Download or read book Nutrition and biomarkers in psychiatry research on micronutrient deficiencies in schizophrenia the role of the intestine in the hyperserotonemia of autism and a method for non hypothesis driven discovery of biomarkers in urine written by Ramses Franciscus Jacobus Kemperman and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neurological Psychiatric and Developmental Disorders written by Institute of Medicine and published by National Academies Press. This book was released on 2001-01-01 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain disordersâ€"neurological, psychiatric, and developmentalâ€"now affect at least 250 million people in the developing world, and this number is expected to rise as life expectancy increases. Yet public and private health systems in developing countries have paid relatively little attention to brain disorders. The negative attitudes, prejudice, and stigma that often surround many of these disorders have contributed to this neglect. Lacking proper diagnosis and treatment, millions of individual lives are lost to disability and death. Such conditions exact both personal and economic costs on families, communities, and nations. The report describes the causes and risk factors associated with brain disorders. It focuses on six representative brain disorders that are prevalent in developing countries: developmental disabilities, epilepsy, schizophrenia, bipolar disorder, depression, and stroke. The report makes detailed recommendations of ways to reduce the toll exacted by these six disorders. In broader strokes, the report also proposes six major strategies toward reducing the overall burden of brain disorders in the developing world.
Download or read book Diet Microbe Interactions in the Gut written by Kieran Tuohy and published by Academic Press. This book was released on 2014-08-04 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing on expert opinions from the fields of nutrition, gut microbiology, mammalian physiology, and immunology, Diet-Microbe Interactions for Human Health investigates the evidence for a unified disease mechanism working through the gut and its resident microbiota, and linking many inflammation-related chronic diet associated diseases. State of the art post-genomic studies can highlight the important role played by our resident intestinal microbiota in determining human health and disease. Many chronic human diseases associated with modern lifestyles and diets — including those localized to the intestinal tract like inflammatory bowel disease and celiac disease, and more pervasive systemic conditions such as obesity, diabetes and cardiovascular disease — are characterized by aberrant profiles of gut bacteria or their metabolites. Many of these diseases have an inflammatory basis, often presenting with a chronic low-grade systemic inflammation, hinting at persistent and inappropriate activation of inflammatory pathways. Through the presentation and analysis of recent nutrition studies, this book discusses the possible mechanisms underpinning the disease processes associated with these pathologies, with high fat diets appearing to predispose to disease, and biologically active plant components, mainly fiber and polyphenols, appearing to reduce the risk of chronic disease development. One comprehensive, translational source for all aspects of nutrition and diet's effect on gastrointestinal health and disease Experts in nutrition, diet, microbiology and immunology take readers from the bench research (cellular and biochemical mechanisms of vitamins and nutrients) to new preventive and therapeutic approaches Clear presentations by leading researchers of the cellular mechanisms underlying diet, immune response, and gastrointestinal disease help practicing nutritionists and clinicians (gastroenterologists, endocrinologists) map out new areas for clinical research and structuring clinical recommendations
Download or read book Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders written by Paul C. Guest and published by Springer. This book was released on 2019-02-12 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book includes a series of reviews on general aspects of biomarker use in the study of psychiatric and neurodegenerative diseases and the development of medications involved in their treatment. It describes the pros and cons of the various approaches and covers the successes and failures in this research field. It is only by a thorough understanding of the shortcomings that progress can be made. The overall goal is to facilitate the understanding and treatment of these disorders, by providing a viable mechanism of catching up with other areas of modern medicine, such as diabetes and heart disease. Finally, it is anticipated that the development and application of valid biomarker tests and the leveraging of novel drug targets will help the fields of psychiatry on neurodegenerative disorders move into the area of personalized medicine where the right patients can receive the right medication at the right time for the best possible outcome.
Download or read book Clinical Manual for the Treatment of Autism written by Eric Hollander and published by American Psychiatric Pub. This book was released on 2007 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explaining how to diagnose autism by providing examples and guidelines for evaluation and testing of individuals, this guide helps practitioners to evaluate the appropriate role of various medications for specific target symptoms and individuals. It also describes complementary and alternative therapies and explores promising new avenues of treatment.
Download or read book Serotonin Dopamine Interaction Experimental Evidence and Therapeutic Relevance written by Giuseppe Di Giovanni and published by Elsevier. This book was released on 2008-11-11 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a unique and timely multidisciplinary synthesis of our current knowledge of the anatomy, pharmacology, physiology and behavioral data of the serotonin (5-HT)-dopamine (DA) interactions. Central serotonergic and dopaminergic systems play a critical role in the regulation of normal and abnormal behaviors. Moreover, recent evidence suggests that the dysfunction of the DA and 5-HT neurotransmitter systems contribute to various mental disorders including depression, schizophrenia, drug addiction and Parkinson's disease. This extremely important topic is of wide interest within the scientific community, with relevance not only to specialists but also to general practitioners and students. The book provides a valuable contribution to the debate on new pharmacological approaches for several psychopathological states, with contributions from expert neuroscientists and pharmacologists who comprehensively survey the most significant currently active areas of dopamine/serotonin interactions. * Provides an understanding of the interaction between Serotonin and Dopamine. * Appeals equally to specialists, general practitioners, students and researchers. * Contributes to the debate on new pharmacological approaches to several psychopathological states * Gives a comprehensive anatomical description plus the physiology and pharmacology of dopaminergic and serotonergic systems * Singles out neuropsychiatric and suggests new therapeutic approaches.
Download or read book It Ain t Necessarily So written by Richard Lewontin and published by New York Review of Books. This book was released on 2001-09-30 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Is our nature—as individuals, as a species—determined by our evolution and encoded in our genes? If we unravel the protein sequences of our DNA, will we gain the power to cure all of our physiological and psychological afflictions and even to solve the problems of our society? Today biologists—especially geneticists—are proposing answers to questions that have long been asked by philosophy or faith or the social sciences. Their work carries the weight of scientific authority and attracts widespread public attention, but it is often based on what the renowned evolutionary biologist Richard Lewontin identifies as a highly reductive misconception: "the pervasive error that confuses the genetic state of an organism with its total physical and psychic nature as a human being." In these nine essays covering the history of modern biology from Darwin to Dolly the sheep, all of which were originally published in The New York Review of Books, Lewontin combines sharp criticisms of overreaching scientific claims with lucid expositions of the exact state of current scientific knowledge—not only what we do know, but what we don't and maybe won't anytime soon. Among the subjects he discusses are heredity and natural selection, evolutionary psychology and altruism, nineteenth-century naturalist novels, sex surveys, cloning, and the Human Genome Project. In each case he casts an ever-vigilant and deflationary eye on the temptation to look to biology for explanations of everything we want to know about our physical, mental, and social lives. These essays—several of them updated with epilogues that take account of scientific developments since they were first written—are an indispensable guide to the most controversial issues in the life sciences today. The second edition of this collection includes new essays on genetically modified food and the completion of the Human Genome Project. It is an indispensable guide to the most controversial issues in the life sciences today.
Download or read book The Biology of the Autistic Syndromes written by Christopher Gillberg and published by Mac Keith Press. This book was released on 1992-01-01 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this major reference work the authors give a complete account of what is currently known about autism, which will be an invaluable source book to all clinicians who interact with autistic patients. In the first parts, the book describes and reviews the clinical considerations and also reviews the general literature, including genetical studies and brain imaging. Part III reviews other disease states that possess a subgroup showing autistic syndromes and Part IV gives an account of treatments of autism currently under investigation.
Download or read book Gut Microbiome and Behavior written by and published by Academic Press. This book was released on 2016-10-25 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gut Microbiome and Behavior, the latest volume in the International Review of Neurobiology series, provides a comprehensive overview of the gut microbiome on the brain and behavior, fully encapsulating the latest research in the field and defining the scope of this influence to outline potential mechanisms and possible implications. Contains the expertise of contributors in the field who discuss the gut microbiome and its effect on the brain and behavior Defines the scope of the influence of the gut microbiome and the potential mechanisms and implications Charts the way forward in this frontier area of research
Download or read book Histamine in the brain written by Jian-Sheng Lin and published by Frontiers Media SA. This book was released on 2015-03-18 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain aminergic pathways are organized in parallel and interacting systems, which support a range of functions, from homoeostatic regulations to cognitive, and motivational processes. Despite overlapping functional influences, dopamine, serotonin, noradrenaline and histamine systems provide different contributions to these processes. The histaminergic system, long ignored as a major regulator of the sleep-wake cycle, has now been fully acknowledged also as a major coordinator of attention, learning and memory, decision making. Although histaminergic neurons project widely to the whole brain, they are functionally heterogeneous, a feature which may provide the substrate for differential regulation, in a region-specific manner, of other neurotransmitter systems. Neurochemical preclinical studies have clearly shown that histamine interacts and modulates the release of neurotransmitters that are recognized as major modulators of cognitive processing and motivated behaviours. As a consequence, the histamine system has been proposed as a therapeutic target to treat sleep-wake disorders and cognitive dysfunctions that accompany neurodegenerative and neuroinflammatory pathologies. Last decades have witnessed an unexpected explosion of interest in brain histamine system, as new receptors have been discovered and selective ligands synthesised. Nevertheless, the complete picture of the histamine systems fine-tuning and its orchestration with other pathways remains rather elusive. This Research Topic is intended to offer an inter-disciplinary forum that will improve our current understanding of the role of brain histamine and provide the fundamentals necessary to drive innovation in clinical practice and to improve the management and treatment of neurological disorders.
Download or read book Psychoneuroimmunology written by Qing Yan and published by Humana Press. This book was released on 2012-08-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychoneuroimmunology (PNI) has developed rapidly in the last four decades. As a multidisciplinary area, PNI may provide a scientific basis for mind-body relationships toward the development of personalized and systems medicine. In Psychoneuroimmunology:Methods and Protocols, expert researchers in the field detail methods and protocols geared toward the development of integrative and individualized therapeutics in multiple dimensions from drugs to behaviors. Written in the highly successful Methods in Molecular BiologyTM series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Psychoneuroimmunology:Methods and Protocols aids scientists in continuing to study holistic views for the translation of psychoneuroimmunology into better preventive and personalized medical practice.
Download or read book The Autistic Syndromes written by Mary Coleman and published by North-Holland. This book was released on 1976 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Defending Life written by Francis J. Beckwith and published by Cambridge University Press. This book was released on 2007-08-13 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Defending Life is arguably the most comprehensive defense of the pro-life position on abortion - morally, legally, and politically - that has ever been published in an academic monograph. It offers a detailed and critical analysis of Roe v. Wade and Planned Parenthood v. Casey as well as arguments by those who defend a Rawlsian case for abortion-choice, such as J. J. Thomson. The author defends the substance view of persons as the view with the most explanatory power. The substance view entails that the unborn is a subject of moral rights from conception. While defending this view, the author responds to the arguments of thinkers such as Boonin, Dworkin, Stretton, Ford and Brody. He also critiques Thomson's famous violinist argument and its revisions by Boonin and McDonagh. Defending Life includes chapters critiquing arguments found in popular politics and the controversy over cloning and stem cell research.
Download or read book Phylogenetic Diversity written by Rosa A. Scherson and published by Springer. This book was released on 2018-08-31 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Biodiversity” refers to the variety of life. It is now agreed that there is a “biodiversity crisis”, corresponding to extinction rates of species that may be 1000 times what is thought to be “normal”. Biodiversity science has a higher profile than ever, with the new Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services involving more than 120 countries and 1000s of scientists. At the same time, the discipline is re-evaluating its foundations – including its philosophy and even core definitions. The value of biodiversity is being debated. In this context, the tree of life (“phylogeny”) is emerging as an important way to look at biodiversity, with relevance cutting across current areas of concern – from the question of resilience within ecosystems, to conservation priorities for globally threatened species – while capturing the values of biodiversity that have been hard to quantify, including resilience and maintaining options for future generations. This increased appreciation of the importance of conserving “phylogenetic diversity”, from microbial communities in the human gut to global threatened species, has inevitably resulted in an explosion of new indices, methods, and case studies. This book recognizes and responds to the timely opportunity for synthesis and sharing experiences in practical applications. The book recognizes that the challenge of finding a synthesis, and building shared concepts and a shared toolbox, requires both an appreciation of the past and a look into the future. Thus, the book is organized as a flow from history, concepts and philosophy, through to methods and tools, and followed by selected case studies. A positive vision and plan of action emerges from these chapters, that includes coping with inevitable uncertainties, effectively communicating the importance of this “evolutionary heritage” to the public and to policy-makers, and ultimately contributing to biodiversity conservation policy from local to global scales.
Download or read book Interactions of Herbicide Atrazine with DNA written by Maria Hepel and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: New methods used for the detection of DNA hybridisation process, including electrochemical, optical scattering, surface plasmon resonance, nanogravimetric, and fluorimetric are described and their application in assays assessing DNA damage is discussed in this book. The analyses of damage and alterations for the DNA in solution as well as for the DNA immobilised on core-shell gold nanoparticles and solid electrodes are presented. These methods enable evaluating the degree of DNA damage caused by toxicants and can be applied to studies of the interactions of atrazine and other herbicides and pesticides with DNA.
Download or read book Adolescents with Autism Spectrum Disorder written by Nicholas W. Gelbar and published by Oxford University Press. This book was released on 2017-12-05 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Adolescents with Autism Spectrum Disorder synthesizes current science on adolescents and young adults with ASD in order to inform mental health practitioners and education professionals who work directly with these individuals"--
Download or read book Excitatory Amino Acids written by Peter H. Seeburg and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book emerging questions of current glutamate research are addressed and new pathways which glutamte research may take in the future discussed. Since glutamate antagonists are still the major hope for the therapy of neurodegenerative disorders in humans, research activities dedicated towards the development of such novel drugs are the focus of public attention. The book comments on the most recent discoveries in the field of neuroprotection and neurodegeneration.
