Download or read book Negative Symptom and Cognitive Deficit Treatment Response in Schizophrenia written by Richard S. E. Keefe and published by American Psychiatric Pub. This book was released on 2008-11-01 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the first time in a single volume, distinguished experts address the complex issues -- issues rarely confronted in empirical studies of patients with schizophrenia -- and controversial research surrounding the assessment of negative symptoms and cognitive deficits in patients with schizophrenia. Despite recent advances in our understanding of schizophrenia, still notably absent is consensus in assessing negative symptom treatment response. What is the most effective assessment method -- given the varying methodologies and contradictory results to date? What constitutes an adequate response? Which medication -- none is specifically indicated and licensed for negative symptom treatment -- yields the best results? What are the indications for use of this medication? Which instrument best measures negative symptom treatment response (eight rating scales are analyzed here)? Reaching consensus among clinicians and researchers alike is even more difficult because assessment is often thwarted by extrapyramidal side effects of medications, similarities to depressive symptoms, and secondary effects of psychotic experiences. In addition to clarifying these pressing issues, Negative Symptom and Cognitive Deficit Treatment Response in Schizophrenia also discusses The importance of measuring the experience of emotion versus the more traditional objectively measured symptoms in patients with schizophrenia, and how deficits in emotional experience may resist treatment -- even in treatment-responsive patients. The family as an often overlooked source of information about negative symptom improvement or worsening, and the impact of negative symptoms on patients' relatives. How treatment affects social functioning and subjective experience of "quality of life," and the importance of neurocognitive dysfunction in the social deficits of schizophrenia, which often persist despite significant amelioration of other symptoms. Specific guidelines for assessing neurocognitive treatment response. Cognitive enhancement is a major factor in improving the quality of patients' lives. The latest research on the neurobiology of negative symptoms, including the role of various neurotransmitter systems and brain regions in mediating negative symptom pathology. Also discussed is single vs. multiple pathophysiological processes and single treatment modality vs. distinct treatments for different aspects of negative symptoms. How to distinguish "pure" negative symptoms from deficit symptoms (i.e., those that persist for at least 1 year and are not secondary to factors such as depression, medication side effects, anxiety, delusions, and hallucinations), and which treatment is indicated for each. Highlighted by patient vignettes, this in-depth guide will be welcomed by all clinicians who treat patients with schizophrenia and want to know and document whether their interventions ameliorate negative symptoms and cognitive dysfunction, and by all researchers who study schizophrenia, particularly those interested in clinical issues and treatment studies.
Download or read book Cognitive Impairment in Schizophrenia written by Philip D. Harvey and published by Cambridge University Press. This book was released on 2013-01-24 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides state-of-the-art information about cognition in schizophrenia with a wide ranging focus on measuring and treating cognitive deficits.
Download or read book Managing Negative Symptoms of Schizophrenia written by István Bitter and published by Oxford University Press. This book was released on 2020-04-09 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Schizophrenia is one of the most severe psychiatric disorders, carrying with it significant stigma and a number of debilitating symptoms. While material on its "positive" symptoms, such as hallucinations and delusions, is readily available, its "negative" symptoms, which present heterogeneously as deficits across a variety of domains, are not nearly so well-documented and often go undiagnosed with no effective treatment. Given the poor functioning and outcomes which occur as a result of these symptoms, it is imperative they receive greater focus. Part of the Oxford Psychiatry Library (OPL) series, this concise pocketbook provides readers with a comprehensive overview of the definition, evaluation, and treatment of negative symptoms. Written by experts in the field, with key points at the beginning of each chapter for quick reference, this is an invaluable resource for any mental health care professional working with individuals affected by schizophrenia.
Download or read book Cognitive Enhancement in Schizophrenia and Related Disorders written by Matcheri Keshavan and published by Cambridge University Press. This book was released on 2019-03-21 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical guide on how to assess and treat schizophrenia and related disorders using cognitive rehabilitation.
Download or read book Cognition in Schizophrenia written by Tonmoy Sharma and published by . This book was released on 2000 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although it has been known for 100 years that cognitive functioning is impaired in schizophrenia, the implications of this impairment have only recently been clearly understood. While in the past, cognitive deficits were thought to be the result of other aspects of the illness, such as poor co-operation, or as a result of the treatment of the illness, it is now known that these factors exert only a very minor influence on cognitive deficit. This book, with contributions from the major international names in the field, reviews the most recent research on the impairment of cognitive functioning in schizophrenia, covering: what it is, how wide-ranging it can be, what the clinical implications are, and how it can be treated? A detailed insight into cognitive deficit is the key to understanding why previous treatments have failed, and the key by which new treatments may change this terrible illness, treatments significantly more effective than earlier interventions.
Download or read book Novel Antischizophrenia Treatments written by Mark A. Geyer and published by Springer Science & Business Media. This book was released on 2012-10-01 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume tries to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume concentrates on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.
Download or read book Clinical Manual for Treatment of Schizophrenia written by John Lauriello and published by American Psychiatric Pub. This book was released on 2012-09-24 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Clinical Manual for the Treatment of Schizophrenia provides a wide-ranging, empirically based review of assessment and treatment issues in schizophrenia, offered from a multicultural and supremely patient-centered perspective. The following features reflect the care taken in developing this manual, as well as the inclusive nature of the contents: The initial chapter offers a thorough introduction to the disease -- its history, etiology, epidemiology, risk factors, and social aspects -- seen through the lens of a case study. The chapter ends with an overview of the diagnostic process, allowing the reader to place what follows into context. The basic science underlying schizophrenia is explained next, with coverage of biological markers; brain structure, function, and cytology; the dopamine and glutamate hypotheses; and the neurodevelopmental model of the disease. The chapter on clinical assessment focuses on making the differential diagnosis according to established criteria, with emphasis on a person-oriented approach that takes into account early trauma, stressful events, and the subjective well-being of the patient. Subsequent chapters explore cognition, comorbidity, substance abuse, and treatment-resistant symptoms in schizophrenia. Finally, chapters on the pharmacological and psychosocial treatment of schizophrenia compare and contrast these approaches, ensuring that the reader is completely up-to-date and knowledgeable about available treatment options. Clinicians who work with schizophrenic patients in a variety of settings -- from private practice to emergency departments -- will benefit from the scholarship and experience of this manual's astute and insightful authors.
Download or read book Negative symptoms and cognitive impairment in schizophrenia spectrum disorders written by Armida Mucci and published by Frontiers Media SA. This book was released on 2023-01-11 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Schizophrenia in the 21st Century written by T.H.J. Burne and published by BoD – Books on Demand. This book was released on 2012-03-23 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Schizophrenia is a poorly understood but very disabling group of brain disorders. While hallucinations and delusions (positive symptoms of schizophrenia) feature prominently in diagnostic criteria, impairments of memory and attentional processing (cognitive symptoms of schizophrenia) are attracting increasing interest in modern neuropsychiatry. Schizophrenia in the 21st Century brings together recent findings on this group of devastating disorders. We are still a long way from having effective treatment options, particularly for cognitive symptoms, and lack effective interventions and ways to prevent this disease. This volume covers various current options for therapy, clinical research into cognitive symptoms of schizophrenia and preclinical research in animal models.
Download or read book Schizophrenia Bulletin written by and published by . This book was released on 1992 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Oxford Textbook of Cognitive Neurology and Dementia written by Masud Husain and published by Oxford University Press. This book was released on 2018-10-29 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers the dramatic developments that have occurred in basic neuroscience and clinical research in cognitive neurology and dementia. It is based on the clinical approach to the patient, and provides essential knowledge that is fundamental to clinical practice.
Download or read book Understanding and Caring for People with Schizophrenia written by Ragy R. Girgis and published by Routledge. This book was released on 2020-10-29 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book challenges professional and public misconceptions of schizophrenia as an illness with intractable symptoms and inexorable mental deterioration, educating clinicians and researchers on the effectiveness of treatment to change the course of or prevent the onset of illness. The authors illustrate such effectiveness through fifteen case studies examining psychosis in diverse clients. These case studies are divided into the three phases of the illness—prodromal/clinical high risk, first-episode, chronic, and treatment-refractory—with accompanying analyses of the causes, symptoms, interventions and treatments. By depicting patients at different clinical stages of the illness, with accompanying explanations of how they got to that point, what might have been done to avoid – or has been done to achieve – this outcome, the reader will gain an appreciation of the nature of the illness and for the therapeutic potential of currently available treatments. Readers will learn about the various clinical aspects of schizophrenia and treatment including diagnosis, prognosis, clinical presentation, suicide risk, cognitive deficits, stigma, medication management, and psychosocial interventions.
Download or read book The Epidemiology of Schizophrenia written by Robin M. Murray and published by Cambridge University Press. This book was released on 2009-10-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: An international team of leading researchers and clinicians provides the first comprehensive, epidemiological overview of this multi-faceted and still-perplexing disorder. Controversial issues such as the validity of discrete or dimensional classifications of schizophrenia and the continuum between psychosis and 'normality' are explored in depth. Separate chapters are devoted to topics of particular relevance to schizophrenia such as suicide, violence and substance abuse. Finally, new prospects for treatment and prevention are considered.
Download or read book Therapy Resistant Schizophrenia written by H. Elkis and published by Karger Medical and Scientific Publishers. This book was released on 2010-07-29 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: The psychotic symptoms of up to 30% of schizophrenic patients do not respond adequately to treatment with antipsychotic drugs, other than clozapine. These refractory patients are generally among the most disabled of all people with schizophrenia and require special assessment and treatment. This volume presents the latest research and recommendations on the definition, causes and therapy of treatment-resistant schizophrenia (TRS). Methods for identification and optimal management of TRS are reviewed. Clozapine and other atypical antipsychotic drugs which are the primary treatment for TRS, as well as non-pharmacologic treatments such as transcranial magnetic stimulation, cognitive behavior therapy and ECT are discussed in depth. Potential causative factors and identifying features such as genetic factors, poor premorbid functioning, longer duration of untreated psychosis, and biological measures such as structural and functional brain abnormalities are also reviewed in depth in the present volume.
Download or read book Negative Versus Positive Schizophrenia written by Andreas Marneros and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: The positive versus negative distinction of schizophrenic disorders has pro moted ongoing research. Phenomenology, psychopathology, biology, genet ics, pharmacological and nonpharmacological treatment, psychosocial and longitudinal research: all have found a new focus of interest. This volume attempts to provide an unbiased picture of the status of American and Eu ropean knowledge regarding the positive/negative distinction. Researchers from North America and Europe describe the relation of modern concepts of positive and negative symptomatology to the original models of Rey nolds and Jackson. Integrating phenomenological, genetic, and biological factors, the authors depict current methods of assessing positive and nega tive symptomatology, differentiating between primary and secondary symp tomatology, and using pharmacological and nonpharmacological treatment. The stability of positive and negative symptoms over time and evidence for the occurrence of separate positive and negative episodes over a long-term course of schizophrenia are extensively discussed in terms of their implica tions on the positive/negative construct. The relevance of the positive/nega tive dichotomy to child and adolescent schizophrenia is also debated. The main aim of this book is not to advocate a single concept and present only arguments supporting it, but to discuss important controversies. Prob lems concerning a concept cannot be solved by ignoring them. However, unanswered questions may be resolved through discussion, debate, and con structive compromise.
Download or read book Cognitive Impairment in Schizophrenia written by Philip D. Harvey and published by Cambridge University Press. This book was released on 2013-01-24 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although the precise mechanisms and pathways of schizophrenia remain something of a mystery, there is little dispute that cognitive deficits present as some of the clearest and most debilitating symptoms of the disease. This book describes the characteristics of cognitive deficits in schizophrenia, functional implications, the course of impairments, the genetic and biological contributions and reviews management options, including neuropsychological, psychological and pharmacological techniques. Chapters are written by leading experts in the field, in an accessible and highly informative style, ensuring the content is clinically relevant. State-of-the-art information about new developments in the treatment of related features of the illness, such as disability, is provided. The wide ranging focus of this volume will appeal to clinicians and academic researchers working with patients impaired by severe mental illness.
Download or read book Schizophrenia Research Trends written by Konstance V. Almann and published by Nova Publishers. This book was released on 2007 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Schizophrenia is a chronic, severe, and disabling psychosis, which is an impairment of thinking in which the interpretation of reality is abnormal. Psychosis is a symptom of a disordered brain. Approximately One percent of the population worldwide develops schizophrenia during their lifetime. Although schizophrenia affects men and women with equal frequency, the disorder often appears earlier in men, usually in the late teens or early twenties, than in women, who are generally affected in the twenties to early thirties. People with schizophrenia often suffer symptoms such as hearing internal voices not heard by others, or believing that other people are reading their minds, controlling their thoughts, or plotting to harm them. The current evidence concerning the causes of schizophrenia are many. It is quite clear that multiple factors are involved. These include changes in the chemistry of the brain, changes in the structure of the brain, and genetic factors. Viral infections and head injuries may also play a role. New molecular tools and modern statistical analyses allow focusing in on particular genes that might make people more susceptible to schizophrenia by affecting, for example, brain development or neurotransmitter systems governing brain functioning. State-of-the-art imaging techniques are being used to study the living brain. They have recently revealed specific, subtle abnormalities in the structure and function of the brains of patients with schizophrenia. In other imaging studies, early biochemical changes that may precede the onset of disease symptoms have been noted, prompting examination of the neural circuits that are most likely to be involved in producing those symptoms. This book presents new and important research in the field.
