Download or read book New Frontiers In Stress Research written by David Ben-Nathan and published by CRC Press. This book was released on 1998-07-28 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The stress response is an adaptive, complex, and essential process that serves to prepare an organism for the variety of dangers it may encounter. However, this same process may also be detrimental. The challenge of identifying the circumstances which alter the advantageous stress response to a damaging process has been taken up by scientists from various disciplines. The interdisciplinary focus on the modifications of brain functions as the medium for the immediate, as well as the long-term, effects of stress, enables a simultaneous analysis of the behavioral, histological, hormonal, and immunological processes involved. The dichotomy of the stress response is elucidated through the interactions of various neuronal sites, and the neurotransmitter and hormonal regulation of the central nervous system. Research on the interaction between stress and neuroimmunological processes is included and the implications of these stress effects to human conditions such as Post Traumatic Stress Disorder (PTSD), Alzheimer's disease, and memory impairment are addressed.
Download or read book Neuromodulation in Basic Translational and Clinical Research in Psychiatry written by Ryouhei Ishii and published by Frontiers Media SA. This book was released on 2020-01-20 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Brain Protection in Schizophrenia Mood and Cognitive Disorders written by Michael S. Ritsner and published by Springer Science & Business Media. This book was released on 2010-06-16 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroprotection is a novel perspective for the treatment of disorders that lead to neurodegeneration and disabilities as a result of deterioration of neurons due to apoptosis, oxidative stress, excitotoxicity, and other mechanisms. These mechanisms have implications not only for neurodegenerative disorders, but also for schizophrenia, mood and cognitive disorders. The purpose of this book is to provide an up-to-date overview of basic and clinical studies concerning the neuroprotective approach, mechanisms, and several compounds with neuroprotective properties that may contribute to more efficacious treatment of major mental health disorders. The book is divided into two sections. The first section serves as an introduction and overview of conceptual issues of the neuroprotective approach, and some neurobiological advances. Chapters in this section review definitions, perspectives, and issues that provide a conceptual base for the rest of the book. In addition, this part includes chapters in which the authors present and discuss the findings from basic studies of neurodegenerative mechanisms that are associated with the pathogenesis of major mental health disorders. The second section focuses on findings obtained from clinical trials with neuroprotective compounds, and neuromodulatory techniques. The take-home message is that principles of the neuroprotective approach may be applied to treatment of schizophrenia, mood and cognitive disorders. Contributors to this book are among the most active investigators and clinicians in the field who provide new perspectives not only clarifying ongoing controversies but also propose diverse aspects and new insights to neuroprotection. This book is intended for a broad readership, which includes a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, graduate students, and policy makers in the fields of mental health.
Download or read book Neuroinflammation written by Alireza Minagar and published by Elsevier. This book was released on 2010-12-17 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, and brain trauma as well as meningitis and contributes to the generation of pain. We are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage through tolerance to modulation and repair.This book discusses some of the more common neuro-inflammatory diseases. Topics covered include multiple sclerosis, optic neuritis and Susac syndrome. Comprehensive review of the latest developments in neuroinflammation Includes contributions from leading authorities
Download or read book Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity written by C. Jane Welsh and published by Springer Science & Business Media. This book was released on 2007-04-05 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a lucid summary of behavioral, neural and endocrine regulation of immune responses and of the effects of immune system activity on neural and endocrine functions and behavior. The underlying premise is that the brain and immune system represent a single, integrated system of defense. The discussion includes such topics and stress induced modulation of innate resistance and adaptive immunity in influenza viral infections.
Download or read book Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co morbidity Factors Part A written by and published by Elsevier. This book was released on 2023-10-01 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co-morbidity Factors, Volume 171 in the International Review of Neurobiology series, highlights new advances in the field with this new volume presenting interesting chapters on Neurodegenerative diseases, Stress induced exacerbation of Alzheimer's disease brain pathology is thwarted by co-administration of nanowired cerebrolysin and amyloid beta peptide antibodies with serotonin 5-HT6 receptor antagonist SB-39988, Nanowired delivery of dl-3-n-butylphthalide with antibodies to alpha synuclein potentiated neuroprotection in Parkinson's disease with emotional stress, Efficacy of invasive and non-invasive methods for the treatment of Parkinson ́s disease: nanodelivery and enriched environment, and much more. Other sections cover Sleep deprivation induced exacerbation of Parkinson's disease pathophysiology is attenuated by co-administration of nanowired cerebrolysin and serotonin-3 receptor antagonist ondansetron, Co-administration of DL-3-n-butylphthalide and neprilysin is neuroprotective in Alzheimer disease associated with brain injury, Stress and brain diseases, Pathophysiology of sleep deprivation enhances amyloid beta peptide and p-tau in the CSF and brain, Neuroprotective effects of nanowired delivery of multimodal drug cerebrolysin and monoclonal 5-HT antibodies, Prior heat exposure exacerbates brain blast injury, Neuroprotection by nanodelivery of cerebrolysin with serotonin 6 receptor antagonist SB-399885, the Effects of curcumin nanodelivery on several brain pathologies, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Internation Review on Neurobiology series Updated release includes the latest information on Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co-Morbidity Factors
Download or read book Molecular Mechanisms of Hormone Actions on Behavior written by Anne M. Etgen and published by Academic Press. This book was released on 2010-03-16 with total page 1100 pages. Available in PDF, EPUB and Kindle. Book excerpt: A single volume of 31 articles, Mechanisms of Hormone Actions on Behavior is an authoritative selection of relevant chapters from the Hormones Brain and Behavior 2e MRW, the most comprehensive source of neuroendocrinological information assembled to date (AP June 2009). The study of hormones as they impact the brain and, subsequently, behavior is a central topic in neuroscience, endocrinology and psychiatry. This volume offers an overview of neuroendocrinological topics, approaching the subject from the perspective of the mechanisms which control hormone actions on behavior. Female, male and stress hormones are discussed at the cellular, behavioral and developmental level, and sexual differentiation of the development of hormone-dependent neuronal systems, neuropeptides/neuromodulators, and steroid-inducedneuroplasticity are addressed. There is simply no other current single-volume reference with such comprehensive coverage and depth.Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 175 figures (over 50 in color). A collection of articles reviewing our fundamental knowledge of the mechanisms of neuroendocrinology, the book provides an essential, affordable reference for researchers, clinicians and graduate students in the area. The most comprehensive single-volume source of up-to-date data on the mechanisms behind neuroendocrinology, with review articles covering x,y z Chapters synthesize information otherwise dispersed across a number of journal articles and book chapters, thus saving researchers the time consuming process of finding and integrating this information themselves Offering outstanding scholarship, each chapter is written by an expert in the topic area and approximately 35% of chapters are written by international contributors Provides more fully vetted expert knowledge than any existing work with broad appeal for the US, UK and Europe, accurately crediting the contributions to research in those regions Heavily illustrated with 175 figures, approximately 54 in color Presents material in most visually useful form for the reader
Download or read book Principles of Molecular Neurosurgery written by Andrew Freese and published by Karger Medical and Scientific Publishers. This book was released on 2005-01-01 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt: The future of neurosurgery will be characterized by less invasive, molecular technologies that promise to revolutionize the field of neurosurgery and impact the treatment of additional neurological disorders, including neurometabolic diseases, stroke, dementias, affective and psychiatric diseases, movement disorders, epilepsy, and others. This book encompasses developing an understanding of the principles underlying the advent of novel molecular approaches to neurological and neurosurgical diseases. It Identifies key principles that will allow dramatic improvement in the treatment and outcomes of patients suffering from a varity of disorders affecting the central nervous system and spinal axis. This volume gives neurosurgeons an excellent understanding of the development of novel molecular and cellular technologies that will markedly change the way neurosurgery is practiced in the near future. It is also of special interest to neurologists, psychiatrists, physiatrists, spinal orthopaedic surgeons, neurobiologists and gene therapy research scientists.
Download or read book Blood Spinal Cord and Brain Barriers in Health and Disease written by Hari Shanker Sharma and published by Elsevier. This book was released on 2003-12-21 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent research into the anatomy and pathophysiology of the blood-brain and blood-spinal cord barriers suggests that a breakdown in these barriers can result in several diseases affecting the central nervous system (CNS). This book presents new findings in the area of blood-brain barrier research that suggest barriers play important roles in health and disease conditions. It also discusses the development of new drugs that can modulate the barrier function in the CNS and may provide new approaches to treating neurological diseases such as Alzheimer's disease and other motor neuron diseases, as well as spinal cord trauma. Key Features * Presents the recent progress made in the research on the blood-brain and spinal cord barrier * Contains numerous illustrations of light and electron micrographs * Includes Foreword written by two eminent researchers in the field, Milton Brightman and Jorge Cervos-Navarro
Download or read book Nanomedicine and Neuroprotection in Brain Diseases written by Hari Shanker Sharma and published by Elsevier. This book was released on 2021-09-22 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Progress in Brain Research series Updated release includes the latest information on the Neuropharmacology of Neuroprotection
Download or read book Brain Edema XI written by A.D. Mendelow and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain edema is found in a wide variety of clinical disorders including stroke, intracerebral haemorrhage, subarachnoid haemorrhage, head injury, brain tumors and hydrocephalus. This volume brings together clinical and basic scientists from all over the world. Their expertise in the understanding of brain edema and shifts in brain water compartments has led to a further significant step in our understanding of those diseases characterized by brain edema. This book has also drawn on the expertise of the International Advisory Board of the Brain Edema Society, who have carefully summarized each section, thus providing an easy-to-read summary of the latest advances in each subject. The book is therefore much more than a collection of papers: it represents a critical appraisal and puts each paper into modern scientific context. The greatest advances have come from the rapid development of modern imaging techniques, especially with magnetic resonance imaging (MRI). Imaging can now produce "water maps” and "metabolic profiles” that bring brain metabolism and water content right into every clinic with access to MRI. This book provides the background knowledge to understand these pathophysiological changes.
Download or read book Beyond the borders The gates and fences of Neuroimmune interaction written by Javier Velázquez-Moctezuma and published by Frontiers E-books. This book was released on 2014-10-10 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroimmunology is a rapidly growing emerging field at which two old sciences have converged to integrate two different types of responses into a single coherent response involving the coordinated action of both systems, neural and immune. During long time it was thought that both systems worked separately and in divergent pathways. The brain was considered an immunoprivileged site and the immune organs were deemed as independent of any neural influence and also of nervous innervation. Time has gone and has proven that the borders between both systems were merely artificial. Since the beginning of Neuroimmunology in the 1980s much work has been done to elucidate the gates and fences in neuro-immune interactions. Brain was shown to be under the continuous surveillance of the immune system, even under basal physiological conditions in the absence of any pathology. Likely, it was found a profuse nervous innervation of lymphoid organs and even of single immune cells. Gates for direct neural immune communication were found both centrally and peripherally. Centrally, the gates, but also the fences, were situated at the brain barriers, the blood-brain barrier and the blood-cerebrospinal fluid barrier, and at the circunventricular organs. Peripherally, the fences constituted the apparent diverse nature of molecules involved in neural and immune signaling; however, time proved that both system were capable of producing the same signaling molecules and also systematically responded to the molecules released by the other system. Therefore, the gates were open for direct neural-immune communication at the peripheral level. This Research Topic aimed to include original reports, reviews and technical reports regarding the description of the gates and fences in neural immune interactions. We intended to provide an extensive view of the mechanisms governing central and peripheral neural-immune interactions, and the role of the borders, the blood-neural barriers, in the regulation of the neural-immune communication.
Download or read book Depression and Dementia written by Suptendra Nath Sarbadhikari and published by Nova Publishers. This book was released on 2005 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many of the mechanisms of brain action, in health, as well as diseases like depression and dementia, are non-linear. The psychomotor theory can shed some light on the brain-mind-body interaction in health and disease. Specific neurotransmitters through their different receptor subtypes ultimately act along some final common pathway, in a lateralised fashion to produce depression and dementia. The currently available neurochemical and genetic evidences and their correlation with life events from population based studies, may be useful in screening susceptibility to dementia and depression. Further, criteria may be set up for susceptibility to these diseases and they might help designing early interventions in prevention of depression and dementia. The breakdown of the BBB (Blood brain barrier) through Heat Shock Protein (HSP) is also responsible for many neurodegenerative diseases. Aggressive and individualised management of patients suffering from depression and dementia may be the most promising gift of medical science and technology to humanity. Nonlinear dynamic analysis (NDA) of EEG (electroencephalography) may aid in the differential diagnosis of dementias. However, the methodologies have to be standardised further to make it clinically acceptable universally. ERPs (event related potentials in EEG) can be of great help in diagnosis and also assessing prognosis of dementias. Finally, fusion or hybrid techniques, especially those incorporating fMRI or functional magnetic resonance imaging (along with qEEG or quantitative EEG) can be of immense help in diagnosing, managing and predicting the prognosis of depression and dementia. This book discusses the above issues and offers an important update in the area of depression and dementia.
Download or read book Neural Plasticity and Memory written by Federico Bermudez-Rattoni and published by CRC Press. This book was released on 2007-04-17 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq
Download or read book Progress in Nanomedicine in Neurologic Diseases written by Hari Shanker Sharma and published by Springer Nature. This book was released on 2023-08-23 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the use of nanomedicine in the delivery of neuroprotective agents, including pharmacological drugs, stem cells, neurotrophic factors, monoclonal antibodies and enzymes to induce greater beneficial effects in neurologic diseases. Thus, the main purpose of the book is to explore the delivery of drugs either alone or in combination with stem cells to enhance neuroprotection in neurological diseases. Brain pathology associated with acute trauma such as head injury and brain blast injury can also be managed using novel treatment strategies. In addition, emphasis is made that standard patterns of brain pathology may be complicated with multiple comorbidity factors where one agent alone is not sufficient to induce brain protection. Enzymes and antibodies may help in combination and enhance the efficacy when administered through nanotechnology. Progress in Nanomedicine in Neurologic Diseases will encourage further research in the field of neuroprotection, brain injury, neurodegenerative diseases, neuropharmacology, neuropathology, and neurology. Students and researchers along with policy makers, teachers and health care professionals may also benefit from the findings of the book for enhanced patients care.
Download or read book Mineral Requirements for Military Personnel written by Institute of Medicine and published by National Academies Press. This book was released on 2006-07-21 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: The U.S. Army Health Risk Appraisal group surveyed 400,000 active duty U.S. Army personnel in the late 1990s to determine whether or not those personnel met the dietary objectives of Healthy People 2000 (HP2000), a national agenda for health promotion and disease prevention. As reported by Yore et al. (2000), Army personnel generally did not meet the HP2000 goals for nutrition even though significant progress had been made during 1991-1998. Although the specific aspects of diet that would be relevant to this Committee on Mineral Requirements for Cognitive and Physical Performance of Military Personnel are lacking, the findings from this survey suggest that there are dietary problems in the military population. The potential for adverse effects of marginal mineral deficiencies among soldiers engaged in training or military operations and the prospect of improving military performance through mineral intakes have spurred the military's interest in this area of nutrition. Mineral Requirements for Military Personnel provides background information on the current knowledge regarding soldiers' eating behaviors as well as on the physical and mental stress caused by military garrison training or operations. This report also offers facts on the mineral content of rations and its intake by military personnel and addresses the potential effects of nutrient deficiencies due to inadequate intake or higher requirements during military operations. Mineral Requirements for Military Personnel provides information and recommendations on the development and uses of MDRIs and a description of strategies to increase intake of specific minerals, whether via usual foods, fortification, or supplementation. This report features a description of the metabolism and needs for selected minerals by military personnel under garrison training, recommendations on mineral intake levels, and an assessment of mineral level adequacy in operational rations. This report also includes a prioritization of the research needed to answer information gaps and details of study designs required to gain such information.
Download or read book Hormones Brain and Behavior Online written by and published by Academic Press. This book was released on 2002-06-18 with total page 5944 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormones, Brain, and Behavior, Second Edition is a comprehensive work discussing the effect of hormones on the brain and, subsequently, behavior. This major reference work has 109 chapters covering a broad range of topics with an extensive discussion of the effects of hormones on insects, fish, amphibians, birds, rodents, and humans. To truly understand all aspects of our behavior, we must take every influence (including the hormonal influences) into consideration. Donald Pfaff and a number of well-qualified editors examine and discuss how we are influenced by hormonal factors, offering insight, and information on the lives of a variety of species. Hormones, Brain, and Behavior offers the reader comprehensive coverage of growing field of research, with a state-of-the-art overview of hormonally-mediated behaviors. This reference provides unique treatment of all major vertebrate and invertebrate model systems with excellent opportunities for relating behavior to molecular genetics. The topics cover an unusual breadth (from molecules to ecophysiology), ranging from basic science to clinical research, making this reference of interest to a broad range of scientists in a variety of fields. Available online exclusively via ScienceDirect. A limited edition print version is also available. Comprehensive coverage of a growing field of research Unique treatment of all major vertebrate and invertebrate model systems with excellent opportunites for relating behavior to molecular genetics Covers an unusual breadth ranging from molecules to ecophysiology, and from basic science to clinical research