Download or read book Nitric Oxide in the Kidney written by Jennifer M. Sasser and published by Biota Publishing. This book was released on 2015-05-01 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitric oxide (NO) is a key regulator of various cellular signaling pathways throughout the body and plays an important role in renal function under normal physiological and pathophysiological conditions. NO plays a major role in the regulation of renal hemodynamics, tubuloglomerular feedback, sodium transport in the nephron, pressure natriuresis, and renal fibrosis and injury; moreover, a deficiency in NO is characteristic of chronic kidney disease in both human patients and in experimental animal models. The goal of this book is to highlight the actions of NO within the kidney and its effects on the regulation of renal blood flow and tubular transport.
Download or read book Nitric Oxide and the Kidney written by Michael S. Goligorsky and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: A number of remarkable recent breakthroughs have made the study of nitric oxide one of the most exciting fields in physiology and pathophysiology. This authoritative edited volume reviews the progress to date and opens perspectives to novel diagnostic and therapeutic strategies. The contributors are leading authorites, in most cases the investigators who have pioneered the ideas explored in the book.
Download or read book Nitric Oxide and the Kidney written by Sharma S. Prabhakar and published by . This book was released on 2004 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Evaluation of Inducible Nitric Oxide Synthase Inhibition on Kidney Function and Structure in High fat Diet induced Kidney Disease written by and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nitric Oxide and Kidney Function written by David Mattson and published by . This book was released on 2012-06-01 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nitric Oxide Signaling in the Kidney written by Chaojie Zhang and published by . This book was released on 2000 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Role of Nitric Oxide NO and Regulation of NO Synthesis in the Kidney written by Agnes Roczniak and published by . This book was released on 1999 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Statins and Nitric Oxide in Chronic Kidney Disease written by Frank Holden Mose and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nitric Oxide peroxynitrite Balance in Kidney written by Xiaoyan Huang and published by . This book was released on 2008 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Macula Densa Derived Nitric Oxide and Kidney Function written by Anna Ollerstam and published by Uppsala Universitet. This book was released on 2002 with total page 47 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Effect of Diet on Nitric Oxide Synthase Expression in the Kidney of Diabetic Rats written by and published by . This book was released on 2012 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt: Type-2 diabetes affects approximately 8% of all Americans and is the leading cause of kidney disease in the United States. Consumption of diets containing excessive fat and/or fructose are potential risk factors for type-2 diabetes development. Interestingly fat and fructose affect different signaling mechanisms to raise blood glucose levels. Previous studies in our lab have suggested that diet will cause a decreased expression of NOS1 in rats fed a high fructose diet; moreover, knocking out three isoforms of nitric oxide synthase (NOS1, NOS2, and NOS3) leads to kidney problems and other symptoms of diabetes development. It is hypothesized that both high fat and high fructose diets will cause misregulation of NOS1, NOS2, and NOS3 expression in the kidney. To test this Sprague Dawley Rats were fed either a 60% fat diet or a 66% fructose diet for 10 or 12 weeks respectively. RNA was harvested from kidney tissues and real-time PCR was utilized to compare the amount of NOS1, NOS2 or NOS3 RNA in animals fed control diets versus high fat or high fructose diets. While we were unable to detect NOS2 in the kidney samples, NOS1 expression was down regulated to 36.06% ± 36.41% of controls in high fructose fed animals and NOS3 transcription was increased to 141.94% ± 88.75% in high fructose fed rats. Preliminary data in high fat fed rats suggest that NOS1 will be decreased to 61.24% ± 17.11% and NOS3 expression will decrease to 75.18% ± 34.55% of controls. The different diets also induced different trends in regards to weight, glucose, and insulin between the two treatment groups. Differences in NOS1 and NOS3 expression between diets may be due to different signaling mechanisms between the fat and fructose diets causing differences in factors that regulate NOS expression such as glucose, leptin and insulin.
Download or read book Interactions Between Intrarenal Nitric Oxide and the Renin angiotensin System in the Control of Kidney Function and Blood Pressure written by Christine Godfrey Schnackenberg and published by . This book was released on 1996 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Influence of Dietary Salt Intake on Nitric Oxide Synthase Activity in the Rat Kidney microform written by Badri Ahmadi Moridani and published by National Library of Canada = Bibliothèque nationale du Canada. This book was released on 1996 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitric oxide (NO), plays an important role in sodium excretion. The hypothesis that renal nitric oxide synthase (NOS) activity is directly related to salt intake was studied in rats fed low (0.05% NaCI, LSD), normal (0.3%, NSD), or high (8%, HSD) salt diet for 14 days. NOS activity was measured in kidney tissue by conversion of L-$\sp$C-arginine to L-$\sp$C-citrulline. Ca$\sp{2+}$-dependent NOS activity which was 10-20 times higher in the outer and inner medulla compared to cortex was similar in all dietary groups. HSD increased urinary nitrite/nitrate (U$\sb{\rm NOx}$) excretion significantly by 3 days, however no significant differences were observed in NOS activity, serum NOx, or clearance of creatinine. Inhibition of NOS activity in vivo abolished the increase in UNOx excretion seen with HSD, and decreased fractional excretion of sodium. It is concluded that HSD increases NO production by the kidney but this is not due to an induction of NOS enzyme.
Download or read book The Study of Nitric Oxide Synthase Expression Function and Regulation in the Renal Vasculature During Postnatal Renal Development written by Brian Blake Ratliff and published by . This book was released on 2006 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Plasma Total Nitric Oxide and Endothelial Constitutive Nitric Oxide Synthase Ecnos Inron 4 Gene Polymorphism written by Manal F. Elshamaa and published by . This book was released on 2011 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plasma Total Nitric Oxide and Endothelial Constitutive Nitric Oxide Synthase (ecNOS) Inron 4 Gene Polymorphism: A Study in Children with Chronic Kidney Disease.
Download or read book AMP Activated Protein Kinase and Nitric Oxide Synthase Phosphorylation in Kidney and Endothelium written by Peter Francis Mount and published by . This book was released on 2006 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Inducible Nitric Oxide Synthase in Septic Acute Kidney Injury written by Suzanne Heemskerk and published by . This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
