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Book New Techniques for Positron Emission Tomography in the Study of Human Neurological Disorders

Download or read book New Techniques for Positron Emission Tomography in the Study of Human Neurological Disorders written by and published by . This book was released on 1993 with total page 11 pages. Available in PDF, EPUB and Kindle. Book excerpt: This progress report describes accomplishments of four programs. The four programs are entitled (1) Faster, simpler processing of positron-computing precursors: New physicochemical approaches, (2) Novel solid phase reagents and methods to improve radiosynthesis and isotope production, (3) Quantitative evaluation of the extraction of information from PET images, and (4) Optimization of tracer kinetic methods for radioligand studies in PET.

Book New Techniques for Positron Emission Tomography in the Study of Human Neurological Disorders  Progress Report  June 1990  June 1993

Download or read book New Techniques for Positron Emission Tomography in the Study of Human Neurological Disorders Progress Report June 1990 June 1993 written by and published by . This book was released on 1993 with total page 11 pages. Available in PDF, EPUB and Kindle. Book excerpt: This progress report describes accomplishments of four programs. The four programs are entitled (1) Faster, simpler processing of positron-computing precursors: New physicochemical approaches, (2) Novel solid phase reagents and methods to improve radiosynthesis and isotope production, (3) Quantitative evaluation of the extraction of information from PET images, and (4) Optimization of tracer kinetic methods for radioligand studies in PET.

Book New Techniques for Positron Emission Tomography in the Study of Human Neurological Disorders

Download or read book New Techniques for Positron Emission Tomography in the Study of Human Neurological Disorders written by and published by . This book was released on 1992 with total page 5 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past six months, we have continued work on the fronts of kinetic modeling of radioligands for studying neurotransmitter/receptor systems, iterative reconstruction techniques, and methodology for PET cerebral blood flow activation studies. Initial human PET studies have been performed and analyzed with many different kinetic model formulations to determine the quantitative potential of the neuronwsmitter/receptor ligand, [11C]N-methyl piperidyl benzilate (NMPB), a muscarinic cholinergic antagonist. In addition, initial human studies using [11C]tetrabenazine (TBZ), a marker for monoantine nerve terminal density. Results of the NWB studies have indicated that this new agent yields better estimates of receptor density than previous muscarinic ligands developed at our facility, [11C]-TRB and [11C]scopolamine. TRB and scopolamine have previously been shown to be only partially successful ligands due to sub-optimal values of the individual rate constants, causing varying degrees of flow limitation. This is found to be much less of a problem for NMPB due to the 2.0--2.5 fold increase in ligand transport observed in the human studies ((approximately)60% first pass extraction). A 2-parameter 2-compartment simplification had previously been implemented for the benzodiazepine ligand, [C-11]FMZ, and a similar model appears to be suitable for TBZ based on the preliminary human data.

Book Positron Emission Tomography

    Book Details:
  • Author : Balázs Gulyás
  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • ISBN : 9401149968
  • Pages : 471 pages

Download or read book Positron Emission Tomography written by Balázs Gulyás and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: A critical summary of the state of the art of PET technology and related disciplines (camera physics, radiochemistry, radiopharmacology, computerised brain atlases and databases, etc.), plus a survey of the most recent developments in the clinical and neuroscience applications of PET. The chapters systematically guide the reader from the basics of the technique - including new camera designs, new drugs, and new statistical and image processing approaches - through its most important clinical applications - in neurology, psychiatry and oncology - to the most sophisticated neuroscience applications, including research into human sensory and motor systems, the functional organisation of imagery, volition, attention and consciousness in the human brain.

Book Quantitative Functional Brain Imaging with Positron Emission Tomography

Download or read book Quantitative Functional Brain Imaging with Positron Emission Tomography written by Richard E. Carson and published by Elsevier. This book was released on 1998-09-08 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest scientific developments in the field of positron emission tomography (PET) dealing with data acquisition, image processing, applications, statistical analysis, tracer development, parameter estimation, and kinetic modeling. It covers improved methodology and the application of existing techniques to new areas. The text also describes new approaches in scanner design and image processing, and the latest techniques for modeling and statistical analyses. This volume will be a useful reference for the active brain PET scientist, as well as a valuable introduction for students and researchers who wish to take advantage of the capabilities of PET to study the normal and diseased brain. Authored by international authorities in PET Provides the latest up-to-date techniques and applications Covers all fundamental disciplines of PET in one volume A comprehensive resource for students, clinicians, and new PET researchers

Book Brain Imaging in Behavioral Neuroscience

Download or read book Brain Imaging in Behavioral Neuroscience written by Cameron S. Carter and published by Springer Science & Business Media. This book was released on 2011-11-04 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume highlights the remarkable new developments in brain imaging, including those that apply magnetic resonance imaging (MRI) and Positron Emission Tomography (PET), that allow us to non invasively study the living human brain in health and in disease. These technological advances have allowed us to obtain new and powerful insights into the structure and function of the healthy brain as it develops across the life cycle, as well as the molecular make up of brain systems and circuits as they develop and change with age. New brain imaging technologies have also given us new insights into the causes of many common brain disorders, including ADHD, schizophrenia, depression and Alzheimer’s disease, which collectively affect a large segment of the population. These new insights have major implications for understanding and treating these brain disorders, and are providing clinicians with the first ever set of biomarkers that can be used to guide diagnosis and monitor treatment effects. The advances in brain imaging over the last 20 years, summarized in this volume, represent a major advance in modern biomedical sciences.

Book Positron Emission Tomography

Download or read book Positron Emission Tomography written by Sandro Misciagna and published by BoD – Books on Demand. This book was released on 2013-12-18 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Positron Emission Tomography is a nuclear medicine technique first used to study the brain. Several decades ago, PET scanners design and performance have improved considerably: number of detectors has increased from 20 to 20,0000, axial field of view from 2 to 20 cm, spatial resolution has improved from 25 to 5 mm, sensitivity has increased of about 1000 fold. At the same time, clinical applications have grown dramatically. In the first section of this book the authors review some of developments in PET instrumentation, with emphasis on data acquisition, processing and image formation. In the second section authors expose examples of applications in human research. In the last section authors describe applications in assessment and prediction of oncological treatment response.

Book Imaging of the Human Brain in Health and Disease

Download or read book Imaging of the Human Brain in Health and Disease written by Philip Seeman and published by Elsevier. This book was released on 2013-11-15 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain imaging technology remains at the forefront of advances in both our understanding of the brain and our ability to diagnose and treat brain disease and disorders. Imaging of the Human Brain in Health and Disease examines the localization of neurotransmitter receptors in the nervous system of normal, healthy humans and compares that with humans who are suffering from various neurologic diseases. Opening chapters introduce the basic science of imaging neurotransmitters, including sigma, acetylcholine, opioid, and dopamine receptors. Imaging the healthy and diseased brain includes brain imaging of anger, pain, autism, the release of dopamine, the impact of cannabinoids, and Alzheimer's disease. This book is a valuable companion to a wide range of scholars, students, and researchers in neuroscience, clinical neurology, and psychiatry, and provides a detailed introduction to the application of advanced imaging to the treatment of brain disorders and disease. A focused introduction to imaging healthy and diseased brains Focuses on the primary neurotransmitter release Includes sigma, acetylcholine, opioid, and dopamine receptors Presents the imaging of healthy and diseased brains via anger, pain, autism, and Alzheimer's disease

Book Physiological Imaging of the Brain with PET

Download or read book Physiological Imaging of the Brain with PET written by Albert Gjedde and published by Academic Press. This book was released on 2001 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physiological Imaging of the Brain with PET provides the latest techniques and applications for PET as a tool to study the physiology of the brain, and is sponsored by the International Society of Cerebral Blood Flow and Metabolism. It covers all of the fundamental disciplines of PET in one volume. Written by international experts in brain imaging, it is a useful reference for the active brain PET scientist, and a valuable introduction to students, clinicians, and researchers who wish to take advantage of the capabilities of this technique to study the normal and diseased brain. Key Features * Provides the latest techniques and applications of positron emission tomography (PET) * Covers all fundamental disciplines of PET in one volume * Serves as a comprehensive resource for students, clinicians and new researchers

Book PET and SPECT in Neurology

    Book Details:
  • Author : Rudi A. J. O. Dierckx
  • Publisher : Springer Nature
  • Release : 2020-10-20
  • ISBN : 3030531686
  • Pages : 1270 pages

Download or read book PET and SPECT in Neurology written by Rudi A. J. O. Dierckx and published by Springer Nature. This book was released on 2020-10-20 with total page 1270 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the use of PET and SPECT in not only classic neurodegenerative disorders but also cerebrovascular disorders, brain tumors, epilepsy, head trauma, coma, sleeping disorders, and inflammatory and infectious diseases of the CNS. The new edition has been revised and updated to reflect recent advances and includes additional chapters, for example on the use of artificial intelligence and machine learning in imaging data analysis, the study of brain connectivity using PET and SPECT images, and the role of PET imaging in modulation of brain functioning by deep brain stimulation. The authors are renowned experts whose dedication to the investigation of neurological disorders through nuclear medicine technology has achieved international recognition. Most chapters are written jointly by a clinical neurologist and a nuclear medicine specialist to ensure a multidisciplinary approach. This state of the art compendium will be invaluable for neurologists and radiologists/nuclear medicine specialists and will also be informative for interested general practitioners and geriatricians. Companion volumes on PET and SPECT in psychiatry and in neurobiological systems complete a trilogy.

Book NeuroPET

    Book Details:
  • Author : K. Herholz
  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • ISBN : 3642187668
  • Pages : 324 pages

Download or read book NeuroPET written by K. Herholz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: - Authors are all experts in the field; Herscovitch is head of PET Imaging at NIH. - PET is becoming dominant technology for diagnosis in Neurology; books have not caught up. NeuroPET is ahead of the curve.

Book Positron Emission Tomography

Download or read book Positron Emission Tomography written by and published by . This book was released on 1984 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Positron Emission Tomography in Dementia

Download or read book Positron Emission Tomography in Dementia written by Ranjan Duara and published by . This book was released on 1990 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is an up-to-date work that offers a full review of the relatively exclusive diagnostic tool--positron emission tomography--for studying dementing diseases. It describes, in easy-to-understand language, exactly how PET works, how to use it and analyze data, and what interpretations and conclusions can be drawn from this information. Includes comprehensive discussions on the application of PET for studying Alzheimer's Disease, Huntington's Disease, neuroreceptor changes in dementia, multi-infarct dementia and affinity and neurotransmitter concentrations.

Book Exploring Brain Functional Anatomy with Positron Tomography

Download or read book Exploring Brain Functional Anatomy with Positron Tomography written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Details the application of positron emission tomography (PET) to the mapping of human cerebral cortical function. Coverage includes all aspects of PET technology. Includes chapters on somatosensory, motor and visual systems, and higher-order processes such as attention, memory, learning, intention and language. The clinical usefulness of PET is discussed in relation to psychiatric illness and to functional recovery after brain injury.

Book Positron Emission Tomography of the Brain

Download or read book Positron Emission Tomography of the Brain written by W.-D. Heiss and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Symposium on Positron Emission Tomography of the Brain was held at Schloss Auel in Lohmar, near Cologne, FRG, on May 3rd to 8th, 1982. This isolated place was chosen to bring together and keep together people active in research employing PET. The partic ipants were asked to report their ongoing work, to discuss upcoming problems, and to indicate future developments. In contrast to the large international meetings which suffer from lack of time for discussion and are affected by the distractions of major cities, our symposium provided ample opportunity for discussion during the scientific sessions and guaranteed a free exchange of ideas during the leisure time spent to gether. It also gave us the chance to celebrate the founding of a new Max Planck Institute for Neurological Research, whose two depart ments are headed by Dr. K. -A. Hossmann and myself, and to mark the start of positron emission tomography in our laboratory. The book contains the invited papers presented at the meeting and the formal minipapers given at the final general discussion, moderated su perbly by Dr. L. Sokoloff. In order to accelerate publication, the discus sions of the individual papers and the final discussion have been omit ted. However, every participant will remember the atmosphere and the highlights of the discussions, which gave a special character to the whole event.

Book Positron Emission Tomography and Autoradiography

Download or read book Positron Emission Tomography and Autoradiography written by Michael E. Phelps and published by Lippincott Williams & Wilkins. This book was released on 1986 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book PET and SPECT in Psychiatry

Download or read book PET and SPECT in Psychiatry written by Rudi A.J.O. Dierckx and published by Springer Nature. This book was released on 2020-12-14 with total page 1075 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the use of PET and SPECT in the classic psychiatric disorders such as depression, bipolar disorder, anxiety disorders, and schizophrenia. In addition, it discusses the application of these functional neuroimaging techniques in a variety of other conditions, including sleep disorders, eating disorders, autism, and chronic fatigue syndrome. The new edition has been extensively revised and updated to reflect the latest advances and results in nuclear imaging within the field. Most chapters are written jointly by a clinical psychiatrist and a nuclear medicine expert to ensure a multidisciplinary approach. This state of the art compendium will be of value for all who have an interest in the field of neuroscience, from psychiatrists and radiologists/nuclear medicine specialists to interested general practitioners and cognitive psychologists. Companion volumes on the use of PET and SPECT in neurology and for the imaging of neurobiological systems complete a trilogy.