Download or read book From Neurons to Neighborhoods written by National Research Council and published by National Academies Press. This book was released on 2000-11-13 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.

Download or read book Neuronal Dynamics written by Wulfram Gerstner and published by Cambridge University Press. This book was released on 2014-07-24 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: This solid introduction uses the principles of physics and the tools of mathematics to approach fundamental questions of neuroscience.

Download or read book Biophysics of Computation written by Christof Koch and published by Oxford University Press. This book was released on 2004-10-28 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural network research often builds on the fiction that neurons are simple linear threshold units, completely neglecting the highly dynamic and complex nature of synapses, dendrites, and voltage-dependent ionic currents. Biophysics of Computation: Information Processing in Single Neurons challenges this notion, using richly detailed experimental and theoretical findings from cellular biophysics to explain the repertoire of computational functions available to single neurons. The author shows how individual nerve cells can multiply, integrate, or delay synaptic inputs and how information can be encoded in the voltage across the membrane, in the intracellular calcium concentration, or in the timing of individual spikes.Key topics covered include the linear cable equation; cable theory as applied to passive dendritic trees and dendritic spines; chemical and electrical synapses and how to treat them from a computational point of view; nonlinear interactions of synaptic input in passive and active dendritic trees; the Hodgkin-Huxley model of action potential generation and propagation; phase space analysis; linking stochastic ionic channels to membrane-dependent currents; calcium and potassium currents and their role in information processing; the role of diffusion, buffering and binding of calcium, and other messenger systems in information processing and storage; short- and long-term models of synaptic plasticity; simplified models of single cells; stochastic aspects of neuronal firing; the nature of the neuronal code; and unconventional models of sub-cellular computation.Biophysics of Computation: Information Processing in Single Neurons serves as an ideal text for advanced undergraduate and graduate courses in cellular biophysics, computational neuroscience, and neural networks, and will appeal to students and professionals in neuroscience, electrical and computer engineering, and physics.

Download or read book New Directions in Child Abuse and Neglect Research written by National Research Council and published by National Academies Press. This book was released on 2014-03-25 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each year, child protective services receive reports of child abuse and neglect involving six million children, and many more go unreported. The long-term human and fiscal consequences of child abuse and neglect are not relegated to the victims themselves-they also impact their families, future relationships, and society. In 1993, the National Research Council (NRC) issued the report, Under-standing Child Abuse and Neglect, which provided an overview of the research on child abuse and neglect. New Directions in Child Abuse and Neglect Research updates the 1993 report and provides new recommendations to respond to this public health challenge. According to this report, while there has been great progress in child abuse and neglect research, a coordinated, national research infrastructure with high-level federal support needs to be established and implemented immediately. New Directions in Child Abuse and Neglect Research recommends an actionable framework to guide and support future child abuse and neglect research. This report calls for a comprehensive, multidisciplinary approach to child abuse and neglect research that examines factors related to both children and adults across physical, mental, and behavioral health domains-including those in child welfare, economic support, criminal justice, education, and health care systems-and assesses the needs of a variety of subpopulations. It should also clarify the causal pathways related to child abuse and neglect and, more importantly, assess efforts to interrupt these pathways. New Directions in Child Abuse and Neglect Research identifies four areas to look to in developing a coordinated research enterprise: a national strategic plan, a national surveillance system, a new generation of researchers, and changes in the federal and state programmatic and policy response.

Download or read book Axons and Brain Architecture written by Kathleen Rockland and published by Academic Press. This book was released on 2015-12-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Several excellent monographs exist which deal with axons. These, however, focus either on the cellular and molecular biology of axons proper or on network organization of connections, the latter with only an incidental or abstract reference to axons per se. Still relatively neglected, however, is the middle ground of terminations and trajectories of single axons in the mammalian central nervous system. This middle level of connectivity, between networks on the one hand and local, in vitro investigations on the other, is to some extent represented by retrograde tracer studies and labeled neurons, but there have so far been many fewer of the complementary anterograde studies, with total visualization of the axonal arborization. The present volume brings together in one source an interrelated treatment of single axons from the perspective of microcircuitry and as substrates of larger scale organization (tractography). Especially for the former area - axons in microcircuitry - an abundance of published data exists, but these are typically in specialty journals that are not often accessed by the broader community. By highlighting and unifying the span from microcircuitry to tractography, the proposed volume serves as a convenient reference source and in addition inspires further interactions between what currently tend to be separate communities. The volume also redresses the imbalance between in vitro/local connectivity and long-distance connections. Focusing on mammalian systems, Part 1 of this book is devoted to anatomical investigations of connections at the single axon level, drawing on modern techniques and classical methods from the 1990s. A particular emphasis is on broad coverage of cortical and subcortical connections from different species, so that common patterns of divergence, convergence, and collateralization can be easily appreciated. Part 2 addresses mechanisms of axon guidance, as these seem particularly relevant to pathways and branching patterns. Part 3 covers axon dynamics and functional aspects; and Part 4 focuses on tractography, notably including comparisons between histological substrates and imaging.

Download or read book Central Nervous System Diseases written by Dwaine F. Emerich and published by Springer Science & Business Media. This book was released on 1999-11-24 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prominent experimentalists critically review the animal models widely used in developing powerful new therapies for central nervous system diseases. Coverage includes novel uses of animal models of Alzheimer's, Parkinson's, and Huntington's diseases, and studies of aging. Techniques that rely heavily on behavioral analyses, as well as models developed from infusions of neurotoxins and from advances in molecular biology, are thoroughly explicated, as are models developed for more acute neurological conditions, including traumatic brain injury and stroke. Comprehensive and authoritative, Central Nervous System Diseases: Innovative Animal Models from Lab to Clinic offers neuroscientists, pharmacologists, and interested clinicians a unique survey of the most productive animal models of the leading neurological diseases currently employed to develop today's innovative drug therapies.

Download or read book The Cognitive and Neural Bases of Spatial Neglect written by Hans-Otto Karnath and published by . This book was released on 2002 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spatial neglect is a disorder of space-related behaviour. It is characterized by failure to explore the side of space contralateral to a brain lesion, or to react or respond to stimuli or subjects located on this side. Research on spatial neglect and related disorders has developed rapidly in recent years. These advances have been made as a result of neuropsychological studies of patients with brain damage, behavioural studies of animal models, as well as through functional neurophysiological experiments and functional neuroimaging. The Cognitive and Neural Bases of Spatial Neglect provides an overview of this wide-ranging field of scientific endeavour, providing a cohesive synthesis of the most recent observations and results. As well as being a fascinating clinical phenomenon, the study of spatial neglect helps us to understand normal mechanisms of directing and maintaining spatial attention and is relevant to the contemporary search for the cerebral correlates of conscious experience, voluntary action and the nature of personal identity itself. The book is divided into seven sections covering the anatomical and neurophysiological bases of the disorder, frameworks of neglect, perceptual and motor factors, the relation to attention, the cognitive processes involved, and strategies for rehabilitation. Chapters have been written by a team of the leading international experts in this field. This will be essential reading for neuropsychologists, neurologists, neurophysiologists, cognitive neuroscientists and psychologists.

Download or read book Unilateral Neglect written by John Marshall and published by Psychology Press. This book was released on 2013-04-15 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unilateral neglect is a fairly common disorder, usually associated with a stroke, which results in a neglect or lack of attention to one side of space usually, but not exclusively, the left. Theoretically, it is one of the most interesting and important areas in neuropsychology; practically, it is one of the greatest therapeutic problems facing therapists and rehabilitationists. This book covers all aspects of the disorder, from an historical survey of research to date, through the nature and anatomical bases of neglect, and on to review contemporary theories on the subject. The final section covers behavioural and physical remediation. A greater understanding of unilateral neglect will have important implications not just for this particular disorder but for the understanding of brain function as a whole.

Download or read book Neurophysiological and Neuropsychological Aspects of Spatial Neglect written by M. Jeannerod and published by Elsevier. This book was released on 1987-03-01 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spatial Neglect is one of the few areas in Neuropsychology where clinicians, psychologists and animal experimenters have succeeded in adopting a common language. The result of interaction between these three approaches has been some important new advances, which are presented in this volume.Apart from its clinical significance in neuropsychology, Spatial Neglect raises important questions in the field of behavioral neurosciences. In this volume, three aspects are examined: a) normal subjects, where new findings on spatial behavior are described. b) brain-lesioned subjects, where the classical studies on neglect are reconsidered in the light of new findings. c) animals, where new experimental situations allow a deeper understanding of the neural substrate.

Download or read book Updates on multisensory perception from neurons to cognition written by Angelo Maravita and published by Frontiers E-books. This book was released on with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years there has been a dramatic progress in understanding how stimuli from different sensory modalities are integrated among each other. Multisensory integration results in a unitary representation of the world that strongly characterizes perception and cognition in humans. Knowledge about multi sensory integration has research techniques and approaches, including neurophysiology, experimental psychology, neuropsychology, neuroimaging, and computational modelling. This special issue aims at presenting an up-to-date integrative overview of the physiological, psychological, developmental, and functional processes associated with multisensory integration. The proposed collection of papers is organized thematically into sections, each featuring a state-of-the-art review of key themes in multisensory research, from more approaches in the animal, to the study of multisensory perception and cognition in humans. Specifically, this special issue will consider: The physiological mechanisms of multisensory processing in cortical and subcortical brain structures of model animal species, (rat, cat, and monkey); current biologically inspired computational modelling of multisensory integration; evidence about the multisensory contributions to perception in humans, as highlighted by psychophysical and neuropsychological evidence; the neural basis of multisensory processing in the human brain uncovered by recent neuroimaging techniques, including EEG, PET, fMRI; the consequences of the breakdown of normal sensory integration as shown by studies with techniques of brain stimulation in humans; developmental processes of multisensory perception in humans and the constrains for the emergence of multisensory processes in relation to sensory experience; the issue of crossmodal neuroplasticity concerning behavioral and neural changes following sensory deprivation. The challenge of this Research Topic is to provide an interdisciplinary context allowing to understand the basic principles of multisensory integration in humans and the key issues that this fascinating field of study rises for future research.

Download or read book Cilia and Nervous System Development and Function written by Kerry L. Tucker and published by Springer Science & Business Media. This book was released on 2013-01-19 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cilia are tiny microtubule-based organelles projecting from the plasma membrane of practically all cells in the body. In the past 10 years a flurry of research has indicated a crucial role of this long-neglected organelle in the development and function of the central nervous system. A common theme of these studies is the critical dependency of signal transduction of the Sonic hedgehog, and more recently, Wnt signaling pathways upon cilia to regulate fate decisions and morphogenesis. Both primary and motile cilia also play crucial roles in the function of the nervous system, including the primary processing of sensory information, the control of body mass, and higher functions such as behavior and cognition, serving as "antennae" for neurons to sense and process their environment. In this book we describe the structure and function of cilia and the various tissues throughout the brain and spinal cord that are dependent upon cilia for their proper development and function.

Download or read book Child Abuse and Neglect written by Carole Jenny and published by Elsevier Health Sciences. This book was released on 2010-09-15 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carole Jenny's Child Abuse and Neglect: Diagnosis, Treatment and Evidence focuses attention on the clinical evidence of child abuse to help you correctly diagnose and treat such cases in your own practice. In print and online, this unique, well-illustrated clinical reference provides new insights into the presentation and differential diagnosis of physical abuse and looks at shaken baby syndrome, sex offenders, and abuse in religious organizations, information on the biomechanics of injury, and other factors. Identify an abusive injury and treat it effectively by reviewing evidence and critical analyses from leading authorities in the field. Recognize the signs of shaken baby syndrome, sex offenders, and abuse in religious organizations. Understand the biomechanics of injury to determine whether abuse was truly the cause of a child's injury. View illustrations that show first-hand examples of child abuse or neglect. Search the complete contents online and download the illustrations at www.expertconsult.com.

Download or read book Binocular rivalry a gateway to consciousness written by Alexander Maier and published by Frontiers E-books. This book was released on with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain-mind problems like consciousness have been stimulating the interest of philosophers and scientists since the ancient times. In the last decades, the dramatic development of neuroscience has allowed studying such phenomena at several different levels – from single neurons to behavior. Binocular rivalry, a paradigm dissociating the sensory input from the conscious perception during dichoptic viewing of incongruent images, has been a celebrated example of such a tool. During the last century, empirical research on binocular rivalry contributed the first important insights into the neuronal mechanisms of subjective visual perception. Recent advances in brain imaging and electrophysiological recording/stimulating techniques as well as novel theoretical concepts and analytical methods could be exploited to expand our knowledge on this fascinating phenomenon of visual perception and elucidate the neural processes underlying visual consciousness. This Research Topic aims to bring together contributions that could expand the current frontiers of knowledge in binocular rivalry. In particular we would like to focus on reviews, hypothesis & theory or original research articles that specifically combine novel concepts, analytical tools and neurophysiological techniques with binocular rivalry. We expect that these contributions will a) integrate the vast knowledge already existing in the field b) formulate and, when possible, address questions under the light of recent methodological advances in neuroscience and c) provide a benchmark that will stimulate future cutting edge research.

Download or read book Nurturing Natures written by Graham Music and published by Psychology Press. This book was released on 2016-10-21 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition of the bestselling text, Nurturing Natures, provides an indispensable synthesis of the latest scientific knowledge about children’s emotional development. Integrating a wealth of both up-to-date and classical research from areas such as attachment theory, neuroscience developmental psychology and cross-cultural studies, it weaves these into an accessible enjoyable text which always keeps in mind children recognisable to academics, practitioners and parents. It unpacks the most significant influences on the developing child, including the family and social context. It looks at key developmental stages from life in the womb to the pre-school years and right up until adolescence, covering important topics such as genes and environment, trauma, neglect or resilience. It also examines how children develop language, play and memory and, new to this edition, moral and prosocial capacities. Issues of nature and nurture are addressed and the effects of different kinds of early experiences are unpicked, creating a coherent and balanced view of the developing child in context. Nurturing Natures is written by an experienced child therapist who has used a wide array of research from different disciplines to create a highly readable and scientifically trustworthy text. This book should be essential reading for childcare students, for teachers, social workers, health visitors, early years practitioners and those training or working in child counselling, psychiatry and mental health. Full of fascinating findings, it provides answers to many of the questions people really want to ask about the human journey from conception into adulthood. .

Download or read book The Cognitive Neuroscience of Consciousness written by Stanislas Dehaene and published by MIT Press. This book was released on 2001 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Empirical and theoretical foundations of a cognitive neuroscience of consciousness.

Download or read book Principles of Behavioral and Cognitive Neurology written by M.-Marsel Mesulam and published by Oxford University Press. This book was released on 2000-01-27 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thoroughly revised new edition of a classic book provides a clinically inspired but scientifically guided approach to the biological foundations of human mental function in health and disease. It includes authoritative coverage of all the major areas related to behavioral neurology, neuropsychology, and neuropsychiatry. Each chapter, written by a world-renowned expert in the relevant area, provides an introductory background as well as an up-to-date review of the most recent developments. Clinical relevance is emphasized but is placed in the context of cognitive neuroscience, basic neuroscience, and functional imaging. Major cognitive domains such as frontal lobe function, attention and neglect, memory, language, prosody, complex visual processing, and object identification are reviewed in detail. A comprehensive chapter on behavioral neuroanatomy provides a background for brain-behavior interactions in the cerebral cortex, limbic system, basal ganglia, thalamus, and cerebullum. Chapters on temperolimbic epilepsy, major psychiatric syndromes, and dementia provide in-depth analyses of these neurobehavioral entities and their neurobiological coordinates. Changes for this second edition include the reflection throughout the book of the new and flourishing alliance of behavioral neurology, neuropsychology, and neuropsychiatry with cognitive science;major revision of all chapters; new authorship of those on language and memory; and the inclusion of entirely new chapters on psychiatric syndromes and the dementias. Both as a textbook and a reference work, the second edition of Principles of Behavioral and Cognitive Neurology represents an invaluable resource for behavioral neurologists, neuropsychologists, neuropsychiatrists, cognitive and basic neuroscientists, geriatricians, physiatrists, and their students and trainees.

Download or read book The Root of Thought written by Andrew Koob and published by FT Press. This book was released on 2009-06-03 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Until recently, neuroscientists thought glial cells did little more than hold your brain together. But in the past few years, they've discovered that glial cells are extraordinarily important. In fact, they may hold the key to understanding intelligence, treating psychiatric disorders and brain injuries and perhaps even curing fatal conditions like Alzheimer's, Parkinson's, and Lou Gehrig's Disease. In The Root of Thought, leading neuroscientist Dr. Andrew Koob reveals what we've learned about these remarkable cells, from their unexpected role in information storage to their function as adult stem cells that can keep your brain growing and adapting longer than scientists ever imagined possible. Ranging from fruit flies to Einstein, Koob reveals the surprising correlation between intelligence and the brain's percentage of glial cells - and why these cells' unique wavelike communications may be especially conducive to the fluid information processing human beings depend upon. You'll learn how crucial glial cells grow and develop... why almost all brain tumors are comprised of glial cells and the potential implications for treatment... even the apparent role of glial cells in your every thought and dream!