Download or read book Neuropharmacology of Ethanol written by KOOB and published by Springer Science & Business Media. This book was released on 2013-04-18 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Neuropharmacology of Alcohol written by Kathleen A. Grant and published by Springer. This book was released on 2019-03-27 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume gives an overview of new insights to alcohol pharmacology using DREADDs (Designer Receptors and Unraveling the Neuropharmacology of Alcohol). It examines which pharmacological principles should be applied to understanding DREADDs taking into account some very current research. Additionally, this book covers important topics under the heading of “experimental pharmacology” and alcohol.
Download or read book Neuropharmacology of Ethanol written by Koob and published by . This book was released on 2014-01-15 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Pharmacology of Alcohol and Alcohol Dependence written by Henri Begleiter and published by Oxford University Press, USA. This book was released on 1996 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive review of the pharmacological effects of alcohol and the mechanisms underlying the pathogenesis of alcoholism. The book draws on general pharmacology, neuropharmacology, and alcohol studies to explore its theme. The second volume in the ALCOHOL AND ALCOHOLISM series, it focuses on the pharmacologic mechanisms underlying the development of alcoholism. The first section on basic pharmacology is concerned with those aspects that are common to all of alcohol's effects. These include pharmacokinetics, general metabolism, and cross-tolerance. The second section on neuropharmacology describes the effects of alcohol on various brain functions, including circulation and metabolism. The third section provides an in-depth review of the neurobiology of physical dependence, withdrawal, and physiological tolerance. The book as a whole gives a comprehensive and authoritative picture of the complex pharmacologic actions of alcohol, particularly on the nervous system. For clinicians and researchers in the field of alcohol and alcoholism, it will serve as a fundamental reference.
Download or read book Biochemical Pharmacology of Ethanol written by Edward Majchrowicz and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: A number of excellent symposia, reviews and monographs on the biology of ethanol have been published during the last decade. Al though it may appear that another such publication may be superflu ous, the subject of alcohol abuse is still open for further explora tion and the field of the biochemical pharmacology of ethanol is in its infancy. This is evidenced, for example, by the unavailability of any drugs that are designed specifically for the treatment of alcohol intoxication or alcohol addiction. The impetus for this publication was generated by a spontane ous enthusiasm following the symposium on BiochemicaZ Ph~acoZogy of EthanoZ that was organized at the annual meeting of the American Chemical Society, Division of Biological Chemistry in August 1973 in Chicago. It was the first symposium on such a topic ever in cluded in the program of that large society of American chemists. The original aim of the symposium was to acquaint the members of the society with some basic facts about the biological chemistry of ethanol. The symposium included seven papers and covered a rela tively narrow range of ethanol biochemistry. In view of the enthu siasm shown at the Chemical Society meeting, the panelists decided to publish the program and to amplify it by inclusion of additional topics which have remained relatively unexplored in earlier publica tions. In addition, reviews have been included which discuss old topics from a new perspective.
Download or read book Pharmacological Effects of Ethanol on the Nervous System written by Richard A. Deitrich and published by CRC Press. This book was released on 1995-12-21 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book dissects the effects of ethanol on the major neurotransmitter systems affected by ethanol and correlates these actions with the behavioral consequences. The subject is approached first from the perspective of the neurochemical system and the behaviors resulting from ethanol's effects on that system. The behaviors themselves are discussed in later chapters. Some older theories of the effects of ethanol such as the membrane fluidization hypothesis are evaluated in light of new and updated information. Fetal Alcohol Syndrome (FAS) as well as the structural damage in the brain by long term ethanol exposure are also discussed.
Download or read book The Neuropharmacology of Ethanol Dependence written by Stefanie Rassnick and published by . This book was released on 1993 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Alcohol and Neurobiology written by Ronald Ross Watson and published by CRC Press. This book was released on 1992-06-24 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Public attention and research efforts are being driven by an ever- increasing understanding of the problems and magnitude of alcohol abuse, particularly its neurological consequences. Two out of three high school students report that they used alcohol during the previous month. This continuing source of potential abusers, plus 10 million alcohol-abusing adults, along with the several million abusers of other drugs, costs the people of the U.S. more than $200 billion in lost wages, health care, theft, and shortened life span. An intimate, detailed knowledge of the effects of alcohol on the biochemical reactions and neurological changes is critical in preventing or treating abuse. We must study the mechanisms of ethanol's effects on the neurological system at a cellular and systematic level to understand its actions. These include modifications of hormonal regulation and production with major functional consequences. The progress of research over the past decade is encouraging as we begin to summarize and evaluate in detail advances in understanding changes in the biochemistry and physiology caused by ethanol. This information will assist the researcher, clinician, and student in comprehending the complex changes caused by direct and indirect effects of single drugs at the cellular level.
Download or read book The Pharmacology of Alcohol Abuse written by Henry R. Kranzler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: The subject of the book is the pharmacology of ethanol. It brings together the work of both basic and clinical investigators in the pharmacology of alcohol and alcohol abuse. The major focus is on the integration of findings from different levels of analysis, together with a discussion of recent insights from molecular biology in terms of their relevance for understanding ethanol's effects and the implications for the development of medications. Comprehensive in its scope, this book provides an up-to-date, in-depth treatment of the field, with particular emphasis on the integration of research findings from diverse approaches and how these findings might influence future investigations.
Download or read book Biochemistry and Pharmacology of Ethanol written by Edward Majchrowicz and published by . This book was released on 1979 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ethanol Its Active Metabolites and Their Mechanisms of Action Neurophysiological and Behavioral Effects written by Elio Acquas and published by Frontiers Media SA. This book was released on 2018-07-12 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ethanol, the main psychopharmacologically active ingredient of alcoholic drinks, represents a paradigmatic example of a research subject intrinsically able to perpetually self-generate interdisciplinary cutting-edge investigations. This eBook was inspired by the aim of providing an up-to-date characterization of the diverse effects of ethanol, of the possible mechanisms of action on different intracellular systems as well as of the hypothesized actions of ethanol and/or its metabolites on various neurotransmitters and neuromodulators. Indeed, the eBook provides a factual example of an excellent synthesis on the complex relationship between ethanol and its main biologically active metabolites (Chapter 1), on the behavioral and molecular consequences of early exposure to them (Chapter 2), on the recent proposals, advanced by the preclinical research, for new therapeutic approaches to distinct aspects of alcoholism (Chapter 3) and on the most recent and original preclinical evidence of the interactions between ethanol and/or its metabolites and the dopaminergic, adenosinergic and endocannabinoidergic systems (Chapter 4). Overall we believe that this eBook accomplishes its main goals of widening the perspective on this research subject and offering the readership a newer and, simultaneously, up-to-date and comprehensive scenery on ethanol’s and ethanol's active metabolites neurophysiological and behavioral effects.
Download or read book Biochemistry and Pharmacology of Ethanol written by Edward Majchrowicz and published by Springer. This book was released on 1979-09-01 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol abuse and alcoholism represents one of the major health, social, and economic issues facing not only America but much of the world. Problems with alcohol appear to be a common curse, afflicting almost all industrialized nations as well as the developing countries. at least 10 million people suffer the misuse. It is In the United States today of estimated that 205,000 individuals die prematurely each year from a variety ethanol-induced factors, including cirrhosis, cancer, heart disease, suicide, homi cide, and highway fatalities and other accidents. In purely economic terms, the alcohol-related cost to our society in 1975 is estimated at nearly $43 billion in lost production, medical expenses, motor vehicle accidents, fire losses, and the maintenance of social mechanisms to deal with these problems. But the economic impact pales in comparision with the psychological pain and anguish brought to alcoholics and their family and friends. The disease of alcoholism bears a close relation to the topic of our dedication, for it is equally insidious and sadistic, it destroys humanity and rational thought, and it brings terror, pain, and death.
Download or read book Biochemistry and Pharmacology of Ethanol written by Edward Majchrowicz and published by Springer. This book was released on 2012-03-19 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol abuse and alcoholism represents one of the major health, social, and economic issues facing not only America but much of the world. Problems with alcohol appear to be a common curse, afflicting almost all industrialized nations as well as the developing countries. at least 10 million people suffer the misuse. It is In the United States today of estimated that 205,000 individuals die prematurely each year from a variety ethanol-induced factors, including cirrhosis, cancer, heart disease, suicide, homi cide, and highway fatalities and other accidents. In purely economic terms, the alcohol-related cost to our society in 1975 is estimated at nearly $43 billion in lost production, medical expenses, motor vehicle accidents, fire losses, and the maintenance of social mechanisms to deal with these problems. But the economic impact pales in comparision with the psychological pain and anguish brought to alcoholics and their family and friends. The disease of alcoholism bears a close relation to the topic of our dedication, for it is equally insidious and sadistic, it destroys humanity and rational thought, and it brings terror, pain, and death.
Download or read book The Pharmacology of Alcohol Abuse written by Henry R Kranzler and published by . This book was released on 1994-12-23 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Alcohol and Opiates written by Kenneth Blum and published by Elsevier. This book was released on 2012-12-02 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol and Opiates: Neurochemical and Behavioral Mechanisms contains the proceedings of the 1976 conference, ""The Neurochemical and Behavioral Mechanisms of Alcohol and Opiate Dependence"", held in New York. The papers focus on the commonalities and distinctions of alcohol and opiates in terms of neurochemical and behavioral mechanisms. It also highlights key research findings on alcohol and drug dependence as well as advances in the understanding of opiate neurochemistry and the nature of alcoholism. Organized into two sections comprised of 22 chapters, this compilation begins with an overview of the various techniques used to produce and to measure alcohol dependence using animal models. It then discusses the neurochemical components of ethanol dependence, the pharmacogenetics of alcoholism, and the effects of alcohol on behavioral performance. The remaining chapters examine the pharmacology of isoquinoline alkaloids and ethanol interactions, the neurochemical aspects of opiate dependence, the pharmocological heterogeneity of narcotic receptors, and the pharmacology of endogenous opiate-like peptides. The book also introduces the reinforcement of behavior by morphine injections and the metabolic stereospecificity of opiate agonist and antagonist drugs. It concludes with an assessment of future research directions concerning opioid peptides (endorphins). This book is a valuable source of information for those seeking to build clinical programs designed to alleviate the sociological and medical ills associated with alcohol and opiate abuse and drug dependency.
Download or read book Biology of the NMDA Receptor written by Antonius M. VanDongen and published by CRC Press. This book was released on 2008-10-29 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written
Download or read book Alcohol and Neurobiology written by Ronald R. Watson and published by CRC Press. This book was released on 1992-06-24 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: The neurological consequences of alcohol abuse need additional research concentrating on prevention and treatment. Public attention and research efforts are being driven by an ever- increasing understanding of the problems and magnitude of alcohol on neurological development. The 10 million alcohol-abusing adults, along with unborn children exposed to alcohol in utero, cost the people of the U.S. more than $100 billion in lost wages, health care, theft, damaged mental functions, and shortened life span. An intimate, detailed knowledge of the effects of alcohol on the biochemical reactions and neurological changes is critical in preventing or treating abuse. We must study the mechanisms of ethanol's effects on the neurological system at a cellular and systematic level to understand its action. These include modifications of hormonal regulation and production with its major functional consequences. Brain development including its cells are a major focus and emphasis of this volume. The progress of research over the past decade is encouraging as we begin to summarize and evaluate in detail advances in understanding changes in the brain's biochemistry and physiology caused by ethanol. This information will assist the researcher, clinician, and student in comprehending the complex changes caused by direct and indirect effects of single drugs at the cellular level.
