Download or read book New Transcription Factors and Their Role in Diabetes and Therapy written by Jacob E. Friedman and published by Elsevier. This book was released on 2006-08-10 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains contributions from some of the most eminent experts in the fields of genetics, biochemistry, and pathophysiology of diabetes. Through specific examples, with broad applications, this book provides a comprehensive look at how transcription factors may underline the pathogenetic mechanisms of diabetes and obesity. Volume 5 provides an overview of the status of the field, while also providing valuable information of practical utility to those who do not necessarily work in this field. The integration of basic biology with physiologically and clinically relevant proteins should provide the reader with a theoretical background to understanding the strategies for new potential therapeutic targets and their application to disease. *Applies molecular biology to transcriptional regulation of metabolism and obesity*Underscores the clinical relevance of transcription factors*Provides a valuable overview of the current status of the field

Download or read book Diabetes Mellitus in Children written by Mark A. Sperling and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Genetic Landscape of Diabetes written by Laura Dean and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Diabetes and Hypertension written by Samy I. McFarlane and published by Springer Science & Business Media. This book was released on 2012-10-19 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes and hypertension have evolved as two of the modern day epidemics affecting millions of people around the world. These two common co-morbidities lead to substantial increase in cardiovascular disease, the major cause of morbidity and mortality of adults around the world. In Diabetes and Hypertension: Evaluation and Management, a panel of renowned experts address a range of critical topics -- from basic concepts in evaluation and management of diabetes and hypertension, such as dietary interventions, to evaluation and management of secondary hypertension in clinical practice. Other chapters focus on high cardiovascular risk populations such as those with coronary heart disease, chronic kidney disease and minority patients. In addition, evolving concepts and new developments in the field are presented in other chapters, such as prevention of type 2 diabetes and the epidemic of sleep apnea and its implication for diabetes and hypertension evaluation and management. An important title covering two of the most troubling disorders of our time, Diabetes and Hypertension: Evaluation and Management will provide the busy practitioner with cutting edge knowledge in the field as well as practical information that can translate into better care provided to the high-risk population of diabetics and hypertensive patients.

Download or read book Stress Activated Protein Kinases written by Francesc Posas and published by Springer Science & Business Media. This book was released on 2008-01-24 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book leading researchers in the field discuss the state-of-the-art of many aspects of SAPK signaling in various systems from yeast to mammals. These include various chapters on regulatory mechanisms as well as the contribution of the SAPK signaling pathways to processes such as gene expression, metabolism, cell cycle regulation, immune responses and tumorigenesis. Written by international experts, the book will appeal to cell biologists and biochemists.

Download or read book Frontiers in Medicinal Chemistry written by Atta-ur- Rahman and published by Bentham Science Publishers. This book was released on 2010-12-10 with total page 715 pages. Available in PDF, EPUB and Kindle. Book excerpt: ""Frontiers in Medicinal Chemistry" is an Ebook series devoted to the review of areas of important topical interest to medicinal chemists and others in allied disciplines. "Frontiers in Medicinal Chemistry" covers all the areas of medicinal chemistry, incl"

Download or read book Chromatin Proteins and Transcription Factors as Therapeutic Targets written by and published by Academic Press. This book was released on 2017-02-17 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chromatin Proteins and Transcription Factors as Therapeutic Targets, the latest volume in the Advances in Protein Chemistry and Structural Biology series is an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics. Provides cutting-edge developments in the field Contains chapters written by authorities Targeted to a wide audience of researchers, specialists, and students

Download or read book Stem Cell Therapy for Diabetes written by Shimon Efrat and published by Springer Science & Business Media. This book was released on 2009-12-01 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cell Therapy for Diabetes, one of the latest installments of the Stem Cell Biology and Regenerative Medicine series, reviews the three main approaches for generation of sufficient numbers of insulin-producing cells for restoration of an adequate beta-cell mass: beta-cell expansion, stem-cell differentiation, and nuclear reprogramming. Adeptly collecting the research of the leading scientists in the field, Stem Cell Therapy for Diabetes compares the merits of employing autologous versus banked allogeneic cell sources for generation of surrogate beta cells, and addresses tissue engineering and ways for cell protection from recurring autoimmunity and graft rejection. Stem Cell Therapy for Diabetes provides essential reading for those especially interested in tracking the progress in applying of one of the most exciting new developments in bio-medicine towards a cure for diabetes.

Download or read book Mitochondria in Obesity and Type 2 Diabetes written by Beatrice Morio and published by Academic Press. This book was released on 2019-04-26 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases synthesizes discoveries from laboratories around the world, enhancing our understanding of the involvement of mitochondria in the etiology of diseases, such as obesity and type 2 diabetes. Chapters illustrate and provide an overview of key concepts on topics such as the role of mitochondria in adipose tissue, cancer, cardiovascular comorbidities, skeletal muscle, the liver, kidney, and more. This book is a must-have reference for students and educational teams in biology, physiology and medicine, and researchers. Synthesizes actual knowledge on mitochondrial function Provides an integrated vision of each tissue in the etiology of obesity and type 2 diabetes Identifies the interactive networks that involve alteration in mitochondrial mass and function in disease progression Highlights the role played by mitochondria in the prevention and treatment of obesity and type 2 diabetes

Download or read book International Textbook of Diabetes Mellitus written by R. A. De Fronzo and published by John Wiley & Sons. This book was released on 2004-06-25 with total page 2073 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition is the most comprehensive reference on both the clinical and scientific aspects of diabetes, and is truly global in perspective with the inclusion of epidemiology and the nature and care of diabetes in different parts of the world. Following a similar format to the previous editions, the primary philosophy of the book is to comprehensively cover the basic science of metabolism, linking this closely to the pathophysiology and clinical aspects of the disease. A valuable resource for the whole diabetes community, the new edition offers: * Fully revised, updated and expanded chapters * Comprehensive coverage of all aspects of diabetes * 116 extensively referenced chapters * Full colour throughout * Available in print and online The International Textbook of Diabetes Mellitus, Third Edition is also available online via Wiley InterScience. With the flexibility afforded by the powerful search and navigation capabilities of Wiley InterScience, you can search the Textbook by subject, article and keyword. New and revised articles added regularly ensure that both professionals and students working within diabetes are kept abreast of rapidly developing areas such as genetics, treatment and epidemiology. This excellent work is an essential reference tool for all members of diabetes and endocrine teams, medical students, medical schools and libraries, and provides a valuable resource for pharmaceutical companies and industries which have an interest in this important field. FROM REVIEWS OF THE SECOND EDITION: "The scope is extraordinarily wide and truly international...a must for all libraries and any individuals who are seriously interested in the diabetes epidemic..." (Diabetologia) "...a cornerstone in the field of diabetes..." (The European Journal of Medicine) "...This multi-authored textbook provides a wealth of information spanning virtually all aspects of diabetes..." (Trends in Endocrinology and Metabolism)

Download or read book Transcription Factors in Immunological Disease and Haematological Malignancies written by Tomokatsu Ikawa and published by Frontiers Media SA. This book was released on 2024-02-23 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transcription factors are nuclear proteins that control the rate of gene expression, activating or repressing transcription in a context-dependent manner. These regulators lie at the heart of most cell fate decisions of immune cells, guiding the initiation and maintenance of lineage identity and controlling the cell-type-specific gene expression that underpins the unique functions of each immune cell lineage. As such transcription factors are of critical importance for a healthy immune system, with mutation of specific factors leading to immune dysregulation with immunodeficiency and autoimmunity. In addition, perturbation of transcription factors known to regulate immune cell function have been implicated in the genesis of haematological malignancies through chromosomal translocation, over-expression or genetic deletion.

Download or read book Otologic Trauma Pathology and Therapy written by Lukas D. Landegger and published by Frontiers Media SA. This book was released on 2022-05-04 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Diabetic Angiopathies Advances in Research and Treatment 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetic Angiopathies—Advances in Research and Treatment: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Diabetic Angiopathies in a concise format. The editors have built Diabetic Angiopathies—Advances in Research and Treatment: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diabetic Angiopathies in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Diabetic Angiopathies—Advances in Research and Treatment: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book Oxidative Stress Antioxidants Transcription Factors and Assimilation of Signal Transduction Pathways in Obesity Related Disorders written by Terry D. Hinds, Jr and published by Frontiers Media SA. This book was released on 2021-10-21 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topic Editors Terry Hinds and David Stec have submitted patents related to bilirubin and obesity related disorders. The other Topic Editor declare no potential conflicts of interest with regards to the Research Topic subject.

Download or read book Mechanisms of Insulin Action written by Alan R. Saltiel and published by Springer Science & Business Media. This book was released on 2007-10-05 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. It explores insulin action at the most basic levels, through complex systems.

Download or read book The Challenge of New Therapeutic Approaches for Unmet Therapeutic Needs written by Arianna Carolina Rosa and published by Frontiers Media SA. This book was released on 2020-12-18 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Download or read book Role of C EBPalpha Phosphorylation in Regulation of Gene Expression and Metabolism written by Hyuk C. Cha and published by . This book was released on 2006 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: