Download or read book New Paradigms in Cellular Physiology and Pathology written by Christopher Shelley and published by American Medical Publishers. This book was released on 2023-09-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cell is the basic structural and functional unit of life. Cell physiology refers to the biological study of the various processes that take place in the cell, which keep it alive. In living systems, free radicals such as reactive oxygen species (ROS) and reactive nitrogen species (RNS) play a crucial role in regulating a wide range of cell activities such as autophagy, metabolism, growth and development, solute transport, programmed cell death, and stress responses. Furthermore, ROS and RNS can damage tissues through oxidative stress and tissue dysfunction, and they can also act as molecular messengers for stress responses that are advantageous to the organism. Cellular pathology on the other hand, studies the diseases that occur in the cells, tissues and organs. The primary diagnostic tests that are utilized in cell pathology include cytopathology and histopathology. This book provides an insight into the new paradigms in the research on cellular physiology and pathology. It will serve as a valuable source of reference for graduate and post graduate students.
Download or read book Autophagy in Current Trends in Cellular Physiology and Pathology written by Nikolai Gorbunov and published by BoD – Books on Demand. This book was released on 2016-11-10 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy in Current Trends in Cellular Physiology and Pathology is addressed to one of the fundamental molecular mechanisms - autophagy- evolutionarily adopted by cells for processing of unnecessary or malfunctioned constituents and shaping intracellular structures, adjusting them to environmental conditions, aging, disease, neoplasia, and damages over their life period. Particular attention is paid to autophagy-mediated barrier processes of selective sequestration and recycling of impaired organelles and degradation of invading microorganisms, that is, the processes sustaining intrinsic resistance to stress, tissue degeneration, toxic exposures, and infections. The presented topics encompass personal experience and visions of the chapter contributors and the editors; the book chapters include a broad analysis of literature on biology of autophagy.
Download or read book Cell Surface GRP78 a New Paradigm in Signal Transduction Biology written by Salvatore V. Pizzo and published by Academic Press. This book was released on 2018-03-20 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Surface GRP78, a New Paradigm in Signal Transduction Biology presents a new paradigm that has emerged in the past decade with the discovery that various intracellular proteins may acquire new functions as cell surface receptors. Two very prominent examples are ATP synthase and GRP78. While the role of cell surface ATP synthase has been reviewed in various books, this book directs its attention to the story of cell surface GRP78. - Edited by the researcher who identified cell surface expression of the molecular chaperone GRP78 as a major factor in prostate cancer and other malignancies - Presents an in-depth treatment of the biological underpinnings of GRP78 and its connection to disease - Provides four-color illustrations that facilitate the narrative
Download or read book Journey to the Center of the Brain Cell Physiology and Intercellular Communication In White Matter written by Maria Kukley and published by Frontiers Media SA. This book was released on 2022-04-05 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Current Topics in Bone Biology written by Hong-wen Deng and published by World Scientific. This book was released on 2005 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers a wide spectrum of areas related to basic bone research. While bone remodeling, bone development, and osteoclast biology constitute the main contents, topics important to the understanding of bone metabolism and treatment of bone-related diseases are also intensively reviewed. Three chapters are dedicated to the classic topic of bone mechanics, which include a brief overview of the mechanostat hypothesis, a more detailed review on mechanotransduction and bone adaptation, and a chapter illustrating the basic principles of bone mechanical testing. New emerging fields such as skeletal stem cells, bone tissue engineering, phytoestrogens applications, and bone genetics study using mouse models, are also covered in detail. The book closes with a special chapter dedicated to state-of-the-art advances in bone biology research.
Download or read book Oxidative Stress in Exercise Physiology written by James N. Cobley and published by . This book was released on 2022 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book aims to unravel key physiological responses and adaptations to exercise paradigms regulated at the cell, tissue, and whole-body level in model systems and in humans both with respect to health and disease. By unravelling and contextualising how fundamental chemistry impacts biology at the physiological level, this book offers enduring appeal for scientists working in disparate disciplines. The present work recruited world-leading contributors, known as experts in their chosen field, to provide a comprehensive resource for new and established investigators working in the field, as well as, serving as a primer for those interested in the field"--
Download or read book Stretch Intensity and the Inflammatory Response A Paradigm Shift written by Nikos C. Apostolopoulos and published by Springer. This book was released on 2018-12-27 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this manuscript, practitioners and students who are concerned with sports and rehabilitation medicine, kinesiology, as well as coaches and athletes, are introduced to numerous concepts, including mechanotransduction, inflammation, pro- and anti-inflammatory cytokines, calpains, the extracellular matrix, neutrophils and macrophages, and their relevance to stretching, particularly stretching intensity. Although the quantitative parameters of training, duration, and frequency are important, it is the qualitative criterion of intensity (“how much”) that the author suggests is ultimately of greater concern. Intensity, the rate and magnitude of force, may be responsible for the proper recovery, regeneration, and adaptation of the musculoskeletal tissues from training, competition, or rehabilitation from injuries. Research suggests that too much force results in the stimulation of an inflammatory response, one associated with a biochemical feedback emerging from a mechanical stimulus. The intent of this manuscript is twofold: to initiate the discussion of the importance of stretching intensity with regard to proper recovery, regeneration, and adaptation, and to suggest that researchers need to explore its potential role in addressing numerous inflammatory (RA) and non-inflammatory (OA, recurrent tendinitis etc.) musculoskeletal conditions as well.
Download or read book Selected Chapters from the Renin Angiotensin System written by Aleksandar Kibel and published by BoD – Books on Demand. This book was released on 2020-08-19 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Selected Chapters from the Renin-Angiotensin System aims to provide a comprehensive overview of the most important physiological and pathophysiological roles of the renin-angiotensin system (RAS). The complex and convoluted RAS has been investigated for many years and, through rigorous scientific research, many important and previously unknown components and functions of the RAS have come to light. These discoveries have been crucial in the understanding of this system and provide a basis for effective modulation of the system as part of therapeutic strategies for a number of widespread disorders. New studies are continuing to elucidate the RAS and the mechanisms associated with its functions. This book discusses relevant scientific knowledge about the RAS and intends to introduce the reader to cutting-edge research with an accentuation on the mechanisms at the functional/physiological and molecular/cellular levels.
Download or read book Pathophysiology E Book written by Jacquelyn L. Banasik and published by Elsevier Health Sciences. This book was released on 2021-05-29 with total page 1218 pages. Available in PDF, EPUB and Kindle. Book excerpt: - NEW! Next Generation NCLEX® (NGN)-style case studies on the companion Evolve website help strengthen your clinical judgment skills in preparation for the new item types on the exam. - NEW! COVID-19 coverage includes the most current scientific findings, prevalence, mechanism of disease, transmission, and treatment implications.
Download or read book Physiology and Pathology of Neuroglia written by Reyes-Haro and published by Frontiers Media SA. This book was released on 2023-08-07 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Allostasis Homeostasis and the Costs of Physiological Adaptation written by Jay Schulkin and published by Cambridge University Press. This book was released on 2004-10-25 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of homeostasis, the maintenance of the internal physiological environment of an organism within tolerable limits, is well established in medicine and physiology. In contrast, allostasis is a relatively new idea of 'viability through change'. With allostatic regulation by cephalic involvement, the body adapts to potentially diverse and dangerous situations through the activation of neural, hormonal, or immunological mechanisms. Allostasis explains how regulatory events maintain organismic viability, or not, in diverse contexts with varying set points of bodily needs and competing motivations. This 2005 book introduces the concept of allostasis and sets it alongside traditional views of homeostasis. It addresses basic regulatory systems and examines the behavior of bodily regulation under duress. The basic concepts of physiological homeostasis are integrated with disorders like depression, stress, anxiety and addiction. It will therefore appeal to graduate students, medical students and researchers working in physiology, epidemiology, endocrinology, neuroendocrinology, neuroscience, and psychology.
Download or read book New Paradigms in Neuroscience and Related Targets for Drug Discovery written by Salvatore Salomone and published by Frontiers Media SA. This book was released on 2020-07-02 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Aldosterone Mineralocorticoid Receptor written by Brian Harvey and published by BoD – Books on Demand. This book was released on 2019-09-25 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an open access dissemination of the EU COST Action ADMIRE in Aldosterone/Mineralocorticoid Receptor (MR) physiology and pathophysiology. Aldosterone is the major hormone regulating blood pressure. Alterations in blood levels of aldosterone and genetic mutations in the MR receptor are major causes of hypertension and comorbidities. Many of the drugs in clinical use, and in development for treating hypertension, target aldosterone and MR actions in the kidney and cardiovascular system. The ADMIRE book assembles review chapters from 16 European ADMIRE laboratories providing the latest insights into mechanisms of aldosterone synthesis/secretion, aldosterone/MR physiology and signaling, and the pathophysiological roles of aldosterone/MR activation.
Download or read book Handbook Positive Health in Primary Care written by Machteld Huber and published by Springer Nature. This book was released on 2021-11-10 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing numbers of general practitioners are discovering the benefits of working with Positive Health. It helps to talk with patients in a different way, with a focus on possibilities rather than on the impossibilities related to a particular health problem. This is good for the patient. And for the general practitioner. But how do we apply Positive Health? This handbook provides useful tools! The book is full of tips, tells the story of how the concept was first developed and gives practical examples. It explains the underlying scientific basis of Positive Health — with a clear emphasis on what is meaningful to patients. And, above all, this book invites you to start working with Positive Health on various levels — in your consulting room, your practice and in the local community. Because cooperation and combined effort are key. You will experience how Positive Health seamlessly fits the core values and challenges of all aspects of primary care. The handbook is intended for all primary care professionals as well as those who are still in training. It describes the Dutch health care system and the experiences related to inspiration, implementation and the anchoring of the Positive Health concept into this system. The publication is indispensable for anyone who wants to provide meaningful primary care using the Positive Health concept. ‘When I heard about Positive Health and the spider web, I felt that it gave us a much wanted tool to empower our patients and the community.’ Elínborg Bárðardóttir, general practitioner & programme director primary care training, Primary Healthcare in Iceland
Download or read book Natriuretic Peptides in Cardiovascular Pathophysiology written by Massimo Volpe and published by Frontiers Media SA. This book was released on 2022-06-03 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microscopy Immunohistochemistry and Antigen Retrieval Methods written by M.A. Hayat and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Histochemistry deals with the activities of chemical components in cells, and immunohistochemistry addresses the function of cell types in tissue or organs, such as those leading to acceptance or rejection of grafts or organs. This book is a methods volume focusing on antigen retrieval, particularly methods used in disease-related antigens. Because the book is a methods volume and a lab manual, it will have an audience of pathologists, biochemists, and lab technicians.
Download or read book The Paradigm Shift in Health written by Ronald S. Laura and published by . This book was released on 2009 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors of this book show that the failure of public health arises, not from a failure of contemporary medicine, but from a failure of the philosophical assumptions upon which it rests. They suggest an alternative approach to health care that derives from a ecological and holistic philosophy of nature.
