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Book NMR MRI with Hyperpolarized Gas and High Tc SQUID

Download or read book NMR MRI with Hyperpolarized Gas and High Tc SQUID written by and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A method and apparatus for the detection of nuclear magnetic resonance (NMR) signals and production of magnetic resonance imaging (MRI) from samples combines the use of hyperpolarized inert gases to enhance the NMR signals from target nuclei in a sample and a high critical temperature (Tc) superconducting quantum interference device (SQUID) to detect the NMR signals. The system operates in static magnetic fields of 3 mT or less (down to 0.1 mT), and at temperatures from liquid nitrogen (77K) to room temperature. Sample size is limited only by the size of the magnetic field coils and not by the detector. The detector is a high Tc SQUID magnetometer designed so that the SQUID detector can be very close to the sample, which can be at room temperature.

Book High Tc SQUIDs for Biomedical Applications  Immunoassays  Magnetoencephalography  and Ultra Low Field Magnetic Resonance Imaging

Download or read book High Tc SQUIDs for Biomedical Applications Immunoassays Magnetoencephalography and Ultra Low Field Magnetic Resonance Imaging written by Fredrik Öisjöen and published by Springer Science & Business Media. This book was released on 2012-07-25 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis describes the challenging task of developing high critical temperature superconducting quantum interference devices (high-Tc SQUIDs) and using them as sensors for biomedical applications, including magnetic immunoassays, magnetoencephalography and magnetic resonance imaging (MRI). The first part of this work discusses the development of fast magnetic immunoassays, which can be used to improve the sensitivity, or to create new, unique point-of-care diagnostics systems. The second part shows that high-Tc SQUIDs might make magnetoencephalography more available, thus opening the field of high-Tc SQUID-based magnetoencephalography for recording brain functions. This technique can be combined with ultra-low field MRI which is discussed in the last part. This combination may provide a new unique tool for studies of brain functions. This work does not simply improve on existing technology but opens possibilities for novel advanced medical devices and techniques.

Book Ultra low Field Magnetic Resonance Using Optically Pumped Noble Gases and SQUID Detection

Download or read book Ultra low Field Magnetic Resonance Using Optically Pumped Noble Gases and SQUID Detection written by Annjoe Golangco Wong-Foy and published by . This book was released on 2001 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Nuclear Magnetic Resonance

Download or read book Nuclear Magnetic Resonance written by G A Webb and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a spectroscopic method, nuclear magnetic resonance (NMR) has seen spectacular growth over the past two decades, both as a technique and in its applications. Today the applications of NMR span a wide range of scientific disciplines, from physics to biology to medicine. Each volume of Nuclear Magnetic Resonance comprises a combination of annual and biennial reports which together provide comprehensive coverage of the literature on this topic. This Specialist Periodical Report reflects the growing volume of published work involving NMR techniques and applications, in particular NMR of natural macromolecules which is covered in two reports: "NMR of Proteins and Nucleic Acids" and "NMR of Carbohydrates, Lipids and Membranes". For those wanting to become rapidly acquainted with specific areas of NMR, this title provides unrivalled scope of coverage. Seasoned practitioners of NMR will find this an invaluable source of current methods and applications. Volume 33 covers literature published from June 2002 to May 2003. Specialist Periodical Reports provide systematic and detailed review coverage in major areas of chemical research. Compiled by teams of leading authorities in the relevant subject areas, the series creates a unique service for the active research chemist, with regular, in-depth accounts of progress in particular fields of chemistry. Subject coverage within different volumes of a given title is similar and publication is on an annual or biennial basis.

Book NMR Spectroscopy and Imaging of Hyperpolarized Gases

Download or read book NMR Spectroscopy and Imaging of Hyperpolarized Gases written by and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of the nuclear magnetic resonance (NMR) phenomenon, countless NMR techniques have been developed that are today indispensable tools in physics, chemistry, biology, and medicine. As one of the main obstacles in NMR is its notorious lack of sensitivity, different hyperpolarization (HP) methods have been established to increase signals up to several orders of magnitude. In this work, different aspects of magnetic resonance, using HP noble gases, are studied, hereby combining different disciplines of research. The first part examines new fundamental effects in NMR of HP gases, in theory and experiment. The spin echo phenomenon, which provides the basis of numerous modern experiments, is studied in detail in the gas phase. The changes of the echo signal in terms of amplitude, shape, and position, due to the fast translational motion, are described by an extension of the existing theory and computer simulations. With this knowledge as a prerequisite, the detection of intermolecular double-quantum coherences was accomplished for the first time in the gas phase. The second part of this thesis focuses on the development of a practical method to enhance the dissolution process of HP 129Xe, without loss of polarization or shortening of T1. Two different setups for application in NMR spectroscopy and magnetic resonance imaging (MRI) are presented. The continuous operation allows biological and multidimensional spectroscopy in solutions. Also, first in vitro MRI images with dissolved HP 129Xe as contrast agent were obtained at a clinical scanner.

Book Official Gazette of the United States Patent and Trademark Office

Download or read book Official Gazette of the United States Patent and Trademark Office written by United States. Patent and Trademark Office and published by . This book was released on 2000 with total page 1316 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book The SQUID Handbook

    Book Details:
  • Author : John Clarke
  • Publisher : John Wiley & Sons
  • Release : 2006-12-13
  • ISBN : 3527609504
  • Pages : 653 pages

Download or read book The SQUID Handbook written by John Clarke and published by John Wiley & Sons. This book was released on 2006-12-13 with total page 653 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume handbook offers a comprehensive and coordinated presentation of SQUIDs (Superconducting Quantum Interference Devices), including device fundamentals, design, technology, system construction and multiple applications. It is intended to bridge the gap between fundamentals and applications, and will be a valuable textbook reference for graduate students and for professionals engaged in SQUID research and engineering. It will also be of use to specialists in multiple fields of practical SQUID applications, from human brain research and heart diagnostics to airplane and nuclear plant testing to prospecting for oil, minerals and buried ordnance. While the first volume presents the theory and fabrication of SQUIDs, the second volume is devoted to applications. It starts with an important aspect of the analysis of measured magnetic signals generated by current sources (the inverse problem), and includes several chapters devoted to various areas of application, namely biomagnetism (research on and diagnostics of human brain, heart, liver, etc.), detection of extremely weak signals, for example electromagnetic radiation and Nuclear Magnetic Resonance. The volume closes with a chapter on motion detectors and the detection of gravity waves.

Book NMR Spectroscopy and Imaging of Hyperpolarized Gases

Download or read book NMR Spectroscopy and Imaging of Hyperpolarized Gases written by Paul-Philipp Zänker and published by . This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Hyperpolarized Gases in MRI

Download or read book Hyperpolarized Gases in MRI written by H.-U. Kauczor and published by . This book was released on 2000 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Enhancement of NMR and MRI in the Presence of Hyperpolarized Noble Gases

Download or read book Enhancement of NMR and MRI in the Presence of Hyperpolarized Noble Gases written by and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The present invention relates generally to nuclear magnetic resonance (NMR) techniques for both spectroscopy and imaging. More particularly, the present invention relates to methods in which hyperpolarized noble gases (e.g., Xe and He) are used to enhance and improve NMR and MRI. Additionally, the hyperpolarized gas solutions of the invention are useful both in vitro and in vivo to study the dynamics or structure of a system. When used with biological systems, either in vivo or in vitro, it is within the scope of the invention to target the hyperpolarized gas and deliver it to specific regions within the system.

Book Squid Detected NMR and MRI at Ultralow Fields

Download or read book Squid Detected NMR and MRI at Ultralow Fields written by and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned dc superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals.

Book The SQUID Handbook

Download or read book The SQUID Handbook written by J. Clarke and published by Wiley-VCH. This book was released on 2006 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume handbook offers a comprehensive and coordinated presentation of SQUIDs (Superconducting Quantum Interference Devices), including device fundamentals, design, technology, system construction and multiple applications. It is intended to bridge the gap between fundamentals and applications, and will be a valuable textbook reference for graduate students and for professionals engaged in SQUID research and engineering. It will also be of use to specialists in multiple fields of practical SQUID applications, from human brain research and heart diagnostics to airplane and nuclear plant testing to prospecting for oil, minerals and buried ordnance. While the first volume presents the theory and fabrication of SQUIDs, the second volume is devoted to applications. It starts with an important aspect of the analysis of measured magnetic signals generated by current sources (the inverse problem), and includes several chapters devoted to various areas of application, namely biomagnetism (research on and diagnostics of human brain, heart, liver, etc.), detection of extremely weak signals, for example electromagnetic radiation and Nuclear Magnetic Resonance. The volume closes with a chapter on motion detectors and the detection of gravity waves.

Book Novel Techniques and Phenomena in Low static Field NMR and MRI Detected with a SQUID

Download or read book Novel Techniques and Phenomena in Low static Field NMR and MRI Detected with a SQUID written by SeungKyun Lee and published by . This book was released on 2005 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Remote Detection for More Sensitive NMR and MRI

Download or read book Remote Detection for More Sensitive NMR and MRI written by Juliette Anne Seeley and published by . This book was released on 2004 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Visualizing Chemistry

    Book Details:
  • Author : National Research Council
  • Publisher : National Academies Press
  • Release : 2006-06-01
  • ISBN : 030916463X
  • Pages : 222 pages

Download or read book Visualizing Chemistry written by National Research Council and published by National Academies Press. This book was released on 2006-06-01 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists and engineers have long relied on the power of imaging techniques to help see objects invisible to the naked eye, and thus, to advance scientific knowledge. These experts are constantly pushing the limits of technology in pursuit of chemical imagingâ€"the ability to visualize molecular structures and chemical composition in time and space as actual events unfoldâ€"from the smallest dimension of a biological system to the widest expanse of a distant galaxy. Chemical imaging has a variety of applications for almost every facet of our daily lives, ranging from medical diagnosis and treatment to the study and design of material properties in new products. In addition to highlighting advances in chemical imaging that could have the greatest impact on critical problems in science and technology, Visualizing Chemistry reviews the current state of chemical imaging technology, identifies promising future developments and their applications, and suggests a research and educational agenda to enable breakthrough improvements.

Book A Text Book of Medical Instruments

Download or read book A Text Book of Medical Instruments written by S. Ananthi and published by New Age International. This book was released on 2006 with total page 15 pages. Available in PDF, EPUB and Kindle. Book excerpt: About the Book: This book has therefore subdivided the realm of medical instruments into the same sections like a text on physiology and introduces the basic early day methods well, before dealing with the details of present day instruments currently in

Book Magnetic Resonance Neurography

Download or read book Magnetic Resonance Neurography written by Chhabra Avneesh and published by JAYPEE BROTHERS PUBLISHERS. This book was released on 2012-12-15 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, first of its kind, combination of concise explanations and focused clinical information satisfies the needs of practicing radiologists, neurologists, neurosurgeons, plastic and other peripheral nerve surgeons in need of a handy reference and technologists performing MRN studies. Written by two experts of magnetic resonance neurography (MRN) practitioners and educators, this thoroughly illustrated resource delivers how the information you need to perform and interpret peripheral nerve MR imaging studies with confidence. Concise descriptions and high quality illustrations combined wit.