Download or read book Neural Interface Engineering for Electrophysiology Application written by Hyungsoo Kim and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is a wondrous and complex organ, a biological machine forged by the evolutionary forces of nature. The human brain contains 100 billion neurons and each neuron is connected by synapses to several thousand other neurons. Connected neurons work together to produce perceptions and sensations, memories and emotions, physical movements and abstract constructs. The neurons communicate by means of electricity that passes along and across their cellular membrane. Much of what is known about brain physiology is through the measurement of this electrical activity, either with relatively large electrodes placed on the scalp or tiny microelectrodes inserted into the brain tissue itself. At the finer end of this scale, scientists have discovered much about the way individual neurons extract sensory information, adapt their behavior to form a memory, and convey signals to other regions of the brain. However, it has long been recognized that the brain operates on a global scale, through the collective behavior and interaction of its neural units1. Information is processed in several regions of the brain simultaneously, and the activity of neighboring neurons can be quite different from one another. By one analogy, the attempt to assess brain function by observing a single neuron is like looking at the output of one transistor to learn how a computer works. Thus, the recording of many neurons simultaneously is necessary to truly reveal the mechanisms of the brain2. In recent decades, a variety of recording techniques have been developed for a neural interface such as electroencephalography (EEG), magneto-encephalography (MEG), electrocorticography (ECOG), local field potential (LFP) recordings, micro-electrode array (MEA) and peripheral nerve interfaces (PNIs) to the micron-level precision required for multi-neuron recording. Their small size allows many recording channels to be placed onto one device. One of the goals of neural interface research is to create a seamless connection between the nervous system and the neuroprostheses either by stimulating or by recording from neural tissue to restore or substitute function for individuals with neurological deficits or disabilities. Hence, significant amount of scientific and technological efforts have been devoted to develop neural interfaces that link the nervous system with robotic prosthetic devices. The creation of a novel neural interface is essential for developing the full potential of advanced prosthesis technology required to replace lost limbs. Additionally, meticulous studies of a single neuron and between neurons utilizing the neural interface technology should be made to elucidate fundamental biological phenomena such as cellular processes and heterogeneities. Particularly, an electrophysiological study of neural networks can provide knowledge to unravel the functions of brain. When fundamental research about molecular and cellular mechanisms of a single neuron and electrophysiological studies using neural interfaces on both the central and peripheral nervous systems are done together, it has a synergistic effect on neural interface technology. The research and methodologies described in this dissertation stem from our research group's efforts to optimize the design and expand the applications of neural interfaces. The dissertation is organized into four chapters. Chapter 1 is a review of neural interface technology and study of neural signal detection. This chapter provides a foundation for Chapter 2 and 3. Chapter 2 is a study of a neural interface as cellular level research. We present an advanced single-neuronal cell culture and monitoring platform using a fully transparent microfluidic dielectrophoresis (DEP) device for unabated monitoring of neuronal cell development and function. The device is mounted inside a sealed incubation chamber to ensure improved homeostatic conditions and reduced contamination risk. Consequently, we successfully trap and culture single neurons on a desired location and monitor their growth process over a week. Chapter 3 deals with the specific application of PNIs to the sciatic nerve of a rat as a nervous system-level research. We developed novel devices, "cuff and sieve electrodes" (CASE), that integrate microfabricated cuff and sieve electrodes capable of broad (via cuff) and precise (via sieve) selectivity to increase the strengths and simultaneously decrease the weaknesses of traditional electrode designs. We performed terminal device implantations in a rat sciatic transection and repair model to test the capacity of the CASE interface. The sciatic nerve was stimulated by the sieve portion of the CASE electrode and somatosensory evoked potentials were recorded from the somatosensory cortex via micro-eletrocorticography. The ability to elicit cortical responses from sciatic nerve stimulation demonstrates the proof of concept for both the implantation and chronic monitoring of CASE interfaces for innovative prosthetic control. Lastly, in Chapter 4, I will identify areas in which further investigation is needed and propose future directions of both cellular and system-level neural interface

Download or read book Neural Interface Engineering written by Liang Guo and published by Springer Nature. This book was released on 2020-05-04 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive reference to major neural interfacing technologies used to transmit signals between the physical world and the nervous system for repairing, restoring and even augmenting body functions. The authors discuss the classic approaches for neural interfacing, the major challenges encountered, and recent, emerging techniques to mitigate these challenges for better chronic performances. Readers will benefit from this book’s unprecedented scope and depth of coverage on the technology of neural interfaces, the most critical component in any type of neural prostheses. Provides comprehensive coverage of major neural interfacing technologies; Reviews and discusses both classic and latest, emerging topics; Includes classification of technologies to provide an easy grasp of research and trends in the field.

Download or read book Brain Machine Interface Engineering written by Justin Sanchez and published by Springer Nature. This book was released on 2022-06-01 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural interfaces are one of the most exciting emerging technologies to impact bioengineering and neuroscience because they enable an alternate communication channel linking directly the nervous system with man-made devices. This book reveals the essential engineering principles and signal processing tools for deriving control commands from bioelectric signals in large ensembles of neurons. The topics featured include analysis techniques for determining neural representation, modeling in motor systems, computing with neural spikes, and hardware implementation of neural interfaces. Beginning with an exploration of the historical developments that have led to the decoding of information from neural interfaces, this book compares the theory and performance of new neural engineering approaches for BMIs. Contents: Introduction to Neural Interfaces / Foundations of Neuronal Representations / Input-Outpur BMI Models / Regularization Techniques for BMI Models / Neural Decoding Using Generative BMI Models / Adaptive Algorithms for Point Processes / BMI Systems

Download or read book Brain machine Interface Engineering written by Justin Cort Sanchez and published by Morgan & Claypool Publishers. This book was released on 2007 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation Brain-Machine Interaction provides a unique framework for understanding the motivation and techniques of applying signal processing methodologies to brain-machine interaction (BMI) design and experimentation. Each chapter begins with a historical perspective and motivating example illustrating the need for this approach in BMI design. Included in each chapter is a list of assumptions associated with each methodological choice and the impact on BMI performance. To validate and advance the state-of-the-art of BMI modeling design, model performance is discussed and how the proposed model represents the neural-to-motor mappings. Finally, the feasibility of building BMIs (technical and practical aspects) is developed in the context of digital computational hardware.

Download or read book Principles of Electrical Neural Interfacing written by Liang Guo and published by Springer Nature. This book was released on 2021-09-29 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook fills a gap to supply students with the fundamental principles and tools they need to perform the quantitative analyses of the neuroelectrophysiological approaches, including both conventional and emerging ones, prevalently used in neuroscience research and neuroprosthetics. The content grows out of a course on Neuroengineering and Neuroprosthetics, which the author has taught already several times. The key problems the author addresses include (1) the universal operating mechanisms of neuroelectrophysiological approaches, (2) proper configuration of each approach, and (3) proper interpretation of the resulting signals. Efforts are made both to extract the universal principles underlying this common class of approaches and discern the unique properties of each individual approach. To address these important problems, equivalent electrical circuit modeling and signal analysis are used to unravel the functioning mechanisms and principles and provide sound interpretations to the associated signals and phenomena. This book aims to derive analytical solutions to these equivalent circuits, which can offer clear and complete mechanistic insights to the underlying biophysics.

Download or read book Electrophysiology Measurements for Studying Neural Interfaces written by Mohammad M. Aria and published by Academic Press. This book was released on 2020-05-15 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electrophysiology Measurements for Studying Neural Interfaces helps readers to choose a proper cell line and set-up for studying different bio-electronic interfaces before delving into the electrophysiology techniques available. Therefore, this book details the materials and devices needed for different types of neural stimulation such as photoelectrical and photothermal stimulations. Also, modern techniques like optical electrophysiology and calcium imaging in this book provides readers with more available approaches to monitor neural activities in addition to whole-cell patch-clamp technology. Details steps of an electrophysiology project from start to finish for graduate students employing the technique in their research Includes sample electrophysiological studies with multiple cell lines (PC12, N2a, NG108, SHSY, and embryonic stem cell lines) to facilitate research Features data analysis of electrophysiology results from various relevant experiments and cell culture tips

Download or read book Brain and Behavior Computing written by Mridu Sahu and published by CRC Press. This book was released on 2021-06-23 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain and Behavior Computing offers insights into the functions of the human brain. This book provides an emphasis on brain and behavior computing with different modalities available such as signal processing, image processing, data sciences, statistics further it includes fundamental, mathematical model, algorithms, case studies, and future research scopes. It further illustrates brain signal sources and how the brain signal can process, manipulate, and transform in different domains allowing researchers and professionals to extract information about the physiological condition of the brain. Emphasizes real challenges in brain signal processing for a variety of applications for analysis, classification, and clustering. Discusses data sciences and its applications in brain computing visualization. Covers all the most recent tools for analysing the brain and it’s working. Describes brain modeling and all possible machine learning methods and their uses. Augments the use of data mining and machine learning to brain computer interface (BCI) devices. Includes case studies and actual simulation examples. This book is aimed at researchers, professionals, and graduate students in image processing and computer vision, biomedical engineering, signal processing, and brain and behavior computing.

Download or read book Neural Interface Frontiers and Applications written by Xiaoxiang Zheng and published by Springer Nature. This book was released on 2019-11-15 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the frontiers of neural interface technology, including hardware, software, neural decoding and encoding, control systems, and system integration. It also discusses applications for neuroprosthetics, neural diseases and neurorobotics, and the toolkits for basic neuroscience. A neural interface establishes a direct communication channel with the central or peripheral nervous system (CNS or PNS), and enables the nervous system to interact directly with the external devices. Recent advances in neuroscience and engineering are speeding up neural interface technology, paving the way for assisting, augmenting, repairing or restoring sensorimotor and other cognitive functions impaired due to neurological disease or trauma, and so improving the quality of life of those affected. Neural interfaces are now being explored in applications as diverse as rehabilitation, accessibility, gaming, education, recreation, robotics and human enhancement. Neural interfaces also represent a powerful tool to address fundamental questions in neuroscience. Recent decades have witnessed tremendous advances in the field, with a huge impact not only in the development of neuroprosthetics, but also in our basic understanding of brain function. Neural interface technology can be seen as a bridge across the traditional engineering and basic neuroscience. This book provides researchers, graduate and upper undergraduate students from a wide range of disciplines with a cutting-edge and comprehensive summary of neural interface engineering research.

Download or read book Engineering Biomaterials for Neural Applications written by Elisa López-Dolado and published by Springer Nature. This book was released on 2022-03-25 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes past and present advances in engineering materials for neural applications, with special emphasis on their usefulness for traumatic brain and spinal cord injuries. The book presents major physio-pathological features of traumatic injuries at the brain and spinal cord as examples of diseases hampering the central nervous tissue. By incorporating knowledge from the perspective of experts with diverse backgrounds, this book gives insight into the understanding of these multifaceted pathologies and the materials science approaches that aim to cure them. The interdisciplinary nature of this book makes it a perfect candidate for the interest of a broad audience, from clinicians working on neural diseases to scientists whose work focuses on the nervous tissue (neuroscientists) and/or materials science. Undergraduate and PhD students can also benefit from the knowledge and discussion included in this book.

Download or read book Brain Computer Interfaces Handbook written by Chang S. Nam and published by CRC Press. This book was released on 2018-01-09 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain–Computer Interfaces Handbook: Technological and Theoretical Advances provides a tutorial and an overview of the rich and multi-faceted world of Brain–Computer Interfaces (BCIs). The authors supply readers with a contemporary presentation of fundamentals, theories, and diverse applications of BCI, creating a valuable resource for anyone involved with the improvement of people’s lives by replacing, restoring, improving, supplementing or enhancing natural output from the central nervous system. It is a useful guide for readers interested in understanding how neural bases for cognitive and sensory functions, such as seeing, hearing, and remembering, relate to real-world technologies. More precisely, this handbook details clinical, therapeutic and human-computer interfaces applications of BCI and various aspects of human cognition and behavior such as perception, affect, and action. It overviews the different methods and techniques used in acquiring and pre-processing brain signals, extracting features, and classifying users’ mental states and intentions. Various theories, models, and empirical findings regarding the ways in which the human brain interfaces with external systems and environments using BCI are also explored. The handbook concludes by engaging ethical considerations, open questions, and challenges that continue to face brain–computer interface research. Features an in-depth look at the different methods and techniques used in acquiring and pre-processing brain signals, extracting features, and classifying the user's intention Covers various theories, models, and empirical findings regarding ways in which the human brain can interface with the systems or external environments Presents applications of BCI technology to understand various aspects of human cognition and behavior such as perception, affect, action, and more Includes clinical trials and individual case studies of the experimental therapeutic applications of BCI Provides human factors and human-computer interface concerns in the design, development, and evaluation of BCIs Overall, this handbook provides a synopsis of key technological and theoretical advances that are directly applicable to brain–computer interfacing technologies and can be readily understood and applied by individuals with no formal training in BCI research and development.

Download or read book Neural Engineering written by Bin He and published by Springer Nature. This book was released on 2020-09-21 with total page 707 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition overviews the essential contemporary topics of neuroengineering, from basic principles to the state-of-the-art, and is written by leading scholars in the field. The book covers neural bioelectrical measurements and sensors, EEG signal processing, brain-computer interfaces, implantable and transcranial neuromodulation, peripheral neural interfacing, neuroimaging, neural modelling, neural circuits and system identification, retinal bioengineering and prosthetics, and neural tissue engineering. Each chapter is followed by homework questions intended for classroom use. This is an ideal textbook for students at the graduate and advanced undergraduate level as well as academics, biomedical engineers, neuroscientists, neurophysiologists, and industry professionals seeking to learn the latest developments in this emerging field. Advance Praise for Neural Engineering, 3rd Edition: “A comprehensive and timely contribution to the ever growing field of neural engineering. Bin He’s edited volume provides chapters that cover both the fundamentals and state-of-the-art developments by the world’s leading neural engineers." Dr. Paul Sajda, Department of Biomedical Engineering, Electrical Engineering and Radiology, Columbia University “Neural Engineering, edited by Prof. He, is an outstanding book for students entering into this fast evolving field as well as experienced researchers. Its didactic and comprehensive style, with each chapter authored by leading scientific authorities, provides the ultimate reference for the field.” Dr. Dario Farina, Department of Bioengineering, Imperial College London, London, UK "Neural Engineering has come of age. Major advances have made possible prosthesis for the blind, mind control for quadraplegics and direct intervention to control seizures in epilepsy patients. Neural Engineering brings together reviews by leading researchers in this flourishing field. Dr. Terrence Sejnowski, Salk Institute for Biolgical Studies and UC San Diego

Download or read book Neural signals acquisition and intelligent analysis written by Xiaomin Yang and published by Frontiers Media SA. This book was released on 2023-08-24 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Interface Engineering in Organic Field Effect Transistors written by Xuefeng Guo and published by John Wiley & Sons. This book was released on 2023-07-05 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interface Engineering in Organic Field-Effect Transistors Systematic summary of advances in developing effective methodologies of interface engineering in organic field-effect transistors, from models to experimental techniques Interface Engineering in Organic Field-Effect Transistors covers the state of the art in organic field-effect transistors and reviews charge transport at the interfaces, device design concepts, and device fabrication processes, and gives an outlook on the development of future optoelectronic devices. This book starts with an overview of the commonly adopted methods to obtain various semiconductor/semiconductor interfaces and charge transport mechanisms at these heterogeneous interfaces. Then, it covers the modification at the semiconductor/electrode interfaces, through which to tune the work function of electrodes as well as reveal charge injection mechanisms at the interfaces. Charge transport physics at the semiconductor/dielectric interface is discussed in detail. The book describes the remarkable effect of SAM modification on the semiconductor film morphology and thus the electrical performance. In particular, valuable analyses of charge trapping/detrapping engineering at the interface to realize new functions are summarized. Finally, the sensing mechanisms that occur at the semiconductor/environment interfaces of OFETs and the unique detection methods capable of interfacing organic electronics with biology are discussed. Specific sample topics covered in Interface Engineering in Organic Field-Effect Transistors include: Noncovalent modification methods, charge insertion layer at the electrode surface, dielectric surface passivation methods, and covalent modification methods Charge transport mechanism in bulk semiconductors, influence of additives on materials’ nucleation and morphology, solvent additives, and nucleation agents Nanoconfinement effect, enhancing the performance through semiconductor heterojunctions, planar bilayer heterostructure, ambipolar charge-transfer complex, and supramolecular arrangement of heterojunctions Dielectric effect in OFETs, dielectric modification to tune semiconductor morphology, surface energy control, microstructure design, solution shearing, eliminating interfacial traps, and SAM/SiO2 dielectrics A timely resource providing the latest developments in the field and emphasizing new insights for building reliable organic electronic devices, Interface Engineering in Organic Field-Effect Transistors is essential for researchers, scientists, and other interface-related professionals in the fields of organic electronics, nanoelectronics, surface science, solar cells, and sensors.

Download or read book Biomedical Engineering Applications for People with Disabilities and the Elderly in the COVID 19 Pandemic and Beyond written by Valentina Emilia Balas and published by Academic Press. This book was released on 2022-06-18 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical Engineering Applications for People with Disabilities and the Elderly in the COVID-19 Pandemic and Beyond presents biomedical engineering applications used to manage people’s disabilities and care for the elderly to improve their quality of life and extend life expectancy. This edited book covers all aspects of assistive technologies, including the Internet of Things (IoT), telemedicine, e-Health, m-Health, smart sensors, robotics, devices for rehabilitation, and "serious" games. This book will prove useful for bioengineers, computer science undergraduate and postgraduate students, researchers, practitioners, biomedical engineering students, healthcare workers, and medical doctors. This volume introduces recent advances in biomaterials, sensors, cellular engineering, biomedical devices, nanotechnology, and biomechanics applied in caring for the elderly and people with disabilities. The unique focus of this book is on the needs of this user base during emergency and disaster situations. The content includes risk reduction, emergency planning, response, disaster recovery, and needs assessment. This book offers readers multiple perspectives on a wide range of topics from a variety of disciplines. This book answers two key questions: What challenges will the elderly and people with disabilities face during a pandemic? How can new (or emerging) advances in biomedical engineering help with these challenges? Includes coverage of smart protective care tools, disinfectants, sterilization equipment and equipment for rapid and accurate COVID-19 diagnosis Focuses on the limitations and challenges faced by the elderly and people with disabilities in pandemic situations, such as limitations on leaving their homes and having caregivers and family visit their homes. How can technology help? Discusses tools, platforms and techniques for managing patients with COVID-19

Download or read book Biometry written by Ricardo A. Ramirez-Mendoza and published by CRC Press. This book was released on 2022-07-07 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biometrics provide quantitative representations of human features, physiological and behavioral. This book is a compilation of biometric technologies developed by various research groups in Tecnologico de Monterrey, Mexico. It provides a summary of biometric systems as a whole, explaining the principles behind physiological and behavioral biometrics and exploring different types of commercial and experimental technologies and current and future applications in the fields of security, military, criminology, healthcare education, business, and marketing. Examples of biometric systems using brain signals or electroencephalography (EEG) are given. Mobile and home EEG use in children’s natural environments is covered. At the same time, some examples focus on the relevance of such technology in monitoring epileptic encephalopathies in children. Using reliable physiological signal acquisition techniques, functional Human Machine Interfaces (HMI) and Brain-Computer Interfaces (BCI) become possible. This is the case of an HMI used for assistive navigation systems, controlled via voice commands, head, and eye movements. A detailed description of the BCI framework is presented, and applications of user-centered BCIs, oriented towards rehabilitation, human performance, and treatment monitoring are explored. Massive data acquisition also plays an essential role in the evolution of biometric systems. Machine learning, deep learning, and Artificial Intelligence (AI) are crucial allies here. They allow the construction of models that can aid in early diagnosis, seizure detection, and data-centered medical decisions. Such techniques will eventually lead to a more concise understanding of humans.

Download or read book Deep Learning For Eeg based Brain computer Interfaces Representations Algorithms And Applications written by Xiang Zhang and published by World Scientific. This book was released on 2021-09-14 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deep Learning for EEG-Based Brain-Computer Interfaces is an exciting book that describes how emerging deep learning improves the future development of Brain-Computer Interfaces (BCI) in terms of representations, algorithms and applications. BCI bridges humanity's neural world and the physical world by decoding an individuals' brain signals into commands recognizable by computer devices.This book presents a highly comprehensive summary of commonly-used brain signals; a systematic introduction of around 12 subcategories of deep learning models; a mind-expanding summary of 200+ state-of-the-art studies adopting deep learning in BCI areas; an overview of a number of BCI applications and how deep learning contributes, along with 31 public BCI data sets. The authors also introduce a set of novel deep learning algorithms aimed at current BCI challenges such as robust representation learning, cross-scenario classification, and semi-supervised learning. Various real-world deep learning-based BCI applications are proposed and some prototypes are presented. The work contained within proposes effective and efficient models which will provide inspiration for people in academia and industry who work on BCI.Related Link(s)

Download or read book Encyclopedia of Biomedical Engineering written by and published by Elsevier. This book was released on 2018-09-01 with total page 2069 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Biomedical Engineering, Three Volume Set is a unique source for rapidly evolving updates on topics that are at the interface of the biological sciences and engineering. Biomaterials, biomedical devices and techniques play a significant role in improving the quality of health care in the developed world. The book covers an extensive range of topics related to biomedical engineering, including biomaterials, sensors, medical devices, imaging modalities and imaging processing. In addition, applications of biomedical engineering, advances in cardiology, drug delivery, gene therapy, orthopedics, ophthalmology, sensing and tissue engineering are explored. This important reference work serves many groups working at the interface of the biological sciences and engineering, including engineering students, biological science students, clinicians, and industrial researchers. Provides students with a concise description of the technologies at the interface of the biological sciences and engineering Covers all aspects of biomedical engineering, also incorporating perspectives from experts working within the domains of biomedicine, medical engineering, biology, chemistry, physics, electrical engineering, and more Contains reputable, multidisciplinary content from domain experts Presents a ‘one-stop’ resource for access to information written by world-leading scholars in the field