Download or read book New Developments in Epstein Barr Virus Research written by Constantine S. Umar and published by Nova Publishers. This book was released on 2006 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epstein-Barr virus, frequently referred to as EBV, is a member of the herpes virus family and one of the most common human viruses. The virus occurs world-wide, and most people become infected with EBV sometime during their lives. In the United States, as many as 95 per cent of adults between 35 and 40 years of age have been infected. Infants become susceptible to EBV as soon as maternal antibody protection (present at birth) disappears. Many children become infected with EBV, and these infections usually cause no symptoms or are indistinguishable from the other mild, brief illnesses of childhood. In the United States and in other developed countries, many persons are not infected with EBV in their childhood years. When infection with EBV occurs during adolescence or young adulthood, it causes infectious mononucleosis 35 per cent to 50 per cent of the time. EBV also establishes a lifelong dormant infection in some cells of the body's immune system. A late event in a very few carriers of this virus is the emergence of Burkitt's lymphoma and nasopharyngeal carcinoma. This new book presents leading research from around the world in this field.
Download or read book The Epstein Barr Virus written by M. A. Epstein and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Epstein-Barr virus was discovered 15 years ago. Since that time an immense body of information has been accumu lated on this agent which has come to assume great signifi cance in many different fields of biological science. Thus, the virus has very special relevance in human medicine and oncology, in tumor virology, in immunology, and in mole cular virology, since it is the cause of infectious mononu cleosis and also the first human cancer virus, etiologically related to endemic Burkitt's lymphoma and probably to nasopharyngeal carcinoma. In addition, continuous human lymphoid cell lines initiated and maintained by the transform ing function of the virus genome provide a laboratory tool with wide and ever-growing applications. Innumerable papers on the Epstein-Barr virus have ap peared over recent years and reports of work with this agent now constitute a veritable flood. The present book provides the first and only comprehensive, authoritative over-view of all aspects of the virus by authors who have been the original and major contributors in their particular disciplines. A complete and up-to-date survey of this unique and important agent is thus provided which should be of great interest to experts, teachers, and students engaged in cancer research, virology, immunology, molecular biology, epide miology, and cell culture. Where topics have been dealt with from more than one of these viewpoints, some inevitable overlap and duplication has resulted; although this has been kept to a minimum, it has been retained in some places because of positive usefulness.
Download or read book Vaccines for the 21st Century written by Institute of Medicine and published by National Academies Press. This book was released on 2001-02-21 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vaccines have made it possible to eradicate the scourge of smallpox, promise the same for polio, and have profoundly reduced the threat posed by other diseases such as whooping cough, measles, and meningitis. What is next? There are many pathogens, autoimmune diseases, and cancers that may be promising targets for vaccine research and development. This volume provides an analytic framework and quantitative model for evaluating disease conditions that can be applied by those setting priorities for vaccine development over the coming decades. The committee describes an approach for comparing potential new vaccines based on their impact on morbidity and mortality and on the costs of both health care and vaccine development. The book examines: Lessons to be learned from the polio experience. Scientific advances that set the stage for new vaccines. Factors that affect how vaccines are used in the population. Value judgments and ethical questions raised by comparison of health needs and benefits. The committee provides a way to compare different forms of illness and set vaccine priorities without assigning a monetary value to lives. Their recommendations will be important to anyone involved in science policy and public health planning: policymakers, regulators, health care providers, vaccine manufacturers, and researchers.
Download or read book Human Herpesviruses written by Ann Arvin and published by Cambridge University Press. This book was released on 2007-08-16 with total page 1325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.
Download or read book Epstein Barr Virus written by and published by BoD – Books on Demand. This book was released on 2021-12-22 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epstein-Barr virus (EBV) is a fascinating microorganism, as a “double-facetted” viral agent. After primary infection, it can persist throughout a person’s lifetime in a latent form, from which it can reactivate following specific stimuli (i.e., immunodepression). Unlike other herpesviruses, EBV reactivates a countless number of times with such a high replication rate that it is unable to be controlled by conventional anti-herpesvirus drugs. Moreover, for various reasons, no vaccine is currently available in the market. This book presents a comprehensive overview of EBV, including information on its potential for oncogenic activity, its various isolates, and possible vaccine candidates.
Download or read book Epstein Barr Virus EBV written by Jan Styczynski and published by Nova Science Publishers. This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Epstein-Barr Virus (EBV), also known as Human Herpes Virus 4, has been identified and described as the etiological agent of infectious mononucleosis. It is the first human virus found to be implicated in oncogenesis. EBV is associated with a number of biologically diverse cancers, mainly lymphoproliferations of B-cell origin. With the development of basic research and clinical medicine, new ideas related to the pathogenesis and clinical aspects of EBV-associated diseases have arisen recently. A significant progress in the number of hematopoietic stem cell and solid organ transplantations performed world-wide, involving high-risk patients, has contributed to an increase in the development of EBV-associated malignant post-transplant lymphoproliferative disorders. In the stem cell transplant setting, a post-transplant lymphoproliferative disorder has in most cases the nature of a secondary cancer. Apart from post-transplant lymphoproliferative disorders, other types of lymphoproliferative disorders are recognised and presented in this book.
Download or read book Epstein Barr Virus Infections Advances in Research and Treatment 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epstein-Barr Virus Infections: Advances in Research and Treatment: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Epstein-Barr Virus Infections in a compact format. The editors have built Epstein-Barr Virus Infections: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Epstein-Barr Virus Infections in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Epstein-Barr Virus Infections: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Cancer Virus written by Dorothy H. Crawford and published by Oxford University Press, USA. This book was released on 2014-02 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the story of the discovery of the first human cancer virus. Through intriguing accounts that include some remarkable characters and individual stories from around the globe - including the UK, Africa, USA, and China - it tells the story of the Epstein-Barr virus and the understanding of its connections to a variety of other diseases.
Download or read book Epstein Barr Virus Volume 2 written by Christian Münz and published by Springer. This book was released on 2015-10-01 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epstein Barr virus (EBV) was discovered as the first human tumor virus around 50 years ago. Since its discovery in Burkitt’s lymphoma it has been associated with various other malignancies, infectious mononucleosis and even autoimmune diseases. The two book volumes on EBV summarize the first 50 years of research on this tumor virus, starting with historical perspectives on discovery, oncogenicity and immune control, reviewing the role that the virus plays in the various associated diseases and concluding with a discussion on how the immune system keeps persistent EBV infection under control in healthy EBV carriers and can be used to treat EBV associated diseases. The respective 32 chapters are written by international experts from three continents for health care providers, biomedical researchers and patients that are affected by EBV. The assembled knowledge should help to understand EBV associated diseases better and to develop EBV specific vaccination in the near future.
Download or read book Epstein Barr Virus Infections Advances in Research and Treatment 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 35 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epstein-Barr Virus Infections—Advances in Research and Treatment: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Epstein-Barr Virus Infections in a compact format. The editors have built Epstein-Barr Virus Infections—Advances in Research and Treatment: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Epstein-Barr Virus Infections in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Epstein-Barr Virus Infections—Advances in Research and Treatment: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book The Epstein Barr Virus written by Michael Anthony Epstein and published by . This book was released on 1986 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Epstein Barr Virus and Associated Diseases written by Thomas Tursz and published by John Libbey Eurotext. This book was released on 1993 with total page 870 pages. Available in PDF, EPUB and Kindle. Book excerpt: Text in English & French. This book gathers together all the most recent world-wide knowledge in the various fields of research into the Epstein-Barr virus (EBV), from the most fundamental subjects (virology, molecular and cellular biology and immunology) through epidemiology, pathological anatomy, clinical research and therapeutics. Featured in the book are highly original chapters dealing with malignant lymphomas in AIDS patients, detection and prevention in developing countries, formulation of an anti-EBV vaccine. This comprehensive and clearly written book is a valuable and essential tool for all researchers and clinicians.
Download or read book Development of Epstein Barr Virus Vaccines written by Andrew J. Morgan and published by Springer. This book was released on 1995 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about the development of the Epstein-Barr virus vaccine which may ultimately eliminate or reduce the incidence of the cancers associated with this virus in humans. These include nasopharyngial carcinoma, endemic Burkitts lymphoma and certain lymphomas which occur with a relatively high frequency in immunosuppressed patients and AIDS sufferers. Such vaccines may also be deployed in the prevention of infectious mononucleosis, a disease which, although rarely fatal, has a significant social and economic impact on the young adult population in the Western World. Several candidate vaccines based on recombinant viral envelope glycoproteins and a range of viral vectors have been evaluated in a primate animal model of lymphoma induced by the virus.
Download or read book Immunosurveillance Immunodeficiencies and Lymphoproliferations written by S.H. Oertel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers lymphoproliferative disorders in patients with congenital or acquired immunodeficiencies. Acquired immunodeficiencies are caused by infections with the human immunodeficiency virus or arise following immunosuppressive therapy administered after organ transplantation or to treat connective tissue diseases such as rheumatoid arthritis. It was recently discovered that various diseases or therapeutic modalities that induce a state of immunosuppression may cause virally driven lymphoproliferations. This book summarizes for the first time this group of immunodeficiency-associated lymphoproliferations.
Download or read book Epstein Barr Virus New Insights for the Healthcare Professional 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-10 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epstein-Barr Virus: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Epstein-Barr Virus. The editors have built Epstein-Barr Virus: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Epstein-Barr Virus in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Epstein-Barr Virus: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Epstein Barr Virus and Associated Diseases written by P.H. Levine and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 695 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been slightly more than two decades since the Epstein-Barr virus (EBV) was discovered by Prof. M.A. Epstein and his colleagues at the University of Bristol in their search for the causative agent of Burkitt's lymphoma. For several years EBV was a "virus in search of a disease." The first documentation that EBV was pathogenic for humans was in 1969 when Drs. Gertrude and Werner Henle identified it as the causative agent for infectious mononucleosis. Seroepidemiologic and biochemical studies subsequently linked EBV to Burkitt's lymphoma (BL), nasopharyngeal carcinoma (NPC), and more recently to the X-linked lymphoproliferative syndrome. With its widespread pattern of infection and a predilection for producing clinical signs and symptoms in only certain individuals, EBV has provided a model for many other candidate oncogenic viruses, including papilloma viruses, herpes simplex, and HTLV/LAV. In 1975, an international workshop was sponsored by the National Cancer Institute to address the problem of EBV production, thus facilitating basic research on the virus. This proved to be the last international meeting on EBV for almost a decade. In the past, progress in both clinical and basic research on EBV has been presented in two types of international meetings, the international herpesvirus workshops devoted primarily to basic research on both human and animal herpesviruses, and the international symposia on NPC, in which EBV-related studies were interspersed with clinical, epidemiologic and other etiologic aspects of this important human neoplasm.
Download or read book Epstein Barr Virus Volume 1 written by Christian Münz and published by Springer. This book was released on 2015-09-30 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epstein Barr virus (EBV) was discovered as the first human tumor virus around 50 years ago. Since its discovery in Burkitt’s lymphoma it has been associated with various other malignancies, infectious mononucleosis and even autoimmune diseases. The two book volumes on EBV summarize the first 50 years of research on this tumor virus, starting with historical perspectives on discovery, oncogenicity and immune control, reviewing the role that the virus plays in the various associated diseases and concluding with a discussion on how the immune system keeps persistent EBV infection under control in healthy EBV carriers and can be used to treat EBV associated diseases. The respective 32 chapters are written by international experts from three continents for health care providers, biomedical researchers and patients that are affected by EBV. The assembled knowledge should help to understand EBV associated diseases better and to develop EBV specific vaccination in the near future.
