Download or read book Next Generation Nutritional Biomarkers to Guide Better Health Care written by E.E. Baetge and published by Karger Medical and Scientific Publishers. This book was released on 2016-01-14 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are only a few areas in human nutrition and metabolism where biomarkers are routinely used to predict health and functional outcome. For instance, of the four major nutritional deficiencies, only iron deficiency can be precisely diagnosed by employing biomarkers. They therefore play a limited role in research and decision making, and intervention strategies are still mostly targeted at the population level. What is needed at this stage are biomarkers that are predictive of later functional health and that stay stable from infancy to childhood and adult health. Moreover, individual variability must be considered, taking into account the complexity of foods, lifestyle, and metabolic processes that contribute to health or disease. These factors present significant challenges when it comes to personalizing dietary advice for healthy or diseased individuals. This book focuses on the values and limitations of traditional nutritional biomarkers and on opportunities for new biomarkers. Contributions are divided into three parts: Methodologies with regard to global epidemiology; applications/end users, and future horizons. The main goal is to review recent developments and predict how exciting new technologies could be used to drive advances in nutrition-related health care.

Download or read book Preventive Aspects of Early Nutrition written by M.S. Fewtrell and published by Karger Medical and Scientific Publishers. This book was released on 2016-04-18 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is ample evidence that early-life nutrition plays a powerful role in programming a person's development, metabolism and health for the future. Optimizing early nutrition may reduce the risk of cardiovascular diseases, allergies, diabetes and obesity, and positively influence immune function as well as cognitive and behavioral outcomes later in life. The first part of this book covers the impact of nutrition on the immune system, the role of gut microbiota in the immune status, as well as the prevention and management of food allergies in children. The second part is dedicated to obesity prevention: experts in epigenetics and metabolic programming share scientific evidence on the use of biomarkers for predicting the risk of early obesity. They also discuss potential strategies for interrupting intergenerational cycles of obesity during pregnancy, early infancy and childhood. The last part covers complementary feeding and its importance in short- and long-term health, and how it can affect behavioral and psychological aspects, as well as food preferences in later life.

Download or read book Precision Medicine for Investigators Practitioners and Providers written by Joel Faintuch and published by Academic Press. This book was released on 2019-11-16 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Precision Medicine for Investigators, Practitioners and Providers addresses the needs of investigators by covering the topic as an umbrella concept, from new drug trials to wearable diagnostic devices, and from pediatrics to psychiatry in a manner that is up-to-date and authoritative. Sections include broad coverage of concerning disease groups and ancillary information about techniques, resources and consequences. Moreover, each chapter follows a structured blueprint, so that multiple, essential items are not overlooked. Instead of simply concentrating on a limited number of extensive and pedantic coverages, scholarly diagrams are also included. Provides a three-pronged approach to precision medicine that is focused on investigators, practitioners and healthcare providers Covers disease groups and ancillary information about techniques, resources and consequences Follows a structured blueprint, ensuring essential chapters items are not overlooked

Download or read book Guiding Principles for Developing Dietary Reference Intakes Based on Chronic Disease written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-12-21 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since 1938 and 1941, nutrient intake recommendations have been issued to the public in Canada and the United States, respectively. Currently defined as the Dietary Reference Intakes (DRIs), these values are a set of standards established by consensus committees under the National Academies of Sciences, Engineering, and Medicine and used for planning and assessing diets of apparently healthy individuals and groups. In 2015, a multidisciplinary working group sponsored by the Canadian and U.S. government DRI steering committees convened to identify key scientific challenges encountered in the use of chronic disease endpoints to establish DRI values. Their report, Options for Basing Dietary Reference Intakes (DRIs) on Chronic Disease: Report from a Joint US-/Canadian-Sponsored Working Group, outlined and proposed ways to address conceptual and methodological challenges related to the work of future DRI Committees. This report assesses the options presented in the previous report and determines guiding principles for including chronic disease endpoints for food substances that will be used by future National Academies committees in establishing DRIs.

Download or read book Epigenetics in Precision Medicine written by Jose Luis Garcia-Gimenez and published by Elsevier. This book was released on 2021-11-12 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, knowledge of epigenetic mechanisms underlying disease onset and progression has proven crucial for the development of novel early diagnosis and prognosis biomarkers for patient stratification and precision medicine. Epigenetics in Precision Medicine, a new volume in the Translational Epigenetics series, provides a thorough discussion and overview of current developments in clinical epigenetics with special emphasis on epigenetic biomarkers that can be used for clinical diagnosis, prognosis, patient stratification, and treatment monitoring. Disease types discussed include cancer, metabolic disorders, neurodegenerative diseases, bone disease, and immune-related disorders. The book examines the challenges of advancing epigenetics research and translating findings to the clinic and drug discovery in each of these areas, as well as current solutions; chapter authors discuss how to leverage epigenomic technologies, applications, and tools, such as next-generation sequencing, to discover new epigenetic biomarkers in disease and drug studies. Epigenetics in Precision Medicine focuses on complex epigenetic mechanisms in several pathologies, and explores how epigenetics can power the advance of precision medicine, not only by improving in vitro diagnostic and prognostic tools, but by providing new therapeutic approaches to treat human disease. Provides a thorough grounding in epigenetics-driven precision medicine, with emphasis on developing and implementing early diagnosis and prognosis biomarkers, and supporting patient stratification Empowers researchers and clinicians to incorporate epigenetics in new disease research, drug discovery, and clinical practice Features chapter contributions from international leaders in the field

Download or read book Advances in Precision Nutrition Personalization and Healthy Aging written by Alexander G. Haslberger and published by Springer Nature. This book was released on 2022-11-03 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview on current trends and developments in precision nutrition and personalized health preservation, focussing on a field which is undergoing rapid change. Today, personalized strategies contrast generally accepted guidelines for specified groups and improved health and disease markers are shifting health care toward preventive strategies. At the same time, advances in food additives, nutraceuticals, functional, and medical foods are breaking down the traditional domains of health-related disciplines. This book aims to provide an overview on these processes, discusses arising problems, and provides an outlook on the future of personalized health care and the role of precision nutrition. It covers preliminary thoughts on what has been achieved and focusses on developments in the area of metabolic diseases, aging, and neurology. The book is intended as a primer in the field of precision nutrition and is aimed at researchers, clinicians, and students in health-related disciplines, who would like to get insights into current trends and developments in this area

Download or read book Biomarkers in Environmental and Human Health Biomonitoring written by Ritu Mishra and published by Elsevier. This book was released on 2024-06-05 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers in Environmental and Human Health Biomonitoring: An Integrated Perspective provides a holistic view of the biomonitoring of environmental degradation, accumulated toxicity, and associated human health concerns. The book incorporates theoretical and practical aspects of the biomonitoring of environmental pollution and the health surveillance of ecological communities using samples from living organisms which are analyzed for contaminants and toxin levels. In the first half, the book provides a general overview if the different types of biomarkers, their significance as bioindicators for contaminants and detection of toxicity, as well as how they can be utilized in the restoration of degraded ecosystems. The second half of the book discusses molecular biomarkers and how they are used as diagnostic and prognostic tools for pollution monitoring. It also reviews analytical tools used to validate the biomarkers in the detection and monitoring of pollution and disease. Finally, the book delves into how novel approaches like genetic ecotoxicology; Big Data, and artificial intelligence calculates the potential consequences of environmental pollution on the ecosystems and on human health. Covers the fundamentals, types, significance, and limitations of biomarkers Examines various types of plants, animals, and secondary metabolites in identifying and monitoring toxicity in different ecosystems and potential impacts on health Reviews biomarker-based and bioinformatic tools in the detection and monitoring of environmental pollution and associated human health

Download or read book Doing Nutrition Differently written by Allison Hayes-Conroy and published by Routledge. This book was released on 2016-05-13 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Hegemonic nutrition' is produced and proliferated by a wide variety of social institutions such as mainstream nutrition science, clinical nutrition as well as those less classically linked such as life science/agro-food companies, the media, family, education, religion and the law. The collective result is an approach to and practice of nutrition that alleges not only one single, clear-cut and consented-upon set of rules for 'healthy eating,' but also tacit criteria for determining individual fault, usually some combination of lack of education, motivation, and unwillingness to comply. Offering a collection of critical, interdisciplinary replies and responses to the matter of 'hegemonic nutrition' this book presents contributions from a wide variety of perspectives; nutrition professionals and lay people, academics and activists, adults and youth, indigenous, Chicana/o, Latina/o, Environmentalist, Feminist and more. The critical commentary collectively asks for a different, more attentive, and more holistic practice of nutrition. Most importantly, this volume demonstrates how this 'new' nutrition is actually already being performed in small ways across the American continent. In doing so, the volume empowers diverse knowledges, histories, and practices of nutrition that have been marginalized, re-casts the objectives of dietary intervention, and most broadly, attempts to revolutionize the way that nutrition is done.

Download or read book The Detection of Biomarkers written by Sibel A. Ozkan and published by Academic Press. This book was released on 2021-12-05 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reliable, precise and accurate detection and analysis of biomarkers remains a significant challenge for clinical researchers. Methods for the detection of biomarkers are rather complex, requiring pre-treatment steps before analysis can take place. Moreover, comparing various biomarker assays and tracing research progress in this area systematically is a challenge for researchers. The Detection of Biomarkers presents developments in biomarker detection, including methods tools and strategies, biosensor design, materials, and applications. The book presents methods, materials and procedures that are simple, precise, sensitive, selective, fast and economical, and therefore highly practical for use in clinical research scenarios. This volume situates biomarker detection in its research context and sets out future prospects for the area. Its 20 chapters offer a comprehensive coverage of biomarkers, including progress on nanotechnology, biosensor types, synthesis, immobilization, and applications in various fields. The book also demonstrates, for students, how to synthesize and immobilize biosensors for biomarker assay. It offers researchers real alternative and innovative ways to think about the field of biomarker detection, increasing the reliability, precision and accuracy of biomarker detection. Locates biomarker detection in its research context, setting out present and future prospects Allows clinical researchers to compare various biomarker assays systematically Presents new methods, materials and procedures that are simple, precise, sensitive, selective, fast and economical Gives innovative biomarker assays that are viable alternatives to current complex methods Helps clinical researchers who need reliable, precise and accurate biomarker detection methods

Download or read book Metabolic Issues of Clinical Nutrition written by Simon P. Allison and published by Karger Medical and Scientific Publishers. This book was released on 2004-01-01 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: As widely spread health problems related to over-and undernutrition have grown nowadays to an epidemic extent and even prevail over infectious diseases, a better knowledge of the metabolic basis of clinical nutrition has become essential. The extremes of the nutritional spectrum, undernutrition and obesity, are no longer considered as isolated opposites with different effects on separate risk groups, but paradoxically prove to be interacting in a setting of rapidly changing lifestyles, as is presently the case worldwide. Recurring issues such as insulin resistance, changes in intermediary metabolism, fluid and electrolyte physiology, genetic and non-genetic inheritance are highlighted, as well as the biological linkage between maternal undernutrition and the development of obesity, diabetes and cardiovascular disease in later life. The problems at stake present a new and enormous challenge for future healthcare policies and, therefore, are better tackled today. This book will be an interesting source of knowledge for internists, family physicians, pediatricians, dieticians, endocrinologists, gastroenterologists, and public health officers.

Download or read book Cancer New Insights for the Healthcare Professional 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-10 with total page 3786 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Cancer. The editors have built Cancer: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cancer in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cancer: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book A Comprehensive Guide to Toxicology in Nonclinical Drug Development written by Ali S. Faqi and published by Elsevier. This book was released on 2024-02-11 with total page 1074 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Third Edition is a valuable reference providing a complete understanding of all aspects of nonclinical toxicology in pharmaceutical research. This updated edition has been expanded and re-developed covering a wide-range of toxicological issues in small molecules and biologics. Topics include ADME in drug discovery, pharmacokinetics, toxicokinetics, formulations, and genetic toxicology testing. The book has been thoroughly updated throughout to reflect the latest scientific advances and includes new information on antiviral drugs, anti-diabetic drugs, immunotherapy, and a discussion on post-pandemic drug development challenges and opportunities. This is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. Provides updated, unique content not covered in one comprehensive resource, including chapters on stem cells, antiviral drugs, anti-diabetic drugs, and immunotherapy Includes the latest international guidelines for nonclinical toxicology in both small and large molecules Incorporates practical examples in order to illustrate day-to-day activities and expectations associated with working in nonclinical toxicology

Download or read book Genomics An Issue of Nursing Clinics written by Stephen D. Krau and published by Elsevier Health Sciences. This book was released on 2013-12-28 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Nursing Clinics of North America is Guest Edited by Stephen D. Krau, PhD, RN, CNE, from Vanderbilt University and will focus on genomics. Article topics will include Genetic and Genomic Testing, Integrating Genomics into Research, Genomic Assessments and Interventions in Psychiatric Nursing Practice, Genomics in Critical Care, Cardiomyopathy and Genetics, Genetics and Chronic Diseases, Genomics and Patients with Rare Chronic Diseases, Epigenetics and the implications for disease processes, Impact of Genetics on Oncology Nursing, and Pharmacogenetics.

Download or read book Nomination of Lester M Crawford written by United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions and published by . This book was released on 2005 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Dietitian s Guide to Vegetarian Diets written by Reed Mangels and published by Jones & Bartlett Learning. This book was released on 2004 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Dietitians Guide to Vegetarian Diets, Second Edition highlights the trends and research on vegetarian diets and provides practical ideas in the form of counseling points to help dietitians and other health care providers convey information to their clients. The text presents vital information on vegetarian nutritional needs, healthier and more satisfying diets, and guidelines for treating clients of all ages and clients with special considerations, such as pregnant women, athletes, and diabetics.

Download or read book Advances in Food Diagnostics written by Fidel Toldrá and published by John Wiley & Sons. This book was released on 2017-06-26 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Still the most up-to-date, comprehensive, and authoritative book on food diagnostics available Featuring seven entirely new chapters, the second edition of this critically acclaimed guide has been extensively revised and updated. Once again delivering food professionals the latest advances in food diagnostics and analysis, the book approaches the topic in several different ways: reviewing novel technologies to evaluate fresh products; describing and analysing in depth specific modern diagnostics; providing analyses of data processing; and discussing global marketing, with insights into future trends. Written by an international team of experts, this volume not only covers most conventional lab-based analytical methods, but also focuses on leading-edge technologies which are being or are about to be introduced. Advances in Food Diagnostics, Second Edition: Covers ultrasound, RMN, chromatography, electronic noses, immunology, GMO detection and microbiological and molecular methodologies for rapid detection of pathogens Explores the principles and applications of immunodiagnostics in food safety and the use of molecular biology to detect and characterize foodborne pathogens Includes DNA-based and protein-based technologies to detect and identify genetically-modified food or food components Focuses on the translation of diagnostics tests from bench to the market in order to illustrate the benefits to the food industry Provides an overview of the business end of food diagnostics; identifying the markets, delineating the sellers and the buyers, comparing current technology with traditional methods, certifying operations and procedures, and analysing diagnostic devices within the food and related industries This is an indispensable resource for food scientists, food quality analysts, food microbiologists and food safety professionals. It also belongs on the reference shelves of labs conducting food diagnostics for the analysis of the sensory, quality and safety aspects of food.

Download or read book Journey to Zero written by Rubin Pillay MD PhD and published by Xlibris Corporation. This book was released on 2023-11-19 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: In "Journey to Zero: Digital Technology's Quest for Perfect Healthcare," author Rubin Pillay presents a visionary exploration of how digital technology can revolutionize the healthcare industry, leading us towards a future of sustainable and impactful healthcare delivery. With a comprehensive and insightful approach, this book uncovers the potential of digital health to achieve seven transformative "zeros" in healthcare. Drawing on extensive research and real-world examples, Rubin Pillay introduces the concept of the seven zeros - Zero Exclusion, Zero Wait Time, Zero Harm, Zero Cost, Zero Waste, Zero Disparities, and Zero Carbon Emissions. Each zero represents a critical aspect of healthcare transformation, highlighting the power of digital health to create positive change in these areas. From breaking down barriers to access and ensuring no one is left behind (Zero Exclusion), to eliminating unnecessary waiting times and providing instant access to care (Zero Wait Time), this book delves into the innovative solutions and strategies that can reshape healthcare delivery. Furthermore, it explores the potential of digital health to enhance patient safety, reduce costs, and improve efficiency, ultimately striving for the ultimate goal of zero harm and zero cost. But the impact of digital health goes beyond just improving patient care. "Journey to Zero Digital Technology's Quest for Perfect Healthcare" demonstrates how digital technologies can minimize waste, eliminate disparities in healthcare, and even help achieve zero carbon emissions, contributing to a sustainable and environmentally conscious healthcare system. Accessible yet thought-provoking, this book serves as a guiding light for healthcare professionals, policymakers, and technology enthusiasts who seek to understand the transformative potential of digital health. Rubin Pillay masterfully navigates the complexities of this rapidly evolving field, presenting practical insights, ethical considerations, and a compelling vision for the future of healthcare. In " Journey to Zero Digital Technology's Quest for Perfect Healthcare” Rubin Pillay provides an enlightening roadmap towards a healthcare system that is inclusive, efficient, cost-effective, and environmentally sustainable. It challenges us to embrace the power of digital health and work towards achieving the seven zeros, ultimately creating a healthcare landscape that benefits us all. Rubin Pillay brings together expertise, innovation, and a passion for improving healthcare to inspire readers to join the digital health revolution. Are you ready to embark on this transformative journey towards a future of sustainable and impactful healthcare?