Download or read book Comparative Oncology written by Alecsandru Ioan Baba and published by . This book was released on 2007 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Adenocarcinoma of the Prostate written by Andrew W. Bruce and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carcinoma of the prostate increasingly dominates the attention of urologists for both scientific and clinical reasons. The search for an explanation and the prediction of the variable behaviour of the malignant prostatic cell continues unabated. The search for more precise tumour staging and more effective treatment is equally vigorous. Editors Andrew Bruce and John Trachtenberg have assembled acknowledged leaders in prostate cancer to present those areas of direct interest to the clinician. There are a number of other topics that might have been considered but most of these, such as experimental tumour models or biochemical factors affecting cell growth, still lack immediate application for the clinician. Carcinoma of the prostate continues to have its highest incidence in the western world, and the difference in comparison with the incidence in the Far East appears to be real and not masked by diagnostic or other factors. A number of other epidemiological aspects need careful analysis: Is the incidence increasing? Is the survival improving? Is the prognosis worse in the younger patient? Epidemiological data are easily misused and misinterpreted so that a precise analysis of the known facts makes an important opening chapter to this book.

Download or read book Neoplasm written by Hafiz Shahzad and published by BoD – Books on Demand. This book was released on 2018-09-19 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neoplasm refers to an abnormal tissue growth that arises as a consequence of rapid cell proliferation and continues to grow abnormally even after terminating the stimuli that had instigated the change. It lacks partial or complete functional coordination with that of the normal tissues. Neoplasms are classified depending on the degree and type of tissues involved. Carcinogenesis is a multistep process where a plethora of endogenous and exogenous factors turns out genetic and epigenetic modifications, which collectively amend some critical cellular pathways controlling the proliferation, apoptosis, and differentiation. The cells having aberrant modifications are transformed into malignant ones of which the clonal expansion results in the development of cancer. This book provides the reader with a comprehensive overview of various cancer types along with their molecular mechanisms of initiation and progression. It also describes the current knowledge about the state-of-the-art measures being employed in cancer diagnosis and therapeutics. Particular attention is paid to make this book equally useful for students, practitioners, and expert scientists.

Download or read book Cancer Cell Structures Carcinogens and Genomic Instability written by Leon P. Bignold and published by Springer Science & Business Media. This book was released on 2006-01-27 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume began with an invitation from the publishers to edit a volume of EXS on Cancer. This invitation undoubtedly derived from my articles in Cellular and Molecular Life Sciences in 2002 and 2003 on the relationships between the morphology, aetiology and pathogenesis of tumours, especially in relation to genetic instability. After many years of teaching the theories of c- cer in undergraduate medical school courses, it seemed to me that the variably chaotic histopathologic features of tumours parallel in some way, the variably unstable genomes of tumour cells, which were being discovered in the 1990s. Thus the title of the volume has come to include morphology, carcinogenesis and genetic instability. The invitation came while I was working with Herrn Dr. med. Hubertus Jersmann (MD Düsseldorf, PhD, now Senior Lecturer in Medicine of the University of Adelaide) and Professor Brian Coghlan (Emeritus Professor of German, the University of Adelaide), on the work of the nineteenth century cancer pathologists, especially David Paul von Hansemann (1858–1920). With the delivery of the manuscripts from the authors of the chapters, it became obvious that a background chapter for the volume could include some of the material which we had “uncovered” together. Because of this, chapter 1 is authored by the three of us, and the “new” material figures prominently.

Download or read book Special Topics in Carcinogenesis written by E. Grundmann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts

Download or read book The Pathobiology of Neoplasia written by A.E. Sirica and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is directed primarily to advanced graduate and medical students, postdoctoral trainees, and established investigators having basic research interests in neoplasia. Its content is based in part on the lecture outlines and selected histopathology laboratory components of an advanced course entitled The Pathobiology of Experimental Animal and Human Neoplasia, developed by me for the Experimental Pathology Curriculum of the Department of Pathology at the Medical College of Virginia. In this regard, an effort has been made to integrate pathology with carcinogenesis, genetics, biochemistry, and cellular and molecular biology in order to present a comprehensive and current view of the neoplastic process. For focus, emphasis is mainly being placed on the neoplastic cells themselves, and not on associated host-mediated responses. It ishoped that this book will accomplish its purpose of providing students and researchers who already possess strong but diverse basic science backgrounds with unifying concepts in tumor pathobiology, so as to stimulate new research aimed at furthering our understanding of neoplastic disease. I wish to express my appreciation and heartfelt thanks to the authors, whose individual ranges of expertise and research experience clearly bring to their respective chapters unique perspectives that easily transcend any redundancy that may be present. In addition, I am grateful to Drs. George Vennart, Saul Kay, and Fred Meier, and to Ms. Connie Wilkerson of the Department of Pathology at MCV, for their helpful comments and their review of some of the material.

Download or read book Biochemistry of Cancer written by Jesse P. Greenstein and published by Elsevier. This book was released on 2013-10-22 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemistry of Cancer focuses on cancer research, including induction, chemical composition, and growth of tumors and chemotherapy. The book first offers information on the general phenomena and taxonomy of cancer. Discussions focus on the transmissibility of tumors and experimental basis of cancer research; cancerous transformation of animal tissues in vitro; growth and the vascular reactions of tumors; and classification of animal tumors. The text also ponders on the extrinsic factors in the induction of tumors, including comparative carcinogenicity of hydrocarbons, metabolic fate of injected hydrocarbons, dosage and response to carcinogenic hydrocarbons, and polycyclic hydrocarbons. The manuscript takes a look at the intrinsic factors in the induction of tumors. Topics include influence of sex hormones on carcinogenesis of sex and accessory sex tissues; viruses as causative agents for fowl tumors and rabbit papillomas; and possibility of relatively non-specific endogenous carcinogens. The publication also elaborates on attempts to control tumor induction and growth and the chemistry of tumors. The book is a vital reference for readers interested in the biochemistry of cancer.

Download or read book Molecular Carcinogenesis and the Molecular Biology of Human Cancer written by David Warshawsky and published by CRC Press. This book was released on 2005-10-31 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: To gain a complete overview of what is presently known about molecular carcinogenesis would prove to be a very daunting task for those not already steeped in this complex subject. Fortunately, David Warshawsky and Joseph Landolph Jr., both highly respected for their own contributions to the field, know exactly whom to call upon to fulfill the need

Download or read book Understanding Cancer written by David Tarin and published by Springer Nature. This book was released on 2023-02-02 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a unique, wide-ranging description of the phenomenon of cancer and its pathological effects in diverse species including humans, domesticated and wild animals, invertebrates, and plants. The broad scope of information presented is used to construct radical new insights into biological self-regulation and explain their relevance to its disruption by cancerous growth and spread within the human body. Mechanisms of action of carcinogenic agents, initiation, progression, metastasis, inappropriate gene expression, dormancy, latency, regression, and reasons for susceptibility and/or resistance to cancer are all considered. Also discussed are criteria for pathological diagnosis, advances in treatment, implications for public health, and pitfalls in diagnosis and interpretation of experimental results. The book describes operational mechanisms of cancer at the levels of whole individual, organ, tissue, cell, molecular, and even atomic (quantum) scales of structural and physiological order. Evidence is assembled from all these levels of organization to show that cancer is a dynamically changing disorder and that it is an inherent and perpetual risk of multicellular composition. This provides pragmatic new biological and clinical perspectives on malignant neoplasia. The biological insight is that it is a consequence of progressing miscommunication within a cellular society. The clinical perspective is realistic but optimistic in reasoning that, although cancer can never be completely eradicated from human life, because it is a disorder of our intrinsic biological constitution, it can be controlled and ameliorated and even cured in a proportion of individuals. The text is profusely illustrated with over 300 macroscopic and microscopic pictures. It will stimulate curiosity and interest specialists, as well as beginners, in many scientific disciplines and provides copious references to the medical and scientific literature supporting its conclusions. Readers from fields as diverse as medicine, pathology, veterinary sciences, cell biology, molecular biology, developmental biology, and epidemiology will find the information the book contains thought-provoking, interesting, and useful. Additionally, specialists in occupational and environmental health and legal experts focusing on exposure to carcinogenic materials and pollution will find the contents valuable and informative.

Download or read book Carcinogenesis written by Michael P Waalkes and published by CRC Press. This book was released on 1994-06-30 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carcinogens, like chemicals with other toxic hazards, often produce adverse effects only in specific organs or tissues. The factors determining whether a chemical induces cancer in an organ range from simple toxicokinetics to complex phenomena such as expression or lack of expression of specific genes.; This volume examines the site-specific factor

Download or read book Mechanisms of Carcinogenesis written by Elizabeth K. Weisburger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: but also the possibility of intervention in specific stages. In Human behavior, including stress and other factors, plays an important role in neoplasia, although too little is known addition, variables which affect cancer development as well on the reasons for such development. Carcinogens, which as some endogenous factors can be better delineated help initiate the neoplastic process, may be either synthetic through such investigations. The topics of this volume encompass premalignant non or naturally-occurring. Cancer causation may be ascribed to invasive lesions, species-specific aspects of carcinogenicity, certain chemicals, physical agents, radioactive materials, viruses, parasites, the genetic make-up of the organism, and radiation, viruses, a quantum theory of carinogenesis, onco bacteria. Humans, eumetazoan animals and vascular plants genes, and selected environmental carcinogens. are susceptible to the first six groups of cancer causes, whe reas the last group, bacteria, seems to affect only vascular plants. Neoplastic development may begin with impairment ofJmdy defenses by a toxic material (carcinogen) which acts as an initiator, followed by promotion and progression to an overt neoplastic state. Investigation of these processes Series Editor Volume Editor allows not only a better insight into the mechanism of action Hans E. Kaiser Elizabeth K. Weisburger vii ACKNOWLEDGEMENT Inspiration and encouragement for this wide ranging project on cancer distribution and dissemination from a comparative biological and clinical point of view, was given by my late friend E. H. Krokowski.

Download or read book The Biological Basis of Cancer written by Robert G. McKinnell and published by Cambridge University Press. This book was released on 2006-08-28 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a revised and updated edition of a text used in undergraduate courses on cancer biology. It covers everything from the molecular basis of cancer to clinical aspects of the subject, and has a lengthy bibliography designed to assist newcomers with the cancer literature. An introduction acquaints students with the biological principles of cancer and the human dimensions of the disease by considering genuine cases of cancer in fictionalized letters. Other chapters discuss cancer pathology, metastasis, carcinogenesis, genetics, oncogenes and tumor suppressors, epidemiology, and the biological basis of cancer treatment. Also included are an appendix with descriptions of common forms of cancer, a glossary of cancer-related terms and colour plates to illustrate the pathology of many of the types of cancer discussed in the text. Upper-division undergraduates with a background in freshman biology and chemistry, as well as beginning graduate students will find this a valuable text.

Download or read book Etiology Chemical and Physical Carcinogenesis written by Frederick F. Becker and published by Springer. This book was released on 1982-01-31 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: Band 1.

Download or read book A Synopsis of Cancer written by Wilfred Kark and published by Butterworth-Heinemann. This book was released on 2013-10-22 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Synopsis of Cancer: Genesis and Biology focuses on research into the genesis and biology of cancer, including origin of tumors, pathology and spread of cancer, and degenerative changes. The book first offers information on the nature of cancer and cancer spread, including degenerative changes, harmful effects, origin of tumors, direct and lymphatic spread, and non-vascular implantation spread. The text then takes a look at the general considerations and gastric cancer; geographical pathology of cancer in Africa; and geographical and occupational pathology of skin cancer. The publication ponders on religious customs, traditional practices, and social habits and occupational tumors of the urinary passages. Topics include clinical features, sites of tumors, link with spontaneous bladder cancer, carcinoma of the base of the tongue and the tonsils, and cancer of the penis. The manuscript also examines the cancer of the lungs, latency and cocarcinogenesis, and hormones and mammary cancer. The text is a dependable reference for readers interested in the study of cancer.

Download or read book Signaling Pathways in Squamous Cancer written by Adam B. Glick and published by Springer Science & Business Media. This book was released on 2010-11-25 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Squamous epithelia form the lining surface of tissues in contact with the environment: the skin, oral mucosa, esophagus and respiratory tract, the genital tract, and several other specialized tissues. These tissues are at highest risk for exposure to environmental carcinogens such as UV, tobacco smoke and infectious agents. Cancers that form in squamous epithelia are among the most common human solid tumors and have high morbidity and mortality. These cancers include squamous cell carcinoma of the skin, oral cancer, head and neck and esophageal cancer, certain lung cancers and cervical cancer. We propose to organize the book so that the early chapters will focus on individual pathways and more specific mechanisms in both normal function and cancer, while the later chapters will be more integrative and include overviews of biomarkers and therapeutic development. This should increase interest for clinically oriented researchers. All authors will be encouraged to provide a balanced review in addition to highlighting their own work.

Download or read book Contrary to Nature written by Michael Boris Shimkin and published by . This book was released on 1977 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Pathology The Big Picture written by William Kemp and published by McGraw Hill Professional. This book was released on 2007-08-22 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get the BIG PICTURE of Pathology - and focus on what you really need to know to score high on the course and board exam If you want a streamlined and definitive look at Pathology - one with just the right balance of information to give you the edge at exam time - turn to Pathology: The Big Picture. You'll find a succinct, user-friendly presentation especially designed to make even the most complex concept understandable in the shortest amount of study time possible. This perfect pictorial and textual overview of Pathology delivers: A “Big Picture” emphasis on what you must know verses “what's nice to know” Expert authorship by award-winning, active instructors Coverage of the full range of pathology topics - everything from cellular adaptations and injury to genetic disorders to inflammation to diseases of immunity Magnificent 4-color illustrations Numerous summary tables and figures for quick reference and rapid retention of even the most difficult topic Highlighted key concepts that underscore integral aspects of histology (key concepts are also listed in a table at the end of each chapter) USMLE-type questions, answers, and explanations to help you anticipate what you'll encounter on the exams And much more!