Download or read book Novel Tools for the Study of Structural and Functional Networks in the Brain written by Luis M. Colon-Perez and published by Frontiers Media SA. This book was released on 2018-04-27 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Throughout the history of neuroscience, technological advances are the drivers behind many major advances in our understanding of the nervous system. Investigations of the structure and function of the brain take place on multiple scales, including macroscale at the level of brain regions, mesoscale at the level of neuronal populations, and microscale at the level of single neurons and neuron to neuron interactions. Integration of knowledge over these scales requires novel techniques and interpretations. In this research topic, we highlight nine articles that integrate structural and functional approaches to study brain networks.

Download or read book Networks of the Brain written by Olaf Sporns and published by MIT Press. This book was released on 2016-02-12 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: An integrative overview of network approaches to neuroscience explores the origins of brain complexity and the link between brain structure and function. Over the last decade, the study of complex networks has expanded across diverse scientific fields. Increasingly, science is concerned with the structure, behavior, and evolution of complex systems ranging from cells to ecosystems. In Networks of the Brain, Olaf Sporns describes how the integrative nature of brain function can be illuminated from a complex network perspective. Highlighting the many emerging points of contact between neuroscience and network science, the book serves to introduce network theory to neuroscientists and neuroscience to those working on theoretical network models. Sporns emphasizes how networks connect levels of organization in the brain and how they link structure to function, offering an informal and nonmathematical treatment of the subject. Networks of the Brain provides a synthesis of the sciences of complex networks and the brain that will be an essential foundation for future research.

Download or read book Neuronal Networks in Brain Function CNS Disorders and Therapeutics written by Carl Faingold and published by Academic Press. This book was released on 2013-12-26 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understanding of: How the brain carries out important tasks via networks How these networks interact in normal brain function Major mechanisms that control network function The interaction of the normal networks to produce more complex behaviors How brain disorders can result from abnormal interactions How therapy of disorders can be advanced through this network approach This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders. Utilizes perspectives and tools from various neuroscience subdisciplines (cellular, systems, physiologic), making the volume broadly relevant Chapters explore normal network function and control mechanisms, with an eye to improving therapies for brain disorders Reflects predominant disciplinary shift from an anatomical to a functional perspective of the brain Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

Download or read book Fundamentals of Brain Network Analysis written by Alex Fornito and published by Academic Press. This book was released on 2016-03-04 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Brain Network Analysis is a comprehensive and accessible introduction to methods for unraveling the extraordinary complexity of neuronal connectivity. From the perspective of graph theory and network science, this book introduces, motivates and explains techniques for modeling brain networks as graphs of nodes connected by edges, and covers a diverse array of measures for quantifying their topological and spatial organization. It builds intuition for key concepts and methods by illustrating how they can be practically applied in diverse areas of neuroscience, ranging from the analysis of synaptic networks in the nematode worm to the characterization of large-scale human brain networks constructed with magnetic resonance imaging. This text is ideally suited to neuroscientists wanting to develop expertise in the rapidly developing field of neural connectomics, and to physical and computational scientists wanting to understand how these quantitative methods can be used to understand brain organization. Extensively illustrated throughout by graphical representations of key mathematical concepts and their practical applications to analyses of nervous systems Comprehensively covers graph theoretical analyses of structural and functional brain networks, from microscopic to macroscopic scales, using examples based on a wide variety of experimental methods in neuroscience Designed to inform and empower scientists at all levels of experience, and from any specialist background, wanting to use modern methods of network science to understand the organization of the brain

Download or read book Handbook of Brain Connectivity written by Viktor K. Jirsa and published by Springer. This book was released on 2007-08-16 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our contemporary understanding of brain function is deeply rooted in the ideas of the nonlinear dynamics of distributed networks. Cognition and motor coordination seem to arise from the interactions of local neuronal networks, which themselves are connected in large scales across the entire brain. The spatial architectures between various scales inevitably influence the dynamics of the brain and thereby its function. But how can we integrate brain connectivity amongst these structural and functional domains? Our Handbook provides an account of the current knowledge on the measurement, analysis and theory of the anatomical and functional connectivity of the brain. All contributors are leading experts in various fields concerning structural and functional brain connectivity. In the first part of the Handbook, the chapters focus on an introduction and discussion of the principles underlying connected neural systems. The second part introduces the currently available non-invasive technologies for measuring structural and functional connectivity in the brain. Part three provides an overview of the analysis techniques currently available and highlights new developments. Part four introduces the application and translation of the concepts of brain connectivity to behavior, cognition and the clinical domain.

Download or read book Systems Neuroscience written by Albert Cheung-Hoi Yu and published by Springer. This book was released on 2018-10-17 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edition of Advances in Neurobiology brings together experts in the emerging field of Systems Neuroscience to present an overview of this area of research. Topics covered include: how different neural circuits analyze sensory information, form perceptions of the external world, make decisions, and execute movements; how nerve cells behave when connected together to form neural networks; the relationship between molecular and cellular approaches to understanding brain structure and function; the study of high-level mental functions; and studying brain pathologies and diseases with Systems Neuroscience. A hierarchy of biological complexity arises from the genome, transcriptome, proteome, organelles, cells, synapses, circuits, brain regions, the whole brain, and behaviour. The best way to study the brain, the most complex organ in the body composed of 100 billion cells with trillions of interconnections, is with a Systems Biology approach. Systems biology is an inter-disciplinary field that focuses on complex interactions within biological systems to reveal 'emergent properties' - properties of cells and groups of cells functioning as a system whose actual and theoretical description is only possible using Systems Biology techniques.

Download or read book Advancing Our Understanding of Structure and Function in the Brain Developing Novel Approaches for Network Inference and Emergent Phenomena written by Chris G. Antonopoulos and published by Frontiers Media SA. This book was released on 2021-02-09 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Discovering the Human Connectome written by Olaf Sporns and published by MIT Press. This book was released on 2012-08-31 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: A pioneer in the field outlines new empirical and computational approaches to mapping the neural connections of the human brain. Crucial to understanding how the brain works is connectivity, and the centerpiece of brain connectivity is the connectome, a comprehensive description of how neurons and brain regions are connected. In this book, Olaf Sporns surveys current efforts to chart these connections—to map the human connectome. He argues that the nascent field of connectomics has already begun to influence the way many neuroscientists collect, analyze, and think about their data. Moreover, the idea of mapping the connections of the human brain in their entirety has captured the imaginations of researchers across several disciplines including human cognition, brain and mental disorders, and complex systems and networks. Discovering the Human Connectome offers the first comprehensive overview of current empirical and computational approaches in this rapidly developing field.

Download or read book Micro Meso and Macro Connectomics of the Brain written by Henry Kennedy and published by Springer. This book was released on 2016-03-10 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.

Download or read book The Routledge Handbook of Philosophy and Science of Addiction written by Hanna Pickard and published by Routledge. This book was released on 2018-06-13 with total page 1427 pages. Available in PDF, EPUB and Kindle. Book excerpt: The problem of addiction is one of the major challenges and controversies confronting medicine and society. It also poses important and complex philosophical and scientific problems. What is addiction? Why does it occur? And how should we respond to it, as individuals and as a society? The Routledge Handbook of Philosophy and Science of Addiction is an outstanding reference source to the key topics, problems and debates in this exciting subject. It spans several disciplines and is the first collection of its kind. Organised into three clear parts, forty-five chapters by a team of international contributors examine key areas, including: the meaning of addiction to individuals conceptions of addiction varieties and taxonomies of addiction methods and models of addiction evolution and addiction history, sociology and anthropology population distribution and epidemiology developmental processes vulnerabilities and resilience psychological and neural mechanisms prevention, treatment and spontaneous recovery public health and the ethics of care social justice, law and policy. Essential reading for students and researchers in addiction research and in philosophy, particularly philosophy of mind and psychology and ethics, The Routledge Handbook of Philosophy and Science of Addiction will also be of great interest to those in related fields, such as medicine, mental health, social work, and social policy.

Download or read book Human Brain Function written by Karl J. Friston and published by Elsevier. This book was released on 2004-01-26 with total page 1144 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated second edition provides the state of the art perspective of the theory, practice and application of modern non-invasive imaging methods employed in exploring the structural and functional architecture of the normal and diseased human brain. Like the successful first edition, it is written by members of the Functional Imaging Laboratory - the Wellcome Trust funded London lab that has contributed much to the development of brain imaging methods and their application in the last decade. This book should excite and intrigue anyone interested in the new facts about the brain gained from neuroimaging and also those who wish to participate in this area of brain science. * Represents an almost entirely new book from 1st edition, covering the rapid advances in methods and in understanding of how human brains are organized * Reviews major advances in cognition, perception, emotion and action * Introduces novel experimental designs and analytical techniques made possible with fMRI, including event-related designs and non-linear analysis

Download or read book Connectome Analysis written by Markus D. Schirmer and published by Academic Press. This book was released on 2023-06-30 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Connectome Analysis: Characterization, Methods, and Analysis is a comprehensive companion for the analysis of brain networks, or connectomes. The book provides sources of constituent structural and functional MRI signals, network construction and practices for analysis, cutting-edge methods that address the latest challenges in neuroscience, and the fundamentals of network theory in the context of giving practical methods for building connectomes for analysis. Emphasis is placed on quality control of the individual analysis steps. Subsequent chapters discuss networks in neuroscience in clinical and general populations, including how findings are related to underlying neurophysiology and neuropsychology. This book is aimed at students and early-career researchers in brain connectomics and neuroimaging who have a background in computer science, mathematics and physics, as well as more broadly to neuroscientists and psychologists who want to start incorporating connectomics into their research. Provides practical recommendations on how to construct, assess and analyze brain networks Gives an understanding of all the technical methods for connectome analysis Presents the basic network theoretical principles typically used in neuroscience Covers the latest tools and data repositories that are freely available for the reader to carry out connectomic analyses

Download or read book Neural Organization written by Michael A. Arbib and published by MIT Press. This book was released on 1998 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Neural Organization, Arbib, Erdi, and Szentagothai integrate structural, functional, and dynamical approaches to the interaction of brain models and neurobiologcal experiments. Both structure-based "bottom-up" and function- based "top-down" models offer coherent concepts by which to evaluate the experimental data. The goal of this book is to point out the advantages of a multidisciplinary, multistrategied approach to the brain.Part I of Neural Organization provides a detailed introduction to each of the three areas of structure, function, and dynamics. Structure refers to the anatomical aspects of the brain and the relations between different brain regions. Function refers to skills and behaviors, which are explained by means of functional schemas and biologically based neural networks. Dynamics refers to the use of a mathematical framework to analyze the temporal change of neural activities and synaptic connectivities that underlie brain development and plasticity--in terms of both detailed single-cell models and large-scale network models.In part II, the authors show how their systematic approach can be used to analyze specific parts of the nervous system--the olfactory system, hippocampus, thalamus, cerebral cortex, cerebellum, and basal ganglia--as well as to integrate data from the study of brain regions, functional models, and the dynamics of neural networks. In conclusion, they offer a plan for the use of their methods in the development of cognitive neuroscience."

Download or read book Neonatal Questions and Controversies Neurology written by Jeffrey M Perlman and published by Elsevier Health Sciences. This book was released on 2023-08-21 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Richard Polin’s Neonatology Questions and Controversies series highlights the toughest challenges facing physicians and care providers in clinical practice, offering trustworthy guidance on up-to-date diagnostic and treatment options in the field. In each volume, renowned experts address the clinical problems of greatest concern to today’s practitioners, helping you handle difficult practice issues and provide optimal, evidence-based care to every patient. The thoroughly updated, full-color, 4th Edition of Neurology: Provides a clear management strategy for common and rare neonatal neurological disorders, offering guidance based on the most up-to-date understanding of underlying pathophysiology. Places emphasis on controversial areas that can entail different approaches. Features the most current clinical information throughout, including recent trials for hypoxic-ischemic encephalopathy, acute management of symptomatic seizures, and congenital viral meningoencephalitis: neonatal herpes simplex virus, congenital cytomegalovirus, congenital Zika, and COVID-19. Includes three new chapters on neurological and neurobehavioral evaluation in the neonatal period; white matter injury; and cerebellar hemorrhage in the premature infant. Highlights gaps in knowledge that should serve as a strong stimulus for future research. Utilizes a consistent chapter organization to help you find information quickly and easily, and contains numerous charts, graphs, radiographic images, and photographs throughout. Offers the most authoritative advice available from world-class neonatologists/neurologists who share their knowledge of new trends and developments in neonatal care. Purchase each volume individually, or get the entire 7-volume Neonatology Questions and Controversies set, which includes online access that allows you to search across all titles! Gastroenterology and Nutrition Hematology and Transfusion Medicine Neonatal Hemodynamics Infectious Disease, Immunology, and Pharmacology Renal, Fluid, and Electrolyte Disorders Neurology The Newborn Lung

Download or read book The Graph Theoretical Approach in Brain Functional Networks written by Fabrizio Fallani and published by Springer Nature. This book was released on 2022-06-01 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book illustrates the theoretical aspects of several methodologies related to the possibility of i) enhancing the poor spatial information of the electroencephalographic (EEG) activity on the scalp and giving a measure of the electrical activity on the cortical surface. ii) estimating the directional influences between any given pair of channels in a multivariate dataset. iii) modeling the brain networks as graphs. The possible applications are discussed in three different experimental designs regarding i) the study of pathological conditions during a motor task, ii) the study of memory processes during a cognitive task iii) the study of the instantaneous dynamics throughout the evolution of a motor task in physiological conditions. The main outcome from all those studies indicates clearly that the performance of cognitive and motor tasks as well as the presence of neural diseases can affect the brain network topology. This evidence gives the power of reflecting cerebral "states" or "traits" to the mathematical indexes derived from the graph theory. In particular, the observed structural changes could critically depend on patterns of synchronization and desynchronization - i.e. the dynamic binding of neural assemblies - as also suggested by a wide range of previous electrophysiological studies. Moreover, the fact that these patterns occur at multiple frequencies support the evidence that brain functional networks contain multiple frequency channels along which information is transmitted. The graph theoretical approach represents an effective means to evaluate the functional connectivity patterns obtained from scalp EEG signals. The possibility to describe the complex brain networks sub-serving different functions in humans by means of "numbers" is a promising tool toward the generation of a better understanding of the brain functions. Table of Contents: Introduction / Brain Functional Connectivity / Graph Theory / High-Resolution EEG / Cortical Networks in Spinal Cord Injured Patients / Cortical Networks During a Lifelike Memory Task / Application to Time-varying Cortical Networks / Conclusions

Download or read book Neuroimaging Approaches to the Study of Cognitive Aging written by Ronald Cohen and published by Frontiers Media SA. This book was released on 2020-07-29 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Connectomics written by Brent C. Munsell and published by Academic Press. This book was released on 2018-09-08 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Connectomics: Applications to Neuroimaging is unique in presenting the frontier of neuro-applications using brain connectomics techniques. The book describes state-of-the-art research that applies brain connectivity analysis techniques to a broad range of neurological and psychiatric disorders (Alzheimer’s, epilepsy, stroke, autism, Parkinson’s, drug or alcohol addiction, depression, bipolar, and schizophrenia), brain fingerprint applications, speech-language assessments, and cognitive assessment. With this book the reader will learn: Basic mathematical principles underlying connectomics How connectomics is applied to a wide range of neuro-applications What is the future direction of connectomics techniques. This book is an ideal reference for researchers and graduate students in computer science, data science, computational neuroscience, computational physics, or mathematics who need to understand how computational models derived from brain connectivity data are being used in clinical applications, as well as neuroscientists and medical researchers wanting an overview of the technical methods. Features: Combines connectomics methods with relevant and interesting neuro-applications Covers most of the hot topics in neuroscience and clinical areas Appeals to researchers in a wide range of disciplines: computer science, engineering, data science, mathematics, computational physics, computational neuroscience, as well as neuroscience, and medical researchers interested in the technical methods of connectomics Combines connectomics methods with relevant and interesting neuro-applications Presents information that will appeal to researchers in a wide range of disciplines, including computer science, engineering, data science, mathematics, computational physics, computational neuroscience, and more Includes a mathematics primer that formulates connectomics from an applied point-of-view, thus avoiding difficult to understand theoretical perspective Lists publicly available neuro-imaging datasets that can be used to construct structural and functional connectomes