Download or read book Neuroendocrine Molecular Biology written by G. Fink and published by . This book was released on 2014-09-01 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neuroendocrine Molecular Biology written by G. Fink and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 13th Annual Meeting of the Foundation was held in Edinburgh during September 1985. The subject was neuroendocrine molecular biology which brought together leading scientists in the fields of molecular genetics, neuroendocrinology and developmental neuro biology. The conference was most stimulating and as the Proceedings show, novel data presented was of the highest quality. The topics presented were grouped under the headings;, "Molecular Biology of the Nervous System", ''IlIRH - New Perspectives', ''Neuropeptides'', "Oxytocin and Vasopressin", "Transcriptional and Post-Translational Regulation of Neuropeptide Synthesis", "Neuroendocrine Mechanisms at the Cellular Level", "Receptors - Cellular and Molecular Biology" and "Clinical Applications". The
Download or read book Neuroendocrine Tumours written by Suayib Yalcin and published by Springer. This book was released on 2015-05-27 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a timely textbook that covers all aspects of neuroendocrine tumors (NET) from epidemiology, pathological classification and evaluation and molecular biology through to diagnostic imaging methods and therapeutic options, including the latest targeted therapies. The various types of NET are individually discussed, including carcinoid tumors, insulinomas, gastrinomas, glucagonomas, VIPomas, somatostatinomas, PPomas, medullary thyroid carcinomas, adrenocortical cancer, pheochromocytomas, paragangliomas and non-functioning pancreatic NETs. The contributing authors are internationally recognized experts who bring a wealth of experience to the subject. This book will be an invaluable source of information for practicing medical oncologists, surgeons, endocrinologists, gastroenterologists and pathologists and also trainees.
Download or read book Neuroendocrine Molecular Biology written by G. Fink and published by Springer. This book was released on 2012-06-14 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 13th Annual Meeting of the Foundation was held in Edinburgh during September 1985. The subject was neuroendocrine molecular biology which brought together leading scientists in the fields of molecular genetics, neuroendocrinology and developmental neuro biology. The conference was most stimulating and as the Proceedings show, novel data presented was of the highest quality. The topics presented were grouped under the headings;, "Molecular Biology of the Nervous System", ''IlIRH - New Perspectives', ''Neuropeptides'', "Oxytocin and Vasopressin", "Transcriptional and Post-Translational Regulation of Neuropeptide Synthesis", "Neuroendocrine Mechanisms at the Cellular Level", "Receptors - Cellular and Molecular Biology" and "Clinical Applications". The
Download or read book Neuroendocrine Tumors Review of Pathology Molecular and Therapeutic Advances written by Aejaz Nasir and published by Springer. This book was released on 2016-08-31 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive subspecialty reference book on NeuroEndocrine Tumor (NET) pathology brings together the diagnostic and clinical expertise of an outstanding team of practicing neuroendocrine pathologists and oncologists. In addition to in-depth coverage of clinico-pathologic aspects of NETs of the various organ systems, the recent histological grading and staging schemes proposed by the North American and European NeuroEndocrine Tumor Societies (NANETS, ENETS), the World Health Organization (WHO) and the American Joint Committee on Cancer (AJCC), this book also focuses on the recent molecular and therapeutic advances in the field of NET pathology and oncology. Neuroendocrine Tumors: Review of Pathology, Molecular and Therapeutic Advances will be an essential reference book for anatomic pathology (histopathology) residents, fellows, surgical pathologists, researchers, oncologists, surgeons and other medical professionals practicing advanced NET Pathology and Oncology in academia, community, private practice and research settings.
Download or read book Neuroendocrine Tumors written by James C. Yao and published by Springer Science & Business Media. This book was released on 2011-07-12 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: New research has shown that neuroendocrine tumors are more common than previously thought. Progress in our understanding of the molecular pathogenesis of these not-so-rare cancers has resulted in renewed interest in developing innovative therapeutic options. In particular, novel molecular targeted agents have been shown to have significant anti-tumor activity, and integration of these therapies has led to critical advances in management. In this volume, an outstanding group of the world’s leaders in the field have assembled to convey their knowledge of the epidemiology, biology, and management of all the major types of neuroendocrine tumors. The book takes a multi-modality approach to understanding disease processes and therapeutics, including chapters on medical and surgical treatment as well as a chapter devoted to imaging. Throughout, the authors emphasize recent advances in our understanding of molecular biology and the subsequent emerging therapeutic options.
Download or read book Molecular Neuroendocrinology written by David Murphy and published by John Wiley & Sons. This book was released on 2016-03-07 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Neuroendocrinology: From Genome to Physiology, provides researchers and students with a critical examination of the steps being taken to decipher genome complexity in the context of the expression, regulation and physiological functions of genes in neuroendocrine systems. The 19 chapters are divided into four sectors: A) describes and explores the genome, its evolution, expression and the mechanisms that contribute to protein, and hence biological, diversity. B) discusses the mechanisms that enhance peptide and protein diversity beyond what is encoded in the genome through post-translational modification. C) considers the molecular tools that today’s neuroendocrinologists can use to study the regulation and function of neuroendocrine genes within the context of the intact organism. D) presents a range of case studies that exemplify the state-of-the-art application of genomic technologies in physiological and behavioural experiments that seek to better understand complex biological processes. • Written by a team of internationally renowned researchers • Both print and enhanced e-book versions are available • Illustrated in full colour throughout This is the third volume in a new Series ‘Masterclass in Neuroendocrinology’ , a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology. Series Editors: John A. Russell, University of Edinburgh, UK and William E. Armstrong, The University of Tennessee, USA
Download or read book Neuroendocrinology written by David A. Lovejoy and published by John Wiley & Sons. This book was released on 2005-11-01 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been an explosion of interest in the field of neuroendocrinology over the last twenty years with the discovery of neurohormones regulating virtually everything from growth and development to sexual and aggressive behavior. This book provides a much-needed introduction to neuroendocrinology from a zoological and evolutionary perspective. It covers the evolution, development and description of the neuroendocrine system throughout the animal kingdom. Specific topics covered include: The Evolution of early neuroendocrine systems in primitive animals Structural characterisation, molecular biology and biochemistry of neuroendocrine agents A profiles section on unusual aspects of neuroendocrine physiology written by leaders in the field A unique section on the actions of environmental chemicals effect neuroendocrine systems in various species
Download or read book Neuroendocrine Neoplasia Management written by Giordano Beretta and published by Springer Nature. This book was released on 2021-07-16 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the most recent update on the management of neuroendocrine neoplasia (NEN), a term covering all tumors of various organs and/or with a particular histology, including MEN (multiple endocrine neoplasia) related tumors, MiNEN (mixed neuroendocrine-non-neuroendocrine neoplasms), NEC (neuroendocrine carcinoma) and Merkel’s carcinoma. NENs are heterogeneous in their biology, clinical presentation and prognosis, showing a great variability in aggressiveness and therapy response. As a result, their treatment is based on a large spectrum of options. The standard therapies are surgery in early disease, various loco-regional procedures in certain conditions and mostly of a palliative nature in metastatic disease. At present, thanks to our increased understanding of molecular signaling pathways, several pharmacological approaches can be used in patients with advanced NENs. Somatostatin analogs display both anti-tumor effects and symptom control. Novel peptide-radio-receptor treatment (PRRT) is used in patients with well differentiated tumors. The agents targeting angiogenesis and/or PI3K/AKT/mTOR pathway, alone or in combination with analogues, have provided encouraging results in advanced disease. The first part of the book focuses on the history, epidemiology and the most relevant scientific achievements, covering the discoveries in genetic and molecular biology, the endoscopic techniques with guided biopsy, and the metabolic imaging with hybrid PET/CT and MRI/CT. It particularly highlights the emerging strategies in therapy, surgery and mini-invasive surgery as well as loco-regional and systemic treatments, including targeted therapy and/or biological therapies. The second part then explores the management of NENs of various anatomical origins and/or with peculiar biology. It describes the range of the current options and the most relevant results from the clinical trials. This informative book provides valuable insights for all those interested in the management of neuroendocrine neoplasia.
Download or read book Gastroenteropancreatic Neuroendocrine Tumor Disease written by Bertram Wiedenmann and published by . This book was released on 2004 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: At the beginning of the last century, the development of the Neuroendocrine Concept sparked intensive and worldwide research efforts leading to fascinating insights into the complex and diverse system of neuroendocrine cells and its importance in human physiology and disease. Recent developments in new and expanding research areas, including developmental biology, regulation of angiogenesis, cellular signaling and transcription, and impressive results obtained by application of genomics and proteomics warranted a reevaluation of the neuroendocrine concept. impact of the current understanding of neuroendocrine biology and pathobiology in these research areas. In particular, new discoveries are presented in neuroendocrine developmental biology with special emphasis on transcription factors controlling neuroendocrine differentiation of endodermal stem cells. controlling formation and proliferation of blood and lymphatic vessels and molecular determinants of hematogenous and lymphatic tumor dissemination. Given their central importance for the establishment and maintenance of the neuroendocrine phenotype, signal transduction cascades and their cellular targets related to the regulation of adhesion processes, receptor-mediated endocytosis, and cell cycle events as well as secretory activation and membrane trafficking are discussed in the context of neuroendocrine physiology and neuroendocrine tumor disease. Since many of the recent discoveries made in basic research can be directly linked to clinical applications, this volume summarizes and discusses innovative treatment and/or diagnostic approaches for neuroendocrine tumor disease.
Download or read book Molecular and Cell Biological Aspects of Gastroenteropancreatic Neuroendocrine Tumor Disease written by Bertram Wiedenmann and published by . This book was released on 1994 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: New molecular and cell biological approaches in the fields of neurobiology and neuroendocrinology have identified a large number of molecules that can be assigned structurally and functionally to various subcellular structures, such as secretory vesicles, the Golgi complex, the trans-Golgi network, and endosomes. It has become evident that neurons and neuroendocrine cells share many properties, such as the expression of very similar secretory vesicles and molecules, including cell adhesion molecules, neurotransmitters, hormones, neurotransmitter-receptors and hormone-receptors. Various molecules discovered and characterised in basic research have been found to be increasingly applicable for improved diagnosis and therapy of neuroendocrine tumour disease. This volume reviews current research in both basic science and clinical research from the viewpoint of its direct applicability to clinical medicine.
Download or read book Neuroendocrine immune Interactions written by Rolf C. Gaillard and published by Karger Medical and Scientific Publishers. This book was released on 2002 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interactions between the immune, endocrine and nervous systems seldom appear as main issues in the neurosciences and in immunology. So far this was most likely due to the need to focus on the molecular and cellular bases of single neural, endocrine and immune processes. But hormones, neurotransmitters and neuropeptides can also influence more subtle mechanisms underlying immune cell activity. The contents of this volume aim at listing some aspects which show that not only the bases for neuroendocrine control of more refined mechanisms related to the organization and functioning of the immune systems to exist, but also that the immune system can actively communicate with neuroendocrine structures. The evidence is divided into three categories: - Anatomical, cellular and molecular bases for the exchange of information between immune, endocrine and neural cells, - reciprocal effects between immune and neuroendocrine mechanisms, and - immune-neuroendocrine regulatory circuits. Immunologically triggered neuroendocrine responses can be either beneficial or deleterious for the host. A systematic approach would imply the simultaneous evaluation of neuroendocrine and immune parameters and thus provide the basis for therapeutic interventions based on antagonizing or blocking undesirable effects.
Download or read book Neuroendocrine Peptide Methodology written by P. Michael Conn and published by Elsevier. This book was released on 2012-12-02 with total page 982 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroendocrine Peptide Methodology
Download or read book Neuroendocrinology written by Horst-Werner Korf and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: 70 years after the discovery of secretory neurons, internationally leading experts gathered to discuss the latest developments in neuropeptide research and endocrinology, concentrating on the molecular, cellular, supracellular and systemic aspects. A variety of neuropeptidergic systems are considered under comparative and evolutionary aspects.
Download or read book Handbook of Neuroendocrinology written by George Fink and published by Academic Press. This book was released on 2012 with total page 895 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroendocrinology underpins fundamental physiological, molecular, biological, and genetic principles such as the regulation of gene transcription and translation. This handbook highlights the experimental and technical foundations of each area's major concepts and principles.
Download or read book Diagnostic and Therapeutic Nuclear Medicine for Neuroendocrine Tumors written by Karel Pacak and published by Humana Press. This book was released on 2016-12-26 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the most novel approaches and cutting-edge clinical and scientific information regarding radionuclide imaging and therapies for neuroendocrine tumors, this clinical guidebook represents a unique collaborative effort between endocrinologists, nuclear physicians, oncologists, surgeons, physicists, radio-pharmacists and geneticists. It begins with the embryology, classification and molecular genetics of gastroenteropancreatic neuroendocrine tumors and carcinoids, chromaffin cell tumors, and MEN1- and MEN2-related tumors. Following a chapter on radiopharmaceuticals in neuroendocrine imaging, it turns to the physics and technology of current and cutting-edge radiology, including SPECT/CT and PET/CT and PET/MR. Discussing of radionuclide imaging covers the tumors mentioned above, as well as pulmonary and thymic neuroendocrine tumors and medullary thyroid carcinoma. A presentation of radionuclide therapies follows, including 131I-MIBG therapy, somatostatin receptor-based therapy, and alpha radionuclide therapy, as well as the role of nanoparticles. Comprehensive and up-to-date, Diagnostic and Therapeutic Nuclear Medicine for Neuroendocrine Tumors will assist and guide physicians who encounter patients with these conditions, either from a diagnostic or therapeutic standpoint, and particularly emphasizes the current and emerging medical devices and imaging and therapeutic options.
Download or read book Textbook of Energy Balance Neuropeptide Hormones and Neuroendocrine Function written by Eduardo A. Nillni and published by Springer. This book was released on 2018-07-20 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook presents for the first time a comprehensive body of the latest knowledge in the field of neuropeptides and their action on energy balance. It contains a detailed and comprehensive account of the specific hypothalamic peptides in regards to their roles in energy balance, food intake control and co-morbidities, to better understand the patho-physiology of obesity. The textbook includes an examination the history of the evolution of human society from a thin to the obese phenotype and, within that context, how modern society habits and industrial food production did not respect the evolutionary trait resulting in changes in the energy balance set point. It provides a novel conceptualization of the problem of obesity when considering the biochemistry of peptide hormones and entertaining novel ideas on multiple approaches to the problems of energy balance, as well as demonstrates and explains why alterations in pro-hormone processing are paramount to understand metabolic disease. This text is excellent material for teaching graduate and medical school courses, as well as a valuable resource for researchers in biochemistry, cell, and molecular biology, neuroscientists, physician endocrinologists, and nutritionists.
