Download or read book Note on the Preparation of Mouse Tails for Intravenous Injection written by Miriam Posner Finkel and published by . This book was released on 1951 with total page 22 pages. Available in PDF, EPUB and Kindle. Book excerpt: The intravenous administration of solutions into mice is usually done by injection into one of the lateral tail veins. In albino mice these veins are quite conspicuous and easily entered, particularly if the mouse is a young adult, (2 to 3 months old). Customarily, a pre-injection dilatation of the vessels is accomplished by bathing the tail in warm water. The tail is then wiped dry, and the return of blood form the tail prevented by exerting gentle pressure at the base of the tail. As soon as the hypodermic needle has entered the swollen vein, the pressure is released and the injection completed.
Download or read book Nuclear Science Abstracts written by and published by . This book was released on 1951 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Small Animal Imaging written by Fabian Kiessling and published by Springer. This book was released on 2017-05-22 with total page 871 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook is a practical guide to the use of small animal imaging in preclinical research that will assist in the choice of imaging modality and contrast agent and in study design, experimental setup, and data evaluation. All established imaging modalities are discussed in detail, with the assistance of numerous informative illustrations. While the focus of the new edition remains on practical basics, it has been updated to encompass a variety of emerging imaging modalities, methods, and applications. Additional useful hints are also supplied on the installation of a small animal unit, study planning, animal handling, and cost-effective performance of small animal imaging. Cross-calibration methods and data postprocessing are considered in depth. This new edition of Small Animal Imaging will be an invaluable aid for researchers, students, and technicians involved in research into and applications of small animal imaging.
Download or read book Bacterial Extracellular Vesicles written by Steven Jay and published by Springer Nature. This book was released on with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Methods of Behavior Analysis in Neuroscience written by Jerry J. Buccafusco and published by CRC Press. This book was released on 2000-08-29 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic
Download or read book Pharmacogenomics written by Federico Innocenti and published by Humana Press. This book was released on 2013-07-04 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding an individual's genetic makeup is the key to creating personalized drugs with greater efficacy and safety, and pharmacogenomics aims to study the complex genetic basis of inter-patient variability in response to drug therapy. Based upon the success of its first edition, the second edition of Pharmacogenomics: Methods And Protocols aims to continue providing readers with high-quality content on the most innovative and commonly adopted technologies in the field of pharmacogenomics as presented by experts in the field. Broken into several sections, this detailed volume examines techniques for interrogating variation in human genes and genomes, functional assessment of genetic variation, both in vitro and in vivo, as well as tools for translation and implementation of pharmacogenetic markers. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to the respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Comprehensive and thoroughly updated, Pharmacogenomics: Methods And Protocols, Second Edition serves as an essential reference and an invaluable source on the latest information in this field.
Download or read book Vaccine Design written by Sunil Thomas and published by Springer Nature. This book was released on 2021-12-16 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a practical guide providing step-by-step protocol to design and develop vaccines for human diseases. Divided into three volumes, Volume 1: Vaccines for Human Diseases guides readers through an introductory section on future challenges for vaccinologists and the immunological mechanism of vaccines. Chapters focus on design of human vaccines for viral, bacterial, fungal, and parasitic diseases as well as tumor vaccines. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Vaccine Design: Methods and Protocols, Second Edition, Volume 1: Vaccines for Human Diseases aims to be a useful practical guide to researchers to help further their study in this field.
Download or read book The Code of Federal Regulations of the United States of America written by and published by . This book was released on 1970 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Code of federal regulations is the codification of the general and permanent rules published in the Federal register by the executive departments and agencies of the federal government.
Download or read book Code of Federal Regulations written by and published by . This book was released on 1985 with total page 982 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Platelets and Megakaryocytes written by Jonathan M. Gibbins and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: 12 The average human body has in the order of 10 circulating platelets. They are crucial for hemostasis, and yet excessive platelet activation is a major cause of m- bidity and mortality in western societies. It is therefore not surprising that platelets have become one of the most extensively investigated biological cell types. We are, however, far from understanding precisely how platelets become activated under physiological and pathophysiological conditions. In addition, there are large gaps in our knowledge of platelet production from their giant precursor cell, the megakar- cyte. Understanding megakaryocyte biology will be crucial for the development of platelet gene targeting. The aim of Platelets and Megakaryocytes is therefore to bring together established and recently developed techniques to provide a comprehensive guide to the study of both the platelet and the megakaryocyte. It consists of five s- tions split between two volumes. The more functional assays appear in Volume 1, whereas Volume 2 includes signaling techniques, postgenomic methods, and a n- ber of key perspectives chapters. Part I of Volume 1, Platelets and Megakaryocytes: Functional Assays, describes many well established approaches to the study of platelet function, including aggregometry, secretion, arachidonic acid metabolism, procoagulant responses, pla- let adhesion under static or flow conditions, flow cytometry, and production of microparticles. Although one would ideally wish to perform experiments with human platelets, studies within the circulation using intravital microscopy require the use of animal models, which are described in Chapter 16, vol. 1.
Download or read book Breast Cancer Research Protocols written by Susan A. Brooks and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of both well-established and cutting-edge methods for investigating breast cancer biology not only in the laboratory, but also in clinical settings. These readily reproducible techniques solve a variety of problems, ranging from how to collect, store, and prepare human breast tumor samples for analysis, to analyzing cells in vivo and in vitro. Additional chapters address the technology of handling biopsies, new methods for analyzing genes and gene expression, markers of clinical outcome and progress, analysis of tumor-derived proteins and antigens, validating targets, and investigating the biology of newly discovered genes.
Download or read book The Veterinary Laboratory and Field Manual 3rd Edition written by Susan C. Cork and published by 5m Books Ltd. This book was released on 2019-06-03 with total page 751 pages. Available in PDF, EPUB and Kindle. Book excerpt: Isolated regions of the world are often at the forefront of emerging diseases and, to be effective in disease prevention and control, they require basic resources for field sample collection and testing in conditions vastly different from those available in well-equipped reference laboratories. Technical support for field extension staff, and the availability of reliable diagnostic testing facilities, are also vital to ensure sustainable livelihoods for subsistence farmers. This technical handbook aims to provide an easy to follow overview of the basic laboratory techniques, and sample collection guidelines, that we consider useful for staff working in district veterinary facilities in regions that lack the infrastructural support available for staff with ready access to national veterinary laboratories. The Veterinary Laboratory and Field Manual 3rd Edition provides the reader with a summary of basic diagnostic procedures and sample submission guidelines and also advocates for improved communication between animal health extension staff, veterinarians, laboratory staff and farmers. Case studies are used to illustrate key concepts. Basic laboratory disciplines are covered including parasitology, microbiology, haematology, serology / immunology and pathology. There are also sections on laboratory infrastructure and equipment. There is additional content on common clinical presentations, One Health approaches to Antimicrobial resistance, the role of the OIE, disease surveillance and wildlife disease monitoring. Supplementary tools for use in the field and laboratory are also available online. This new edition of The Veterinary Laboratory and Field Manual is updated to include content on pen side tests, selection and integration of new technologies, engagement with international agencies and programs, and the One Health approach to disease monitoring. Animal Health extension staff in isolated regions of the world, and NGOs, can benefit from this book as well as policy makers supporting veterinary work in rural areas and veterinary para-professionals involved in One Health work. 5m Books
Download or read book Memory B Cells written by Kim L. Good-Jacobson and published by Springer Nature. This book was released on with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Current List of Medical Literature written by and published by . This book was released on 1951 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes section, "Recent book acquisitions" (varies: Recent United States publications) formerly published separately by the U.S. Army Medical Library.
Download or read book Atomics and Atomic Engineering written by and published by . This book was released on 1951 with total page 892 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Animal Biotechnology written by Ashish S. Verma and published by Academic Press. This book was released on 2020-06-23 with total page 798 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal Biotechnology: Models in Discovery and Translation, Second Edition, provides a helpful guide to anyone seeking a thorough review of animal biotechnology and its application to human disease and welfare. This updated edition covers vital fundamentals, including animal cell cultures, genome sequencing analysis, epigenetics and animal models, gene expression, and ethics and safety concerns, along with in-depth examples of implications for human health and prospects for the future. New chapters cover animal biotechnology as applied to various disease types and research areas, including in vitro fertilization, human embryonic stem cell research, biosensors, enteric diseases, biopharming, organ transplantation, tuberculosis, neurodegenerative disorders, and more. Highlights the latest biomedical applications of genetically modified and cloned animals, with a focus on cancer and infectious diseases Offers first-hand accounts of the use of biotechnology tools, including molecular markers, stem cells, animal cultures, tissue engineering, ADME and CAM Assay Includes case studies that illustrate safety assessment issues, ethical considerations, and intellectual property rights associated with the translation of animal biotechnology studies
Download or read book Positron Emission Tomography written by Timothy H. Witney and published by Springer Nature. This book was released on 2023-11-25 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume explores key concepts and experimental design related to Positron Emission Tomography (PET) imaging that have revolutionized our understanding of human biology. The first part focuses on recent advances in radiotracer probe development to enable the detection of materials, from large macromolecules to complicated drug-like structures. The next section describes how key physiological and pathophysiological processes can be interrogated and quantifiably measured with this imaging technique. Finally, chapters examine important technological developments in the field that are revolutionizing the way these innovative PET probes are utilized in the clinic. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Positron Emission Tomography: Methods and Protocols serves as an ideal guide for researchers looking to use imaging to revolutionize the way we diagnose and treat disease.
