Download or read book The Neurobiology of Aging and Alzheimer Disease in Down Syndrome written by Elizabeth Head and published by Academic Press. This book was released on 2021-08-31 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurobiology of Aging and Alzheimer Disease in Down Syndrome provides a multidisciplinary approach to the understanding of aging and Alzheimer disease in Down syndrome that is synergistic and focused on efforts to understand the neurobiology as it pertains to interventions that will slow or prevent disease. The book provides detailed knowledge of key molecular aspects of aging and neurodegeneration in Down Syndrome by bringing together different models of the diseases and highlighting multiple techniques. Additionally, it includes case studies and coverage of neuroimaging, neuropathological and biomarker changes associated with these cohorts. This is a must-have resource for researchers who work with or study aging and Alzheimer disease either in the general population or in people with Down syndrome, for academic and general physicians who interact with sporadic dementia patients and need more information about Down syndrome, and for new investigators to the aging and Alzheimer/Down syndrome arena. Discusses the complexities involved with aging and Alzheimer’s disease in Down syndrome Summarizes the neurobiology of aging that requires management in adults with DS and leads to healthier aging and better quality of life into old age Serves as learning tool to orient researchers to the key challenges and offers insights to help establish critical areas of need for further research
Download or read book Alzheimer s Disease written by Ralph W. Richter and published by Springer Science & Business Media. This book was released on 2003-10-10 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer’s disease (AD) is a devastating and dehumanizing illness affecting increasingly large numbers of elderly and even middle-aged persons in a worldwide epidemic. Alzheimer’s Disease: A Physician’s Guide to Practical Management was written by selected clinicians and scientists who represent some of the world’s leading centers of excellence in AD research. The editors are proud and grateful for their profound contributions. This book is particularly designed to assist physicians and other health-care professionals in the evaluation, assessment, and treatment of individuals with AD. At the same time, by illuminating the basic scientific background, we hope to provide state-of-the art information about the disease and possible future therapeutic strategies. The recent psychiatric treatment aspects of AD are also clearly presented. Because the early diagnosis of the dementia process is now considered of increasing importance, we focus particularly in several chapters on early changes and preclinical conditions, such as mild cognitive impairment and predementia AD.
Download or read book The Neuropathology of Dementia written by Margaret M. Esiri and published by Cambridge University Press. This book was released on 2004-07-22 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely rewritten and updated, this new edition is almost twice the size of its predecessor. Illustrated in colour throughout, and with contributions from the world's leading authorities, it is the definitive reference on the neuropathology of dementia. It gives practical guidance to pathologists, describes the contribution of neuroimaging to diagnosis, and surveys the clinical features of dementia. New material includes: Three entirely new chapters on neuroimaging, molecular diagnostics, and transgenic models. Two chapters on tauopathies under new authorship. A chapter under new authorship on synucleinopathies, which includes multiple system atrophy.
Download or read book Neuropathology of Aging and Alzheimer s Disease written by Rudy J. Castellani and published by Elsevier Health Sciences. This book was released on 2025-02 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuropathology of Aging and Alzheimer’s disease takes a foundational approach to the topic by offering basic scientific information and the latest advancements in the field. The focus of this reference is on neuropathology, given recent advances in tissue characterization in aging and in Alzheimer’s Disease. Neuropathology has direct relevance to therapeutic constructs and allows for an in-depth understanding of disease pathogenesis. It is a synthesis of the salient issues with respect to pathology, pathogenesis, diagnosis, disease, normal aging, biomarker relevance, and prospects for therapeutic intervention, based on a collective of many decades on the part of the authors confronting the challenges of both science and neuropathological diagnosis.
Download or read book Molecular Neuropathology of Aging written by Peter Davies and published by Cold Spring Harbor Laboratory Press. This book was released on 1987 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Sense and Senility The Neuropathology of the Aged Human Brain written by David M.A. Mann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: nly two things are certain in life, one is that all of us will inevita Obly grow older, the other is that at some point during or at the end of this process we shall die. Inherent to the passage of time is a deterio ration in the structural and functional integrity of our bodies, this pro gressing to such an extent that one or more organ systems will eventu ally begin to fail with the continued health and well-being of the individual coming under threat. Age-associated deficiencies in the musculo-skeletal, cardiovascular, or endocrine systems producing arthri tis, hypertension, stroke or diabetes are all too apparent in our elderly population yet internally caused failures in the function of the nervous system provide the common, and mostly intractable, problems of memory and intellect or locomotion that face and frustrate clinicians. Perhaps the most important factor which can decide the outcome of research studies professing to examine the effects of the passage of time (i. e. the 'process of aging') on the function of the nervous system, or indeed any other organ system, is the selection of appropriate or repre sentative subjects for investigation. The heart of this problem lies in defining what might be considered as 'normal' aging as distinct from age-associated disease; setting the 'goal posts of normality' continues to 1 be a matter of considerable debate.
Download or read book Senile Dementia of the Alzheimer Type written by Jörg Traber and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Society is showing increasing concern for disorders related to aging that lead to a loss of brain function. In view of the enormous proportion of elderly people in our society today, brain aging is more than ever subject to challenge to us all, not only politicians and health authorities, but every individual who is confronted with the difficult situation of watching the mental powers of apparently healthy elderly friends, neighbours, or relatives fail, often with alarming rapidity. This challenge is directed especially toward us scientists. As one of our colleagues succinctly put it 2 years ago at the close of our First International Symposium on Brain Aging: "Do something. We are not dealing here with just another disease; we are concerned with human dignity. " More than any statistics, these words convinced me that Tropon's decision to leave the field of classic CNS pharmacology and move into the field of gerontopsychopharmacology was the right one, even though we knew that success would be uncertain and that, even if it finally comes it will be many years hence. At this point, let me add a personal comment: each one of us is judged by his or her own success. We live in a competitive society where success counts. This applies not only to the businessman, but also to the scientist, in particular, to those in industry.
Download or read book Mild Cognitive Impairment written by Ronald C. Petersen and published by Oxford University Press. This book was released on 2003-01-09 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: What are the boundary zones between normal aging and Alzheimer's disease (AD)? Are many elderly people whom we regard as normal actually in the early stages of AD? Alzheimer's disease does not develop overnight; the early phases may last for years or even decades. Recently, clinical investigators have identified a transitional condition between normal aging and and very early Alzheimer's disease that they have called mild cognitive impairment, or MCI. This term typically refers to memory impairment beyond what one would expect in individuals of a given age whose other abilities to function in daily life are well preserved. Persons who meet the criteria for mild cognitive impairment have an increased risk of progressing to Alzheimer's disease in the near future. Though many questions about this condition and its underlying neuropathology remain open, full clinical trials are currently underway worldwide aimed at preventing the progression from MCI to Alzheimer's disease. This book addresses the spectrum of issues involved in mild cognitive impairment, and includes chapters on clinical studies, neuropsychology, neuroimaging, neuropathology, biological markers, diagnostic approaches, and treatment. It is intended for clinicians, researchers, and students interested in aging and cognition, among them neurologists, psychiatrists, geriatricians, clinical psychologists, and neuropsychologists.
Download or read book Clinical Neurology of Aging written by Martin L. Albert and published by Oxford University Press, USA. This book was released on 1994 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thorough revision of a well-established text presents essential information on the neurobiology of aging. There are new chapters on competency and ethics, problems of daily living, psychopharmacology, and stability and falls. Written in a accessible style, this book will be invaluable to clinicians and neurologists who treat elderly patients.
Download or read book Pathology of the Aging Human Nervous System written by Serge Duckett and published by Oxford University Press. This book was released on 2001-05-17 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a concise and practical compendium of neuropathological information for all professionals whose responsibility it is to make diagnoses, care, and help elderly humans afflicted with neurological and/or psychiatric disorders. The term neuropathology includes a multitude of disciplines including pathology, histology, genetics, immunology, biochemistry, radiology, etc. This disciplinary approach is reflected in this book. This new edition has been completely revised and brought up to date from the 20th to the 21st century. Basic neuroscientists were invited to contribute chapters explaining and describing basic scientific principles underlying the neuropathological disciplines. Also, additional information is provided concerning medic-legal issues, neuropharmacology, and a list of support groups for the elderly neurologically or mentally impaired in Brazil, Canada, Germany, the United Kingdom, and the USA.
Download or read book The Neurology of Aging written by Robert Katzman and published by F. A. Davis Company. This book was released on 1983 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Alzheimer s Disease Epidemiology Neuropathology Neurochemistry and Clinics written by Konrad Maurer and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book Alzheimer's Disease - Epidemiology, Neuropathology, Neurochemistry, and Clinics is derived from an International Symposium on the occasion of the 125th Anniversary of the Birth of Alois Alzheimer (14.6.1864-19.12.1915). Over the past decade, as the elderly have become the fastest-growing segment of the population in industrialized countries, Alzheimer's disease has emerged as one of the major mental health problems. The contributors to this book represent internationally recognized authorities in the field of dementia and present new information about epidemiology, neuropathology, neurochemistry, and clinics in Alzheimer's disease. This book is a rich and valuable up-to-date resource for psychiatrists, neurologists, scientists working in the fields of neuropathology, neurochemistry and molecular genetics, behavioral scientists, family physicians and all who share an interest in understanding and treating the older individual with Alzheimer's disease/dementia.
Download or read book Neurodevelopment Aging and Cognition written by KNEZEVIC and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: It was Oscar Wilde who defined the tragedy of old age by saying that " . . . as soon as you are old enough to know better, you don't know anything at all. " As improvements in the quality of health care bring about longer life, our attention has turned from the prolonging of life to the maintenance of involvement in life. In developed nations, a full 100% increase in the ranks of the elderly has appeared and with the benefits of this prolongation have come new and greater needs of the elderly cohort. Our interest is in those processes that may lead to dementia among the elderly, for in dementia we see a thief that robs victims of their memories and their place in life. This text was conceived and developed from an international con ference on neurodevelopment, aging, and cognition; the purpose of this few days a group of experts in these conference was to bring together for a fields from around the world to generate a dialog on common themes and unresolved problems. Our hope was that by keeping the meeting small and informal, we could break through barriers of terminology unique to the areas of developmental neurobiology, neuroscience, cognitive sci ence, and clinical medicine, and have a meaningful discussion on pro cesses that affect the biological integrity and cognitive performance of the aging nervous system.
Download or read book Ageing and Dementia written by Kurt Jellinger and published by Springer Science & Business Media. This book was released on 2002-08-20 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epidemiological studies, modern clinical, neuroimaging, neuropsychological, molecular biological, and genetic studies have considerably enhanced our knowledge about ageing processes of the human brain, its sequelae, diagnostic, and therapeutic possibilities and limits. In addition to Alzheimer's disease and other degenerative dementias, the impact of cerebrovascular lesions and their risk factors in the pathogenesis of cognitive disorders of the aged are increasingly acknowledged, and the recognition of mild cognitive impairment as a frequent initial stage of developing dementia is becoming an increasingly important diagnostic and therapeutic problem. The included papers were presented at the 7th International Symposium in Graz, Sept. 2001 and give a timely overview of the current and future concepts of pathogenesis, diagnosis, and treatment strategies of pathological brain ageing and dementias, early recognition of mild cognitive impairment and future possiblities of prevention of dementing processes.
Download or read book A Multidisciplinary Approach to Capability in Age and Ageing written by Hanna Falk Erhag and published by Springer Nature. This book was released on 2022-01-10 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book provides insight on how to interpret capability in ageing – one’s individual ability to perform actions in order to reach goals one has reason to value – from a multidisciplinary approach. With for the first time in history there being more people in the world aged 60 years and over than there are children below the age of 5, the book describes this demographic trends as well as the large global challenges and important societal implications this will have such as a worldwide increase in the number of persons affected with dementia, and in the ratio of retired persons to those still in the labor market. Through contributions from many different research areas, it discussed how capability depends on interactions between the individual (e.g. health, genetics, personality, intellectual capacity), environment (e.g. family, friends, home, work place), and society (e.g. political decisions, ageism, historical period). The final chapter summarizes the differences and similarities in these contributions. As such this book provides an interesting read for students, teachers and researchers at different levels and from different fields interested in capability and multidisciplinary research.
Download or read book Practical Dementia Care written by Peter V. Rabins and published by Oxford University Press. This book was released on 2006-01-19 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive yet practical guide to the care and management of patients with dementia from the time of diagnosis to the end of life. It is intended for the increasing number of physicians, nurses, psychologists, social workers, rehabilitation therapists, and long-term care givers responsible for the care of individuals with dementia. For the Second Edition, the authors have added a chapter on mild cognitive impairment. The sections that received the most extensive revision or expansion include those on drug therapy; the pathophysiology of several causes of dementia; psychiatric symptoms of dementia and their treatment (especially drug treatment); and dementia in special environments (especially assisted living and nursing homes).
Download or read book Aging and the Brain written by Robert D. Terry and published by . This book was released on 1988 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:
