Download or read book Novel Insights Into a Functional HIV Cure written by Taisuke Izumi and published by Frontiers Media SA. This book was released on 2022-01-17 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book HIV Vaccines and Cure written by Linqi Zhang and published by Springer. This book was released on 2018-07-20 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive review of the major barriers to HIV cure and vaccine. It covers the fundamental virology and immunology leading to HIV transmission, protection from infection and long term HIV persistence on antiretroviral therapy. In addition, strategies being tested to eliminate persistent HIV and the rational design of vaccines to induce protective immunity are covered. This book also discusses the challenges related to the design of clinical trials for testing the safety and efficacy of these innovative approaches. This book will provide a systematic overview and also discuss controversial issues for researchers in virology and immunology, as well as practicing physicians, and scientists in the pharmaceutical industry.

Download or read book HIV 1 Latency written by Guido Silvestri and published by Springer. This book was released on 2018-10-11 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.

Download or read book Insights in virology 2021 written by Chunfu Zheng and published by Frontiers Media SA. This book was released on 2023-04-28 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Novel Insights into The Immunology of Pulmonary Granulomatous Diseases written by Mary Jane Thomassen and published by Frontiers Media SA. This book was released on 2021-02-09 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Human Immunodeficiency Virus written by Emilio Emini and published by Princeton University Press. This book was released on 2021-04-13 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past few years have witnessed an explosive increase in our collective knowledge of the biology of the human immunodeficiency virus (HIV). Researchers have acquired new understanding of the virus's biochemistry, molecular biology, pathogenesis, genetics, and immunobiology. Resulting therapeutic advances have significantly prolonged the lives of thousands. Yet, the need to develop better therapies is ever more acute and--given the virus's continued spread through the human population--the need for an effective vaccine is urgent. These goals can be accomplished only through the experienced synthesis of information from the many disciplines participating in HIV research and through the insights of new investigators. This volume is designed to lower the barriers imposed on investigators by the sheer volume of available information--information that often can be found only in far-flung and specialized journals. It provides, in a single resource, an in-depth overview of the diverse areas that constitute HIV research. The result is a broad introduction for students and researchers new to the field as well as an integrated overview for researchers specialized in particular areas of HIV investigation. The volume will also benefit those seeking technical understanding of the virus's biology, including physicians treating HIV-infected patients. Each chapter is a comprehensive presentation of one area of current AIDS research--including work on the virus life cycle, epidemiology, genetics, protease and reverse transcriptase inhibitors, receptor and co-receptor interactions, therapeutic targets, clinical treatment, immunobiology, and vaccines--written by a leading researcher in that area. The contributors are Jon P. Anderson, Jan Balzarini, Elana Cherry, Thomas J. Coates, Chris Collins, Jon H. Condra, Mark B. Feinberg, Richard B. Gaynor, Matthias Götte, Daria J. Hazuda, Spyros Kalams, Nathaniel R. Landau, Gerald H. Learn, Norman L. Letvin, James I. Mullins, Willscott E. Naugler, David Nickle, Matthew Rain, Allen G. Rodrigo, Daniel Shriner, Shalom Spira, Mario Stevenson, Todd Summers, Catherine Ulich, Joseph P. Vacca, Mark A. Wainberg, Bruce D. Walker, and Yang Wang.

Download or read book Disease Control Priorities Third Edition Volume 6 written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Download or read book Novel Insights into Inflammatory Roles of Mast Cells and Basophils written by Satoshi Tanaka and published by Frontiers Media SA. This book was released on 2023-04-20 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Virology Essays for the Living the Dead and the Small Things in Between written by Joseph Osmundson and published by W. W. Norton & Company. This book was released on 2022-06-07 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Named a Most Anticipated Book of 2022 by Literary Hub A leading microbiologist tackles the scientific and sociopolitical impact of viruses in twelve striking essays. Invisible in the food we eat, the people we kiss, and inside our own bodies, viruses flourish—with the power to shape not only our health, but our social, political, and economic systems. Drawing on his expertise in microbiology, Joseph Osmundson brings readers under the microscope to understand the structure and mechanics of viruses and to examine how viruses like HIV and COVID-19 have redefined daily life. Osmundson’s buoyant prose builds on the work of the activists and thinkers at the forefront of the HIV/AIDS crisis and critical scholars like José Esteban Munoz to navigate the intricacies of risk reduction, draw parallels between queer theory and hard science, and define what it really means to “go viral.” This dazzling multidisciplinary collection offers novel insights on illness, sex, and collective responsibility. Virology is a critical warning, a necessary reflection, and a call for a better future.

Download or read book HIV AIDS in the Post HAART Era written by John C. Hall and published by PMPH-USA. This book was released on 2011 with total page 1052 pages. Available in PDF, EPUB and Kindle. Book excerpt: The science of the virus and its effects and the clinical approaches to its treatment and transmission prevention are placed in the context of the history and epidemiology of the HIV-AIDS pandemic. Each organ system of the body is explored as to manifestations of the disease, treatment now and in the future, as well as what the disease has taught us about the immune response. The science of epidemiology, which is so important in allowing for tracking of the disease and potential limitation of transmission, is another aspect of AIDS explored in detail. The pandemic manifests differently in different parts of the world, and the relevance of the volume is enhanced by its international group of contributors. No other text provides the historical and epidemiological context of this disease along with an update of diagnosis and treatment. The underlying science and epidemiology of AIDS are not neglected, so the student or clinician who is treating patients with AIDS can gain a full understanding of HIV/AIDS in individual patients and in their communities.

Download or read book Novel Insights Into the Immune Mechanisms Associated With the Pathogenesis of Chagas Disease written by Giovane R. Sousa and published by Frontiers Media SA. This book was released on 2022-06-16 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book HIV 1 Integrase written by Nouri Neamati and published by John Wiley & Sons. This book was released on 2011-08-10 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Despite numerous review articles and isolated book chapters dealing with HIV-1 integrase, there has not been a single source for those working to devise anti-AIDS drugs against this promising target. But this book fills that gap and offers a valuable introduction to the field for the interdisciplinary scientists who will need to work together to design drugs that target HIV-1 integrase.

Download or read book Chimpanzees in Biomedical and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 2012-01-05 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as research subjects. The Institute of Medicine, in collaboration with the National Research Council, conducted an in-depth analysis of the scientific necessity for chimpanzees in NIH-funded biomedical and behavioral research. The committee concludes that while the chimpanzee has been a valuable animal model in the past, most current biomedical research use of chimpanzees is not necessary, though noted that it is impossible to predict whether research on emerging or new diseases may necessitate chimpanzees in the future.

Download or read book AIDS written by Gary Null and published by Seven Stories Press. This book was released on 2002-03-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this first book to bring both establishment and dissenting views of the AIDS crisis into one volume, Gary Null unravels the halftruths that many argue have marred the study of this disease from the start. In clear, jargon-free prose, the book offers an unbiased, unflinching discussion of all sides of each issue. AIDS: A Second Opinion argues that the AIDS drama has exposed problematic issues having to do with the functioning of U.S. medical institutions. Null explores a new type of health care, grounded in patients' own choices and dispositions, that poses a challenge to the top-down, expert-controlled medical systems favored by the establishment. Drawing from Null's many years of study of alternative, traditional, and orthodox medicine as well as from interviews with many long-term survivors, the book dissects the claims of the AZT and drug-cocktail approach to treating AIDS and offers a trilogy of treatment strategies based on wide views of how to enhance the immune system and improve overall functioning.

Download or read book Lymph Node T Cell Dynamics and Novel Strategies for HIV Cure written by Constantinos Petrovas and published by Frontiers Media SA. This book was released on 2019-02-11 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently, more than 36 million people are infected with HIV. Although the introduction of highly active anti-retroviral therapy (HAART) has led to substantial advances in the clinical management of HIV infected individuals, HAART cannot completely eliminate the virus. This is because CD4 T helper cells, harboring the virus, remain dormant reservoirs. These reservoirs are difficult to measure and are present even in HAART-treated HIV infected individuals with undetectable levels of HIV in the blood. A growing body of studies has revealed follicular helper (Tfh) CD4 T cells, a highly differentiated CD4 T cell population localized in immunologically sanctuary sites (follicle/germinal center), as a major reservoir of HIV. The present Frontiers in Immunology eBook compiles 16 timely review articles focusing on the dynamics of major follicular immune cell types in HIV/SIV infection and their potential role for disease pathogenesis and the viral persistence in the lymph node. This eBook provides a comprehensive presentation of recent published work on lymph node and especially Tfh cell dynamics in HIV infection and we hope that it will be useful for our further understanding of how such dynamics affect the interplay between virus and host as well as for the discovery of novel therapeutic targets in the fight against HIV.

Download or read book Mapping AIDS written by Lukas Engelmann and published by Cambridge University Press. This book was released on 2018-11-08 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers an innovative study of visual traditions in modern medical history through debates about the causes, impact and spread of AIDS.

Download or read book New Insights into HIV AIDS for Students and Healthcare Professionals written by Esther Olufunmilayo Asekun-Olarinmoye and published by Cambridge Scholars Publishing. This book was released on 2019-01-24 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first case of HIV was diagnosed in 1981, several efforts have gone into its prevention and control. However, it remains a leading scourge today, with no cure despite the international attention and publicity it receives. It is one of the few diseases specifically given attention in the Millennium Development Goals (MDG) and the Sustainable Development Goals (SDGs). There has been inadequate effort by academia in developing countries towards contributing to in-depth knowledge of HIV, as well as stimulating the interest of students in the topic. As the search for a cure continues, this book is timely, discussing the changing epidemiology of HIV. The contributors are not only academicians, but also seasoned programmers who are working in the realm of HIV care.