Download or read book Non Interventional Studies Considerations when Managing and Conducting Non Interventional Studies in Europe Part 2 written by Stuart McCully and published by CHCUK. This book was released on 2009 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Non Interventional Studies Europe Part 2 written by and published by CHCUK. This book was released on with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Non Interventional Studies Europe Part 1 written by and published by CHCUK. This book was released on with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Registries for Evaluating Patient Outcomes written by Agency for Healthcare Research and Quality/AHRQ and published by Government Printing Office. This book was released on 2014-04-01 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. For the purposes of this guide, a patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves one or more predetermined scientific, clinical, or policy purposes. A registry database is a file (or files) derived from the registry. Although registries can serve many purposes, this guide focuses on registries created for one or more of the following purposes: to describe the natural history of disease, to determine clinical effectiveness or cost-effectiveness of health care products and services, to measure or monitor safety and harm, and/or to measure quality of care. Registries are classified according to how their populations are defined. For example, product registries include patients who have been exposed to biopharmaceutical products or medical devices. Health services registries consist of patients who have had a common procedure, clinical encounter, or hospitalization. Disease or condition registries are defined by patients having the same diagnosis, such as cystic fibrosis or heart failure. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews.
Download or read book Improving Healthcare Quality in Europe Characteristics Effectiveness and Implementation of Different Strategies written by OECD and published by OECD Publishing. This book was released on 2019-10-17 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, developed by the Observatory together with OECD, provides an overall conceptual framework for understanding and applying strategies aimed at improving quality of care. Crucially, it summarizes available evidence on different quality strategies and provides recommendations for their implementation. This book is intended to help policy-makers to understand concepts of quality and to support them to evaluate single strategies and combinations of strategies.
Download or read book Sharing Clinical Trial Data written by Institute of Medicine and published by National Academies Press. This book was released on 2015-04-20 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data sharing can accelerate new discoveries by avoiding duplicative trials, stimulating new ideas for research, and enabling the maximal scientific knowledge and benefits to be gained from the efforts of clinical trial participants and investigators. At the same time, sharing clinical trial data presents risks, burdens, and challenges. These include the need to protect the privacy and honor the consent of clinical trial participants; safeguard the legitimate economic interests of sponsors; and guard against invalid secondary analyses, which could undermine trust in clinical trials or otherwise harm public health. Sharing Clinical Trial Data presents activities and strategies for the responsible sharing of clinical trial data. With the goal of increasing scientific knowledge to lead to better therapies for patients, this book identifies guiding principles and makes recommendations to maximize the benefits and minimize risks. This report offers guidance on the types of clinical trial data available at different points in the process, the points in the process at which each type of data should be shared, methods for sharing data, what groups should have access to data, and future knowledge and infrastructure needs. Responsible sharing of clinical trial data will allow other investigators to replicate published findings and carry out additional analyses, strengthen the evidence base for regulatory and clinical decisions, and increase the scientific knowledge gained from investments by the funders of clinical trials. The recommendations of Sharing Clinical Trial Data will be useful both now and well into the future as improved sharing of data leads to a stronger evidence base for treatment. This book will be of interest to stakeholders across the spectrum of research-from funders, to researchers, to journals, to physicians, and ultimately, to patients.
Download or read book Image Guided Interventions E Book written by Kenneth R. Thomson and published by Elsevier Health Sciences. This book was released on 2020-03-13 with total page 1193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised to reflect recent, rapid changes in the field of interventional radiology (IR), Image-Guided Interventions, 3rd Edition, offers comprehensive, narrative coverage of vascular and nonvascular interventional imaging—ideal for IR subspecialists as well as residents and fellows in IR. This award-winning title provides clear guidance from global experts, helping you formulate effective treatment strategies, communicate with patients, avoid complications, and put today’s newest technology to work in your practice. Offers step-by-step instructions on a comprehensive range of image-guided intervention techniques, including discussions of equipment, contrast agents, pharmacologic agents, antiplatelet agents, and classic signs, as well as detailed protocols, algorithms, and SIR guidelines. Includes new chapters on Patient Preparation, Prostate Artery Embolization, Management of Acute Aortic Syndrome, Percutaneous Arterial Venous Fistula Creation, Lymphatic Interventions, Spinal and Paraspinal Nerve Blocks, and more. Employs a newly streamlined format with shorter, more digestible chapters for quicker reference. Integrates new patient care and communication tips throughout to address recent changes in practice. Highlights indications and contraindications for interventional procedures, and provides tables listing the materials and instruments required for each. Features more than 2,300 state-of-the-art images demonstrating IR procedures, full-color illustrations of anatomical structures and landmarks, and video demonstrations online. 2014 BMA Medical Book Awards Highly Commended in Radiology category!
Download or read book Drug Utilization Research written by Monique Elseviers and published by John Wiley & Sons. This book was released on 2024-10-21 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: Towards a better understanding of how medicines are used in society Drug Utilization Research (DUR) is a discipline which combines aspects of pharmacotherapy, epidemiology, and health services research into an interdisciplinary set of methods for analyzing and assessing the prescribing, dispensing and consumption of medicines. It combines both qualitative and quantitative approaches to facilitate the safe and effective use of pharmaceuticals. Drug Utilization Research: Methods and Applications provides a comprehensive introduction to this discipline, prepared by an international team of authors with broad experience in numerous fields. Now reorganized and updated to reflect the latest research and global challenges, it is an indispensable resource for understanding the use of pharmaceuticals. Readers of the second edition of Drug Utilization Research will find: New chapters on methods, including more hands-on guidance on how to plan and conduct different types of drug utilization A section on specific applications in areas such as psychotropics, opioids, cancer drugs, antibacterials, and cardiovascular drugs A new section with case studies illustrating applications of DUR in different continents Detailed treatment of subjects including DUR and health policy, DUR in specific populations, and many more Drug Utilization Research is ideal for epidemiologists, pharmacists, physicians, nurses and others interested in drug use and its outcomes.
Download or read book Principles and Practice of Pharmacovigilance and Drug Safety written by Jimmy Jose and published by Springer Nature. This book was released on with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book European Pain Management written by Christopher Eccleston and published by Oxford University Press. This book was released on 2018 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: European Pain Management provides a review of the organization of pain care in the 37 member countries, providing the first authoritative summary, description, and coordinated challenge establishing the authority of pain centres in Europe.
Download or read book Cochrane Handbook for Systematic Reviews of Interventions written by Julian P. T. Higgins and published by Wiley. This book was released on 2008-11-24 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves.
Download or read book Improving Diagnosis in Health Care written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2015-12-29 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Getting the right diagnosis is a key aspect of health care - it provides an explanation of a patient's health problem and informs subsequent health care decisions. The diagnostic process is a complex, collaborative activity that involves clinical reasoning and information gathering to determine a patient's health problem. According to Improving Diagnosis in Health Care, diagnostic errors-inaccurate or delayed diagnoses-persist throughout all settings of care and continue to harm an unacceptable number of patients. It is likely that most people will experience at least one diagnostic error in their lifetime, sometimes with devastating consequences. Diagnostic errors may cause harm to patients by preventing or delaying appropriate treatment, providing unnecessary or harmful treatment, or resulting in psychological or financial repercussions. The committee concluded that improving the diagnostic process is not only possible, but also represents a moral, professional, and public health imperative. Improving Diagnosis in Health Care, a continuation of the landmark Institute of Medicine reports To Err Is Human (2000) and Crossing the Quality Chasm (2001), finds that diagnosis-and, in particular, the occurrence of diagnostic errorsâ€"has been largely unappreciated in efforts to improve the quality and safety of health care. Without a dedicated focus on improving diagnosis, diagnostic errors will likely worsen as the delivery of health care and the diagnostic process continue to increase in complexity. Just as the diagnostic process is a collaborative activity, improving diagnosis will require collaboration and a widespread commitment to change among health care professionals, health care organizations, patients and their families, researchers, and policy makers. The recommendations of Improving Diagnosis in Health Care contribute to the growing momentum for change in this crucial area of health care quality and safety.
Download or read book Infection Prevention and Control in Healthcare Part II Clinical Management of Infections An Issue of Infectious Disease Clinics of North America E Book written by Keith S. Kaye and published by Elsevier Health Sciences. This book was released on 2021-11-02 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infection Prevention and Control in Healthcare, Part II: Clinical Management of Infections, An Issue of Infectious Disease Clinics of North America, E-Book
Download or read book Cardiovascular Intervention written by Deepak L. Bhatt and published by Elsevier Health Sciences. This book was released on 2023-09-08 with total page 780 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the renowned Braunwald family of references, Cardiovascular Intervention: A Companion to Braunwald’s Heart Disease provides today’s clinicians with clear, authoritative guidance on every aspect of catheterization of the heart and vasculature and the latest imaging technologies. This practical reference on interventional cardiology is organized from a procedural perspective, with chapters focused exclusively on how to manage complex cardiovascular disease. Now fully updated from cover to cover, the 2nd Edition offers authoritative and current point-of-care coverage of this highly complex, technology-driven specialty—an ideal resource for practitioners at all levels of experience. Offers concise, focused coverage of all aspects of managing interventional cardiology patients, highlighting cautions, procedural nuances and tips, and outcomes. Covers all the newest catheterization techniques and equipment, including new-generation stents, mechanical support devices, imaging technology, and closure devices. Offers complete coverage of structural heart disease and new developments in heart valve disease, including TAVI and mitral valve procedures. Provides updates on the latest procedures, devices, and clinical guidelines for evidence-based practice. Uses a clear, easy-to-follow organization with separate sections on coronary artery interventions, peripheral artery interventions, cerebrovascular interventions, venous interventions, structural heart interventions, and congenital heart disease. Features more than 506 high-quality illustrations and access to 176 procedural videos. Any additional digital ancillary content may publish up to 6 weeks following the publication date.
Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.
Download or read book Access to Non Summary Clinical Trial Data for Research Purposes Under EU Law written by Daria Kim and published by Springer Nature. This book was released on 2021-10-19 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book draws a unique perspective on the regulation of access to clinical trial data as a case on research and knowledge externalities. Notwithstanding numerous potential benefits for medical research and public health, many jurisdictions have struggled to ensure access to clinical trial data, even at the level of the trial results. Pro-access policy initiatives have been strongly opposed by research-based drug companies arguing that mandatory data disclosure impedes their innovation incentives. Conventionally, access to test data has been approached from the perspective of transparency and research ethics. The book offers a complementary view and considers access to individual patient-level trial data for exploratory analysis as a matter of research and innovation policy. Such approach appears to be especially relevant in the data-driven economy where digital data constitutes a valuable economic resource. The study seeks to define how the rules of access to clinical trial data should be designed to reconcile the policy objectives of leveraging the research potential of data through secondary analysis, on the one hand, and protecting economic incentives of research-based drug companies, on the other hand. Overall, it is argued that the mainstream innovation-based justification for exclusive control over the outcomes of research and development can hardly rationalise trial sponsors’ control over primary data from trials. Instead, access to such data and its robust analysis should be prioritised.
Download or read book Textbook of Clinical Trials written by David Machin and published by John Wiley & Sons. This book was released on 2007-01-11 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now published in its Second Edition, the Textbook of Clinical Trials offers detailed coverage of trial methodology in diverse areas of medicine in a single comprehensive volume. Praise for the First Edition: "... very useful as an introduction to clinical research, or for those planning specific studies within therapeutic or disease areas." BRITISH JOURNAL OF SURGERY, Vol. 92, No. 2, February 2005 The book’s main concept is to describe the impact of clinical trials on the practice of medicine. It separates the information by therapeutic area because the impact of clinical trials, the problems encountered, and the numbers of trials in existence vary tremendously from specialty to specialty. The sections provide a background to the disease area and general clinical trial methodology before concentrating on particular problems experienced in that area. Specific examples are used throughout to address these issues. The Textbook of Clinical Trials, Second Edition: Highlights the various ways clinical trials have influenced the practice of medicine in many therapeutic areas Describes the challenges posed by those conducting clinical trials over a range of medical specialities and allied fields Additional therapeutic areas are included in this Second Edition to fill gaps in the First Edition as the number and complexity of trials increases in this rapidly developing area Newly covered or updated in the Second Edition: general surgery, plastic surgery, aesthetic surgery, palliative care, primary care, anaesthesia and pain, transfusion, wound healing, maternal and perinatal health, early termination, organ transplants, ophthalmology, epilepsy, infectious disease, neuro-oncology, adrenal, thyroid and urological cancers, as well as a chapter on the Cochrane network An invaluable resource for pharmaceutical companies, the Textbook of Clinical Trials, Second Edition appeals to those working in contract research organizations, medical departments and in the area of public health and health science alike.
