Download or read book Casarett Doull s Toxicology The Basic Science of Poisons Eighth Edition written by Curtis Klaassen and published by McGraw Hill Professional. This book was released on 2013-04-25 with total page 1473 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most trusted all-in-one overview of the biomedical and environmental aspects of toxicology--NOW more complete, up-to-date, and in full color The world's leading and most authoritative textbook on poisons has more to offer students,toxicologists, and pharmacologists than ever before. Now in full color, and thoroughly revised, the eighth edition of Casarett & Doull's TOXICOLOGY: The Basic Science of Poisons not only delivers a comprehensive review of the essential components of toxicology, it offers the most up-to-date,revealing, and in-depth look at the systemic responses of toxic substance available anywhere. Combined with the latest thinking by the field's foremost scholars plus solid coverage of general principles, modes of action, and chemical-specific toxicity, this landmark text continues to set the standard for toxicology references. NEW to the Eighth Edition FULL-COLOR design to allow for a clearer interpretationof the basic components of toxicology featured throughout the text EXPANDED tables, illustrations, and other visuals areupdated with state-of-the-art standards that makes thisedition even more current and relevant DVD with image bank features all tables and illustrations from the text in presentation-ready format NEW CHAPTERS include "Toxic Effects of Calories"and "Toxic Effects of Nanoparticles"

Download or read book Casarett Doull s Toxicology The Basic Science of Poisons Eighth Edition written by Louis J. Casarett and published by McGraw Hill Professional. This book was released on 2013-06-19 with total page 1474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Accompanying DVD-ROM in pocket at the rear of book.

Download or read book Casarett Doull s Toxicology The Basic Science of Poisons Seventh Edition written by Curtis Klaassen and published by McGraw Hill Professional. This book was released on 2007-11-20 with total page 1332 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most complete, trusted reference text covering the full span of medical toxicology A Doody's Core Title ESSENTIAL PURCHASE for 2011! "This reference stands alone as the basic text in the field of toxicology. This authoritative reference is written by many distinguished professionals in the field, and offers clear, concise descriptions of the key concepts in toxicology. It is extensive and complete, covering a broad range of topics in sufficient detail. Both as a reference and as an educational tool, this book exceeds its goal of serving as a reference for toxicologists, other scientists, and students of the discipline. 3 Stars."--Doody's Review Service Long established as the gold standard in the field, Casarett & Doull's Toxicology equips you with an unsurpassed understanding of modern toxicology, including the principles, concepts, mechanisms, and modes of thought that are the foundation of the discipline. The new seventh edition features is updated throughout and includes many new contributors and new content on chemical terrorism.

Download or read book Public Health Consequences of E Cigarettes written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-05-18 with total page 775 pages. Available in PDF, EPUB and Kindle. Book excerpt: Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion. Proponents of e-cigarette use also tout the potential benefits of e-cigarettes as devices that could help combustible tobacco cigarette smokers to quit and thereby reduce tobacco-related health risks. Others are concerned about the exposure to potentially toxic substances contained in e-cigarette emissions, especially in individuals who have never used tobacco products such as youth and young adults. Given their relatively recent introduction, there has been little time for a scientific body of evidence to develop on the health effects of e-cigarettes. Public Health Consequences of E-Cigarettes reviews and critically assesses the state of the emerging evidence about e-cigarettes and health. This report makes recommendations for the improvement of this research and highlights gaps that are a priority for future research.

Download or read book Health Effects Assessment Summary Tables written by and published by . This book was released on 1997 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biodegradability of Surfactants written by D.R. Karsa and published by Springer Science & Business Media. This book was released on 1994-12-31 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: The awareness and development of 'biodegradable' surfactants pre-dates current pressures by the environmental movement by nearly three decades, wherein a responsible industry mutually agreed to replace 'hard', non-biodegradable com ponents of household detergents by 'soft', biodegradable alternatives, without course to legislation. The only requirement at that time was for surfactants used in detergents to exhibit a 'primary biodegradability' in excess of 80%; this referring to the disap pearance or removal from solution of the intact surface active material as de tected by specified analytical techniques. This proved useful, as observed environmental impacts of surfactants, e.g. visible foam on rivers, are associated with the intact molecule. Test methods for 'primary biodegradability' were eventually enshrined in EU legislation for nonionic surfactants (Directive 821242/EEC, amended 73/404IEEC) and for anionic surfactants (Directive 8212431EEC, amended 73/405IEEC). No approved test methods and resultant legislation have been developed for cationic and amphoteric surfactants to date. The environmental classification of chemical substances, which of course includes surfactants, and associated risk assessment utilises a second criterion 'ready biodegradability'. This may be assessed by a number of methods which monitor oxygen uptake (BOD), carbon dioxide production or removal of dis solved organic carbon (DOC). Some surfactants which comply with the above Detergents Directive are borderline when it comes to 'ready biodegradability'.

Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of 3 3 dimethylbenzidine Dihydrochloride CAS No 612 82 8 in F344 N Rats drinking Water Studies written by and published by . This book was released on 1991 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of Primidone CAS No 125 33 7 in F344 N Rats and B6C3F1 Mice feed Studies written by and published by . This book was released on 2000 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of Isobutyl Nitrite CAS No 542 56 3 in F344 N Rats and B6C3F1 Mice inhalation Studies written by and published by . This book was released on 1996 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book NTP Toxicity Study Reports written by and published by . This book was released on 1991 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Analytical Determination of Nicotine and Related Compounds and their Metabolites written by J.W. Gorrod and published by Elsevier. This book was released on 1999-11-02 with total page 773 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides for the first time a single comprehensive source of information on the analytical chemistry of nicotine and related alkaloids. The editors have brought together scientists from academia and the tobacco industry to describe the state-of-the-art of the chemistry and analytical methods for measurement of nicotine. Both the scope and detail of the book are impressive. Chapters describe the history, pharmacology and toxicology of nicotine, the biosynthesis of nicotine and other alkaloids in the tobacco plant, the general chemistry of nicotine and the analytical methodologies that have been used to measure nicotine and related alkaloids in biological specimens, in tobacco and pharmaceutical products and in tobacco smoke. There is also a comprehensive review of the chemistry and toxicology of nicotine-derived nitrosamines, an important class of tobacco carcinogens.

Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of 2 2 bis bromomethyl 1 3 propanediol FR 1138 CAS No 3296 90 0 in F344 N Rats and B6C3F1 Mice feed Studies written by and published by . This book was released on 1996 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Technical Report on Toxicology and Carcinogenesis Studies of Propargyl Alcohol CAS No 107 19 7 in F344 N Rats and B6C3F1 Mice Inhalation Studies written by J. J. Butler and published by . This book was released on 2009-03 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Propargyl alcohol is a commercially available acetylenic primary alcohol. It is used in a variety of chemical manufacturing processes and to protect steel from becoming brittle. The researchers studied propargyl alcohol to determine if it caused cancer in rats or mice. All groups of animals exposed to propargyl alcohol experienced a variety of lesions in the epithelial tissues of the nose, including hyperplase, metaplasia, and inflammation. Adenomas of the respiratory epithelium of the nose were observed in male rats and in male and female mice exposed to propargyl alcohol. The rate of mononuclear cell leukemia was also increased in exposed male rats, and the rate of Harderian gland edenomas was increased in exposed male mice. Illus.

Download or read book NTP Technical Bulletin written by National Toxicology Program (U.S.) and published by . This book was released on 1980 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Technical Report on Toxicology and Carcinogenesis Studies of A Methylstyrene CAS No 98 83 9 in F344 N Rats and B6C3F1 Mice Inhalation Studies written by M. E. Wyde and published by DIANE Publishing. This book was released on 2008-04 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: a-Methylstyrene is used to make heat-resistant acrylonitrile-butadiene-styrene resins & polymers. This report studies the effects of a-methylstyrene on male & female rats & mice to identify potential toxic or cancer-related hazards. It concludes that exposure to a-methylstyrene in the air caused kidney tumors, & possibly mononuclear cell leukemia, in male rats. It concludes that a-methylstyrene caused liver cancer in female mice, & also possibly in male mice. Charts, tables, graphs & plates.

Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of Nickel Sulfate Hexahydrate CAS No 10101 97 0 in F344 N Rats and B6C3F1 Mice inhalation Studies written by and published by . This book was released on 1996 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of Sodium Tungstate Dihydrate CASRN 10213 10 2 in Sprague Dawley Hsd Sprague Dawley r SD r Rats and B6C3F1 N Mice Drinking Water Studies written by and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: PERINATAL AND THREE-MONTH STUDY IN RATS: Beginning on GD\s6, groups of eight F0\stime-mated female rats were exposed to ST in drinking water throughout gestation and lactation at one of five exposure concentrations (125, 250, 500, 1,000, or 2,000\smg/L) or were provided the vehicle control (deionized water). Groups of 10 F1\srats per sex continued on in the study after weaning and were given drinking water containing the same respective ST concentrations for 3\smonths. There were no significant effects of ST exposure on pregnancy status, maternal survival, or littering parameters. By the end of lactation, dams in the 1,000 and 2,000\smg/L groups showed significant decreases in group mean body weight of approximately 10% and 18%, respectively, and water consumption was significantly decreased for the 500, 1,000, and 2,000\smg/L groups relative to the vehicle control group over the LD\s17 to LD\s21 interval. When adjusted for litter size, the mean body weight of male and female pups in the 2,000\smg/L group on PND\s21 was significantly decreased by approximately 16% and 11%, respectively, compared to the corresponding vehicle control groups. There were no early deaths during the 3-month study. When compared to the vehicle control group, final mean body weights were lower for the 1,000 and 2,000\smg/L males and 2,000 mg/L females. Water consumption was lower for the 1,000 and 2,000\smg/L males and females. The urine xanthine/creatinine ratios were significantly increased in all male and female exposed groups. Serum insulin concentrations were significantly decreased in the 2,000\smg/L males relative to the vehicle control males. Significantly decreased absolute weights were observed in several organs but were considered secondary to body weights reductions. Exposure-related histological lesions were limited to the kidneys and included increased incidences of renal tubule regeneration in the 1,000 and 2,000\smg/L males and females; the increases in the 2,000\smg/L groups were significant relative to the vehicle control group. CONCLUSIONS: Under the conditions of these 2-year drinking water studies, there was no evidence of carcinogenic activity of sodium tungstate dihydrate (ST) in male Hsd:Sprague Dawley(r) SD(r) rats at exposure concentrations of 250, 500, or 1,000\smg/L. There was equivocal evidence of carcinogenic activity of ST in female Hsd:Sprague Dawley(r) SD(r) rats based on increased incidences of C-cell adenoma or carcinoma (combined) of the thyroid gland. There was equivocal evidence of carcinogenic activity of ST in male B6C3F1/N mice based on the occurrences of renal tubule adenoma or carcinoma (combined) in exposed animals. There was no evidence of carcinogenic activity of ST in female B6C3F1/N mice at exposure concentrations of 500, 1,000, or 2,000\smg/L. Exposure to ST in drinking water caused increased incidences of nonneoplastic lesions in the kidney of male and female rats and mice, in the uterus of female rats, in the large intestine of male and female mice, and in the testes of male mice.SYNONYMS: Tungstic acid sodium salt dehydrate.