Download or read book Neuropeptides and Their Peptidases written by Anthony John Turner and published by . This book was released on 1987 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Peptidases and Neuropeptide Processing written by and published by Academic Press. This book was released on 1995-02-08 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volumes in this series include contemporary techniques significant to a particular branch of neuroscience. They are an invaluable aid to the student as well as the experienced researcher not only in developing protocols in neuroscience but in disciplines where research is becoming closely related to neuroscience. Each volume of Methods in Neurosciences contains an index, and each chapter includes references. Dr. Conn became Editor-in-Chief of the series beginning with Volume 15, so each subsequent volume could be guest-edited by an expert in that specific field. This further strengthens the depth of coverage in Methods in Neurosciences for students and researchers alike. Comprehensive protocols included for: Enzymes involved in the activation of bioactive peptidases and proteins Prohormone/neuropeptide processing pathways Enzymes involved in peptide metabolism Posttranslational processing enzymes
Download or read book Neuropeptides and Other Bioactive Peptides written by Lloyd D. Fricker and published by Morgan & Claypool Publishers. This book was released on 2012 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuropeptides and peptide hormones represent the largest class of chemical messengers that transmit information from one cell to another. In this review, several decades of research on peptides in cell-cell signaling are summarized, with a focus on neuropeptide discovery, biosynthesis, and function. In addition to covering the well-studied aspects of neuropeptides, emerging concepts are discussed, including classical versus non-classical neuropeptides and direct versus indirect neuropeptides. Other potential functions for peptides in intercellular and intracellular signaling are also discussed. Table of Contents: Overview of Neuropeptides / Neuropeptide Discovery / Neuropeptide Biosynthesis / Neuropeptides After Secretion: Receptors and Peptidases / Representative Neuropeptides / Concluding Remarks and Future Directions / References / Author Biography
Download or read book Metabolism of Brain Peptides written by Gerard O'Cuinn and published by CRC Press. This book was released on 1995-06-09 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolism of Brain Peptides discusses neuropeptide metabolism in light of recent research. It describes the processing mechanisms in the production of biologically active peptides. It details distribution of the variety of neuropeptides in the brain and comprehensively reviews the effects of these neuropeptides on behavioral and physiological functions. The book also examines termination mechanisms for the biological activities of neuropeptides in light of recent knowledge of their distribution, their receptors and their possible inactivation enzymes in various functional regions of the brain and at the blood-brain barrier.
Download or read book Neuropeptide Systems as Targets for Parasite and Pest Control written by Timothy G. Geary and published by Springer Science & Business Media. This book was released on 2011-01-13 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: The need to continually discover new agents for the control or treatment of invertebrate pests and pathogens is undeniable. Agriculture, both animal and plant, succeeds only to the extent that arthropod and helminth consumers, vectors and pathogens can be kept at bay. Humans and their companion animals are also plagued by invertebrate parasites. The deployment of chemical agents for these purposes inevitably elicits the selection of resistant populations of the targets of control, necessitating a regular introduction of new kinds of molecules. Experience in other areas of chemotherapy has shown that a thorough understanding of the biology of disease is an essential platform upon which to build a discovery program. Unfortunately, investment of research resources into understanding the basic physiology of invertebrates as a strategy to illuminate new molecular targets for pesticide and parasiticide discovery has been scarce, and the pace of introduction of new molecules for these indications has been slowed as a result. An exciting and so far unexploited area to explore in this regard is invertebrate neuropeptide physiology. This book was assembled to focus attention on this promising field by compiling a comprehensive review of recent research on neuropeptides in arthropods and helminths, with contributions from many of the leading laboratories working on these systems.
Download or read book Peptidomics written by Mikhail Soloviev and published by John Wiley & Sons. This book was released on 2007-12-21 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive guide to peptidomics- a hands-on lab reference The first truly comprehensive book about peptidomics for protein and peptide analysis, this reference provides a detailed description of the hows and whys of peptidomics and how the techniques have evolved. With chapters contributed by leading experts, it covers naturally occurring peptides, peptidomics methods and new developments, and the peptidomics approach to biomarker discovery. Explaining both the principles and the applications, Peptidomics: Methods and Applications: * Features examples of applications in diverse fields, including pharmaceutical science, toxicity biomarkers, and neuroscience * Details the successful peptidomic analyses of biological material ranging from plants to mammals * Describes a cross section of analytical techniques, including traditional methodologies, emerging trends, and new techniques for high throughput approaches An enlightening reference for experienced professionals, this book is sufficiently detailed to serve as a step-by-step guide for beginning researchers and an excellent resource for students taking biotechnology and proteomics courses. It is an invaluable reference for protein chemists and biochemists, professionals and researchers in drug and biopharmaceutical development, analytical and bioanalytical chemists, toxicologists, and others.
Download or read book Principles of Bone Biology written by John P. Bilezikian and published by Academic Press. This book was released on 2008-09-29 with total page 2074 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants...it is all in one source written by the experts in the field The essential resource for anyone involved in the study of bones and bone diseases Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics Readers can easily search and locate information quickly as it will be online with this new edition
Download or read book Retinal and Choroidal Angiogenesis written by John Penn and published by Springer Science & Business Media. This book was released on 2008-01-19 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive, in-depth review of our current understanding of the growth of blood vessels within the eye. Novel therapeutic strategies for the treatment of ocular angiogenesis are discussed, as are the unique challenges presented by delivery of drugs to the eye. The book emphasizes basic principles rather than specific experimental results, although recently acquired data is frequently cited to illustrate points of broader theoretical significance.
Download or read book Schizophrenia and Psychotic Spectrum Disorders written by S. Charles Schulz and published by Oxford University Press. This book was released on 2016-04-01 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Schizophrenia and Psychotic Spectrum Disorders aims to engage young caregivers in psychiatry, psychology, nursing and social work so that they will be able to become well informed about this significant--and at times confusing--illness. Because schizophrenia is considered to be one of the most complicated and severe psychiatric disorders, this book has the goal of summarizing key issues of the illness, such as its presentation, frequency and age of onset, and diagnostic characteristics. It also contains informative chapters about the pathophysiology of schizophrenia, ranging from brain development issues, genetics, and likely abnormalities in neurotransmitters. This book will give young professionals and those joining the field an excellent and accessible background to treatment. In this area, Schizophrenia and Psychotic Spectrum Disorders provides a comprehensive approach to diagnosis, treatment initiation, strategies for non-response, approaches of therapy, and importantly, ways to provide family therapy and support.
Download or read book Neurosciences From Molecule to Behavior a university textbook written by C. Giovanni Galizia and published by Springer Science & Business Media. This book was released on 2013-07-08 with total page 735 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurosciences – a comprehensive approach This textbook covers neuroscience from cellular and molecular mechanisms to behavior and cognitive processing. We also address evolution of the nervous system, computational neuroscience, the history of neuroscience as a discipline and neurophilosophy – to name but a few. The book provides the newest state-of-the-art knowledge about neuroscience from across the animal kingdom, with particular emphasis on model species commonly used in neuroscience labs across the world: mouse, zebra fish, fruit fly, honeybee, and nematode worm. We aim at university students of neuroscience, psychology, biological sciences, and medical sciences, but also computer scientists, philosophers, or anybody interested in understanding how brains work.
Download or read book Practical Pulmonary Pathology written by Kevin O. Leslie and published by W B Saunders Company. This book was released on 2011 with total page 828 pages. Available in PDF, EPUB and Kindle. Book excerpt: With an innovative approach, the new edition by Kevin O. Leslie, MD and Mark R. Wick, MD, provides comprehensive, practical guidance in the accurate identification and interpretation of neoplastic and non-neoplastic diseases of the lungs. Illustrated in full color throughout, this "one-stop" resource captures key morphologic patterns for a full range of common and rare conditions and assists in the interpretation of complex diagnostic puzzles.
Download or read book Basic and Applied Bone Biology written by David B. Burr and published by Academic Press. This book was released on 2013-06-11 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of skeletal biology from the molecular level to the organ level, including cellular control, interaction and response; adaptive responses to various external stimuli; the interaction of the skeletal system with other metabolic processes in the body; and the effect of various disease processes on the skeleton. The book also includes chapters that address how the skeleton can be evaluated through the use of various imaging technologies, biomechanical testing, histomorphometric analysis, and the use of genetically modified animal models. Presents an in-depth overview of skeletal biology from the molecular to the organ level Offers "refresher" level content for clinicians or researchers outside their areas of expertise Boasts editors and many chapter authors from Indiana and Purdue Universities, two of the broadest and deepest programs in skeletal biology in the US; other chapter authors include clinician scientists from pharmaceutical companies that apply the basics of bone biology
Download or read book Handbook of Neurochemistry and Molecular Neurobiology written by Abel Lajtha and published by Springer Science & Business Media. This book was released on 2007-03-26 with total page 721 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Trends in Regulatory Peptides written by Hubert Vaudry and published by Frontiers Media SA. This book was released on 2018-07-24 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regulatory peptides represent the most diverse and versatile family of messenger molecules. They are produced by all living organisms from bacteria to mammals. They are involved in a wide variety of biological functions. Biologically active peptides and their receptors thus constitute an unlimited source of inspiration for the development of innovative drugs and cosmetics. The present eBook is a unique collection of research articles and reviews that provide a representative examplification of the latest progress in regulatory peptide research.
Download or read book The Peptidergic Neuron written by B. Krisch and published by Birkhäuser. This book was released on 2012-12-06 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuropeptides rank among the phylogenetically oldest interneuronal signal substances. In the concept of neuro-secretion they were identified as neurohormones by which - via the blood - the brain regulates peripheral functions. It is now evident that the neuropeptides act as neurotransmitters/-modulators, as (neuro-)hormones, and paracrine or autocrine signal substances in diverse parts of the body. This book reviews, in several comprehensive articles written by distinguished specialists, the state of the art in the field of neuropeptides and peptidergic neurons. Special topics concern molecular aspects of processing, release and degradation of neuropeptides, receptors and signal transduction, comparative and behavioural aspects, and immunoregulatory effects of neuropeptides and their involvement on pathology of the central nervous system.
Download or read book Neuropeptides and Immunoregulation written by Berta Scharrer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an updated overview of a rapidly develo- ping and exciting area of investigation dealing with the ro- le of neuropeptides in immunoregulatory processes. Existing texts focus on the bidirectional exchange of signals among the nervous, endocrine and immune systems in mammals, car- ried out primarily by the enkephalin and proopiomelanocortin families of neuropeptides and lymphokines. This collection of material is the first one to include pertinent informa- tion obtained in invertebrates, which has considerably ad- vanced our knowledge of the role of opioid neuropeptides, especiallyin another activity of the immune system, that of autoregulation. The study and interpretation of the remark- able parallelisms between these phenomena observed in inver- tebrates and vertebrates bring new insight into the me- chanisms of neuroimmunobiological integration with both general biological and clinical implications.
Download or read book Peptide based Drug Discovery written by Ved Srivastava and published by Royal Society of Chemistry. This book was released on 2017-06-26 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: With potentially high specificity and low toxicity, biologicals offer promising alternatives to small-molecule drugs. Peptide therapeutics have again become the focus of innovative drug development efforts backed up by a resurgence of venture funds and small biotechnology companies. What does it take to develop a peptide-based medicine? What are the key challenges and how are they overcome? What are emerging therapeutics for peptide modalities? This book answers these questions with a holistic story from molecules to medicine, combining the themes of design, synthesis and clinical applications of peptide-based therapeutics and biomarkers. Chapters are written and edited by leaders in the field from industry and academia and they cover the pharmacokinetics of peptide therapeutics, attributes necessary for commercially successful metabolic peptides, medicinal chemistry strategies for the design of peptidase-resistant peptide analogues, disease classes for which peptide therapeutic are most relevant, and regulatory issues and guidelines. The critical themes covered provide essential background information on what it takes to develop peptide-based medicine from a chemistry perspective and views on the future of peptide drugs. This book will be a valuable resource not only as a reference book for the researcher engaged in academic and pharmaceutical setting, from basic research to manufacturing and from organic chemistry to biotechnology, but also a valuable resource to graduate students to understand discovery and development process for peptide-based medicine.
