Download or read book Neurotransmitter Receptor Binding written by Henry I. Yamamura and published by . This book was released on 1985 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neurotransmitter Release written by Hugo J. Bellen and published by Oxford University Press, USA. This book was released on 1999 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with background information on neurotransmitter release. Emphasis is placed on the rationale by which proteins are assigned specific functions rather than just providing facts about function.
Download or read book Neurotransmitter Receptors written by Sam J. Enna and published by Springer Science & Business Media. This book was released on 2013-12-11 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery that neuronal transmission can be chemically mediated, a large number of compounds have been found in the mammalian central nervous system which appear to function as neurotransmitter agents. Recently, electrophysiological and biochemical methods have been developed which have enabled neuroscientists to classify better the myriad of neurotransmitter receptor sites in brain and to study their properties in finer detail. As a result of these investigations, a significant number of new discoveries have been made about the mechanisms involved in neurotransmitter receptor interactions, the role neurotransmitters play in the actions of pharmacological agents and in the pathogenesis of various neuropsychiatric disorders. The present two volume text was compiled to summarize the information relating to the physiological, biochemical, pharmacological and functional characteristics of neurotransmitter receptor sites. While emphasis is placed on neurotransmitter receptors in the mammalian central nervous system, the characteristics of these receptors in other species, both vertebrate and invertebrate, are also discussed where appropriate. While these books cover the major classes of putative neurotransmitters - amino acids, peptides and biogenic amines - and are therefore broad in scope, each is discussed in a concise fashion to highlight the major points of historical and contemporary interest. In addition to outlining data, each chapter addresses current theories relating to the various aspects of receptor properties and function in an attempt to reveal the directions of future research and as a stimulus for other workers in the field.
Download or read book Neurotransmitter Receptors written by S. J. Enna and published by . This book was released on 1980 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neurotransmitter Receptors written by Sam J. Enna and published by Springer Science & Business Media. This book was released on 2013-12-12 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery that neuronal transmission can be chemically mediated, a large number of compounds have been found in the mammalian central nervous system which appear to function as neurotransmitter agents. Recently, electro physiological and biochemical methods have been developed which have enabled neuroscientists to classify better the myriad of neurotransmitter receptor sites in brain and to study their properties in finer detail. As a result of these investigations, a significant number of new discoveries have been made about the mechanisms involved in neurotransmitter receptor interactions, the role neurotransmitters play in the actions of pharmacological agents and in the pathogenesis of various neuropsychiatric disorders. The present two volume text was compiled to summarize the information relating to the physiological, biochemical, pharmacological and functional characteristics of neurotransmitter receptor sites. While emphasis is placed on neurotransmitter receptors in the mammalian central nervous system, the characteristics of these receptors in other species, both vertebrate and invertebrate, are also discussed where appropriate. While these books cover the major classes of putative neurotransmitters - amino acids, peptides and biogenic amines - and are therefore broad in scope, each is discussed in a concise fashion to highlight the major points of historical and contemporary interest. In addition to outlining data, each chapter addresses current theories relating to the various aspects of receptor properties and function in an attempt to reveal the directions of future research and as a stimulus for other workers in the field.
Download or read book Glutamate Related Biomarkers in Drug Development for Disorders of the Nervous System written by Institute of Medicine and published by National Academies Press. This book was released on 2011-08-05 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glutamate is the most pervasive neurotransmitter in the central nervous system (CNS). Despite this fact, no validated biological markers, or biomarkers, currently exist for measuring glutamate pathology in CNS disorders or injuries. Glutamate dysfunction has been associated with an extensive range of nervous system diseases and disorders. Problems with how the neurotransmitter glutamate functions in the brain have been linked to a wide variety of disorders, including schizophrenia, Alzheimer's, substance abuse, and traumatic brain injury. These conditions are widespread, affecting a large portion of the United States population, and remain difficult to treat. Efforts to understand, treat, and prevent glutamate-related disorders can be aided by the identification of valid biomarkers. The Institute of Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop on June 21-22, 2010, to explore ways to accelerate the development, validation, and implementation of such biomarkers. Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System: Workshop Summary investigates promising current and emerging technologies, and outlines strategies to procure resources and tools to advance drug development for associated nervous system disorders. Moreover, this report highlights presentations by expert panelists, and the open panel discussions that occurred during the workshop.
Download or read book Medical Biochemistry written by Antonio Blanco and published by Academic Press. This book was released on 2022-03-23 with total page 910 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of Medical Biochemistry is supported by more than 45 years of teaching experience, providing coverage of basic biochemical topics, including the structural, physical, and chemical properties of water, carbohydrates, lipids, proteins, and nucleic acids. In addition, the general aspects of thermodynamics, enzymes, bioenergetics, and metabolism are presented in straightforward and easy-to-comprehend language. This book ties these concepts into more complex aspects of biochemistry using a systems approach, dedicating chapters to the integral study of biological phenomena, including cell membrane structure and function, gene expression and regulation, protein synthesis and post-translational modifications, metabolism in specific organs and tissues, autophagy, cell receptors, signal transduction pathways, biochemical bases of endocrinology, immunity, vitamins and minerals, and hemostasis. The field of biochemistry is continuing to grow at a fast pace. This edition has been revised and expanded with all-new sections on the cell plasma membrane, the human microbiome, autophagy, noncoding, small and long RNAs, epigenetics, genetic diseases, virology and vaccines, cell signaling, and different modes of programmed cell death. The book has also been updated with full-color figures, new tables, chapter summaries, and further medical examples to improve learning and better illustrate the concepts described and their clinical significance. Integrates basic biochemistry principles with molecular biology and molecular physiology Illustrates basic biochemical concepts through medical and physiological examples Utilizes a systems approach to understanding biological phenomena Fully updated for recent studies and expanded to include clinically relevant examples and succinct chapter summaries
Download or read book Neurotransmitter Receptors written by Shozo Kito and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This meeting was held commemorating Dr. Kito's 10th Anniversary as Professor of the Third Department of Internal Medicine, Hiroshima University School of Medicine. Dr. Kito was born in 1927 in Nagoya, graduated from Tokyo University School of Medicine and received his M. D. in 1951. He spent his first academic years as a research associate (1952 - 1968) at the Third Department of Internal Medi cine, Tokyo University School of Medicine. During this period he studied for one year (1952 - 1953) at Illinois University School of Medicine, and acquired his Ph. D. in 1959. In 1968 he became Instructor and in 1971 he was appointed as Assistant Professor of Tokyo Women's Medical College. In 1973, he became Professor of the Third Department of Internal Medicine, Hiroshima University School of Medicine. Dr. Kito is a clinician but he is always enthusiastic about basic medicine. His major research field concerns neurotrans mitters and their receptors in the central nervous system. He prefers a combination of neurotransmitter immunohistochemistry and receptor autoradiography as research techniques. He is also engaged in biochemical studies on amyloid proteins. When the Eighth Inter national Congress of Pharmacology was held in Tokyo in 1981, Dr. Segawa, Dr. Yamamura, and Dr. Kuriyama organized a Satellite Symposium on Neurotransmitter Receptors in Hiroshima. Dr. Kito attended this meeting and was deeply impressed by the active presentations and discussions. In order to make some contribution to the progress of neuro sciences, Dr.
Download or read book Neuroreceptors and Signal Transduction written by S. Kito and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first Hiroshima Symposium of Neurotransmitter Receptors in 1983, there have been conspicuous advances in this field. For instance, our knowledge on transmembrane signalling mechanism has increased almost exponentially and this great stride has been linking areas of biology that had been previously considered of as being separate. The Second Hiroshima International Neurotransmitter Receptor Symposium was held on October 6 to 9 bringing together an outstanding group of neuroscientists from various disciplines to integrate these advances in the hope that their valuable contributions will make this meeting a tradition in this city. The original title of the Symposium was "Receptor Mechanism of Neurotransmitter and Neuropeptides". This volume is based on papers presented at this Second Hiroshima Symposium. Our aim editing this book is to discuss various neurotransmitter receptors in terms of their structural and biochemical properties, functions, ligands and related intracellular control mechanism, and to know the general denominators of all receptors. The editors believe that this book will provide a useful state-of-the-art summary of neuroreceptor fields at present and profit for those who could not participate in the Hiroshima Conference vicariously by reading the texts included in this volume. The editors acknowledge the help of many friends and colleagues in making this book possible. We are especially grateful to Dr. Shinobu Inagaki, former assistant professor of Third De-partment of Internal Medicine, Hiroshima University School of Medicine who made the Symposium successful as secretary-general through her devoted efforts. In 1988, Dr.
Download or read book Receptors in the Developing Nervous System written by Ian S. Zagon and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Receptors for cell hormones, growth factors, Fourth, alterations in the development of neu and neurotransmitters are involved in the ral receptors may have profound implications control and modulation of an enormous array for the structure and function of the of biological processes. The development of organism. As much as possible, the reper these receptors has distinct spatial and tem cussions of disrupting the orchestration of poral arrangements, and alterations in this receptor development in the nervous system pattern during embryogenesis can have signi are discussed. In many instances, however, ficant consequences for the well-being of the we are just beginning to learn about some fetus, infant, child and adult. The developing receptors and the authors may not be in a nervous system is particularly dependent on position to discuss the consequences of recep receptors because its period of structural and tor dysfunction. functional organization extends through both In designing these two volumes, we have prenatal and postnatal phases. Moreover, asked major figures in each field to review the receptors are a key element in neural com literature, to apprise the audience of their munication in both the developing and adult latest findings, and to provide a perspective on organism, so that the ontogeny of receptors is the role of receptors in the developing nervous crucial in determining the myriad connections system. These books are intended to sum forming the circuitry of the nervous system.
Download or read book Basic Neurochemistry written by R. Wayne Albers and published by Academic Press. This book was released on 2011-11-02 with total page 1121 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Neurochemistry, Eighth Edition, is the updated version of the outstanding and comprehensive classic text on neurochemistry. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from intracellular trafficking, stem cells, adult neurogenesis, regeneration, and lipid messengers. It contains expanded coverage of all major neurodegenerative and psychiatric disorders, including the neurochemistry of addiction, pain, and hearing and balance; the neurobiology of learning and memory; sleep; myelin structure, development, and disease; autism; and neuroimmunology. Completely updated text with new authors and material, and many entirely new chapters Over 400 fully revised figures in splendid color 61 chapters covering the range of cellular, molecular and medical neuroscience Translational science boxes emphasizing the connections between basic and clinical neuroscience Companion website at http://elsevierdirect.com/companions/9780123749475
Download or read book The Role of the Nucleus of the Solitary Tract in Gustatory Processing written by Robert M. Bradley and published by CRC Press. This book was released on 2006-10-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing an essential brainstem relay for three cranial nerves, the NST coordinates highly complex sensory information. While other functions of the NST have received attention, its role in gustatory processing has received little. The first reference devoted exclusively to gustatory processing, The Role of the Nucleus of the Solitary Tract in Gustatory Processing offers an in-depth review of one of the most important central relay stations in the brain. Combining widely dispersed research into a comprehensive single volume, it presents a thorough historical background, documents the anatomy of the rostral nucleus of the solitary tract (rNST), and explores the properties of synaptic transmitters and neurons within that tract. The book examines the role of reflex activities and considers factors that influence how gustatory rNST neurons respond to taste stimuli. It describes the development and maturational changes the rNST undergoes and considers the challenge involved with identifying rNST neural circuits. The Role of the Nucleus of the Solitary Tract in Gustatory Processing brings together expert investigators who have contributed substantially to the current knowledge of the anatomy, physiology, and developmental biology of the solitary nucleus. This pertinent work serves as a standard reference for those involved in the field, providing ready access to past investigations and inviting practitioners to create new approaches that will advance knowledge about the central processing of gustatory information.
Download or read book Handbook of Developmental Neurotoxicology written by William Slikker, Jr. and published by Academic Press. This book was released on 2018-01-04 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Developmental Neurotoxicology, Second Edition, provides a comprehensive view of the fundamental aspects of neurodevelopment, the pathways and agents that affect them, relevant clinical syndromes, and risk assessment procedures for developmental neurotoxicants. The editors and chapter authors are internationally recognized experts whose collaboration heralds a remarkable advance in the field, bridging developmental neuroscience with the principles of neurotoxicology. The book features eight new chapters with newly recruited authors, making it an essential text for students and professionals in toxicology, neurotoxicology, developmental biology, pharmacology, and neuroscience. Presents a comprehensive, up-to-date resource on developmental neurotoxicology with updated chapters from the first edition Contains new chapters that focus on subjects recent to the field Includes well-illustrated material, with diagrams, charts, and tables Contains compelling case studies and chapters written by world experts
Download or read book Serotonin Receptors in Neurobiology written by Amitabha Chattopadhyay and published by CRC Press. This book was released on 2007-05-17 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: A number of developments spanning a multitude of techniques makes this an exciting time for research in serotonin receptors. A comprehensive review of the subject from a multidisciplinary perspective, Serotonin Receptors in Neurobiology is among the first books to include information on serotonin receptor knockout studies. With contributions from l
Download or read book Neurotransmitter receptor Interactions written by D. J. Triggle and published by . This book was released on 1971 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Receptor Binding written by Alan A. Boulton and published by Humana. This book was released on 1986-06-20 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Techniques in the neurosciences are evolving rapidly. There are currently very few volumes dedicated to the methodology - ployed by neuroscrentists, and those that are available often seem either out of date or limited in scope. This series is about the methods most widely used by modern-day neuroscientists and 1s written by their colleagues who are practicing experts. Volume 1 will be useful to all neuroscientists since it concerns those procedures used routinely across the widest range of s- drsciplines. Collecting these general techniques together in a single volume stnkes us not only as a service, but will no doubt prove of exceptional utilitarian value as well. Volumes 2 and 3 describe all current procedures for the analyses of ammes and theirmetabolites and of amino acrds, respectively. These collections will clearly be of value to all neuroscientists working in or contemplating research in these fields. Similar reasons exist for Volume 4 on receptor binding techniques since experimental details are provided for many types of ligand-receptor binding, including chapters on general prin- ples, drug discovery and development, and a most useful app- dix on computer programs for Scatchard, nonlinear, and compe- tive displacement analyses. Volume 5 provides procedures for the assessment of enzymes involved in biogenic amine synthesis and catabolism. Volumes in the NEUROMETHODS series will be useful to neurochemists, -pharmacologists, -physrologists, -anatomists, psychopharmacologists, psychiatrists, neurologists, and chemists (organic, analytical, pharmaceutical, medicinal); in fact, everyone involved in the neurosciences, both basic and clinical.
Download or read book Spinal Afferent Processing written by T.L. Yaskh and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some 29 scientists from the fields of neuroanatomy, neurochemistry, neu rophysiology, neuropharmacology, and behavior have contributed their ef forts to this testimonial on behalf of the contributions made by Dr. F. W. L. Kerr to science and to those with whom he interacted. The intention of the contributors to this volume was to deal with the manifold advances that pertain to the substrates in spinal cord relating to the processing of sensory infor mation, a subject that in one form or another provoked time and again Kerr's native enthusiasm for research. The organization of the book follows a natural course from the peripheral innervation of the somatic and visceral organs (Winkelmann, Chapter 2) to the effective stimuli that activate these fibers and give rise to sensation under normal and pathological conditions (Campbell and Meyer, Chapter 3; Dubner and colleagues, Chapter 13; Dyck, Chapter 14) to the course these afferent systems take to enter the spinal cord (Coggeshall, Chapter 4) and to the organization of the systems through which this afferent information reaches the brain (Willis, Chapter 11; Vierck and colleagues, Chapter 12).
