Download or read book Neocortical Grafting to Newborn and Adult Rats written by Afsaneh Gaillard and published by . This book was released on 1998-05-20 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neocortical Grafting to Newborn and Adult Rats Developmental Anatomical and Functional Aspects written by Afsaneh Gaillard and published by Springer Science & Business Media. This book was released on 2013-03-12 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first experiments with neural transplantation into the brain (for a review, see Bjorklund and Stenevi 1985) were reported at the end of the last century by Thompson (1890), who took cortical tissue from adult cats and implanted the tissue pieces into the neocortex of adult dogs. The neurons did not survive, but the transplanted mass did not disintegrate entirely. Successful graft ing into the brain was reported later by Ranson (1909), who implanted spinal ganglia into the cerebral cortex of developing rats, and by Dunn (1917), who reported survival of implanted neonatal cortex into the cortex of newborn recipients. Another important step was made by Le Gros Clark (1940) who reported that, in the rabbit, embryonic (E) cortical tissue could be successfully grafted into the cortex of young recipients. Ex periments by Wallace and Das (1982), and Bjorklund and Stenevi (1984), showing behavioral effects of grafts, subsequently stimu lated a growing interest in neurotransplantation research. Intrac erebral grafting is now considered a powerful tool for addressing fundamental questions about development, regenerative, or re storative phenomena in the central nervous system (CNS) and is a potential therapy for neurodegenerative diseases.
Download or read book Neural Transplantation Methods written by Stephen B. Dunnett and published by Springer Science & Business Media. This book was released on 1999-10-20 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: we might seek alternative sources of donor tissues. Genetic en- neering, expansion of precursor cells, generation of immortalized cell lines, and transplantation between species are all under active investigation. Although significant difficulties remain for each of these alternatives, the problems appear soluble and relevant knowledge is expanding rapidly. As we enter the twenty-first century, the place of neural tra- plantation in experimental neuroscience is continuing to evolve. Rather than being a topic in its own right, neural transplantation increasingly serves as just another technique in the researcher's armory--alongside lesions, pharmaceuticals, gene transfer, and a variety of other techniques--for the experimental manipulation of brain structure and function. This is particularly true for studies of degeneration, plasticity, regeneration, and recovery of function in the nervous system, topics of increasing importance as experimental neurobiology is required to serve the higher needs of neurological and mental health in aging societies. Within this evolving context, Neural Transplantation Methods seeks to serve a particular need: to provide experimental neu- scientists with a source book of information to enable them to select and adapt transplantation techniques to their own expe- mental programs. All authors have been asked to address prac- cal issues, to enable the reader to assess what is available, what are the alternatives, what are the practical issues to be resolved in applying a particular protocol and getting it to work reliably in their unique experimental context.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1998 with total page 1646 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Dysfunction and Repair of Neural Circuits for Motor Control written by John Martin and published by Frontiers Media SA. This book was released on 2021-04-21 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book New Books in the Veterinary Medicine Library written by Ohio State University. Libraries. Veterinary Medicine Library and published by . This book was released on 1997 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book American Book Publishing Record Cumulative 1998 written by R R Bowker Publishing and published by . This book was released on 1999-03 with total page 1312 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Subject Guide to Books in Print written by and published by . This book was released on 2001 with total page 3054 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cumulated Index to the Books written by and published by . This book was released on 1999 with total page 1132 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 2003-08-22 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.
Download or read book The Neurobiology of Olfaction written by Anna Menini and published by CRC Press. This book was released on 2009-11-24 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Overview of Advances in OlfactionThe common belief is that human smell perception is much reduced compared with other mammals, so that whatever abilities are uncovered and investigated in animal research would have little significance for humans. However, new evidence from a variety of sources indicates this traditional view is likely
Download or read book Adult Neurogenesis written by Gerd Kempermann and published by Oxford University Press, USA. This book was released on 2006 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of adult neurogenesis and of stem cells in the brain has changed our view of the mature brain. Though we now know that the adult brain can make new neurons, it normally does so only in two privileged regions, the olfactory bulb and the hippocampus. Yet stem cells, which have the potential to produce new neurons, can be found throughout the adult brain. So why does the brain not make wider use of its potential for neurogenesis? And what is the function of new neurons and of neural stem cells in areas where they occur? After all, the brain regenerates poorly and many neurological and psychiatric disorders are chronic because cell replacement has not taken place. This is the first comprehensive, integrated account of one of the most exciting areas of neuroscience. It begins with the historical background and discusses theories of adult neurogenesis and neural stem cell biology in the context of learning and memory processes as well as structural plasticity. It describes in detail neurogenesis in the adult hippocampus and olfactory system and then surveys the regulatory, functional, and comparative aspects, concluding with a chapter on the provocative hypotheses that link failing adult neurogenesis with such diseases as temporal lobe epilepsy, major depression, brain tumors, and dementias. For graduate students, investigators, and clinicians in the neurosciences, developmental biology, and stem cell research, this book is a unique resource that sifts through the evidence for exciting scientific ideas and fosters a realistic view of the therapeutic possibilities for the use of stem cells in the adult brain.
Download or read book Vitamin A in Health and Disease written by Rune Blomhoff and published by CRC Press. This book was released on 1994-02-01 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviews the recent breakthroughs in vitamin A research. Discusses the metabolism of vitamin A; the mechanism of action of vitamin A and the provitamin A carotenoids; the role of retinoids in embryonic development, skin and epithelial cells, blood cells, vision, and reproduction; vitamin A deficiency and teratogenicity; and the anticancer role of vitamin A from an epidemiological point of view. Intended as a source of information for scientists engaged in research in the field of vitamin A.
Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2016-04-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Download or read book Cortical Development written by Ryoichiro Kageyama and published by Springer Science & Business Media. This book was released on 2013-09-30 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews recent progress in cortical development research, focusing on the mechanisms of neural stem cell regulation, neuronal diversity and connectivity formation, and neocortical organization. Development of the cerebral cortex, the center for higher brain functions such as cognition, memory, and decision making, is one of the major targets of current research. The cerebral cortex is divided into many areas, including motor, sensory, and visual cortices, each of which consists of six layers containing a variety of neurons with different activities and connections. As this book explains, such diversity in neuronal types and connections is generated at various levels. First, neural stem cells change their competency over time, giving sequential rise to distinct types of neurons and glial cells: initially deep layer neurons, then superficial layer neurons, and lastly astrocytes. The activities and connections of neurons are further modulated via interactions with other brain regions, such as the thalamocortical circuit, and via input from the environment. This book on cortical development is essential reading for students, postdocs, and neurobiologists.
Download or read book The Symbolic Species The Co evolution of Language and the Brain written by Terrence W. Deacon and published by W. W. Norton & Company. This book was released on 1998-04-17 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A work of enormous breadth, likely to pleasantly surprise both general readers and experts."—New York Times Book Review This revolutionary book provides fresh answers to long-standing questions of human origins and consciousness. Drawing on his breakthrough research in comparative neuroscience, Terrence Deacon offers a wealth of insights into the significance of symbolic thinking: from the co-evolutionary exchange between language and brains over two million years of hominid evolution to the ethical repercussions that followed man's newfound access to other people's thoughts and emotions. Informing these insights is a new understanding of how Darwinian processes underlie the brain's development and function as well as its evolution. In contrast to much contemporary neuroscience that treats the brain as no more or less than a computer, Deacon provides a new clarity of vision into the mechanism of mind. It injects a renewed sense of adventure into the experience of being human.
Download or read book Hippocampal Development written by S. J. Pleasure and published by S. Karger AG (Switzerland). This book was released on 2006 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hippocampal formation plays a critical role in navigation and memory under normal conditions. In pathologies such as Alzheimer's disease and epilepsy, the hippocampus represents one of the first brain regions to suffer damage. When hippocampal development is abnormal, pathological conditions featuring cognitive dysfunction and seizures are common, particularly in children. This publication summarizes new data and relevant findings to a critical understanding of hippocampal development - from anatomy to physiology and from rodents to human. It provides original articles on developmental pathology and on the ongoing role of developmental signaling systems in adults. Broadly, the topics include processes involved in the development of normal or abnormal hippocampus and pathological implications associated with normal or abnormal development, and neurogenesis in an immature or adult hippocampus. Presenting a wide-ranging collection of contributions on hippocampal development, this issue will be of great value for neurobiologists, neurologists, psychiatrists and pediatricians.
