Download or read book Nouveaux analogues de l acide glutamique par transamination mol culaire written by Emmanuelle Sagot and published by . This book was released on 2007 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Le glutamate (Glu) est le principal neurotransmetteur excitateur du système nerveux central. Ses analogues peuvent se comporter comme des ligands sélectifs et sont intéressants pour élucider le rôle spécifique des différents types de transporteurs ou de récepteurs du système glutamatergique. Ce travail avait pour objectif de synthétiser de nouveaux analogues fonctionnalisés du Glu en utilisant les aminotransférases en tant que biocatalyseurs de façon à convertir les analogues de l'acide 2-oxoglutarique (KG) en analogues du Glu. La plupart des analogues du KG se sont avéré substrats de l'Aspartate Aminotransférase d'E. coli (AspAT) permettant la préparation stéréosélective des analogues du Glu correspondants. Une étude de modélisation moléculaire a été réalisée afin d'expliquer la spécificité de substrat de l'AspAt. Quatre analogues se sont comportés comme des ligands sélectifs et offrent des perspectives pour le développement de nouveaux analogues actifs dans le système glutamatergique

Download or read book Clinical Chronopharmacology written by Alain Reinberg and published by CRC Press. This book was released on 1990-07 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Periodical and predictable changes in biological susceptibility and response to a large variety of chemical agents, including drugs and food, have been documented since the early 1970s. This book provides a survey of clinically-documented research in chronopharmacology.

Download or read book Minimum competence in scientific English written by Sue Blattes and published by L'Editeur : EDP Sciences. This book was released on 2003 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cet ouvrage, devenu célèbre sous son sigle MCSE, a déjà été utilisé par plus de 50 000 étudiants, chercheurs, professionnels. L'objectif est de lire et écrire des textes en anglais scientifique avec facilité et pertinence. L'ouvrage est conçu pour que l'apprenant devienne un véritable utilisateur de l'anglais. La méthode originale repose sur l'analyse des fonctions et structures nécessaires : measurement, frequency, comparison, modification, link words, time, cause and consequence, hypothesis, modality, purpose and process, impersonal forms, compound nouns and adjectives. Dans chaque unit, des tests d'auto-évaluation permettent de se situer et de construire son parcours de formation, d'abord en définissant ses objectifs à l'aide des key points et du lexis, puis, de façon plus personnalisée, en puisant dans les examples in context, checkpoints (back to basics, word web), web search, FAQs... MCSE est l'outil de base d'une méthode qui comprend aussi d'autres outils dans la même collection (Listening Comprehension for Scientiflc English et Speaking Skills in Scientitic English). L'ouvrage est destiné à tout apprenant de niveau baccalauréat qui désire acquérir une réelle compétence dans l'écriture et la lecture de textes en anglais scientifique.

Download or read book Biological Rhythm Research written by A. Sollberger and published by . This book was released on 1965 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book An Introduction to Differential Manifolds written by Jacques Lafontaine and published by Springer. This book was released on 2015-07-29 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an introduction to differential manifolds. It gives solid preliminaries for more advanced topics: Riemannian manifolds, differential topology, Lie theory. It presupposes little background: the reader is only expected to master basic differential calculus, and a little point-set topology. The book covers the main topics of differential geometry: manifolds, tangent space, vector fields, differential forms, Lie groups, and a few more sophisticated topics such as de Rham cohomology, degree theory and the Gauss-Bonnet theorem for surfaces. Its ambition is to give solid foundations. In particular, the introduction of “abstract” notions such as manifolds or differential forms is motivated via questions and examples from mathematics or theoretical physics. More than 150 exercises, some of them easy and classical, some others more sophisticated, will help the beginner as well as the more expert reader. Solutions are provided for most of them. The book should be of interest to various readers: undergraduate and graduate students for a first contact to differential manifolds, mathematicians from other fields and physicists who wish to acquire some feeling about this beautiful theory. The original French text Introduction aux variétés différentielles has been a best-seller in its category in France for many years. Jacques Lafontaine was successively assistant Professor at Paris Diderot University and Professor at the University of Montpellier, where he is presently emeritus. His main research interests are Riemannian and pseudo-Riemannian geometry, including some aspects of mathematical relativity. Besides his personal research articles, he was involved in several textbooks and research monographs.

Download or read book Endocrine Rhythms written by Dorothy T. Krieger and published by . This book was released on 1979 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Application of Mutation Breeding Methods in the Improvement of vegetatively propagated crops V2 written by C. Broertjes and published by Elsevier. This book was released on 2012-12-02 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Application of Mutation Breeding Methods in the Improvement of Vegetatively Propagated Crops: An Interpretive Literature Review summarizes advances in the use of artificially induced mutations to improve cultivated plants, particularly those that are vegetatively propagated. It brings together all available and accessible references that examine the advantages, drawbacks, and possibilities of the mutation breeding method, as well as the challenges that prevent it from being applied to various crops. Comprised of eight chapters, this volume begins with an overview of various aspects of mutagenic treatment using chemical and physical mutagens. It then discusses the structure and functioning of shoot apices and their behavior after irradiation; adventitious bud techniques and other in vivo or in vitro methods of asexual propagation; and breeding of root and tuber crops, such as cassava and potato, ornamental crops such as foliage plants and cut flowers, fruit crops, and other crops. Plant breeders who want to better understand how to apply mutation breeding to their crops will find this book extremely helpful.

Download or read book Textbook on Endocrinology written by and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Measurement of Linkage in Heredity written by Kenneth Mather and published by . This book was released on 1951 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Handbook of physiology written by William Ferguson Hamilton and published by . This book was released on 1963 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Seventy Generations of Selection for Oil and Protein in Maize written by John Wesley Dudley and published by . This book was released on 1974 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nuclear Techniques for Seed Protein Improvement written by and published by . This book was released on 1973 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Seed Proteins written by W. Gottschalk and published by Springer Science & Business Media. This book was released on 1983-04-30 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Investigations on seed proteins have been intensively carried out during the past two decades. This is valid with regard to both their chemical composition as well as their nutritive value. The development of new biochemical and physical methods has resulted in obtaining deep insights into the structures of seed proteins and their mutual interactions. Intensive exchange of information between the scientists participating in national and international research programmes has given strong impulses for intensifying the research in this field. For the quantitative and quali tative investigations of seed proteins, not only some model plants were used; on the contrary, they were carried out on a large number of different crops important for different regions of the earth. In this way, a level of knowledge has been reached which could not be expected in this diversity within such a short period. This holds not only true for biochemical but also for physiological characters of the species of the limiting amino acids studied. With regard to nutritional aspects, the problem was of special interest, but also seed proteins acting as antinutritional factors were analysed in detail. Based on the knowledge of seed protein structures, it was possible to perform investigations on the genetic basis of their synthesis. This was done under two different aspects: The basic knowledge on the genes involved should be widened; moreover, it should be tried to improve the seed proteins quantitatively and qualitatively under the influence of mutant genes.

Download or read book Barley Genetics III written by and published by . This book was released on 1976 with total page 849 pages. Available in PDF, EPUB and Kindle. Book excerpt: