Download or read book New Strategies in Chemical Synthesis and Catalysis written by Bruno Pignataro and published by John Wiley & Sons. This book was released on 2012-05-21 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents one of the two edited by inviting a selection of young researchers participating to the European Young Chemist Award 2010. The other volume concerns the area of Nanotechnology/Material Science and is titled: Molecules at Work. This book contains the contributions of selected young chemists from the field of synthetic chemistry. The contributions are grouped under the three following umbrella topics: Synthetic Methods Catalysis Combinatorial and Chemical Biology This volume is an indispensable read for all organic and inorganic chemists, biochemists, chemists working with/on organometallics, and Ph.D. students in chemistry interested in seeing what tomorrow's chemistry will look like.

Download or read book Beyond the Molecular Frontier written by National Research Council and published by National Academies Press. This book was released on 2003-03-19 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemistry and chemical engineering have changed significantly in the last decade. They have broadened their scopeâ€"into biology, nanotechnology, materials science, computation, and advanced methods of process systems engineering and controlâ€"so much that the programs in most chemistry and chemical engineering departments now barely resemble the classical notion of chemistry. Beyond the Molecular Frontier brings together research, discovery, and invention across the entire spectrum of the chemical sciencesâ€"from fundamental, molecular-level chemistry to large-scale chemical processing technology. This reflects the way the field has evolved, the synergy at universities between research and education in chemistry and chemical engineering, and the way chemists and chemical engineers work together in industry. The astonishing developments in science and engineering during the 20th century have made it possible to dream of new goals that might previously have been considered unthinkable. This book identifies the key opportunities and challenges for the chemical sciences, from basic research to societal needs and from terrorism defense to environmental protection, and it looks at the ways in which chemists and chemical engineers can work together to contribute to an improved future.

Download or read book Asymmetric Organocatalysis written by Lukasz Albrecht and published by John Wiley & Sons. This book was released on 2022-11-10 with total page 1092 pages. Available in PDF, EPUB and Kindle. Book excerpt: Asymmetric Organocatalysis Comprehensive resource on the latest and most important developments in the highly vivid field of asymmetric organocatalysis The book provides a comprehensive overview of the most important advancements in the field of asymmetric organocatalysis that have occurred within the last decade. It presents valuable examples of newly developed synthetic methodologies based on various organocatalytic activation modes. Special emphasis is given to strategies where organocatalysis is expanding its potential by pushing the boundaries and founding new synergistic interactions with other fields of synthetic chemistry, such as metal catalysis, photocatalysis, and biocatalysis. The application of different concepts (such as vinylogy, dearomatization, or cascade reactivity), resulting in the development of new functionalization strategies, is also discussed. Sample topics covered within the book include: New developments in enantioselective Brønsted acid catalysis with strong hydrogen-bond donors Asymmetric phase-transfer catalysis, from classical applications to new concepts Halogen-bonding organocatalysis Asymmetric electrochemical organocatalysis and synergistic organo-organocatalysis Immobilized organocatalysts for enantioselective continuous flow processes Mechanochemistry and high-pressure techniques in asymmetric organocatalysis Useful tools in elucidation of organocatalytic reaction mechanisms With an overall focus on new reactions and catalysts, this two-volume work is an indispensable source for everyone working in the field of asymmetric organocatalysis.

Download or read book New Frontiers in Asymmetric Catalysis written by Koichi Mikami and published by John Wiley & Sons. This book was released on 2007-02-16 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: A compilation of recent advances and applications in asymmetric catalysis The field of asymmetric catalysis has grown rapidly and plays a key role in drug discovery and pharmaceuticals. New Frontiers in Asymmetric Catalysis gives readers a fundamental understanding of the concepts and applications of asymmetric catalysis reactions and discusses the latest developments and findings. With contributions from preeminent scientists in their respective fields, it covers: * "Rational" ligand design, which is critically dependent on the reaction type (reduction, oxidation, and C-C bond formation) * Recent findings on activation of C-H bonds, C-C bonds, and small molecules (C=O, HCN, RN=C, and CO2) and the latest developments on C-C bond reorganization, such as metathesis * Advances in "chirally economical" non-linear phenomena, racemic catalysis, and autocatalysis * Some of the recent discoveries that have led to a renaissance in the field of organocatalysis, including the development of chiral Brönstead acids and Lewis acidic metals bearing the conjugate base of the Brönstead acids as the ligands and the chiral bi-functional acid/base catalysts The book ends with a thought-provoking perspective on the future of asymmetric catalysis that addresses both the challenges and the unlimited potential in this burgeoning field. This is an authoritative, up-to-date reference for organic chemists in academia, government, and industries, including pharmaceuticals, biotech, fine chemicals, polymers, and agriculture. It is also an excellent textbook for graduate students studying advanced organic chemistry or chemical synthesis.

Download or read book Asymmetric Synthesis with Chemical and Biological Methods written by Dieter Enders and published by John Wiley & Sons. This book was released on 2007-06-27 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by two of the leading researchers in the field, this book provides a deep, interdisciplinary insight into stoichiometric and catalytic reactions in this continuously expanding area. A plethora of top German scientists with an international reputation covers various aspects, from classical organic chemistry to process development, and from the theoretical background to biological methods using enzymes. Throughout the focus is on the development of new synthetic methods in asymmetric synthesis, the synthesis of natural and bioactive compounds and the latest developments in both chemical and biological methods of catalysis, as well as the investigation of special technical and biotechnical aspects.

Download or read book Sustainable Organic Synthesis written by Dr Stefano Protti and published by Royal Society of Chemistry. This book was released on 2021-10-29 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen huge growth in the area of sustainable chemistry. In order to meet the chemical needs of the global population whilst minimising impacts on health and the environment it is essential to keep reconsidering and improving synthetic processes. Sustainable Organic Synthesis is a comprehensive collection of contributions, provided by specialists in Green Chemistry, covering topics ranging from catalytic approaches to benign and alternative reaction media, and innovative and more efficient technologies.

Download or read book Design and Strategy in Organic Synthesis written by Stephen Hanessian and published by Wiley-VCH. This book was released on 2013-09-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This long-awaited graduate level book, written by one of the world's leading organic chemists in collaboration with two of his former and present coworkers, adopts a refreshingly unique approach to synthesis planning and execution. Following an introductory look at the concept of synthesis, the authors discuss the Why, What, and How of organic synthesis as they apply to natural products. Although emphasis is on the Chiron Approach utilizing amino-acids, carbohydrates, hydroxy acids, terpenes, lactones and other naturally occurring small molecules as starting materials, catalytic asymmetric methods are also included as a corollary whenever relevant. A must-have source of first class information for everyone working in organic synthesis, be it in academia or industry. With a foreword by Larry E. Overman and David W. C. MacMillan

Download or read book New Avenues to Efficient Chemical Synthesis written by P.H. Seeberger and published by Springer Science & Business Media. This book was released on 2007-06-02 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: In modern drug discovery and development, chemical synthesis is one of the key technologies. For the rapid preparation of new test compounds and drug development candidates, several innovative technologies with great potential have emerged. This book offers a compact overview of the current status of these technologies and includes many real-life examples from industry and academic institutions.

Download or read book Classics in Total Synthesis written by K. C. Nicolaou and published by John Wiley & Sons. This book was released on 1996-04-11 with total page 826 pages. Available in PDF, EPUB and Kindle. Book excerpt: K.C. Nicolaou - Winner of the Nemitsas Prize 2014 in Chemistry This book is a must for every synthetic chemist. With didactic skill and clarity, K. C. Nicolaou and E. Sorensen present the most remarkable and ingenious total syntheses from outstanding synthetic organic chemists. To make the complex strategies more accessible, especially to the novice, each total synthesis is analyzed retrosynthetically. The authors then carefully explain each synthetic step and give hints on alternative methods and potential pitfalls. Numerous references to useful reviews and the original literature make this book an indispensable source of further information. Special emphasis is placed on the skillful use of graphics and schemes: Retrosynthetic analyses, reaction sequences, and stereochemically crucial steps are presented in boxed sections within the text. For easy reference, key intermediates are also shown in the margins. Graduate students and researchers alike will find this book a gold mine of useful information essential for their daily work. Every synthetic organic chemist will want to have a copy on his or her desk.

Download or read book Organic Synthesis written by Paul Wyatt and published by John Wiley & Sons. This book was released on 2013-05-20 with total page 55 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Synthesis: Strategy and Control is the long-awaited sequel to Stuart Warren's bestseller Organic Synthesis: The Disconnection Approach, which looked at the planning behind the synthesis of compounds. This unique book now provides a comprehensive, practical account of the key concepts involved in synthesising compounds and focuses on putting the planning into practice. The two themes of the book are strategy and control: solving problems either by finding an alternative strategy or by controlling any established strategy to make it work. The book is divided into five sections that deal with selectivity, carbon-carbon single bonds, carbon-carbon double bonds, stereochemistry and functional group strategy. * A comprehensive, practical account of the key concepts involved in synthesising compounds * Takes a mechanistic approach, which explains reactions and gives guidelines on how reactions might behave in different situations * Focuses on reactions that really work rather than those with limited application * Contains extensive, up-to-date references in each chapter Students and professional chemists familiar with Organic Synthesis: The Disconnection Approach will enjoy the leap into a book designed for chemists at the coalface of organic synthesis.

Download or read book More Dead Ends and Detours written by Miguel A. Sierra and published by John Wiley & Sons. This book was released on 2013-07-11 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Success comes in many forms and in synthesis it can be a failure that results in their ultimate successful solutions. This long-awaited sequel to "Dead Ends and Detours" retains the proven concept while featuring over 20 new case studies of failed strategies and their (successful) solutions in natural product total synthesis. Additionally, computational models are used to discuss the problem in much more detail and to provide readers with additional information not found in the primary literature. The topics range from classic synthetic reactions (e.g. Diels Alder reaction), metal-mediated coupling reactions, metathesis, and asymmetric catalysis to the importance of protecting and activating groups. This book will benefit not only graduate students in organic chemistry but also advanced researchers as they gain knowledge derived from the step-by-step analysis of mistakes made in the past and, thus be able to improve their own chemical reaction planning. With its coverage of the most commonly applied reaction types, the book perfectly complements its predecessor, which focuses on general aspects, such as reactivity and selectivity.

Download or read book Enabling Tools and Techniques for Organic Synthesis written by Stephen G. Newman and published by John Wiley & Sons. This book was released on 2023-09-26 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides the practical knowledge of how new technologies impact organic synthesis, enabling the reader to understand literature, evaluate different techniques, and solve synthetic challenges In recent years, new technologies have impacted organic chemistry to the point that they are no longer the sole domain of dedicated specialists. Computational chemistry, for example, can now be used by organic chemists to help predict outcomes, understand selectivity, and decipher mechanisms. To be prepared to solve various synthetic problems, it is increasingly important for chemists to familiarize themselves with a range of current and emerging tools and techniques. Enabling Tools and Techniques for Organic Synthesis A Practical Guide to Experimentation, Automation, and Computation provides a broad overview of contemporary research and new technologies applied to organic synthesis. Detailed chapters, written by a team of experts from academia and industry, describe different state-of-the-art techniques such as computer-assisted retrosynthesis, spectroscopy prediction with computational chemistry, high throughput experimentation for reaction screening, and robotic and automated data collection methods. Emphasizing real-world practicality, the book includes chapters on programming for synthetic chemists, Machine Learning (ML) in chemical synthesis, concepts and applications of computational chemistry, and more. Highlights the most recent methods in organic synthesis and describes how to employ these techniques in a reader’s own research Familiarize readers with the application of computational chemistry and automation technology in organic synthesis Introduces synthetic chemists to electrochemistry, photochemistry, and flow chemistry Helps readers comprehend the literature, assess the strengths and limitations of each technique, and apply those tools to solve synthetic challenges Provides case studies and guided examples with graphical illustrations in each chapter Enabling Tools and Techniques for Organic Synthesis: A Practical Guide to Experimentation, Automation, and Computation is an invaluable reference for scientists needing an up-to-date introduction to new tools, graduate students wanting to expand their organic chemistry skills, and instructors teaching courses in advanced techniques for organic synthesis.

Download or read book Innovative Catalysis in Organic Synthesis written by Pher G. Andersson and published by John Wiley & Sons. This book was released on 2012-04-16 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: C-H, C-O, C-C, and C-Heteroatom bond forming processes by using metal-ligand approaches for the synthesis of organic compounds of biological, pharmacological and organic nanotechnological utility are the key areas addressed in this book. Authored by a European team of leaders in the field, it brings together innovative approaches for a variety of catalysis reactions and processes frequently applied in organic synthesis into a handy reference work. It covers all major types of catalysis, including homogeneous, heterogeneous, and organocatalysis, as well as mechanistic and computational studies. Special attention is paid to the improvements in efficiency and sustainability of important catalytic processes, such as selective oxidations, hydrogenation, and cross-coupling reactions, and to their utilization in industry. The result is a valuable resource for advanced researchers in both academia and industry, as well as graduate students in organic chemistry aiming for chemo-, regio- or stereoselective synthesis of organic compounds by using novel catalytic systems.

Download or read book Classics in Total Synthesis II written by K. C. Nicolaou and published by Wiley-VCH. This book was released on 2003-10-17 with total page 639 pages. Available in PDF, EPUB and Kindle. Book excerpt: Classics in Total Synthesis II is the long awaited sequel to Classics in Total Synthesis, a book that has made its mark as a superb tool for educating students and practitioners alike in the art of organic synthesis since its introduction in 1996. In this highly welcomed second volume, K.C. Nicolaou and Scott A. Snyder discuss in detail the most impressive accomplishments in natural product total synthesis during the 1990s and the first years of the 21st century. While all of the features that made the first volume of Classics so popular and unique as a teaching tool have been maintained, in this new treatise the authors seek to present the latest techniques and advance in organic synthesis as they beautifully describe the works of some of the most renowned synthetic organic chemists of our time. Key features include: Systematically develops domino reactions, cascade sequences, biomimetic strategies, and asymmetric catalysis through the chosen synthesis Discusses cutting edge synthetic technologies in terms of mechanism and scope Presents new reactions, such as olefin metathesis, in mini-review style Includes abundant references for further reading CD with useful teaching material for lecturers is included with hardback version (ISBN 3-527-30685-4) Graduate students, educators, and researchers in the fields of synthetic and medicinal chemistry will wish to have a copy of this book in their collection as an indispensable companion that both augments and supplements the original Classics in Total Synthesis. From the reviews: "... a volume, (...) which any chemist with an interest in synthetic organic chemistry will wish to acquire." –JACS (on the previous volume) "...this superb book (...) will be an essential purchase for many organic chemists." –Nature (on the previous volume) "...Classics II is undoubtedly an excellent bargain that is highly recommended to everybody interested in advanced organic chemistry. One of my co-workers confessed that Classics I was the book on his bedside table while he prepared his thesis defense. Isn't that the highest distinction for a monograph? I have every reason to believe that Classics II will equally stand the selection process by students (and probably their supervisors too)." –Angewandte Chemie, 2004 "Well, there is a new pleasant read for the advanced student and even the experienced. It is the second volume to the established Classics in Total Synthesis and it continues the series extremely well." –ChemBioChem, 2004 "...the real innovation of this volume is the inclusion of alternative pathways to the same target molecule by other researchers. This enables the reader to appreciate that there are also other solutions to certain structural problems than those of the original synthesis. ... Let us hope that K. C. Nicolaou and his associates will present us with these future achievements in the same clear, informative and innovative format they have with the previous two volumes." –Applied Organometallic Chemistry

Download or read book Classics in Stereoselective Synthesis written by Erick M. Carreira and published by John Wiley & Sons. This book was released on 2009-02-09 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Die wichtigsten und nützlichsten Methoden der modernen stereoselektiven Synthese sind in diesem Band zusammengefasst. Viele anschauliche Beispiele für die Darstellung von Wirkstoffen und Naturstoffen regen zur gezielten Abwandlung und Integration in eigene Synthesewege an. Dabei geht es den Autoren weniger darum, das Gebiet in seiner Gesamtheit darzustellen; vielmehr versuchen sie, die wirklich grundlegenden Ansätze auszuwählen, die jeder organische Synthesechemiker kennen und anwenden sollte.

Download or read book Total Synthesis of Natural Products written by Jie Jack Li and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.

Download or read book Green Techniques for Organic Synthesis and Medicinal Chemistry written by Wei Zhang and published by John Wiley & Sons. This book was released on 2018-01-18 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: An updated overview of the rapidly developing field of green techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique’s features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal Chemistry includes 7 entirely new chapters on topics including green chemistry and innovation, green chemistry metrics, green chemistry and biological drugs, and the business case for green chemistry in the generic pharmaceutical industry. It is divided into 4 parts. The first part introduces readers to the concepts of green chemistry and green engineering, global environmental regulations, green analytical chemistry, green solvents, and green chemistry metrics. The other three sections cover green catalysis, green synthetic techniques, and green techniques and strategies in the pharmaceutical industry. Includes more than 30% new and updated material—plus seven brand new chapters Edited by highly regarded experts in the field (Berkeley Cue is one of the fathers of Green Chemistry in Pharma) with backgrounds in academia and industry Brings together a team of international authors from academia, industry, government agencies, and consultancies (including John Warner, one of the founders of the field of Green Chemistry) Green Techniques for Organic Synthesis and Medicinal Chemistry, Second Edition is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in organic chemistry and medicinal chemistry.