Download or read book New Directions in the Management of Status Epilepticus written by Batool F. Kirmani and published by Frontiers Media SA. This book was released on 2019-02-06 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: Status Epilepticus (SE) is a neurological emergency and has high morbidity and mortality. The International League Against Epilepsy (ILAE) recently updated their definition to specify that, “SE is a condition resulting either from the failure of the mechanisms responsible for seizure termination or from the initiation of mechanisms, which lead to abnormally, prolonged seizures.” Such phenomena can lead to long-term neurological complications due to neuronal death, glia, neurological injury, aberrant neuroplasticity, oxidative stress and inflammation, and alteration of neuronal networks. Depending upon the type and duration of SE, these mechanisms are quite variable. Therefore, in response to the updated definition of SE, novel avenues of research are required to address the specified involvement of the underlying mechanisms and pathophysiology resulting in the development of and outcomes from SE. Improving the basic science understanding of SE will facilitate essential clinical trials. One can envision such experiments to include device and compound-based technological interventions directed at aborting the seizure activity and improving clinical outcomes. Benzodiazepines remain one of the cornerstones of treatment, and studies are underway to study new delivery options, including intranasal, buccal, and intramuscular midazolam, in addition to rectal diazepam, with the goal of aborting the seizure activity outside the hospitals, as rapidly as possible. Approved and off-label anticonvulsants, such as phenytoin, phenobarbital, valproate, topiramate, levetiracetam, lacosamide, steroids, immunosuppressants, and neuroprotective compounds, have also shown some efficacy at treating SE. However, substantial challenges remain in optimally managing SE and minimizing the short- and long-term complications. Such difficulties can be overcome by innovative approaches targeting the underlying mechanisms of neuronal excitability, glia, neuronal death, neuroplasticity, oxidative stress, inflammation, and neuroinflammation.

Download or read book Pediatric Neurocritical Care written by Nicholas S. Abend, MD and published by Demos Medical Publishing. This book was released on 2012-11-28 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Pediatric Neurocritical Care is by far the most comprehensive book I have read dealing with this topic... This text will provide an excellent reference for those interested in the pediatric intensive care cases or pediatrics in general. It is written very well and is chock-full of information that Practioners in a pediatric ICU setting would use." --Donna Jacobs, R. EEG T., CNIM, The Neurodiagnostic Journal Caring for children with neurocritical illness often requires multi-specialty collaboration and the understanding of an ever-expanding body of data. This book gives clinicians the up-to-date, concise, and clinically relevant guidance they need to provide optimal care to children with these acute neurologic disorders. The chapters in Pediatric Neurocritical Care are authored by experts in each individual topic, and co-edited by a neurologist and intensivist to ensure that all topics have been fully addressed from both perspectives. The book covers the complete continuum of care from assessment, monitoring, and condition specific management through rehabilitation. Early chapters present differential diagnosis and management approaches to common overarching problems such as coma, headache, and elevated intracranial pressure, followed by chapters focusing on the evaluation and management of specific conditions including traumatic brain injury, stroke, seizures, central nervous system infections, and demyelinating disorders. The final chapters address important associated psychological, social, and ethical issues. To reflect the full spectrum of specialties involved in the burgeoning field of pediatric neurocritical care, the book brings together an international group of experts from multiple disciplines including critical care medicine, anesthesiology, neurology, neurosurgery, rehabilitation medicine, psychology, and pediatric subspecialties. Pediatric Neurocritical Care features: Every topic is addressed from a neurologic and critical care perspective. Comprehensive coverage includes the evaluation of common overarching problems and management of specific conditions, in addition to discussion of related psychological, ethical, and social issues. Chapters are written by internationally known experts from the fields of critical care medicine, anesthesiology, neurology, neurosurgery, rehabilitation medicine, and many affiliated specialties.

Download or read book Neurocritical Care written by Andrew M. Naidech and published by Cambridge University Press. This book was released on 2022-06-09 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Events in a neurological intensive care unit are not always predictable and patients can often be unstable. This practical manual is a clear and concise guide for recognising and managing neurological emergencies. Each chapter covers a crucial topic in neurocritical care, from understanding the pathophysiology of various neurological diseases, to neuroradiology used in diagnosis, and best practice for difficult decision making in the ICU. A variety of conditions are described such as haemorrhage (intracerebral, subdural, and subarachnoid), seizures, trauma and temperature dysregulation. An international team of experts have contributed chapters, providing a breadth of experience and knowledge for readers. This is an invaluable guide for clinicians on the front line of caring for patients with neurological emergencies who need life-saving answers quickly.

Download or read book Models of Seizures and Epilepsy written by Asla Pitkänen and published by Academic Press. This book was released on 2017-06-14 with total page 1178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. Provides a comprehensive reference detailing animal models of epilepsy and seizure Offers insights on the use of novel technologies that can be applied in experimental epilepsy research Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments

Download or read book Atlas of EEG in Critical Care written by Lawrence J. Hirsch and published by John Wiley & Sons. This book was released on 2011-08-17 with total page 639 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the population ages, technology improves, intensive care medicine expands and neurocritical care advances, the use of EEG monitoring in the critically ill is becoming increasingly important. This atlas is a comprehensive yet accessible introduction to the uses of EEG monitoring in the critical care setting. It includes basic EEG patterns seen in encephalopathy, both specific and non-specific, nonconvulsive seizures, periodic EEG patterns, and controversial patterns on the ictal–interictal continuum. Confusing artefacts, including ones that mimic seizures, are shown and explained, and the new standardized nomenclature for these patterns is included. The Atlas of EEG in Critical Care explains the principles of technique and interpretation of recordings and discusses the techniques of data management, and 'trending' central to long-term monitoring. It demonstrates applications in multi-modal monitoring, correlating with new techniques such as microdialysis, and features superb illustrations of commonly observed neurologic events, including seizures, hemorrhagic stroke and ischaemia. This atlas is written for practitioners, fellows and residents in critical care medicine, neurology, epilepsy and clinical neurophysiology, and is essential reading for anyone getting involved in EEG monitoring in the intensive care unit.

Download or read book Textbook of Neuroanesthesia and Neurocritical Care written by Hemanshu Prabhakar and published by Springer. This book was released on 2019-04-15 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume book offers a comprehensive guide to anesthetic management and critical care management in neurosurgical and neurological patients. This first volume focuses on neuroanesthesia. The book begins with basic information on neuroanesthesia, extensively discussing the anatomy of the brain and spine, physiology and relevant pharmacology. Special considerations for pregnant, pediatric and geriatric patients are covered in separate chapters. Each neurosurgical condition is discussed in a standard format relevant for neurosurgical patients, and each chapter, prepared by experts in the field, includes ample illustrations and flowcharts. Information is also provided on the latest evidence-based approaches, robotic surgery and gene therapy. The book offers a valuable resource for all residents, fellows and trainees in the fields of neuroanesthesia and anesthesia; it will also benefit practitioners and consultants.

Download or read book Oh s Intensive Care Manual written by Andrew D. Bersten and published by Elsevier Health Sciences. This book was released on 2009-01-01 with total page 1292 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sixth edition provides practical, concise information on all aspects of intensive care. Written in a clear and accessible style and now for the first time presented in colour throughout, this book enables the user to manage a patient in an ICU setting effectively without recourse to large text/reference works or specialized monographs. This thoroughly revised and updated edition reflects the best and most current practice from leading centres in Australia, the UK and Western Europe. Information on management and treatment of conditions is balanced by pathophysiological and pharmacological background. This is not just a "cook book" of procedures. It provides all of the essential information for candidates wishing to pass professional examinations. Addition of colour throughout to highlight summary boxes, tables, charts and flow diagrams.Will make key information more accessible, easier and faster to retrieve. Pitfalls in treatment and management emphasized in each chapter.Providers the user with expert advice on practical issues that will be encountered on a day-to-day basis in the ICU. Keeps the user abreast of the latest developments in diagnosis and management.

Download or read book Status Epilepticus written by Simon Shorvon and published by Cambridge University Press. This book was released on 1994-07-21 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: An invaluable reference work comprehensively reviewing current knowledge and treatment of Status Epilepticus.

Download or read book Oh s Intensive Care Manual E Book written by Andrew D Bersten and published by Elsevier Health Sciences. This book was released on 2008-12-05 with total page 1292 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sixth edition of Oh’s Intensive Care Manual provides practical, concise information on all aspects of intensive care. Written in a clear and accessible style and now for the first time presented in colour throughout, this book enables the user to manage a patient in an ICU setting effectively without recourse to large text/reference works or specialized monographs. This thoroughly revised and updated edition reflects the best and most current practice from leading centres in Australia, the UK and Western Europe. Although primarily intended for the trainee and practitioner in intensive care, nurses and other allied health professionals will find that this is an invaluable tool in helping to deal with a broad spectrum of conditions encountered in the ICU. Represents a consensus of practice/standard of care in Australia/NZ, UK and Europe. Treatment guidelines are authoritative since they follow those that are Recommended/laid down by Professional societies. Comprehensive, covers all important areas of intensive care medicine. Provides a single resource that will cover everything that a user will need to know during the course of an ICU rotation. No need to refer to a larger textbook. Information on management and treatment of conditions is balanced by pathophysiological and pharmacological background. This is not just a "cook book" of procedures. It provides all of the essential information for candidates wishing to pass professional examinations. Covers the paediatric as well as the adult patient in the ICU. Provides quick access and practical guidance for all clinical scenarios. Extensive list of key references most taken from the last three years. Helps trainees and practitioners prepare for case conference/presentations. Addition of colour throughout to highlight summary boxes, tables, charts and flow diagrams.Will make key information more accessible, easier and faster to retrieve. Line drawings extensively re-done in colour throughout.Will improve the user’s understanding of the physiological processes under discussion. 5-10 Key points added at end of chapters. Will provide the user with a useful summary of the essential bottom line information. Pitfalls in treatment and management emphasized in each chapter.Providers the user with expert advice on practical issues that will be encountered on a day-to-day basis in the ICU. Includes the most current classification and “clinical scoring schemes. Keeps the user abreast of the latest developments in diagnosis and management.

Download or read book Epilepsy and Brain Tumors written by Herbert B. Newton and published by Elsevier. This book was released on 2015-03-06 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patients with brain tumor-related epilepsy (BTRE) suffer from two serious pathologies simultaneously – a brain tumor and a secondary form of epilepsy. Although there has been remarkable progress in BTRE research in recent years, it remains an on-going challenge for clinicians and continues to stimulate much debate in the scientific community. This volume is the first to be completely dedicated to BTRE, and in doing so it explores issues faced by the health care team as well as some of the novel and promising directions that future research may take. Epilepsy and Brain Tumors is not only a complete reference on BTRE but also a practical guide based on clinical experiences, with a comprehensive collection of presentations from international experts who share some of the latest discoveries and their approaches to tackling a wide range of difficult and complex issues. Includes coverage of epidemiology, pathology and treatment of both primary and metastatic brain tumors Offers additional insight into supportive care, incidence in children, focal epileptogenesis, clinical evaluation, antiepileptic drugs, surgical treatment, cognitive rehabilitation, and more Chapters authored and edited by leaders in the field around the globe – the broadest, most expert coverage available

Download or read book The Child with Epilepsy written by United States. Children's Bureau and published by . This book was released on 1961 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Seizures and Epilepsy written by Jerome Engel Jr and published by Oxford University Press. This book was released on 2013-01-31 with total page 737 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of 'Seizures and Epilepsy' is completely revised, due to tremendous advances in the understanding of the fundamental neuronal mechanisms underlying epileptic phenomena, as well as current diagnosis and treatment, which have been heavily influenced over the past several decades by seminal neuroscientific developments, particularly the introduction of molecular neurobiology, genetics, and modern neuroimaging. This resource covers a broad range of both basic and clinical epileptology.

Download or read book Brain Disorders in Critical Illness written by Robert D. Stevens and published by Cambridge University Press. This book was released on 2013-09-19 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain dysfunction is a major clinical problem in intensive care, with potentially debilitating long-term consequences for post-ICU patients of any age. The resulting extended length of stay in the ICU and post-discharge cognitive dysfunction are now recognized as major healthcare burdens. This comprehensive clinical text provides intensivists and neurologists with a practical review of the pathophysiology of brain dysfunction and a thorough account of the diagnostic and therapeutic options available. Initial sections review the epidemiology, outcomes, relevant behavioral neurology and biological mechanisms of brain dysfunction. Subsequent sections evaluate the available diagnostic options and preventative and therapeutic interventions, with a final section on clinical encephalopathy syndromes encountered in the ICU. Each chapter is rich in illustrations, with an executive summary and a helpful glossary of terms. Brain Disorders in Critical Illness is a seminal reference for all physicians and neuroscientists interested in the care and outcome of severely ill patients.

Download or read book Netter s Neurology E Book written by Jayashri Srinivasan and published by Elsevier Health Sciences. This book was released on 2019-02-25 with total page 839 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perfect for residents, medical students, generalists, nurses, and other healthcare professionals who need a practical, working knowledge of neurology, Netter's Neurology, 3rd Edition, provides a concise overview highlighted by unique, memorable Netter illustrations. This award-winning visual resource showcases the well-known work of Frank H. Netter, MD, and his successor, Carlos Machado, MD, a physician who has created clear, full-color illustrations in the Netter tradition. Offers a quick and memorable summary of general neurology and its intersection with internal medicine, neurosurgery, ophthalmology, psychiatry, and orthopaedics. Concise text is presented in a templated format for fast, easy access to information. Features more than 450 Netter and Netter-style images that highlight anatomy, pathophysiology, and clinical presentation related to neuroanatomical and neurologic concepts. Helps you make correlations between anatomy, pathology, physiology, and pharmacology in a clinical setting. Clinical vignettes throughout provide real-world applications to each topic. Features new chapters on Laboratory Evaluation in Neurology; Neuroimaging in Neurologic Disorders; and Neurologic Emergencies and Critical Care. Presents the underlying anatomy in living patients through neuroimaging coverage, including MR, CT, and PET.

Download or read book Refractory Status Epilepticus written by Xuefeng Wang and published by Springer. This book was released on 2017-09-05 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to offer the accumulated fertile experience of treating drug-resistant epileptic patients collected over the past few decades, focusing on aspects of neurology, neurosurgery, emergency care, critical care medicine and basic medical research. Refractory status epilepticus is one of the most common severe and acute diseases in neurology and neurocritical care; it is also the main cause of death in epileptic patients. In the context of prevention and treatment processes, it is not only necessary to terminate epileptic seizures, but to also address the disruption of the patient’s internal environment and provide critical life support. Effective treatment calls for multi-disciplinary support from neurology, neurosurgery, emergency care, critical care medicine, and other fields. Further, since the clinical features of epileptic seizure are not specific, it is necessary to differentiate it from other diseases that produce convulsions, disorders of consciousness, syncope, mental and behavioral disorders, myoclonus, etc., to avoid misdiagnosis. In this book, it comprehensively and systematically describes the basic knowledge as well as prevention and treatment tips, providing an invaluable reference resource for medical students and professionals in neurology, neurosurgery, emergency care and critical care medicine.

Download or read book The Causes of Epilepsy written by Simon Shorvon and published by Cambridge University Press. This book was released on 2019-05-02 with total page 1013 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanded and revised, this unique book provides concise descriptions of the many causes of epilepsy, for use in clinical practice.

Download or read book Insights in Brain Disease Mechanisms 2021 written by Detlev Boison and published by Frontiers Media SA. This book was released on 2022-11-21 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: