Download or read book Non alcoholic Steatohepatitis NASH in Obese Pediatric Patients written by Deborah Monroe Kampschror and published by . This book was released on 2009 with total page 50 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Color Atlas of Pediatric Pathology written by Aliya N. Husain, MD and published by Demos Medical Publishing. This book was released on 2011-02-25 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coverage extends to surgical specimens as well as handling of placentas and autopsies. The atlas features approximately 900 high-quality images supported by concisely written text highlighting the salient diagnostic features as well as important staging and prognostic (including molecular) parameters. Features include: Comprehensive coverage of pediatric surgical and autopsy pathology. Each chapter is presented by a recognized expert. Practical presentation: concise text highlights diagnostic features making the atlas an outstanding resource for the practitioner. Illustrated throughout with approximately 900 full-color images.

Download or read book Global Perspectives on Childhood Obesity written by Debasis Bagchi and published by Academic Press. This book was released on 2010-10-12 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding the complex factors contributing to the growing childhood obesity epidemic is vital not only for the improved health of the world's future generations, but for the healthcare system. The impact of childhood obesity reaches beyond the individual family and into the public arenas of social systems and government policy and programs. Global Perspectives on Childhood Obesity explores these with an approach that considers the current state of childhood obesity around the world as well as future projections, the most highly cited factors contributing to childhood obesity, what it means for the future both for children and society, and suggestions for steps to address and potentially prevent childhood obesity. This book will cover the multi-faceted factors contributing to the rapidly growing childhood obesity epidemic The underlying causes and current status of rapidly growing obesity epidemic in children in the global scenario will be discussed The strategies for childhood obesity prevention and treatment such as physical activity and exercise, personalized nutrition plans and school and community involvement will be presented

Download or read book A Clinical Guide to Pediatric Weight Management and Obesity written by Sandra Gibson Hassink and published by Lippincott Williams & Wilkins. This book was released on 2007 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handy, practical guide provides clinicians with a comprehensive approach to the medical management of overweight children and adolescents. Coverage begins with the epidemiology, pathophysiology, and developmental aspects of child and adolescent obesity and a guide to evaluation of obese children. Subsequent chapters address respiratory, cardiovascular, endocrine, metabolic, orthopaedic, gastrointestinal, renal, and neurologic complications and comorbid conditions as well as mental health issues, acute obesity-related emergencies, and obesity as part of genetic syndromes. Pathophysiology is linked to clinical presentation, evaluation, and treatment, and lifestyle issues are discussed where appropriate. Highlighted boxes and algorithms help clinicians find and digest information quickly.

Download or read book Alcoholic and Non Alcoholic Fatty Liver Disease written by Naga Chalasani and published by Springer. This book was released on 2015-12-10 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the first text to concisely yet comprehensively cover developments for both alcoholic and nonalcoholic fatty liver disease in an organized fashion. Aspects of these two diseases covered in the book include global epidemiology and risk factors, pathogenesis, animal models, hepatic and extra-hepatic malignancies, treatment models, and current and emerging therapies. Written by experts in the field, Alcoholic and Non-Alcoholic Fatty Liver Disease: Bench to Bedside is a valuable resource for gastroenterologists, pathologists, and hepatologists who treat patients with alcoholic and nonalcoholic fatty liver disease.

Download or read book Construction of LMS Parameters for the Centers for Disease Control and Prevention 2000 Growth Charts written by Katherine M. Flegal and published by . This book was released on 2013 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Statistical Methods in Diagnostic Medicine written by Xiao-Hua Zhou and published by John Wiley & Sons. This book was released on 2014-08-21 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the First Edition " . . . the book is a valuable addition to the literature in the field, serving as a much-needed guide for both clinicians and advanced students."—Zentralblatt MATH A new edition of the cutting-edge guide to diagnostic tests in medical research In recent years, a considerable amount of research has focused on evolving methods for designing and analyzing diagnostic accuracy studies. Statistical Methods in Diagnostic Medicine, Second Edition continues to provide a comprehensive approach to the topic, guiding readers through the necessary practices for understanding these studies and generalizing the results to patient populations. Following a basic introduction to measuring test accuracy and study design, the authors successfully define various measures of diagnostic accuracy, describe strategies for designing diagnostic accuracy studies, and present key statistical methods for estimating and comparing test accuracy. Topics new to the Second Edition include: Methods for tests designed to detect and locate lesions Recommendations for covariate-adjustment Methods for estimating and comparing predictive values and sample size calculations Correcting techniques for verification and imperfect standard biases Sample size calculation for multiple reader studies when pilot data are available Updated meta-analysis methods, now incorporating random effects Three case studies thoroughly showcase some of the questions and statistical issues that arise in diagnostic medicine, with all associated data provided in detailed appendices. A related web site features Fortran, SAS®, and R software packages so that readers can conduct their own analyses. Statistical Methods in Diagnostic Medicine, Second Edition is an excellent supplement for biostatistics courses at the graduate level. It also serves as a valuable reference for clinicians and researchers working in the fields of medicine, epidemiology, and biostatistics.

Download or read book Diabetes in Children and Adolescents written by William V. Tamborlane and published by Springer Nature. This book was released on 2021-02-12 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently, available information on pediatric and adolescent diabetes is limited to chapters in larger books covering the broader topic of pediatric endocrinology, and these do not have the space to delve into specific topics. This concise, timely book contains everything that a practicing provider needs to know in order to provide comprehensive, up-to-date care for children and adolescents with diabetes, from the latest methods for diagnosing various types of diabetes to integrating cutting-edge technology in the care of this patient population. Initial management, the use of insulin pumps, continuous glucose monitoring, and automated insulin delivery are discussed in detail, as are nutrition therapy, exercise, psychosocial challenges, acute and long-term complications, and future directions for treatment and research. Further, this book provides clinicians with guidelines for the implementation of best practices as outlined by leading associations such as the American Diabetes Association (ADA) and International Society of Pediatric and Adolescent Diabetes (ISPAD). The Yale Children’s Diabetes Program has been ranked among the best in the United States, including clinicians and researchers who are world-renowned for their efforts in improving the care of children with diabetes. This wealth of knowledge and experience positions the author team well as experts in this field.

Download or read book The Liver written by Irwin M. Arias and published by John Wiley & Sons. This book was released on 2020-03-09 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries in biology and their influence on diagnosing, managing, and preventing liver disease. Seventy new chapters — including substantial original sections on liver cancer and groundbreaking advances that will have significant impact on hepatology — provide comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology. Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume: Relates molecular physiology to understanding disease pathology and treatment Links the science and pathology of the liver to practical clinical applications Features 16 new “Horizons” chapters that explore new and emerging science and technology Includes plentiful full-color illustrations and figures The Liver: Biology and Pathobiology, Sixth Edition is an indispensable resource for practicing and trainee hepatologists, gastroenterologists, hepatobiliary and liver transplant surgeons, and researchers and scientists in areas including hepatology, cell and molecular biology, virology, and drug metabolism.

Download or read book Concise Pediatric and Adolescent Hepatology written by A. Dhawan and published by Karger Medical and Scientific Publishers. This book was released on 2012 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: A broad range of medical and surgical details of pediatric liver disease and liver transplantation Great progress in molecular biology, therapeutics, imaging as well as surgery have vastly improved the understanding and treatment of childhood liver disorders. In particular, surgical advancements in liver transplantation currently allow for a lower age or weight limit for recipients. Furthermore, the majority of children with liver disease or with liver transplantation today survive well into adulthood. In this book, world experts in the now established subspecialty of pediatric hepatology provide a comprehensive summary of the latest advances in pathophysiology, molecular diagnostics and treatment strategies. Day-to-day management of liver transplant recipients as well as psychosocial aspects and complications during the challenging transition phase to adulthood are discussed in detail. This up-to-date overview will be an invaluable tool for trainees in pediatric gastroenterology, a ready reference for busy clinicians and nurses or allied health professionals involved in the care of children with liver disease and after liver transplantation.

Download or read book Non Alcoholic Fatty Liver Disease An Issue of Clinics in Liver Disease written by Paul J. Gaglio and published by Elsevier Health Sciences. This book was released on 2016-08-09 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to the current obesity epidemic, non-alcoholic fatty liver disease (NAFLD) is prevalent in a significant portion of the United States patient population. It is being increasingly recognized that NAFLD affects both adults and children and can progress to end stage liver disease with resultant cirrhosis, portal hypertension, and hepatocellular carcinoma. In addition, several extrahepatic conditions may be linked to NAFLD including cardiovascular disease, insulin requiring and type 2 diabetes mellitus, obstructive sleep apnea, colonic adenomas, hyperuricemia, vitamin D deficiency, hyperferritinemia, pancreatic steatosis, hypothyroidism, and polycystic ovarian syndrome. Therapies for NAFLD are evolving rapidly. This issue will analyze patient demographics, risk factors, pathophysiology, patient presentation, and treatments for NAFLD.

Download or read book Obesity written by George L. Blackburn and published by Jones & Bartlett Learning. This book was released on 1994 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines the disease of obesity and its metabolic consequences. Explores obesity in relation to physiological and psychological health, and describes the clinical aspects of properly evaluating obese patients. Discusses the roles of dietary factors, appetite, exercise, metabolism, and the endocrine system in obesity, as well as the effects of significant weight loss on long-term health. Also discusses the psychology of obesity, weight loss, and regain. Provides practitioners with detailed guidelines for selecting and implementing multidisciplinary treatment that incorporates dietary intervention, exercise, behavior modification and stress management, and, when necessary, surgery or pharmacotherapy. Emphasizes matching patients with clinical interventions and treatment settings, and presents strategies for maintaining weight loss. Illustrates how to design interventions appropriate for the hospital, physician's office, clinic, home and workplace, and how to integrate different types of interventions in multiple settings. Written for physicians, dietitians, phychiatrists,

Download or read book Diagnosis of Liver Disease written by Etsuko Hashimoto and published by Springer. This book was released on 2019-07-18 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book guides practitioners in the assessment of patients with a liver problem. The emphasis is on the role of macro- and microscopic pathology in elucidating pathogenesis as well as identifying confounding features of image findings that may lead to a more elaborate differential diagnosis. If appropriate, the role of light and electron microscopic examination, along with the role of specific stains and molecular techniques, is illustrated. In addition, the concept of each liver disease is summarized briefly and its up-to-data is provided, and unresolved problems in diagnosis, treatment, and pathogenesis are clearly described.The approach in this book is a practical one with a focus on the evaluation of illustrative cases, simultaneously demonstrating cross-sectional images (ultrasonography, computed tomography, magnetic resonance imaging, and angiography), pathological findings, and peritoneoscopic images. The diagnosis and therapy are summed up in helpful tables, and association of clinical manifestations with image analysis and pathological findings is shown to be important in differential diagnosis and treatment. With the authors comprising internationally renowned experts, this book will serve as a useful source of information for medical students, physicians, internists, hepatologists, gastroenterologists, radiologists, and pathologists worldwide.

Download or read book Human Maternal Obesity in the Development of Nonalcoholic Fatty Liver Disease in a Germ free Mouse Model written by Taylor Kristina Soderborg and published by . This book was released on 2019 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Maternal metabolism and obesity contribute significantly to the risk of obesity and non-alcoholic fatty liver disease (NAFLD) in the next generation, however the causal drivers of this relationship are currently unclear. Metabolic diseases in the pediatric population pose a unique challenge as the mechanisms driving their onset and progression are hypothesized to be the result of programming by early life exposures in addition to lifestyle factors. The earlier onset of obesity and NAFLD in the pediatric population is associated with a worse natural history and progression of these conditions compared to adults. At the time of diagnosis, half of pediatric patients have the more progressive, inflammatory version of NAFLD, non-alcoholic steatohepatitis (NASH), and those diagnosed in childhood have a worse prognosis that adults. Despite the alarming rate of pediatric NAFLD worldwide, particularly in obese youth, at present there are no interventions that have convincingly demonstrated efficacy to alter the progression of this disease. Importantly, given the involvement of inflammation in pediatric NASH, as demonstrated by a unique periportal inflammation, it is likely that the pathogenesis of NAFLD in children may have distinct features from that in adults. Evidence of leaky gut barriers in children with NASH in addition to histological evidence portal inflammation, suggests that the early gut microbiome may play a significant role in pediatric NAFLD. Early life dysbiosis has been found in offspring of obese and/or high fat diet fed mothers in both human, non-human primate and murine models. Research in humans also suggests that excessive gestational weight gain (EWG) and gestational diabetes mellitus (GDM) can also influence offspring microbiome composition. However, there are very limited prospective human data on the influence of commonly co-morbid metabolic conditions, such as EWG and obesity, or, GDM and obesity, on offspring gut colonization. Importantly, while there is correlative data associating early dysbiosis with worse metabolic outcomes in human offspring, causality has not yet been established. Throughout the following work we build upon the existing knowledge of how maternal phenotype influences human offspring microbiome composition and develop mechanistic connections between the altered gut microbiota and metabolic disease risk in a germ-free mice model. We demonstrate in a germ-free mouse model a causative role for this dysbiosis in predisposition to obesity and NAFLD upon exposure to a western style diet. Specifically, we discovered that dysbiosis results in a hypo-responsive bone marrow derived macrophage with dysfunction of both classical and alternative metabolism in a germ-free mouse model. Similar to the influence of maternal obesity on the human infant gut microbiome, we find that EWG and GDM independently and through their interaction with obesity, uniquely influence the composition of the human offspring microbiome at 2 weeks of life. Our findings suggest that maternal metabolic phenotype influences the colonization of the early human infant gut with lasting alterations of the innate immune system, as suggested by our germ-free mouse model. These results expand upon the current understanding of how maternal metabolic obesity, EWG and GDM in humans influences the human offspring gut microbiome and also provide insight to the mechanism by which maternal obesity could potentially cause NAFLD, as demonstrated in germ-free mice. This work supports targeting the early life microbiome in the development of effective preventative measures to impair the perpetuation of metabolic disease in the next generation.

Download or read book Essentials of Anatomic Pathology written by Liang Cheng and published by Springer Science & Business Media. This book was released on 2011-03-18 with total page 1867 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the 8 years since the publication of the first edition of Essentials of Anatomic Pathology, great strides have been made in our understanding of diseases and neoplastic processes. Many clinically important new histopathologic entities have been described or more fully defined in virtually every organ. Numerous clinically important diagnostic and prognostic markers have entered routine practice. Genetic testing for the early detection of cancers and the molecular classification of diseases has become increasingly important. This is an age of enlightenment in surgical pathology, and the authors of this new volume have captured this sense of excitement herein. This much praised and widely used reference manual on has been extensively revised and expanded to cover the entire field of anatomic pathology. The Third Edition features the incorporation of full-color images in the text with updates of new diagnostic and prognostic information. New classifications and numerous new entities and histologic variants are fully explored. Useful immunostaining biomarkers and emerging molecular targets and relevant molecular findings that have emerged from recent genomic studies are incorporated in each chapter. Written by internationally recognized authorities, the comprehensive, evidence-based practice information is presented in an outline format that is clear and easy to follow. Up-to-date and richly detailed, Essentials of Anatomic Pathology, Third Edition offers both the pathologist-in-training and the practicing pathologist a concise summary of all the critical information needed to recognize, understand and interpret anatomic pathology.

Download or read book Pediatric Obesity From the Spectrum of Clinical Physiology Social Psychology and Translational Research written by Ching-Feng Cheng and published by Frontiers Media SA. This book was released on 2021-11-23 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book 2000 CDC Growth Charts for the United States written by and published by . This book was released on 2002 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: