmacological activities. They not only pose hazards to humans and animals, but they are important components in the interplay of substances and living beings in nature and, moreover, important sources for new drugs. The present book is the first volume of the 5-volume series "Natural Poisons and Venoms". Volumes 1-3 cover poisons produced by plants, volume 4 summarizes poisons and venoms of animals and volume 5 deal with poisons of fungi, cyanobacteria, and other microorganisms. This volume starts with a fundamental chapter on history, chemistry and pharmacology of natural toxins, importance of the toxins for their producer, potential danger for humans and animals, and general aspects of toxicology including notes for first aid and proposals for clinical measures. The following chapters focus on the poisonous representatives of terpenes and the related steroids. The reader will be informed about the botany and occurrence of plants producing these toxins, the chemistry, the biogenesis and the pharmacology of the toxins, possible causes of poisonings, precautions to avoid poisonings, symptoms of poisonings of humans and animals, proposals for treatment measures and the possible usefulness, in the past, in present and in the future, of these toxins, especially for the development of new medicines. Numerous images of plants and chemical structural formulas complete the book. Extensive lists of literature references are given. The handbook is intended for physicians, veterinarians, pharmacists, chemists, biochemists, food chemists and biologists, for the students in the relevant fields, and also for interested laymen. You will be informed about all aspects of natural toxins based on the latest knowledge.
Download or read book Bibliography of Agriculture written by and published by . This book was released on 1991-04 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt:
