Download or read book New Horizons in Natural Compound Research written by Surya Nandan Meena and published by Elsevier. This book was released on 2023-04-18 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Horizons in Natural Compound Research provides the latest updates in natural compound research (plant, microbes, algae, fungi) and their novel applications in health, agriculture and environment. The book gives recent advances in the extraction of natural compounds, cutting-edge approaches for natural compound purifications, and emerging trends in natural compound screening and identification. In addition, it provides a detailed explanation of the databases and libraries of natural compounds, as well as their significance. Sections focus on research and multidisciplinary practical techniques of natural product research, encouraging young scientists to pursue unique research while also generating strong research ideas. From a future perspective, this book acts as a guide to identify potential areas and new research opportunities in the field of natural products and their service towards human beings, animals and the environment. Provides a one–stop solution for concepts, cutting-edge techniques, methods, and novel applications of natural products in health and the environment Focuses on current gaps in natural product research, as well as methodologies and techniques to assist researchers in resolving existing challenges and speeding up the pace of drug discovery from natural sources Highlights new avenues of natural product research Contains contributions from well-experienced researchers from academia, research institutes and top-notch young scientists from industry

Download or read book Artificial Intelligence and Machine Learning in Drug Design and Development written by Abhirup Khanna and published by John Wiley & Sons. This book was released on 2024-06-21 with total page 737 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book is a comprehensive guide that explores the use of artificial intelligence and machine learning in drug discovery and development covering a range of topics, including the use of molecular modeling, docking, identifying targets, selecting compounds, and optimizing drugs. The intersection of Artificial Intelligence (AI) and Machine Learning (ML) within the field of drug design and development represents a pivotal moment in the history of healthcare and pharmaceuticals. The remarkable synergy between cutting-edge technology and the life sciences has ushered in a new era of possibilities, offering unprecedented opportunities, formidable challenges, and a tantalizing glimpse into the future of medicine. AI can be applied to all the key areas of the pharmaceutical industry, such as drug discovery and development, drug repurposing, and improving productivity within a short period. Contemporary methods have shown promising results in facilitating the discovery of drugs to target different diseases. Moreover, AI helps in predicting the efficacy and safety of molecules and gives researchers a much broader chemical pallet for the selection of the best molecules for drug testing and delivery. In this context, drug repurposing is another important topic where AI can have a substantial impact. With the vast amount of clinical and pharmaceutical data available to date, AI algorithms find suitable drugs that can be repurposed for alternative use in medicine. This book is a comprehensive exploration of this dynamic and rapidly evolving field. In an era where precision and efficiency are paramount in drug discovery, AI and ML have emerged as transformative tools, reshaping the way we identify, design, and develop pharmaceuticals. This book is a testament to the profound impact these technologies have had and will continue to have on the pharmaceutical industry, healthcare, and ultimately, patient well-being. The editors of this volume have assembled a distinguished group of experts, researchers, and thought leaders from both the AI, ML, and pharmaceutical domains. Their collective knowledge and insights illuminate the multifaceted landscape of AI and ML in drug design and development, offering a roadmap for navigating its complexities and harnessing its potential. In each section, readers will find a rich tapestry of knowledge, case studies, and expert opinions, providing a 360-degree view of AI and ML’s role in drug design and development. Whether you are a researcher, scientist, industry professional, policymaker, or simply curious about the future of medicine, this book offers 19 state-of-the-art chapters providing valuable insights and a compass to navigate the exciting journey ahead. Audience The book is a valuable resource for a wide range of professionals in the pharmaceutical and allied industries including researchers, scientists, engineers, and laboratory workers in the field of drug discovery and development, who want to learn about the latest techniques in machine learning and AI, as well as information technology professionals who are interested in the application of machine learning and artificial intelligence in drug development.

Download or read book New Horizons in the Study of Language and Mind written by Noam Chomsky and published by Cambridge University Press. This book was released on 2000-04-13 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Outstanding and unique contribution to the philosophical study of language and mind by Noam Chomsky.

Download or read book Monthly Catalog of United States Government Publications written by United States. Superintendent of Documents and published by . This book was released on 1959 with total page 1714 pages. Available in PDF, EPUB and Kindle. Book excerpt: February issue includes Appendix entitled Directory of United States Government periodicals and subscription publications; September issue includes List of depository libraries; June and December issues include semiannual index.

Download or read book New Horizons written by Richard T. Coffey and published by The American Oil Chemists Society. This book was released on 1996 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Selected Topics in the Chemistry of Natural Products written by Raphael Ikan and published by World Scientific. This book was released on 2008 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: A New York Times Notable Book for 2011 A Globe and Mail Best Books of the Year 2011 Title A Kirkus Reviews Best Nonfiction of 2011 title Virtually all human societies were once organized tribally, yet over time most developed new political institutions which included a central state that could keep the peace and uniform laws that applied to all citizens. Some went on to create governments that were accountable to their constituents. We take these institutions for granted, but they are absent or are unable to perform in many of today’s developing countries—with often disastrous consequences for the rest of the world. Francis Fukuyama, author of the bestselling The End of History and the Last Man and one of our most important political thinkers, provides a sweeping account of how today’s basic political institutions developed. The first of a major two-volume work, The Origins of Political Order begins with politics among our primate ancestors and follows the story through the emergence of tribal societies, the growth of the first modern state in China, the beginning of the rule of law in India and the Middle East, and the development of political accountability in Europe up until the eve of the French Revolution. Drawing on a vast body of knowledge—history, evolutionary biology, archaeology, and economics—Fukuyama has produced a brilliant, provocative work that offers fresh insights on the origins of democratic societies and raises essential questions about the nature of politics and its discontents.

Download or read book Seeing New Horizons written by Dr. Barry Hulon Hyde and published by Page Publishing Inc. This book was released on 2020-12-29 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Well-Grounded Aviator June 1, 1998: While flying as a passenger, I survived a plane crash with traumatic head injuries and a loss of smell, taste, and sight. August 15, 1999: Went to the Rehabilitation for the Blind in Raleigh to learn all new life skills. June 6, 2000: Became the first and only blind Advanced Ground Instructor (AGI) in the world. June 12, 2000: Received first Guide Dog, Lincoln, from Southeastern Guide Dog Incorporated. October, 2000: Became first and only blind Instrument Ground Instructor (IGI) in the world. December, 2004, graduated from University of North Carolina at Charlotte (UNCC), with Lincoln the Navigator. May, 2007, graduated from Embry-Riddle Aeronautical University (ERAU), with Lincoln the Aviator, became the first and only blind graduate student in their 82 year history, and graduated with distinction. June 1, 2007: Nine year anniversary of the accident, began doctoral degree in business administration with a specialization in aeronautical safety, online at Northcentral University. January 20, 2009: Jet, my second Guide Dog came into my life from Guide Dog Foundation. March 1, 2010: Began work with the FAA as an Aviation Safety Analyst with the Commercial and General Aviation Branch, AFS-800, at Headquarters in Washington, DC. August 1, 2014: Married Robin at Graceland, in Elvis’s Chapel in the Woods. July 5, 2017: Dissertation completed and gave oral defense of: “The Relationship between Pilot Attitudes and the execution of Flight Safety Checklists”, to become Dr. Hyde. July 30, 2018, Bravo, third Guide dog received from Southeastern Guide Dog Incorporated. ERAU’s first president, Jack R. Hunt, had a famous saying, “For most people, the sky is the limit. But for those who love aviation, the sky is home.” For me, the sky is home, and I will always want to be a part of flying the friendly skies.

Download or read book Achievements of the National Plant Genome Initiative and New Horizons in Plant Biology written by National Research Council and published by National Academies Press. This book was released on 2008-03-20 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Life on Earth would be impossible without plants. Humans rely on plants for most clothing, furniture, food, as well as for many pharmaceuticals and other products. Plant genome sciences are essential to understanding how plants function and how to develop desirable plant characteristics. For example, plant genomic science can contribute to the development of plants that are drought-resistant, those that require less fertilizer, and those that are optimized for conversion to fuels such as ethanol and biodiesel. The National Plant Genome Initiative (NPGI) is a unique, cross-agency funding enterprise that has been funding and coordinating plant genome research successfully for nine years. Research breakthroughs from NPGI and the National Science Foundation (NSF) Arabidopsis 2010 Project, such as how the plant immune system controls pathogen defense, demonstrate that the plant genome science community is vibrant and capable of driving technological advancement. This book from the National Research Council concludes that these programs should continue so that applied programs on agriculture, bioenergy, and others will always be built on a strong foundation of fundamental plant biology research.

Download or read book New Horizons in Evolutionary Robotics written by Stéphane Doncieux and published by Springer. This book was released on 2011-02-14 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evolutionary Algorithms (EAs) now provide mature optimization tools that have successfully been applied to many problems, from designing antennas to complete robots, and provided many human-competitive results. In robotics, the integration of EAs within the engineer’s toolbox made tremendous progress in the last 20 years and proposes new methods to address challenging problems in various setups: modular robotics, swarm robotics, robotics with non-conventional mechanics (e.g. high redundancy, dynamic motion, multi-modality), etc. This book takes its roots in the workshop on "New Horizons in Evolutionary Design of Robots" that brought together researchers from Computer Science and Robotics during the IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS-2009) in Saint Louis (USA). This book features extended contributions from the workshop, thus providing various examples of current problems and applications, with a special emphasis on the link between Computer Science and Robotics. It also provides a comprehensive and up-to-date introduction to Evolutionary Robotics after 20 years of maturation as well as thoughts and considerations from several major actors in the field. This book offers a comprehensive introduction to the current trends and challenges in Evolutionary Robotics for the next decade.

Download or read book How to Overcome the Antibiotic Crisis written by Marc Stadler and published by Springer. This book was released on 2016-12-21 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on antibiotics research, a field of topical significance for human health due to the worrying increase of nosocomial infections caused by multi-resistant bacteria. It covers several basic aspects, such as the evolution of antibiotic resistance and the influence of antibiotics on the gut microbiota, and addresses the search for novel pathogenicity blockers as well as historical aspects of antibiotics. Further topics include applied aspects, such as drug discovery based on biodiversity and genome mining, optimization of lead structures by medicinal chemistry, total synthesis and drug delivery technologies. Moreover, the development of vaccines as a valid alternative therapeutic approach is outlined, while the importance of epidemiological studies on important bacterial pathogens, the problems arising from the excessive use of antibiotics in animal breeding, and the development of innovative technologies for diagnosing the “bad bugs” are discussed in detail. Accordingly, the book will appeal to researchers and clinicians alike.

Download or read book Natural Resource Year in Review written by and published by . This book was released on 1997 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book New Horizons in Earth Reinforcement written by Jun Otani and published by CRC Press. This book was released on 2023-05-31 with total page 917 pages. Available in PDF, EPUB and Kindle. Book excerpt: Earth reinforcement techniques are used worldwide, providing dependable solutions to a wide range of geotechnical engineering problems.Well-established earth reinforcement technologies are regularly augmented by new materials, innovative construction techniques and advances in design and analysis. Furthermore, reinforced earth structures are increasingly seen as expedient and economical techniques in disaster situations, such as earthquakes, flooding or tsunamis. NEW HORIZONS in EARTH REINFORCEMENT contains contributions from the 5th International Symposium on Earth Reinforcement, Kyushu, Japan, 14-16 November 2007, and presents the very latest earth reinforcement techniques and design procedures. The volume showcases advances in materials and emerging applications, with special emphasis on disaster mitigation and geoenvironmental issues. The book will be invaluable to academics and professionals in geotechnical engineering.

Download or read book Studies in Natural Products Chemistry written by Atta-ur- Rahman and published by Gulf Professional Publishing. This book was released on 1988 with total page 1278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of immunosuppressant FR901483 and biogenetically related TAN1251 alkaloids. -- -- Bioactive natural products from southern african marine invertebrates. -- Bioactive marine sesterterpenoids. -- Antimalarial lead compounds from marine organisms. -- Bioactive saponins with cancer related and immunomodulatory activity: Recent developments. -- Chemical and biological aspects of iridoid bearing plants of temperate region. -- Iridoids and secoiridoids from Oleaceae. -- Pharmacological activities of iridoids biosynthesized by route II. -- Chemistry and neurotrophic activity of seco-prezizaane- and anislactone-type -- sesquiterpenes from Illicium species. -- New insights into the bioactivity of cucurbitacins. -- Griseofulvin and other biologically active halogen containing compounds from fungi. -- Bioactive alkaloids of fungal origin. -- Chemistry and biological activities of naturally occurring phthalides. -- Chemistry and biological activity of polyisoprenylated benzophenone deriva ...

Download or read book Exploring and Engineering Plant Specialized Metabolism Latest Advances and New Horizons written by Thu Thuy Dang and published by Frontiers Media SA. This book was released on 2021-12-21 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biotechnology for the 21st Century written by National Science and Technology Council (U.S.). Biotechnology Research Subcommittee and published by . This book was released on 1995 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book New Horizons for a Data Driven Economy written by José María Cavanillas and published by Springer. This book was released on 2016-04-04 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book readers will find technological discussions on the existing and emerging technologies across the different stages of the big data value chain. They will learn about legal aspects of big data, the social impact, and about education needs and requirements. And they will discover the business perspective and how big data technology can be exploited to deliver value within different sectors of the economy. The book is structured in four parts: Part I “The Big Data Opportunity” explores the value potential of big data with a particular focus on the European context. It also describes the legal, business and social dimensions that need to be addressed, and briefly introduces the European Commission’s BIG project. Part II “The Big Data Value Chain” details the complete big data lifecycle from a technical point of view, ranging from data acquisition, analysis, curation and storage, to data usage and exploitation. Next, Part III “Usage and Exploitation of Big Data” illustrates the value creation possibilities of big data applications in various sectors, including industry, healthcare, finance, energy, media and public services. Finally, Part IV “A Roadmap for Big Data Research” identifies and prioritizes the cross-sectorial requirements for big data research, and outlines the most urgent and challenging technological, economic, political and societal issues for big data in Europe. This compendium summarizes more than two years of work performed by a leading group of major European research centers and industries in the context of the BIG project. It brings together research findings, forecasts and estimates related to this challenging technological context that is becoming the major axis of the new digitally transformed business environment.

Download or read book The Microbial Regulation of Global Biogeochemical Cycles written by Johannes Rousk and published by Frontiers E-books. This book was released on 2014-10-17 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global biogeochemical cycles of carbon and nutrients are increasingly affected by human activities. So far, modeling has been central for our understanding of how this will affect ecosystem functioning and the biogeochemical cycling of carbon and nutrients. These models have been forced to adopt a reductive approach built on the flow of carbon and nutrients between pools that are difficult or even impossible to verify with empirical evidence. Furthermore, while some of these models include the response in physiology, ecology and biogeography of primary producers to environmental change, the microbial part of the ecosystem is generally poorly represented or lacking altogether. The principal pool of carbon and nutrients in soil is the organic matter. The turnover of this reservoir is governed by microorganisms that act as catalytic converters of environmental conditions into biogeochemical cycling of carbon and nutrients. The dependency of this conversion activity on individual environmental conditions such as pH, moisture and temperature has been frequently studied. On the contrary, only rarely have the microorganisms involved in carrying out the processes been identified, and one of the biggest challenges for advancing our understanding of biogeochemical processes is to identify the microorganisms carrying out a specific set of metabolic processes and how they partition their carbon and nutrient use. We also need to identify the factors governing these activities and if they result in feedback mechanisms that alter the growth, activity and interaction between primary producers and microorganisms. By determining how different groups of microorganisms respond to individual environmental conditions by allocating carbon and nutrients to production of biomass, CO2 and other products, a mechanistic as well as quantitative understanding of formation and decomposition of organic matter, and the production and consumption of greenhouse gases, can be achieved. In this Research Topic, supported by the Swedish research councils' programme "Biodiversity and Ecosystem Services in a Changing Landscape" (BECC), we intend to promote this alternative framework to address how cycling of carbon and nutrients will be altered in a changing environment from the first-principle mechanisms that drive them – namely the ecology, physiology and biogeography of microorganisms – and on up to emerging global biogeochemical patterns. This novel and unconventional approach has the potential to generate fresh insights that can open up new horizons and stimulate rapid conceptual development in our basic understanding of the regulating factors for global biogeochemical cycles. The vision for the research topic is to facilitate such progress by bringing together leading scientists as proponents of several disciplines. By bridging Microbial Ecology and Biogeochemistry, connecting microbial activities at the micro-scale to carbon fluxes at the ecosystem-scale, and linking above- and belowground ecosystem functioning, we can leap forward from the current understanding of the global biogeochemical cycles.