Download or read book Neoglycoconjugates Part A Synthesis written by and published by Academic Press. This book was released on 1994-11-22 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neoglycoconjugates are not only useful for the basic understanding of protein-carbohydrate interactions, but they have many practical applications as well. They are powerful reagents in many cell biology studies and excellent tools for the isolation and characterization of animal and plant lectins, separation of cells, as well as for the targeting of drugs, artificial vaccines, and diagnostic reagents. Volume 247 and its companion Volume 242 contain many practical methods on how to prepare and use neoglycoconjugates. Volume 242 deals with synthesis and 247 with biomedical applications.
Download or read book Neoglycoconjugates Pt A written by and published by . This book was released on 1994 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neoglycoconjugates Part A written by and published by . This book was released on 1994 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biophotonics Part A written by and published by Elsevier. This book was released on 2003-02-19 with total page 751 pages. Available in PDF, EPUB and Kindle. Book excerpt: The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today truly an essential publication for researchers in all fields of life sciences. * Discusses optical instrumentation for imaging, screening and diagnosis in molecules, tissues, and cells* Covers the development and application of optical probes and techniques for imaging and drug screening* Investigates the structure and dynamics of biomolecular systems, screening and drug discovery, and the diagnosis and treatment of disease
Download or read book Neoglycoconjugates written by Bozzano G Luisa and published by Academic Press. This book was released on 2012-12-02 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent decades, there has been an explosive growth in knowledge on the important biological roles of carbohydrates, especailly as specific information carriers. Neoglycoconjugates have been indispensable tools in these studies. This timely book, with both synthetic and application studies, will be of great value to researchers in a number of disciplines. Includes applications of neoglycoconjugates in medicine (vaccine preparation, drug targeting and tumor diagnosis) Is a comprehensive survey of synthetic strategies Covers application of neoglycoconjugates in basic research
Download or read book Sphingolipid Metabolism and Cell Signaling Part A written by and published by Elsevier. This book was released on 1999-11-01 with total page 786 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sphingolipids are found in all eukaryotic and in some prokaryotic organisms and provide structure for cell membranes, lipoproteins, and other biological materials as well as participate in the regulation of cell growth, differentiation, and diverse cell functions, including cell-cell communication, cell-substratum interactions, and intracellular signal transduction. This volume presents methods used in studying enzymes of sphingolipid biosynthesis and turnover, including inhibitors of some of these enzymes, genetic approaches, and organic and enzymatic syntheses of sphingolipids and analogs. Its companion Volume 312 will contain information on analyzing sphingolipids, sphingolipid transport and trafficking, and sphingolipid-protein interactions and cellular targets. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Download or read book Programmed Cell Death Part B written by Roya Khosravi-Far and published by Elsevier. This book was released on 2008-07-29 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the major goals of researchers in the field of apoptosis is to identify targets for novel therapies in cancer, AIDS, and Alzheimer’s disease. Understanding the molecular mechanisms of the various components of the apoptotic pathways is the first step to reaching this goal. The 2002 Nobel Prize in Physiology or Medicine was awarded to Sydney Brenner (United Kingdom), H. Robert Horvitz (US) and John E. Sulston (UK) "for their discoveries concerning genetic regulation of organ development and programmed cell death." Cell death is a fundamental aspect of embryonic development, normal cellular turnover and maintenance of homeostasis (maintaining a stable, constant environment) on the one hand, and aging and disease on the other. This volume addresses the significant advances with the techniques that are being used to analyze cell death. This volume provides the necessary, trusted methods to carry out this research on these latest therapeutic techniques. Once researchers understand the molecular mechanisms of the apoptotic pathways, they can begin to develop new therapies Presents key methods on studying tumors and how these cancer cells evade cell death Eliminates searching through many different sources to avoid pitfalls so the same mistakes are not made over and over
Download or read book Autophagy in Mammalian Systems Part B written by Daniel Klionsky and published by Academic Press. This book was released on 2009-03-05 with total page 571 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the companion volume to Daniel Klionsky’s Autophagy: Lower Eukaryotes, which features the basic methods in autophagy covering yeasts and alternative fungi (aspergillus, podospora, magnaporthe). Klionsky is one of the leading authorities in the field. He is the editor-in-chief of Autophagy. The November 2007 issue of Nature Reviews highlighted his article, “Autophagy: From phenomenology to molecular understanding in less than a decade. He is currently editing guidelines for the field, with 230 contributing authors, that will publish in Autophagy. Particularly in times of stress, like starvation and disease, higher organisms have an internal mechanism in their cells for chewing up and recycling parts of themselves. The process of internal “house cleaning in the cell is called autophagy – literally self-eating. Breakthroughs in understanding the molecular basis of autophagy came after the cloning of ATG1 (autophagy-related gene 1) in yeast. (To date, 30 additional yeast genes have been identified.) These ATG genes in yeast were the stepping stones to the explosion of research into the molecular analysis of autophagy in higher eukaryotes. In the future, this research will help to design clinical approaches that can turn on autophagy and halt tumor growth.
Download or read book Angiogenesis In Vivo Systems Part B written by and published by Academic Press. This book was released on 2009-02-12 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding how angiogenesis "works" and how to control it will have massive implications on the management, treatments, and ultimately the prevention of many common (and not so common) diseases. Angiogenesis is the growth of new blood vessels and is an important natural process in the body. A healthy body maintains a perfect balance of angiogenesis modulators. In many serious disease states, however, the body loses control over angiogenesis. Diseases that are angiogenesis-dependent result when blood vessels either grow excessively or insufficiently. Tried-and-tested techniques written by researchers that developed them, used them, and brought them to fruition Provides the "builder's manual" for essential techniques--a one-stop shop that eliminates needless searching among untested techniques Includes step-by-step methods for understanding the cell and molecular basis of wound healing, vascular integrin signaling, mechanical signaling in blood vessels, and vascular proteomics
Download or read book Small GTPases in Disease Part B written by and published by Academic Press. This book was released on 2008-04-01 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: The critically acclaimed laboratory standard for more than 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 400 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences. Methods in Enzymology is now available online at ScienceDirect — full-text online of volume 1 onward.
Download or read book Chromatin and Chromatin Remodeling Enzymes Part A written by Carl Wu and published by Elsevier. This book was released on 2004-02-20 with total page 579 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA in the nucleus of plant and animal cells is stored in the form of chromatin. Chromatin and the Chromatin remodellng enzymes play an important role in gene transcription. *Histone Bioinformatics *Biochemistry of histones, nucleosomes and chromatin *Molecular cytology of chromatin functions
Download or read book Vertebrate Phototransduction and the Visual Cycle Part A written by and published by Elsevier. This book was released on 2000-03-01 with total page 998 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, and its companion Volume 316, include newly developed methods to study vertebrate phototransduction and the visual cycle. Major topics covered include expression, isolation, and characterization of opsins; proteins that interact with rhodopsin; transducin and regulators of G-protein signaling; photoreceptor protein phosphatases, phosphodiesterase, and guanylylcyclase; cyclis nucleolide gated channels; Na+/Ca2+-K+ exchanges and ABCR transporter. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Download or read book RNA Ligand Interactions Part A Structural Biology Methods written by and published by Elsevier. This book was released on 2000-05-30 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA-Ligand Interactions, Part A focuses on structural biology methods. Major topics covered include semisynthetic methodologies (RNA synthetic methods and derivatization of RNA); RNA structure determination (X-ray crystallography, NMR, EM); techniques for monitoring RNA conformation and dynamics (solution methods and electrophoretic and spectroscopic methods); and modeling tertiary structure: Part B, its companion Volume 318 of Methods in Enzymology, focuses on molecular biology methods. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the Series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Download or read book DNA Microarrays Part A Array Platforms and Wet Bench Protocols written by and published by Elsevier. This book was released on 2011-08-19 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern DNA microarray technologies have evolved over the past 25 years to the point where it is now possible to take many million measurements from a single experiment. These two volumes, Parts A & B in the Methods in Enzymology series provide methods that will shepard any molecular biologist through the process of planning, performing, and publishing microarray results. Part A starts with an overview of a number of microarray platforms, both commercial and academically produced and includes wet bench protocols for performing traditional expression analysis and derivative techniques such as detection of transcription factor occupancy and chromatin status. Wet-bench protocols and troubleshooting techniques continue into Part B. These techniques are well rooted in traditional molecular biology and while they require traditional care, a researcher that can reproducibly generate beautiful Northern or Southern blots should have no difficulty generating beautiful array hybridizations. Data management is a more recent problem for most biologists. The bulk of Part B provides a range of techniques for data handling. This includes critical issues, from normalization within and between arrays, to uploading your results to the public repositories for array data, and how to integrate data from multiple sources. There are chapters in Part B for both the debutant and the expert bioinformatician. Provides an overview of platforms Includes experimental design and wet bench protocols Presents statistical and data analysis methods, array databases, data visualization and meta-analysis
Download or read book Recognition of Carbohydrates in Biological Systems Part A General Procedures written by Y. C. Lee and published by Elsevier. This book was released on 2003-09-15 with total page 667 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognition of carbohydrates in biological systems has been gaining more and more attention in recent years. Although methodology for studying recognition has been developing, there is no volume that covers the wide area of methodology of carbohydrate recognition. This volume, Recognition of Carbohydrates in Biological Systems, Part A: General Procedures, and its companion, Volume 363, present state-of-the-art methodologies, as well as the most recent biological observations in this area. Covers the isolation/synthesis of substances used in studying interactions involving carbohydrates Discussed the methodology for measuring such interactions Biological roles for such interactions are also covered
Download or read book Autophagy in Disease and Clinical Applications Part C written by Daniel Klionsky and published by Academic Press. This book was released on 2009-03-10 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third and final installment of Daniel J. Klionsky's new three-volume treatment of autophagy, this volume focuses on monitoring autophagy with regard to disease connections, and presents methods that can be used to analyze autophagy in clinical samples. Edited by one of the leading authorities in the field, this volume and its companion volumes, Autophagy: Lower Eukaryotes and Autophagy in Mammalian Systems, provide a comprehensive overview of the techniques involved in studying autophagy in eukaryotes and simple animal systems, mammalian cells and non-human animals, and humans. Particularly in times of stress, like starvation and disease, higher organisms have an internal mechanism in their cells for chewing up and recycling parts of themselves. The process of internal “house cleaning in the cell is called autophagy – literally self-eating. In the future, research in this field will help to design clinical approaches that can turn on autophagy and halt tumor growth. Provides an overview of autophagy in regards to humans, specifically regarding disease connections and clinical samples Includes methods to evaluate the role of autophagy in the drug-induced cell death of cancer cells in culture Presents reliable methods that, in this relatively new field, allow the reader to find appropriate techniques to identify, monitor, and quantify autophagic processes
Download or read book Protein Engineering for Therapeutics Part B written by and published by Academic Press. This book was released on 2012-01-25 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Methods in Enzymology looks at Protein Engineering for Therapeutics. The chapters provide an invaluable resource for academics, researchers and students alike. With an international board of authors, this volume is split into sections that cover subjects such as Peptides, and Scaffolds Chapters provide an invaluable resource for academics, researchers and students alike Iinternational board of authors This volume is split into sections that cover subjects such as peptides, and scaffolds
