Download or read book O Pr ximo N vel de Investimento em Criptomoedas written by Wayne Walker and published by Wayne Walker. This book was released on 2021-06-11 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: No livro O Próximo Nível de Investimento em Criptomoedas, o aclamado autor de investimentos Wayne Walker oferece estratégias de investimento avançadas e poderosas para Ether, Bitcoin e outras criptomoedas. Este livro é para aqueles que sabem além do básico e estão prontos para aprender sobre o gerenciamento de risco do próximo nível para seu portfólio de criptomoedas existente ou futuro. Você será exposto a técnicas exclusivas, comprovadas e lucrativas de alocação de ativos. Ao final do livro, você estará entre os investidores de cripto mais informados e atualizados. Você obterá as técnicas mais atualizadas: - Como montar e executar um portfólio como um profissional - Técnicas de negociação de alta probabilidade - Usar as informações das exchanges de cripto a seu favor - Você aprenderá gerenciamento de risco avançado e muito mais

Download or read book Bitcoin Criptomoedas written by Ivan Schroll and published by Ivan Schroll. This book was released on 2024-01-26 with total page 45 pages. Available in PDF, EPUB and Kindle. Book excerpt: Em "Bitcoin & Criptomoedas: O Guia Definitivo para Iniciantes", o autor Ivan Schroll desvenda os segredos do dinheiro digital com clareza e precisão, transformando iniciantes em participantes informados do mundo das criptomoedas. Se você está buscando entender o funcionamento do Bitcoin, as nuances das altcoins e como mergulhar com segurança no investimento online, este livro é sua ferramenta essencial. Com linguagem acessível e exemplos práticos, Schroll não só ensina os fundamentos do mercado de criptomoedas e as estratégias de investimento, mas também guia você através da complexa tecnologia blockchain. Este guia abrangente é enriquecido com insights valiosos e dicas práticas, capacitando você a tomar decisões de investimento confiantes e seguras. "Bitcoin & Criptomoedas" não é apenas um livro – é uma bússola para navegar na inovação financeira que está redefinindo o futuro do dinheiro. Faça parte da transformação hoje mesmo e leve seu conhecimento financeiro para o próximo nível com o poder das criptomoedas.

Download or read book Translational Medicine written by Joy A. Cavagnaro and published by CRC Press. This book was released on 2021-11-26 with total page 952 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.

Download or read book Preclinical Safety Evaluation of Biopharmaceuticals written by Joy A. Cavagnaro and published by John Wiley & Sons. This book was released on 2013-03-07 with total page 1012 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The goal is to provide a comprehensive reference book for the preclinicaldiscovery and development scientist whose responsibilities span target identification, lead candidate selection, pharmacokinetics, pharmacology, and toxicology, and for regulatory scientists whose responsibilities include the evaluation of novel therapies." —From the Afterword by Anthony D. Dayan Proper preclinical safety evaluation can improve the predictive value, lessen the time and cost of launching new biopharmaceuticals, and speed potentially lifesaving drugs to market. This guide covers topics ranging from lead candidate selection to establishing proof of concept and toxicity testing to the selection of the first human doses. With chapters contributed by experts in their specific areas, Preclinical Safety Evaluation of Biopharmaceuticals: A Science-Based Approach to Facilitating Clinical Trials: Includes an overview of biopharmaceuticals with information on regulation and methods of production Discusses the principles of ICH S6 and their implementation in the U.S., Europe, and Japan Covers current practices in preclinical development and includes a comparison of safety assessments for small molecules with those for biopharmaceuticals Addresses all aspects of the preclinical evaluation process, including: the selection of relevant species; safety/toxicity endpoints; specific considerations based upon class; and practical considerations in the design, implementation, and analysis of biopharmaceuticals Covers transitioning from preclinical development to clinical trials This is a hands-on, straightforward reference for professionals involved in preclinical drug development, including scientists, toxicologists, project managers, consultants, and regulatory personnel.

Download or read book Blockchain written by Melanie Swan and published by "O'Reilly Media, Inc.". This book was released on 2015-01-24 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bitcoin is starting to come into its own as a digital currency, but the blockchain technology behind it could prove to be much more significant. This book takes you beyond the currency ("Blockchain 1.0") and smart contracts ("Blockchain 2.0") to demonstrate how the blockchain is in position to become the fifth disruptive computing paradigm after mainframes, PCs, the Internet, and mobile/social networking. Author Melanie Swan, Founder of the Institute for Blockchain Studies, explains that the blockchain is essentially a public ledger with potential as a worldwide, decentralized record for the registration, inventory, and transfer of all assets—not just finances, but property and intangible assets such as votes, software, health data, and ideas. Topics include: Concepts, features, and functionality of Bitcoin and the blockchain Using the blockchain for automated tracking of all digital endeavors Enabling censorship?resistant organizational models Creating a decentralized digital repository to verify identity Possibility of cheaper, more efficient services traditionally provided by nations Blockchain for science: making better use of the data-mining network Personal health record storage, including access to one’s own genomic data Open access academic publishing on the blockchain This book is part of an ongoing O’Reilly series. Mastering Bitcoin: Unlocking Digital Crypto-Currencies introduces Bitcoin and describes the technology behind Bitcoin and the blockchain. Blockchain: Blueprint for a New Economy considers theoretical, philosophical, and societal impact of cryptocurrencies and blockchain technologies.

Download or read book Heteromation and Other Stories of Computing and Capitalism written by Hamid R. Ekbia and published by MIT Press. This book was released on 2017-05-04 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: An exploration of a new division of labor between machines and humans, in which people provide value to the economy with little or no compensation. The computerization of the economy—and everyday life—has transformed the division of labor between humans and machines, shifting many people into work that is hidden, poorly compensated, or accepted as part of being a “user” of digital technology. Through our clicks and swipes, logins and profiles, emails and posts, we are, more or less willingly, participating in digital activities that yield economic value to others but little or no return to us. Hamid Ekbia and Bonnie Nardi call this kind of participation—the extraction of economic value from low-cost or free labor in computer-mediated networks—“heteromation.” In this book, they explore the social and technological processes through which economic value is extracted from digitally mediated work, the nature of the value created, and what prompts people to participate in the process. Arguing that heteromation is a new logic of capital accumulation, Ekbia and Nardi consider different kinds of heteromated labor: communicative labor, seen in user-generated content on social media; cognitive labor, including microwork and self-service; creative labor, from gaming environments to literary productions; emotional labor, often hidden within paid jobs; and organizing labor, made up of collaborative groups such as citizen scientists. Ekbia and Nardi then offer a utopian vision: heteromation refigured to bring end users more fully into the prosperity of capitalism.

Download or read book David Hammons written by Elena Filipovic and published by MIT Press. This book was released on 2017-09-08 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing on unpublished documents and oral histories, an illustrated examination of an iconic artwork of an artist who has made a lifework of tactical evasion. One wintry day in 1983, alongside other street sellers in the East Village, David Hammons peddled snowballs of various sizes. He had neatly laid them out in graduated rows and spent the day acting as obliging salesman. He called the evanescent and unannounced street action Bliz-aard Ball Sale, thus inscribing it into a body of work that, from the late 1960s to the present, has used a lexicon of ephemeral actions and self-consciously “black" materials to comment on the nature of the artwork, the art world, and race in America. And although Bliz-aard Ball Sale has been frequently cited and is increasingly influential, it has long been known only through a mix of eyewitness rumors and a handful of photographs. Its details were as elusive as the artist himself; even its exact date was unrecorded. Like so much of the artist's work, it was conceived, it seems, to slip between our fingers—to trouble the grasp of the market, as much as of history and knowability. In this engaging study, Elena Filipovic collects a vast oral history of the ephemeral action, uncovering rare images and documents, and giving us singular insight into an artist who made an art of making himself difficult to find. And through it, she reveals Bliz-aard Ball Sale to be the backbone of a radical artistic oeuvre that transforms such notions as “art,” “commodity,” “performance,” and even “race” into categories that shift and dissolve, much like slowly melting snowballs.

Download or read book The Rise of Digital Money written by Mr.Tobias Adrian and published by International Monetary Fund. This book was released on 2019-07-15 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: This paper marks the launch of a new IMF series, Fintech Notes. Building on years of IMF staff work, it will explore pressing topics in the digital economy and be issued periodically. The series will carry work by IMF staff and will seek to provide insight into the intersection of technology and the global economy. The Rise of Digital Money analyses how technology companies are stepping up competition to large banks and credit card companies. Digital forms of money are increasingly in the wallets of consumers as well as in the minds of policymakers. Cash and bank deposits are battling with so-called e-money, electronically stored monetary value denominated in, and pegged to, a currency like the euro or the dollar. This paper identifies the benefits and risks and highlights regulatory issues that are likely to emerge with a broader adoption of stablecoins. The paper also highlights the risks associated with e-money: potential creation of new monopolies; threats to weaker currencies; concerns about consumer protection and financial stability; and the risk of fostering illegal activities, among others.

Download or read book Routledge Handbook of Latin American Security written by David R. Mares and published by Routledge. This book was released on 2015-07-16 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new Handbook is a comprehensive collection of cutting-edge essays on all aspects of Latin American Security by a mix of established and emerging scholars. The Routledge Handbook of Latin American Security identifies the key contemporary topics of research and debate, taking into account that the study of Latin America’s comparative and international politics has undergone dramatic changes since the end of the Cold War, the return of democracy and the re-legitimization and re-armament of the military against the background of low-level uses of force short of war. Latin America’s security issues have become an important topic in international relations and Latin American studies. This Handbook sets a rigorous agenda for future research and is organised into five key parts: • The Evolution of Security in Latin America • Theoretical Approaches to Security in Latin America • Different 'Securities' • Contemporary Regional Security Challenges • Latin America and Contemporary International Security Challenges With a focus on contemporary challenges and the failures of regional institutions to eliminate the threat of the use of force among Latin Americans, this Handbook will be of great interest to students of Latin American politics, security studies, war and conflict studies and International Relations in general.

Download or read book Helen Chadwick written by Marina Warner and published by MIT Press. This book was released on 2022-09-13 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: An illustrated exploration of Helen Chadwick’s erotic, playful, and fierce 1986 installation. In 1986 the Institute of Contemporary Arts in London showed a new commission by the artist Helen Chadwick (1954–1996). What Chadwick conceived for the ICA exhibition explored her characteristic themes—the female body (her own), the aesthetics of pleasure, the material variety and wonder of phenomena—but took them in a new, flamboyant direction. In this illustrated volume, Marina Warner examines one part of Chadwick’s installation, The Oval Court. This work was erotic, playful, and fierce; it showed imaginative ambition on an exceptional scale and a unique, piquant sensibility, both raunchy and delicate. Despite the work’s recognition as a feminist monument of rare intensity, it has rarely been shown or discussed since the author’s catalogue essay for the original exhibition. Warner here reconsiders Chadwick’s influence as an artist who helped to shift conventional aesthetics and transvalue despised, even abominated forms. Exploring the work’s richly layered composition in light of intervening years, Warner shows how Chadwick’s imagination has shaped many artists’ ideas and ethics, and emboldened their adventures with materials.

Download or read book Cryptoassets written by Chris Brummer and published by Oxford University Press. This book was released on 2019-09-12 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cryptoassets represent one of the most high profile financial products in the world, and fastest growing financial products in history. From Bitcoin, Etherium and Ripple's XRP-so called "utility tokens" used to access financial services-to initial coin offerings that in 2017 rivalled venture capital in money raised for startups, with an estimated $5.6 billion (USD) raised worldwide across 435 ICOs. All the while, technologists have hailed the underlying blockchain technology for these assets as potentially game changing applications for financial payments and record-keeping. At the same time, cryptoassets have produced considerable controversy. Many have turned out to be lacklustre investments for investors. Others, especially ICOs, have also attracted noticeable fraud, failing firms, and alarming lapses in information-sharing with investors. Consequently, many commentators around the world have pressed that ICO tokens be considered securities, and that concomitant registration and disclosure requirements attach to their sales to the public. This volume assembles an impressive group of scholars, businesspersons and regulators to collectively write on cryptoassets. This volume represents perspectives from across the regulatory ecosystem, and includes technologists, venture capitalists, scholars, and practitioners in securities law and central banking.

Download or read book Beverly Buchanan written by Amelia Groom and published by MIT Press. This book was released on 2021-02-02 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: An illustrated examination of Beverly Buchanan's 1981 environmental sculpture, which exists in an ongoing state of ruination. Beverly Buchanan's Marsh Ruins (1981) are large, solid mounds of cement and shell-based tabby concrete, yet their presence has always been elusive. Hiding in the tall grasses and brackish waters of the Marshes of Glynn, on the southeast coast of Georgia, the Marsh Ruins merge with their surroundings as they enact a curious and delicate tension between destruction and endurance. This volume offers an illustrated examination of Buchanan's environmental sculpture, which exists in an ongoing state of ruination.

Download or read book Lee Lozano written by Sarah Lehrer-Graiwer and published by MIT Press. This book was released on 2014-02-28 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: An examination of Lee Lozano's greatest experiment in art and endurance—a major work of art that might not exist at all. The artist Lee Lozano (1930–1999) began her career as a painter; her work rapidly evolved from figuration to abstraction. In the late 1960s, she created a major series of eleven monochromatic Wave paintings, her last in the medium. Despite her achievements as a painter, Lozano is best known for two acts of refusal, both of which she undertook as artworks: Untitled (General Strike Piece), begun in 1969, in which she cut herself off from the commercial art world for a time; and the so-called Boycott Piece, which began in 1971 as a month-long experiment intended to improve communication but became a permanent hiatus from speaking to or directly interacting with women. In this book, Sarah Lehrer-Graiwer examines Lozano's Dropout Piece, the culmination of her practice, her greatest experiment in art and endurance, encompassing all her withdrawals, and ending only with her burial in an unmarked grave. And yet, although Dropout Piece is among Lozano's most important works, it might not exist at all. There is no conventional artwork to be exhibited, no performance event to be documented. Lehrer-Graiwer views Dropout Piece as leveraging the artist's entire practice and embodying her creative intelligence, her radicality, and her intensity. Combining art history, analytical inquiry, and journalistic investigation, Lehrer-Graiwer examines not only Lozano's act of dropping out but also the evolution over time of Dropout Piece in the context of the artist's practice in New York and her subsequent life in Dallas.

Download or read book Donald Rodney written by Richard Birkett and published by MIT Press. This book was released on 2023-05-30 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: An illustrated examination of Donald Rodney’s seminal digital media work Autoicon (1997–2000). Donald Rodney's Autoicon, a work originally produced as both a website and CD-ROM, was conceived by the artist in the mid-1990s but not completed until two years after his death in 1998. Referencing Jeremy Bentham’s infamous nineteenth-century "Auto-Icon," the work proposes an extension of the personhood and presence of Rodney, while critically challenging dominant conceptions of the self, the body, and historicity. Grounded in a partial collection of medical documents that constitute biomedicine’s attempts to comprehensively "know" and maintain Rodney’s body during his lifelong experience of sickle-cell aneamia, Autoicon pursues the artist’s address, from the mid-1980s onward, of the British social and institutional body’s cellular composition through racialized, biopolitical power. Autoicon consists of a Java-based AI and neural network that engages the user in text-based "chat," and provides responses by drawing from a dense body of "data points" related to Rodney and his work, including documentation of artworks, medical records, interviews, images, notes, and video. Pulling both from this internal archive and the external archive of the Internet, a "montage machine" composes constantly mutating images according to a rule-based system established around Rodney’s working process. In this One Work edition, curator Richard Birkett traces the distinct contemporary presence of Autoicon, and the ideas and relations that emerged around its conception before and after Rodney’s death, particularly linking the work to the artist’s seminal 1997 exhibition 9 Night in Eldorado. Birkett addresses Autoicon as both an index of entangled social and material relations around Rodney—a form of dispersed memory—and a vector of critical creative production that continues to resonate with contemporary artistic practices and radical thought. While attuned to late twentieth century discourse around the body’s dissolution into the "virtual" and the technological potential for extending consciousness, in its content and structure Autoicon locates these discourses of the human and posthuman in relation to the durable productive forces of post-Enlightenment racialization and ableism. The workings of the mind that Autoicon presents are intrinsically tied to Rodney’s wider use in his work of bodily matter, and genealogically bound to a Black history of displacement, dispossession, and resistance experienced physiologically, socially, and familially by the artist. Autoicon offers up a counter-manifestation of the subject as formed and multiplied through temporal disjuncture, affectability and acts of preservation, care, and collectivity.

Download or read book Bitcoin written by Jerry Brito and published by Mercatus Center at George Mason University. This book was released on 2013-12-19 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the world’s first decentralized digital currency, Bitcoin has the potential to revolutionize online payments systems in a way that benefits consumers and businesses. Instead of using an intermediary such as PayPal or submitting credit card information to a third party for verification—both of which often include transaction fees and other restrictions—Bitcoin allows individuals to pay each other directly for goods or services. The characteristics that make Bitcoin so innovative have also made it a target for regulators, who fear that the cryptocurrency will aid tax evasion, money laundering, and other crimes. While it is true that it can be used for nefarious purposes, the same can be said of cash. But, unlike cash, Bitcoin transactions are recorded in an online ledger. In this new primer published by the Mercatus Center at George Mason University, Jerry Brito and Andrea Castillo describe how the digital currency works and address many of the common misconceptions about it. They also analyze current laws and regulations that may already cover digital currencies and warn against preemptively placing regulatory restrictions on Bitcoin that could stifle the new technology before it has a chance to evolve. In addition, they give several recommendations about how to treat Bitcoin going forward. Here, at the forefront of the debate, Brito and Castillo both support innovation and provide much-needed clarity for policymakers and law enforcement. A Spanish edition of this book is also available from the Mercatus Center.

Download or read book Introduction to Operations Research written by Frederick S. Hillier and published by McGraw-Hill Science, Engineering & Mathematics. This book was released on 1995 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Disk contains: OR Courseware to accompany text, featuring demostration examples, interactive routines, and automatic routines.

Download or read book Philip Guston written by Craig Burnett and published by MIT Press. This book was released on 2014-02-28 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: An illustrated examination of Philip Guston's comic and complex painting The Studio. Throughout his career, Philip Guston's work metamorphosed from figural to abstract and back to figural. In the 1950s, Guston (1913–1980) produced a body of shimmering abstract paintings that made him—along with Willem de Kooning, Jackson Pollock, and Franz Kline—an influential abstract expressionist of the “gestural” tendency. In the late 1960s, with works like The Studio came his most radical shift. Drawing from the imagery of his early murals and from elements in his later drawings, ignoring the prevailing “coolness” of Minimalism and antiform abstraction, Guston invented for these late works a cast of cartoon-like characters to articulate a vision that was at once comic, crude, and complex. In The Studio, Guston offers a darkly comic portrait of the artist as a hooded Ku Klux Klansman, painting a self-portrait. In this concise and generously illustrated book, Craig Burnett examines The Studio in detail. He describes the historical and personal motivations for Guston's return to figuration and the (mostly negative) critical reaction to the work from Hilton Kramer and others. He looks closely at the structure of The Studio, and at the influence of Piero della Francesca, Manet, and Krazy Kat, among others; and he considers the importance of the column of smoke in the painting—as a compositional device and as a ghost of abstraction and metaphysics. The Studio signals not only Guston's own artistic evolution but a broader shift, from the medium-centric and teleological claim of modernism to the discursive, carnivalesque, and mucky world of postmodernism.