Download or read book Neuropeptide GPCRs in neuroendocrinology written by Jae Young Seong and published by Frontiers E-books. This book was released on 2014-11-07 with total page 826 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human genome encompasses ˜ 860 G protein-coupled receptors (GPCRs) including 374 non-chemosensory GPCRs. Half of these latter GPCRs recognize (neuro)peptides as natural ligands. GPCRs thus play a pivotal role in neuroendocrine communication. In particular, GPCRs are involved in the neuroendocrine control of feeding behavior, reproduction, growth, hydromineral homeostasis and stress response. GPCRs are also major drug targets and hence possess a strong potential for the development of innovative pharmaceuticals. The aim of this Research Topic was to assemble a series of review articles and original research papers on neuropeptide GPCRs and their ligands that would illustrate the different facets of the studies currently conducted in this domain.
Download or read book Neuropeptide GPCRs in Neuroendocrinology Volume II written by Maria Lucia Narducci and published by Frontiers Media SA. This book was released on 2023-07-07 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Clinical Neuroendocrinology Neuropeptide Gpcrs written by Dylan Edwards and published by States Academic Press. This book was released on 2021-11-16 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: The branch of biology which focuses on the relationship between the endocrine and the nervous system is termed as neuroendocrinology. The regulation of the activity of the hormones by the brain is studied within this field. The physiological processes in the body are regulated by a process known as neuroendocrine integration, wherein the endocrine and nervous system function together. The major neuroendocrine systems in the body are Hypothalamic-pituitary-adrenal axis (HPA axis), Hypothalamic-pituitary-thyroid axis (HPT axis), Hypothalamic-pituitary-gonadal axis (HPG axis) and Hypothalamic-neurohypophyseal system. GPCRs are G protein-coupled receptors, which can bind to numerous neuropeptides. This book is a compilation of chapters that discuss the most vital concepts and emerging trends in the field of neuroendocrinology. It presents the complex subject of neuropeptide GPCRs in the most comprehensible and easy to understand language. The extensive content of this book provides the readers with a thorough understanding of the subject.
Download or read book Orphan G Protein Coupled Receptors and Novel Neuropeptides written by Olivier Civelli and published by Springer Science & Business Media. This book was released on 2008-05-15 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade it has been shown that orphan G protein-coupled receptors (GPCRs) can be used as targets to discover novel neuropeptides. A dozen neuropeptides have been identified through this approach. Each of these neuropeptides has opened new doors for our understanding of fundamental physiological or behavioral responses. For example the orexins, MCH and ghrelin carry fundamental roles in regulating food intake while neuropeptide S, neuromedin S, the prokineticins and the orexins are major players in modulating sleep and circadian rhythms. The chapters of this book review the latest research in the field, most of them are written by the original discoverers of the respective novel neuropeptide. Emphasis is set not only on their discovery but also on their functional significance. Since many of these neuropeptides are part of drug discovery programs, this book impacts academic as well as pharmaceutical research.
Download or read book Neuroendocrinology Recent Studies in Neuropeptide Gpcrs written by Dylan Edwards and published by . This book was released on 2022-09-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroendocrinology is the branch of physiology which deals with the study of interactions between the endocrine system and the nervous system. It encompasses the way brain regulates the hormonal activity in the body. To regulate the physiological processes of the human body, the endocrine and nervous systems often act together and the process is known as neuroendocrine integration. Neuroendocrine system is a system by which hypothalamus maintains homeostasis by regulating metabolism, energy utilization, eating and drinking behavior, reproduction, blood pressure and osmolarity. G protein-coupled receptors (GPCRs) are the neuropeptide targets via which the intracellular signaling transduction pathways are activated. This book is a valuable compilation of topics, ranging from the basic to the most complex advancements in the field of neuroendocrinology. It is an upcoming field of science that has undergone rapid development over the past few decades. This book is a resource guide for experts as well as students.
Download or read book Orphan G Protein Coupled Receptors and Novel Neuropeptides written by Olivier Civelli and published by Springer. This book was released on 2009-08-29 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade it has been shown that orphan G protein-coupled receptors (GPCRs) can be used as targets to discover novel neuropeptides. A dozen neuropeptides have been identified through this approach. Each of these neuropeptides has opened new doors for our understanding of fundamental physiological or behavioral responses. For example the orexins, MCH and ghrelin carry fundamental roles in regulating food intake while neuropeptide S, neuromedin S, the prokineticins and the orexins are major players in modulating sleep and circadian rhythms. The chapters of this book review the latest research in the field, most of them are written by the original discoverers of the respective novel neuropeptide. Emphasis is set not only on their discovery but also on their functional significance. Since many of these neuropeptides are part of drug discovery programs, this book impacts academic as well as pharmaceutical research.
Download or read book Molecular Neuroendocrinology written by David Murphy and published by John Wiley & Sons. This book was released on 2016-01-19 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Neuroendocrinology: From Genome to Physiology, provides researchers and students with a critical examination of the steps being taken to decipher genome complexity in the context of the expression, regulation and physiological functions of genes in neuroendocrine systems. The 19 chapters are divided into four sectors: A) describes and explores the genome, its evolution, expression and the mechanisms that contribute to protein, and hence biological, diversity. B) discusses the mechanisms that enhance peptide and protein diversity beyond what is encoded in the genome through post-translational modification. C) considers the molecular tools that today’s neuroendocrinologists can use to study the regulation and function of neuroendocrine genes within the context of the intact organism. D) presents a range of case studies that exemplify the state-of-the-art application of genomic technologies in physiological and behavioural experiments that seek to better understand complex biological processes. • Written by a team of internationally renowned researchers • Both print and enhanced e-book versions are available • Illustrated in full colour throughout This is the third volume in a new Series ‘Masterclass in Neuroendocrinology’ , a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology. Series Editors: John A. Russell, University of Edinburgh, UK and William E. Armstrong, The University of Tennessee, USA
Download or read book Molecular Neuroendocrinology written by David Murphy and published by John Wiley & Sons. This book was released on 2015-12-24 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Neuroendocrinology: From Genome to Physiology, provides researchers and students with a critical examination of the steps being taken to decipher genome complexity in the context of the expression, regulation and physiological functions of genes in neuroendocrine systems. The 19 chapters are divided into four sectors: A) describes and explores the genome, its evolution, expression and the mechanisms that contribute to protein, and hence biological, diversity. B) discusses the mechanisms that enhance peptide and protein diversity beyond what is encoded in the genome through post-translational modification. C) considers the molecular tools that today’s neuroendocrinologists can use to study the regulation and function of neuroendocrine genes within the context of the intact organism. D) presents a range of case studies that exemplify the state-of-the-art application of genomic technologies in physiological and behavioural experiments that seek to better understand complex biological processes. • Written by a team of internationally renowned researchers • Both print and enhanced e-book versions are available • Illustrated in full colour throughout This is the third volume in a new Series ‘Masterclass in Neuroendocrinology’ , a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology. Series Editors: John A. Russell, University of Edinburgh, UK and William E. Armstrong, The University of Tennessee, USA
Download or read book Role of Neuropeptide Receptors in Neuroendocrinology written by Gilbert Holmes and published by . This book was released on 2022-09-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroendocrinology is a branch of biology which is concerned with the functional and anatomical interactions between the endocrine system and the nervous system. Major neuroendocrine systems are hypothalamic-pituitary-adrenal axis, hypothalamic-pituitary-thyroid axis, hypothalamic-pituitary-gonadal axis and hypothalamic-neurohypophyseal system. Neuropeptide receptors are the G-protein coupled class that comprises of seven transmembrane receptors. Peptides are released into the synaptic cleft and they activate these receptors through high affinity binding and also mediate internal signaling events through cytoplasmic G-protein coupled effector. When these receptors are activated, this inhibits and activates a variety of second messenger systems which results in cell firing, phosphorylation and dephosphorylation events, modulation of membrane threshold and alteration of gene expression. This book covers in detail some existent theories about the role of neuropeptide receptors in neuroendocrinology. It presents researches and studies performed by experts across the globe. Students, researchers, experts and all associated with this field will benefit alike from this book.
Download or read book Clinical Neuroendocrinology written by Michael Wilkinson and published by Cambridge University Press. This book was released on 2019-01-03 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise and innovative account of clinical neuroendocrine disorders and the key principles underlying their diagnosis and management.
Download or read book Trends in Regulatory Peptides written by Hubert Vaudry and published by Frontiers Media SA. This book was released on 2018-07-24 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regulatory peptides represent the most diverse and versatile family of messenger molecules. They are produced by all living organisms from bacteria to mammals. They are involved in a wide variety of biological functions. Biologically active peptides and their receptors thus constitute an unlimited source of inspiration for the development of innovative drugs and cosmetics. The present eBook is a unique collection of research articles and reviews that provide a representative examplification of the latest progress in regulatory peptide research.
Download or read book Ligand written by Chandraleka Saravanan and published by BoD – Books on Demand. This book was released on 2018-05-23 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book Ligand describes the diversity and versatility of ligands, covering structural features, donor-acceptor properties and secondary functions like molecular recognition. Moreover, this book also provides a comprehensive account on the applicability like catalysis, sensors, supramolecular assembly, photochemical property, bioinorganic chemistry, and so on. The advancement of fundamentals in ligand design and the control of physicochemical properties of coordination compounds has largely increased emphasis on understanding the structural and electronic features toward different perspectives in materials science. In this regard, this book has a special appeal to chemists, biologists and others. This book will be beneficial for the graduate students, teachers, researchers and other professionals who are interested to fortify and expand their knowledge in chemistry, biology, microbiology, biotechnology, materials science, environmental science and so on.
Download or read book Advances in Invertebrate Neuro Endocrinology written by Saber Saleuddin and published by CRC Press. This book was released on 2020-02-14 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Invertebrate (Neuro)Endocrinology: A Collection of Reviews in the Post-Genomic Era (2-volume set) provides an informative series of reviews from expert scientists who are at the forefront of their research into the endocrinology of invertebrates. These two volumes are timely and appropriate in this post-genomic era because of the rapid pace of change brought about by genome projects, functional genomics, and genetics (omics technologies). The volume shows the rich history and strong tradition of cutting-edge research using invertebrates that has opened up our broader understanding of comparative endocrinology and the evolution of regulatory pathways and systems. These reviews set the scene and context for this exciting new era of understanding that has come from this post-genomic revolution. This book undertakes the daunting task of covering most of the diverse endocrine systems that exist among invertebrates. The papers in this book will advance our knowledge of invertebrate endocrinology but also of endocrinology in general, making the book will be valuable to researchers and students.
Download or read book Peptidomics written by Mikhail Soloviev and published by John Wiley & Sons. This book was released on 2007-12-21 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive guide to peptidomics- a hands-on lab reference The first truly comprehensive book about peptidomics for protein and peptide analysis, this reference provides a detailed description of the hows and whys of peptidomics and how the techniques have evolved. With chapters contributed by leading experts, it covers naturally occurring peptides, peptidomics methods and new developments, and the peptidomics approach to biomarker discovery. Explaining both the principles and the applications, Peptidomics: Methods and Applications: * Features examples of applications in diverse fields, including pharmaceutical science, toxicity biomarkers, and neuroscience * Details the successful peptidomic analyses of biological material ranging from plants to mammals * Describes a cross section of analytical techniques, including traditional methodologies, emerging trends, and new techniques for high throughput approaches An enlightening reference for experienced professionals, this book is sufficiently detailed to serve as a step-by-step guide for beginning researchers and an excellent resource for students taking biotechnology and proteomics courses. It is an invaluable reference for protein chemists and biochemists, professionals and researchers in drug and biopharmaceutical development, analytical and bioanalytical chemists, toxicologists, and others.
Download or read book Handbook of Neuroendocrinology written by George Fink and published by Academic Press. This book was released on 2012 with total page 895 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroendocrinology underpins fundamental physiological, molecular, biological, and genetic principles such as the regulation of gene transcription and translation. This handbook highlights the experimental and technical foundations of each area's major concepts and principles.
Download or read book Behavioral Genetics of the Fly Drosophila Melanogaster written by Josh Dubnau and published by Cambridge University Press. This book was released on 2014-06-26 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive portrayal of the behaviour genetics of the fruit fly (Drosophila melanogaster) and the methods used in these studies.
Download or read book Schizophrenia and Psychotic Spectrum Disorders written by S. Charles Schulz and published by Oxford University Press. This book was released on 2016-04-01 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Schizophrenia and Psychotic Spectrum Disorders aims to engage young caregivers in psychiatry, psychology, nursing and social work so that they will be able to become well informed about this significant--and at times confusing--illness. Because schizophrenia is considered to be one of the most complicated and severe psychiatric disorders, this book has the goal of summarizing key issues of the illness, such as its presentation, frequency and age of onset, and diagnostic characteristics. It also contains informative chapters about the pathophysiology of schizophrenia, ranging from brain development issues, genetics, and likely abnormalities in neurotransmitters. This book will give young professionals and those joining the field an excellent and accessible background to treatment. In this area, Schizophrenia and Psychotic Spectrum Disorders provides a comprehensive approach to diagnosis, treatment initiation, strategies for non-response, approaches of therapy, and importantly, ways to provide family therapy and support.
