Download or read book New Frontiers in genetics and biology written by Aliasghar Tabatabaei Mohammadi and published by Nobel Sciences. This book was released on with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book New Frontiers and Applications of Synthetic Biology written by Vijai Singh and published by Academic Press. This book was released on 2022-01-12 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Frontiers and Applications of Synthetic Biology presents a collection of chapters from eminent synthetic biologists across the globe who have established experience and expertise working with synthetic biology. This book offers several important areas of synthetic biology which allow us to read and understand easily. It covers the introduction of synthetic biology and design of promoter, new DNA synthesis and sequencing technology, genome assembly, minimal cells, small synthetic RNA, directed evolution, protein engineering, computational tools, de novo synthesis, phage engineering, a sensor for microorganisms, next-generation diagnostic tools, CRISPR-Cas systems, and more. This book is a good source for not only researchers in designing synthetic biology, but also for researchers, students, synthetic biologists, metabolic engineers, genome engineers, clinicians, industrialists, stakeholders and policymakers interested in harnessing the potential of synthetic biology in many areas. Offers basic understanding and knowledge in several aspects of synthetic biology Covers state-of-the-art tools and technologies of synthetic biology, including promoter design, DNA synthesis, DNA sequencing, genome design, directed evolution, protein engineering, computational tools, phage design, CRISPR-Cas systems, and more Discusses the applications of synthetic biology for smart drugs, vaccines, therapeutics, drug discovery, self-assembled materials, cell free systems, microfluidics, and more
Download or read book New Frontiers in Bryology written by Andrew J. Wood and published by Springer Science & Business Media. This book was released on 2013-03-20 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mosses (Bryophatea, Musci) are a diverse and widely distributed group of land plants. Mosses are attractive experimental plants because they exhibit the traditional attributes of good model systems (Le. ease of growth & maintenance, fast generation time, and amenable genetics) with the added advantage of a haploid gametophyte that allowed developmental mutants to be recovered with relative ease. In addition, mosses with the ability to tolerate extreme environmental conditions offer realistic models for the analysis of environmental stress-tolerance; particularly when compared to tracheophytes such as Arabidopsis thaliana in which these important plant phenotypes are either not clearly expressed or entirely lacking. And, in one of the most exciting developments in Plant Biology, efficient homologous recombination occurs in the moss Physcomitrella patens. The ability to perform efficient homologous recombination (Le. gene knock-outs) in P. patens is at present unique amongst all plants and represents an extremely powerful technique for the functional analysis of many plant genes. Over the past 5 years, a world-wide community of moss researchers has evolved. A highly successful "Moss" conference has been held annually (l998-Mumbai, India; 1999-Carbondale, IL, USA; 2000-Villars, Switzerland; 200l-0kazaki, Japan; 2002-Ambleside, UK; 2003-St. Louis, MO, USA) with "Moss 2004" planned to be held in Frieburg Germany. These conferences have been instrumental in the creation & development of strong collaborative ties, and the free exchange of both ideas and materials.
Download or read book Proteome Research New Frontiers in Functional Genomics written by Marc R. Wilkins and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in two-dimensional electrophoresis, protein microanalysis and bioinformatics have made the large-scale, systematic analysis of proteins and their post-translational modifications from any tissue or organism possible. This approach has acquired the name "Proteome Research", and can be considered as the core of functional genomics. The results of proteome analysis show which genes are expressed, how the protein products are modified, and how they interact, making proteome research of fundamental importance for the biologist, clinician, and pharmaceutical industry.
Download or read book New Frontiers in Chemical Biology written by Mark E. Bunnage and published by Royal Society of Chemistry. This book was released on 2011 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the new frontiers in chemical biology and describes their impact and future potential in drug discovery.
Download or read book Frontiers in Computational and Systems Biology written by Jianfeng Feng and published by Springer Science & Business Media. This book was released on 2010-06-14 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological and biomedical studies have entered a new era over the past two decades thanks to the wide use of mathematical models and computational approaches. A booming of computational biology, which sheerly was a theoretician’s fantasy twenty years ago, has become a reality. Obsession with computational biology and theoretical approaches is evidenced in articles hailing the arrival of what are va- ously called quantitative biology, bioinformatics, theoretical biology, and systems biology. New technologies and data resources in genetics, such as the International HapMap project, enable large-scale studies, such as genome-wide association st- ies, which could potentially identify most common genetic variants as well as rare variants of the human DNA that may alter individual’s susceptibility to disease and the response to medical treatment. Meanwhile the multi-electrode recording from behaving animals makes it feasible to control the animal mental activity, which could potentially lead to the development of useful brain–machine interfaces. - bracing the sheer volume of genetic, genomic, and other type of data, an essential approach is, ?rst of all, to avoid drowning the true signal in the data. It has been witnessed that theoretical approach to biology has emerged as a powerful and st- ulating research paradigm in biological studies, which in turn leads to a new - search paradigm in mathematics, physics, and computer science and moves forward with the interplays among experimental studies and outcomes, simulation studies, and theoretical investigations.
Download or read book The Applications of New Multi Locus GWAS Methodologies in the Genetic Dissection of Complex Traits written by Yuan-Ming Zhang and published by Frontiers Media SA. This book was released on 2019-06-19 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome-Wide Association Studies (GWAS) are widely used in the genetic dissection of complex traits. Most existing methods are based on single-marker association in genome-wide scans with population structure and polygenic background controls. To control the false positive rate, the Bonferroni correction for multiple tests is frequently adopted. This stringent correction results in the exclusion of important loci, especially for GWAS in crop genetics. To address this issue, multi-locus GWAS methodologies have been recommended, i.e., FASTmrEMMA, ISIS EM-BLASSO, mrMLM, FASTmrMLM, pLARmEB, pKWmEB and FarmCPU. In this Research Topic, our purpose is to clarify some important issues in the application of multi-locus GWAS methods. Here we discuss the following subjects: First, we discuss the advantages of new multi-locus GWAS methods over the widely-used single-locus GWAS methods in the genetic dissection of complex traits, metabolites and gene expression levels. Secondly, large experiment error in the field measurement of phenotypic values for complex traits in crop genetics results in relatively large P-values in GWAS, indicating the existence of small number of significantly associated SNPs. To solve this issue, a less stringent P-value critical value is often adopted, i.e., 0.001, 0.0001 and 1/m (m is the number of markers). Although lowering the stringency with which an association is made could identify more hits, confidence in these hits would significantly drop. In this Research Topic we propose a new threshold of significant QTN (LOD=3.0 or P-value=2.0e-4) in multi-locus GWAS to balance high power and low false positive rate. Thirdly, heritability missing in GWAS is a common phenomenon, and a series of scientists have explained the reasons why the heritability is missing. In this Research Topic, we also add one additional reason and propose the joint use of several GWAS methodologies to capture more QTNs. Thus, overall estimated heritability would be increased. Finally, we discuss how to select and use these multi-locus GWAS methods.
Download or read book Discovering the Individual written by Jean Hamburger and published by W. W. Norton. This book was released on 1978 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Scientific Frontiers in Developmental Toxicology and Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2000-12-21 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
Download or read book Making Sense of Genes written by Kostas Kampourakis and published by Cambridge University Press. This book was released on 2017-03-30 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: What are genes? What do genes do? These seemingly simple questions are in fact challenging to answer accurately. As a result, there are widespread misunderstandings and over-simplistic answers, which lead to common conceptions widely portrayed in the media, such as the existence of a gene 'for' a particular characteristic or disease. In reality, the DNA we inherit interacts continuously with the environment and functions differently as we age. What our parents hand down to us is just the beginning of our life story. This comprehensive book analyses and explains the gene concept, combining philosophical, historical, psychological and educational perspectives with current research in genetics and genomics. It summarises what we currently know and do not know about genes and the potential impact of genetics on all our lives. Making Sense of Genes is an accessible but rigorous introduction to contemporary genetics concepts for non-experts, undergraduate students, teachers and healthcare professionals.
Download or read book The Life Sciences written by and published by National Academies. This book was released on 1970-01-01 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book New Perspectives on the Biology of Nectaries and Nectars written by Clay Carter and published by Frontiers Media SA. This book was released on 2019-08-27 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: The number of currently known, described and accepted plant species is ca 374,000, of which approximately 295,00 (79%) are angiosperms. Almost 90% of this huge number of flowering plants is pollinated by animals (mostly insects) via nectar-mediated interactions. Notably, three-fourths of the leading global crop plants produce nectar and are animal pollinated, which is estimated to account for one-third of human food resources. Nectar can also be produced on tissues outside of flowers, by so-called extrafloral nectaries, and commonly mediate interactions with ‘body-guard’ ants and other pugnacious insects that defend the plant from herbivores. Extrafloral nectar is present in almost 4,000 plant species, a majority of them in the angiosperms. This brief summary on the occurrence of nectar in the plant kingdom is just to highlight that nectar has a fundamental role in two basal functions that allow the maintenance of our ecosystems: sexual plant reproduction and protection of plants from herbivory. Despite playing essential ecological and evolutionary functions, our current knowledge about nectar is largely incomplete; however, new research directions and perspectives on nectaries and nectars have arisen in recent years. In the last two decades, there were only a few ‘moments’ in which nectar was the main character in international meetings or in published books. In 2002, the first (and only) international meeting “Nectar and nectary: from biology to biotechnology” dedicated exclusively to nectar and nectaries was held in Italy (Montalcino, Siena) and in 2003 the proceedings were published in a special volume of Plant Systematics and Evolution (238, issue 1-4). In 2007, the book Nectar and Nectaries was published (Springer) with most of the contributions provided by authors that attended the meeting in Italy. Another book dedicated to nectar was published in 2015 (Nectar: Production, Chemical Composition and Benefits to Animals and Plants, Nova Science Publishers) covering aspects mainly related to nectar chemical composition and plant-pollinator interactions. Similarly, symposia focused on nectar have been organized within the International Botanical Congress in 2011 and 2017. Considering that the last few years has yielded essential developments in the understanding of nectar biology, we thought now is the moment to further stimulate research on this important topic. This aim has been met through 18 papers published in our Research Topic New Perspectives on the Biology of Nectaries and Nectars, with subjects spanning evolution and ecology to nectar chemistry and nectary structure.
Download or read book Plant Systems Biology written by Sacha Baginsky and published by Springer Science & Business Media. This book was released on 2007-06-25 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume aims to provide a timely view of the state-of-the-art in systems biology. The editors take the opportunity to define systems biology as they and the contributing authors see it, and this will lay the groundwork for future studies. The volume is well-suited to both students and researchers interested in the methods of systems biology. Although the focus is on plant systems biology, the proposed material could be suitably applied to any organism.
Download or read book New Frontiers in the Study of Gene Functions written by George Poste and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Epigenetics Revolution written by Nessa Carey and published by Columbia University Press. This book was released on 2012-03-06 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field's arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.
Download or read book New Frontiers in Nanochemistry Concepts Theories and Trends 3 Volume Set written by Mihai V. Putz and published by CRC Press. This book was released on 2022-05-30 with total page 1479 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Frontiers in Nanochemistry: Concepts, Theories, and Trends, 3-Volume Set explains and explores the important fundamental and advanced modern concepts from various areas of nanochemistry and, more broadly, the nanosciences. This innovative and one-of-a kind set consists of three volumes that focus on structural nanochemistry, topological nanochemistry, and sustainable nanochemistry respectively, collectively forming an explicative handbook in nanochemistry. The compilation provides a rich resource that is both thorough and accessible, encompassing the core concepts of multiple areas of nanochemistry. It also explores the content through a trans-disciplinary lens, integrating the basic and advanced modern concepts in nanochemistry with various examples, applications, issues, tools, algorithms, and even historical notes on the important people from physical, quantum, theoretical, mathematical, and even biological chemistry.
Download or read book Viruses Genetic Exchange and the Tree of Life written by Arshan Nasir and published by Frontiers Media SA. This book was released on 2020-01-23 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt:
