Download or read book New Technologies for Detection Monitoring and Treatment of Parkinson s Disease written by Martin J. McKeown and published by Frontiers Media SA. This book was released on 2020-07-22 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book New Technologies for Detection Monitoring and Treatment of Parkinson s Disease written by Martin J. McKeown and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Download or read book Intelligent Technologies and Parkinson s Disease Prediction and Diagnosis written by Kumar, Abhishek and published by IGI Global. This book was released on 2024-02-08 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: When it comes to Parkinson's disease, one of the most important issues revolves around early detection and accurate diagnosis. The intricacies of this neurodegenerative disorder often elude timely identification, leaving patients and healthcare providers grappling with its progressive symptoms. Ethical concerns surrounding the use of machine learning to aid in diagnosis further complicate this challenge. This issue is particularly significant for research scholars, PhD fellows, post-doc fellows, and medical and biomedical scholars seeking to unravel the mysteries of Parkinson's disease and develop more effective treatments. Intelligent Technologies and Parkinson’s Disease: Prediction and Diagnosis serves as a beacon of hope in the quest to revolutionize Parkinson's disease diagnosis and treatment. It unveils the remarkable potential of artificial intelligence (AI) and machine learning (ML) in remodeling the way we approach this debilitating condition. With a comprehensive exploration of AI's capacity to analyze speech patterns, brain imaging data, and gait patterns, this book offers a powerful solution to the challenges of early detection and accurate diagnosis.

Download or read book New Advanced Wireless Technologies for Objective Monitoring of Motor Symptoms in Parkinson s Disease written by Antonio Suppa and published by Frontiers Media SA. This book was released on 2018-04-27 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, a growing number of researchers have used advanced wireless technologies including wearable sensors for objective evaluation of specific motor symptoms in patients with Parkinson's disease (PD). In the near future, sensing technologies will likely provide relevant advances in the clinical management of patients with PD, contributing to early diagnosis, disease progression monitoring and therapeutic approach. In this regard, this eBook hosts new original studies focused on the objective monitoring of motor symptoms and therapeutic perspectives of wireless technologies in patients with PD.

Download or read book Parkinson s Disease Management through ICT written by Joan Cabestany and published by CRC Press. This book was released on 2022-09-01 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parkinson's Disease (PD) is a neurodegenerative disorder that manifests with motor and non-motor symptoms. PD treatment is symptomatic and tries to alleviate the associated symptoms through an adjustment of the medication. As the disease is evolving and this evolution is patient specific, it could be very difficult to properly manage the disease.The current available technology (electronics, communication, computing, etc.), correctly combined with wearables, can be of great use for obtaining and processing useful information for both clinicians and patients allowing them to become actively involved in their condition.Parkinson's Disease Management through ICT: The REMPARK Approach presents the work done, main results and conclusions of the REMPARK project (2011 – 2015) funded by the European Union under contract FP7-ICT-2011-7-287677. REMPARK system was proposed and developed as a real Personal Health Device for the Remote and Autonomous Management of Parkinson’s Disease, composed of different levels of interaction with the patient, clinician and carers, and integrating a set of interconnected sub-systems: sensor, auditory cueing, Smartphone and server. The sensor subsystem, using embedded algorithmics, is able to detect the motor symptoms associated with PD in real time. This information, sent through the Smartphone to the REMPARK server, is used for an efficient management of the disease.

Download or read book New Advanced Wireless Technologies for Objective Monitoring of Motor Symptoms in Parkinson s Disease written by and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, a growing number of researchers have used advanced wireless technologies including wearable sensors for objective evaluation of specific motor symptoms in patients with Parkinson's disease (PD). In the near future, sensing technologies will likely provide relevant advances in the clinical management of patients with PD, contributing to early diagnosis, disease progression monitoring and therapeutic approach. In this regard, this eBook hosts new original studies focused on the objective monitoring of motor symptoms and therapeutic perspectives of wireless technologies in patients with PD.

Download or read book Neuroscience Trials of the Future written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-11-07 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt: On March 3-4, 2016, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop in Washington, DC, bringing together key stakeholders to discuss opportunities for improving the integrity, efficiency, and validity of clinical trials for nervous system disorders. Participants in the workshop represented a range of diverse perspectives, including individuals not normally associated with traditional clinical trials. The purpose of this workshop was to generate discussion about not only what is feasible now, but what may be possible with the implementation of cutting-edge technologies in the future.

Download or read book A Holter for Parkinson s Disease Motor Symptoms STAT On TM written by Joan Cabestany and published by River Publishers Series in Biotechnology and Medical Research. This book was released on 2023-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the experience following from the achieved results in the REMPARK project on Parkinson's Disease management up to the launch of a new medical product to the European market, STAT-ONTM.

Download or read book Mobile Solutions and Their Usefulness in Everyday Life written by Sara Paiva and published by Springer. This book was released on 2018-12-11 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an insight into recent technological trends and innovations in solutions and platforms to improve mobility of visually impaired people. The authors’ goal is to help to contribute to the social and societal inclusion of the visually impaired. The book’s topics include, but are not limited to, obstacle detection systems, indoor and outdoor navigation, transportation sustainability systems, and hardware/devices to aid visually impaired people. The book has a strong focus on practical applications tested in a real environment. Applications include city halls, municipalities, and companies that must keep up to date with recent trends in platforms, methodologies and technologies to promote urban mobility. Also discuss are broader realms including education, health, electronics, tourism, and transportation. Contributors include a variety of researchers and practitioners around the world.

Download or read book Digital Technologies in Movement Disorders written by and published by Elsevier. This book was released on 2023-07-21 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Digital Technologies in Movement Disorders, Volume Five updates on the latest advances in new technologies for the care of common conditions, including Parkinson's disease and other diseases. The book has been organized in four differentiated sections with chapters that cover an Introduction, key concepts, and overview of digital solutions, Applications of AI in MD, Digital Biomarkers in MD, Sensors basic concepts for the MD specialist, Wearable systems in MD, Quantitative gait analysis, The challenges and opportunities of remote evaluation in MD, Telemedicine in MD, ePROs, eCOA and other digital health solutions, HIFU, Telerrehabilition and other therapeutical applications of technology, and more.

Download or read book Techniques for Assessment of Parkinsonism for Diagnosis and Rehabilitation written by Sridhar P. Arjunan and published by Springer Nature. This book was released on 2021-08-02 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the range of technologies that have been developed for diagnosing and assessing Parkinson’s disease patients. Also presenting the latest studies providing insights into the changes to the neural system in Parkinson’s disease, it is a valuable resource for neurologists, general practitioners and nurses. Further, the book highlights areas that require more research, and as such will appeal to researchers, biomedical engineers and clinicians.

Download or read book Levodopa pharmacokinetics from stomach to brain written by Maria Nord and published by Linköping University Electronic Press. This book was released on 2019-01-07 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parkinson’s disease (PD) is one of the most common neurodegenerative disorders and it is caused by a loss of dopamine (DA) producing neurons in the basal ganglia in the brain. The PD patient suffers from motor symptoms such as tremor, bradykinesia and rigidity and treatment with levodopa (LD), the precursor of DA, has positive effects on these symptoms. Several factors affect the availability of orally given LD. Gastric emptying (GE) is one factor and it has been shown to be delayed in PD patients resulting in impaired levodopa uptake. Different enzymes metabolize LD on its way from the gut to the brain resulting in less LD available in the brain and more side effects from the metabolites. By adding dopa decarboxylase inhibitors (carbidopa or benserazide) or COMT-inhibitors (e.g. entacapone) the bioavailability of LD increases significantly and more LD can pass the blood-brain-barrier and be converted to DA in the brain. It has been considered of importance to avoid high levodopa peaks in the brain because this seems to induce changes in postsynaptic dopaminergic neurons causing disabling motor complications in PD patients. More continuously given LD, e.g. duodenal or intravenous (IV) infusions, has been shown to improve these motor complications. Deep brain stimulation of the subthalamic nucleus (STN DBS) has also been proven to improve motor complications and to make it possible to reduce the LD dosage in PD patients. In this doctoral thesis the main purpose is to study the pharmacokinetics of LD in patients with PD and motor complications; in blood and subcutaneous tissue and study the effect of GE and PD stage on LD uptake and the effect of continuously given LD (CDS) on LD uptake and GE; in blood and cerebrospinal fluid (CSF) when adding the peripheral enzyme inhibitors entacapone and carbidopa to LD infusion IV; in brain during STN DBSand during oral or IV LD treatment. To conclude, LD uptake is more favorable in PD patients with less severe disease and GE is delayed in PD patients. No obvious relation between LD uptake and GE or between GE and PD stage is seen and CDS decreases the LD levels. Entacapone increases the maximal concentration of LD in blood and CSF. This is more evident with additional carbidopa and important to consider in avoiding high LD peaks in brain during PD treatment. LD in brain increases during both oral and IV LD treatment and the DA levels follows LD well indicating that PD patients still have capacity to metabolize LD to DA despite probable pronounced nigral degeneration. STN DBS seems to increase putaminal DA levels and together with IV LD treatment also increases LD in brain possibly explaining why it is possible to decrease LD medication after STN DBS surgery. Parkinsons sjukdom (PS) är en av de vanligaste s.k. neurodegenerativasjukdomarna och orsakas av förlust av dopamin(DA)producerande nervceller i hjärnan. Detta orsakar motoriska symptom såsom skakningar, stelhet och förlångsammade rörelser. Levodopa (LD) är ett ämne, som kan omvandlas till DA i hjärnan och ge symptomlindring och det är oftast förstahandsval vid behandling av patienter med PS. Flera faktorer påverkar tillgängligheten av LD, bl.a. den hastighet som magsäcken tömmer sig med och denna verkar förlångsammad hos personer med PS vilket ger sämre tillgänglighet av LD i blodet och därmed i hjärnan. LD bryts även ner i hög grad av olika enzym ute i kroppen vilket leder till mindre mängd LD som hamnar i hjärnan och till fler nedbrytningsprodukter som orsakar biverkningar. Tillägg av enzymhämmare leder till ökad mängd LD som kan nå hjärnan och omvandlas till DA. Det anses viktigt att undvika höga toppar av LD i hjärnan då dessa verkar bidra till utvecklandet av besvärliga motoriska komplikationer hos patienter med PS. Om LD ges mer kontinuerligt, exempelvis som en kontinuerlig infusion in i tarmen eller i blodet, så minskar dessa motoriska komplikationer. Inopererande av stimulatorer i vissa delar av hjärnan (DBS) har också visat sig minska dessa motoriska komplikationer och även resultera i att man kan minska LD-dosen. Huvudsyftet med den här avhandlingen är att studera LD hos patienter med PS; i blod och fettvävnad då LD ges i tablettform och se om det finns något samband med LD-upptag och hastigheten på magsäckstömningen (MT) och om kontinuerligt given LD påverkar LD-upptaget eller MT; i blod och i ryggmärgsvätska då enzymhämmarna entakapon och karbidopa tillsätts LD; i hjärna vid behandling med DBS och då LD ges både som tablett och som infusion i blodet. Sammanfattningsvis kan vi se att LD-upptaget är mer gynnsamt hos patienter med PS i tidigare skede av sjukdomens komplikationsfas. MT är förlångsammad hos patienter med PS och det är inget tydligt samband mellan LD-upptag och MT eller mellan MT och sjukdomsgrad. Kontinuerligt given LD minskar LDnivåerna. Enzymhämmaren entakapon ökar den maximala koncentrationen av LD i blod och ryggmärgsvätska och effekten är mer tydlig vid tillägg av karbidopa vilket är viktigt att ta i beaktande vid behandling av PS för att undvika höga toppar av LD i hjärnan. LD ökar i hjärnan då man behandlar med LD i tablettform och som infusion i blodet och DA-nivåerna i hjärnan följer LD väl vilket visar på att patienter med PS fortfarande kan omvandla LD till DA trots trolig uttalad brist av de DA-producerande nervcellerna i hjärnan. DBS verkar öka DA i vissa områden i hjärnan och tillsammans med LD-infusion i blodet verkar det även öka LD i hjärnan och det kan förklara varför man kan sänka LDdosen efter DBS-operation.

Download or read book Parkinson s Disease written by National Collaborating Centre for Chronic Conditions (Great Britain) and published by Royal College of Physicians. This book was released on 2006 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book An Essay on the Shaking Palsy written by James Parkinson and published by . This book was released on 1817 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Movement Disorders Curricula written by Cristian Falup-Pecurariu and published by Springer. This book was released on 2017-02-27 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a comprehensive approach to the wide range of movement disorders, an important specialty in the field of neurology, guiding readers from the phenomenology to diagnosis and management. Reflecting the latest developments in the field, it offers a unique summary of this dynamic area by pursuing a uniform approach to movement disorders curricula. Divided into three parts, Movement Disorders Curricula provides an authoritative overview of this growing branch of neurology. The first part presents the basic elements of movement disorders, including descriptions of the anatomy and physiology of the basal ganglia. It also features sections on clinical trials for movement disorders, practical skills, and rating scales. The second and third part examine in detail hypokinetic and hyperkinetic movement disorders, respectively. Equipping readers with the practical and research skills needed in the movement disorders field, the book offers a valuable tool to help them prepare for board examinations on general neurology, as well as for fellowships in movement disorders.

Download or read book Guide to Assessment Scales in Parkinson s Disease written by Pablo Martinez-Martin and published by Springer. This book was released on 2014-10-16 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Guide assesses the key clinimetric attributes in the assessment of Parkinson's Disease (PD), with the intention to offer rapid and pragmatic information on the most relevant scales used in PD. Parkinson’s disease affects approximately 4 million people globally and is most commonly seen in people over the age of 50. The disease is a progressive disorder of the nervous system, and presents a number of movement and cognitive symptoms, thereby greatly affecting a patients quality of life. The use of scales for assessment in neurological disorders such as PD arises from the need to quantify disorders and states (such constructs as disability, symptoms, quality of life). Assessment scales are often categorised into two categories: generic (i.e. those scales usable in any health condition), and specific (i.e. scales developed for exclusive use in PD). They can have a variety of components: single-item and multi-item or composite scale; unidimensional and multidimensional; and as disease-centered and patient-centered measures. The creation and validation of scales is complex, with scales undergoing numerous studies to assess criteria such as acceptability, reliability, and responsiveness. In the process of validation of a scale the following attributes should be tested to ascertain whether a scale is an effective instrument of measurement.

Download or read book Movement Disorders written by Richard A. Walsh and published by Oxford University Press. This book was released on 2017 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a practical guide to the diagnosis, management, and treatment of the principle movement disorders.