Download or read book Neuropeptide Y in the Central Nervous System and Adrenal Gland written by M. E. de Quidt and published by . This book was released on 1985 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Neuropeptides and Brain Function written by and published by Elsevier. This book was released on 2011-09-22 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuropeptides and Brain Function

Download or read book Neuropeptide Y and Drug Development written by Lars Grundemar and published by Elsevier. This book was released on 1996-11-15 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuropeptide Y (NPY) is a ubiquitous and important messenger in the nervous system, with a wide range of physiological roles. It is involved in the body energy balance and is one of the most potent stimuli of food intake known. NPY also acts to regulate central and peripheral autonomic functions. This book, written by academic and industrial experts in the field, links the most recent basic experimental knowledge about NPY and its receptors with areas of clinical importance. This book will be of interest to those working in all areas of research affected by NPY, such as food intake and energy homeostasis, cardiovascular regulation and G-protein-coupled receptors, as well as those interested in the development of drugs as NPY targets. - The hypothalamic role of NPY and its relationship with eating disorders and diabetes - The sympathetic nervous system role of NPY and its involvement in cardiovascular disorders - Characterization of NPY receptor types and their brain distribution, molecular biology and pharmacology - Development of peptide and non-peptide receptor antagonists

Download or read book Brain Neuropeptide Y Mechanisms written by Anders Härfstrand and published by . This book was released on 1987 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Receptors for Neuropeptide Y NPY in the Rat and Human Central Nervous System written by Anders Undén and published by . This book was released on 1988 with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Neuropeptide Y and Related Peptides written by Martin C. Michel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: After a little more than 20 years since the original discovery of neuropeptide Y (NPY) by Tatemoto and colleagues, the field of NPY research has made remarkable progress and is coming of age.The present volume addresses all major topics in connection with NPY and related peptides by established leaders in their respective areas. Experienced NPY-aficionados will certainly find new and useful additional information in this volume and newcomers to the field will hopefully discover how much exciting research this still has to offer.

Download or read book Central and Peripheral Significance of Neuropeptide Y and Its Related Peptides written by Janet M. Allen and published by . This book was released on 1990 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Stress Neuropeptides and systemic disease written by James McCubbin and published by Academic Press. This book was released on 2012-12-02 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stress, Neuropeptides, and Systemic Disease traces the development of the neuropeptide hypothesis from its anatomical substrate to its functional correlates in animal and pre-clinical human models of stress-induced disease. The book contains articles that discuss the different aspects and findings on the study of neuropeptides such as the histochemical localization of peptide-containing cells and peptidergic receptors; the current concepts in hypothalamo-pituitary-adrenal axis regulation; neuropeptides involved in stress and their distribution in the mammalian central nervous system; and neuropeptide-mediated regulation of the neuroendocrine and autonomic responses to stress. The methods of measuring neuropeptides and their metabolism; stress responses and the pathogenesis of arthritis; brain peptides and gastrointestinal transit; and diminished opioid inhibition of blood pressure and pituitary function in hypertension development are presented as well. Physicians, neurobiologists, pharmacologists, and biological scientists will find the book very interesting.

Download or read book Modulatory Interactions of Neuropeptide Y NPY on Sympathetic Neurotransmission written by Pia Linton-Dahlöf and published by . This book was released on 1989 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Effect of Neuropeptide Y P30 on Neurons of the Central Nervous System written by Tim Wilfried Rattay and published by . This book was released on 2013 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Neuropeptide Y written by Viktor Mutt and published by . This book was released on 1989 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Neuropeptides in the Spinal Cord written by F. Nyberg and published by Elsevier. This book was released on 1995-10-30 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book devoted exclusively to examining the role of neuropeptides in the spinal cord. Great progress has been made recently in our understanding of the role of neuropeptides in neurotransmission. New tools have been developed to help study the function of endogenous neuropeptides in health and disease. Because the general organization of the spinal cord is well conserved among species and neuropeptides appear to have a major role in spinal neurotransmission, this book is a timely compendium of recent research in this field. The volume will help to stimulate further research in the field of neuropeptides which will lead to better understanding of this role in health and disease.

Download or read book Peptide Transport and Delivery into the Central Nervous System written by Laszlo Prokai and published by Birkhäuser. This book was released on 2012-12-06 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypo- or hypersecretion, alteration in storage, release, catabolism, and post-translational processing of neuropeptides are associated with the etiology of many diseases affecting the central nervous system (CNS). Various peptides native to the brain and the spinal cord, as well as various synthetic peptides, peptide analogues and peptidomimetics developed as their agonists or antagonists could be useful in the treatment of these CNS maladies. However, peptides face a formidable obstacle in reaching the intended site of action due to the existence of the blood-brain barrier (BBB), a vital element in the regulation of the internal environment of the brain and the spinal cord. After reviews on the role and neuropharmaceutical potential of peptides, properties of the BBB in the context of peptide transport in the CNS and potential transport mechanisms to cross the BBB, this volume discusses the development, present state-of-the-art and future trends of various strategies to overcome this major obstacle to peptide pharmacotherapy involving the CNS. Chapters are devoted to cover invasive approaches that circumvent the BBB by direct administration into the brain or the spinal cord and by transiently opening the tight junctions of or permeabilizing the endothelial cells separating the systemic circulation from the interstitial fluid of the CNS. Subsequently, physiologically based strategies that utilize biological carriers to gain access to the CNS are discussed in detail, followed by methods encompassing prodrug and chemical delivery/targeting strategies, which aim at altering the properties of the peptide to enhance BBB transport, and drug delivery strategies based on peptide vectors. Finally, a comparative evaluation on the present status and perspectives of the techniques is presented.

Download or read book The Effect of Neuropeptide Y P30 on Neuroms of the Central Nervous System written by Tim Wilfried Rattay and published by . This book was released on 2013 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Neuropeptides in Neuroprotection and Neuroregeneration written by Fred Nyberg and published by CRC Press. This book was released on 2012-06-19 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although the genomic era is no longer in its infancy, the life sciences are still facing questions about the role of endogenous proteins and peptides in homeostasis and pathologies. Delving into one of the most current fields of interest in biology and medicine, Neuropeptides in Neuroprotection and Neuroregeneration describes the impact of neuropeptides on neuroprotection and neuroregeneration. The book begins with chapters describing important features of the endogenous neuropeptide systems related to their formation, receptor signaling, and inactivation. It includes chapters focused on the design and development of peptide-like drugs (peptidomimetics). In addition, the book covers: General aspects regarding the biosynthesis, structures, and distribution of neuroactive peptides and their receptors Basic mechanisms for neuropeptide action, metabolism, as well as techniques for their detection and aspects essential for the cellular mechanisms underlying brain pathology Neuropeptides known for their impact in neurodegenerative and neuroprotective processes Fundamental aspects as well as recent progress in the development of peptidomimetics of neuroprotective and cognition-enhancing peptides

Download or read book Peptide and Amino Acid Transport Mechanisms in the Central Nervous System written by Ljubiša Rakić and published by Stockton Press. This book was released on 1988 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addresses the regulation, within the brain extracellular fluid, of peptide and amino acid levels, particularly neurotransmitters and neuromodulators. Particular attention is devoted to the way in which peptides may either penetrate the blood-brain barrier or alter its permeability to other solutes. Focuses on central nervous system disease, especially in designing drugs and agents which will penetrate the blood-brain barrier and expert central nervous actions. Annotation copyrighted by Book News, Inc., Portland, OR

Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.