Download or read book Need to know about the 5 Most Common Ashkenazi Genetic Diseases A Concise Review written by Dr. Hakim. Saboowala. and published by Dr.Hakim Saboowala. This book was released on with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: Need to know about the 5 Most Common Ashkenazi Genetic Diseases. A Concise Review. Ashkenazi Jewish genetic diseases are a group of quaint disorders that occur more often in people of Eastern European (Ashkenazi) Jewish heritage than in the general population. Even though most of these diseases are severe and can cause early death, some can be treated to reduce symptoms and prolong life. Some of these diseases can be found during pregnancy through: · Chorionic villus sampling (CVS) or · Amniocentesis. This testing is done usually if one or both parents are carriers of a genetic disease. Diseases in this group include the followings but it is preferred to discus 5 most common Disorders below concisely: · Bloom syndrome. · Canavan disease · Cystic fibrosis.* · Familial dysautonomia (FD).* · Fanconi anemia. · Spinal Muscular Atroph.* · Gaucher disease.* · Mucolipidosis IV. · Niemann-Pick disease (type A). · Tay-Sachs disease.* · Torsion dystonia. About 1 out of 4 people of Ashkenazi Jewish heritage is a carrier of one of these genetic conditions. Thus, an attempt has been made in this E-Booklet to present the following, only 5 most common Disorders concisely for enthusiastic medicos along with relevant Illustrations for better understanding. 1. Gaucher Disease* 2. Cystic Fibrosis* 3. Tay-Sachs Disease* 4. Familial Dysautonomia* 5. Spinal Muscular Atrophy* …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H. (London)
Download or read book Risky Genes written by Jessica Mozersky and published by Routledge. This book was released on 2013 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: What does it mean to be told you have an increased risk of genetic breast cancer because you are of Ashkenazi Jewish origin? In a time of ever increasing knowledge about variations in genetic disease risk among different populations, there is a pressing need for research regarding the implications of such information for members of high-risk populations. With first hand, intimate descriptions of women's experiences of being Jewish and of being at increased risk of genetic breast cancer, this book offers new insight into the ongoing debates regarding the implications of genetic research for populations, and of new genetic knowledge for individual and collective identity.
Download or read book Breast Cancer Gene Research and Medical Practices written by Sahra Gibbon and published by Routledge. This book was released on 2014-03-05 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of the two inherited susceptibility genes BRCA1 and BRCA2 in the mid-1990s created the possibility of predictive genetic testing and led to the establishment of specific medical programmes for those at high risk of developing breast cancer in the UK, US and Europe. The book provides a coherent structure for examining the diversity of practices and discourses that surround developments linked to BRCA genetics, and to the evolving field of genetics more broadly. It will be of interest to students and scholars of anthropology, sociology, history of science, STS, public health and bioethics. Chapter 8 of this book is freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND) 3.0 license.
Download or read book Assessing Genetic Risks written by Institute of Medicine and published by National Academies Press. This book was released on 1994-01-01 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Raising hopes for disease treatment and prevention, but also the specter of discrimination and "designer genes," genetic testing is potentially one of the most socially explosive developments of our time. This book presents a current assessment of this rapidly evolving field, offering principles for actions and research and recommendations on key issues in genetic testing and screening. Advantages of early genetic knowledge are balanced with issues associated with such knowledge: availability of treatment, privacy and discrimination, personal decision-making, public health objectives, cost, and more. Among the important issues covered: Quality control in genetic testing. Appropriate roles for public agencies, private health practitioners, and laboratories. Value-neutral education and counseling for persons considering testing. Use of test results in insurance, employment, and other settings.
Download or read book Heredity and Hope written by Ruth Schwartz COWAN and published by Harvard University Press. This book was released on 2009-06-30 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neither minimizing the difficulty of the choices that modern genetics has created for us nor fearing them, Cowan argues that we can improve the quality of our own lives and the lives of our children by using the modern science and technology of genetic screening responsibly.
Download or read book Legacy written by Harry Ostrer MD and published by Oxford University Press. This book was released on 2012-08-10 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Who are the Jews--a race, a people, a religious group? For over a century, non-Jews and Jews alike have tried to identify who they were--first applying the methods of physical anthropology and more recently of population genetics. In Legacy, Harry Ostrer, a medical geneticist and authority on the genetics of the Jewish people, explores not only the history of these efforts, but also the insights that genetics has provided about the histories of contemporary Jewish people. Much of the book is told through the lives of scientific pioneers. We meet Russian immigrant Maurice Fishberg; Australian Joseph Jacobs, the leading Jewish anthropologist in fin-de-siècle Europe; Chaim Sheba, a colorful Israeli geneticist and surgeon general of the Israeli Army; and Arthur Mourant, one of the foremost cataloguers of blood groups in the 20th century. As Ostrer describes their work and the work of others, he shows that to look over the genetics of Jewish groups, and to see the history of the Diaspora woven there, is truly a marvel. Here is what happened as the Jews migrated to new places and saw their numbers wax and wane, as they gained and lost adherents and thrived or were buffeted by famine, disease, wars, and persecution. Many of these groups--from North Africa, the Middle East, India--are little-known, and by telling their stories, Ostrer brings them to the forefront at a time when assimilation is literally changing the face of world Jewry. A fascinating blend of history, science, and biography, Legacy offers readers an entirely fresh perspective on the Jewish people and their history. It is as well a cutting-edge portrait of population genetics, a field which may soon take its place as a pillar of group identity alongside shared spirituality, shared social values, and a shared cultural legacy.
Download or read book The Metabolic Molecular Bases of Inherited Disease written by Charles R. Scriver and published by New York ; Montreal : McGraw-Hill. This book was released on 2001 with total page 6338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents clinical, biochemical, and genetic information concerning those metabolic anomalies grouped under inborn errors of metabolism.
Download or read book Abraham s Children written by Jon Entine and published by . This book was released on 2014-07-02 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract:
Download or read book DNA Tradition written by Yaakov Kleiman and published by Devora Publishing. This book was released on 2004 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Did the Twelve Tribes of Israel really exist? Are the scattered groups of modern Jews really the direct descendants of the ancient Hebrews of the Bible? This extraordinary book chronicles the latest discoveries in the cutting-edge field of Molecular Population Genetics that add empirical evidence and scientific confirmation to Biblical tradition.
Download or read book A Brief History of Everyone who Ever Lived written by Adam Rutherford and published by George Weidenfeld & Nicholson. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'A brilliant, authoritative, surprising, captivating introduction to human genetics. You'll be spellbound' Brian Cox This is a story about you. It is the history of who you are and how you came to be. It is unique to you, as it is to each of the 100 billion modern humans who have ever drawn breath. But it is also our collective story, because in every one of our genomes we each carry the history of our species - births, deaths, disease, war, famine, migration and a lot of sex. In this captivating journey through the expanding landscape of genetics, Adam Rutherford reveals what our genes now tell us about human history, and what history can now tell us about our genes. From Neanderthals to murder, from redheads to race, dead kings to plague, evolution to epigenetics, this is a demystifying and illuminating new portrait of who we are and how we came to be. *** 'A thoroughly entertaining history of Homo sapiens and its DNA in a manner that displays popular science writing at its best' Observer 'Magisterial, informative and delightful' Peter Frankopan 'An extraordinary adventure...From the Neanderthals to the Vikings, from the Queen of Sheba to Richard III, Rutherford goes in search of our ancestors, tracing the genetic clues deep into the past' Alice Roberts
Download or read book Critical Perspectives on Racial and Ethnic Differences in Health in Late Life written by National Research Council and published by National Academies Press. This book was released on 2004-10-16 with total page 753 pages. Available in PDF, EPUB and Kindle. Book excerpt: In their later years, Americans of different racial and ethnic backgrounds are not in equally good-or equally poor-health. There is wide variation, but on average older Whites are healthier than older Blacks and tend to outlive them. But Whites tend to be in poorer health than Hispanics and Asian Americans. This volume documents the differentials and considers possible explanations. Selection processes play a role: selective migration, for instance, or selective survival to advanced ages. Health differentials originate early in life, possibly even before birth, and are affected by events and experiences throughout the life course. Differences in socioeconomic status, risk behavior, social relations, and health care all play a role. Separate chapters consider the contribution of such factors and the biopsychosocial mechanisms that link them to health. This volume provides the empirical evidence for the research agenda provided in the separate report of the Panel on Race, Ethnicity, and Health in Later Life.
Download or read book Primer on the Autonomic Nervous System written by Phillip A. Low and published by Elsevier. This book was released on 2004-06-02 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Primer on the Autonomic Nervous System presents, in a readable and accessible format, key information about how the autonomic nervous system controls the body, particularly in response to stress. It represents the largest collection of world-wide autonomic nervous system authorities ever assembled in one book. It is especially suitable for students, scientists and physicians seeking key information about all aspects of autonomic physiology and pathology in one convenient source. Providing up-to-date knowledge about basic and clinical autonomic neuroscience in a format designed to make learning easy and fun, this book is a must-have for any neuroscientist's bookshelf! - Greatly amplified and updated from previous edition including the latest developments in the field of autonomic cardiovascular regulation and neuroscience - Provides key information about all aspects of autonomic physiology and pathology - Discusses stress and how its effects on the body are mediated - Compiles contributions by over 140 experts on the autonomic nervous system
Download or read book The Wandering Gene and the Indian Princess Race Religion and DNA written by Jeff Wheelwright and published by W. W. Norton & Company. This book was released on 2012-01-16 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: A brilliant and emotionally resonant exploration of science and family history. A vibrant young Hispano woman, Shonnie Medina, inherits a breast-cancer mutation known as BRCA1.185delAG. It is a genetic variant characteristic of Jews. The Medinas knew they were descended from Native Americans and Spanish Catholics, but they did not know that they had Jewish ancestry as well. The mutation most likely sprang from Sephardic Jews hounded by the Spanish Inquisition. The discovery of the gene leads to a fascinating investigation of cultural history and modern genetics by Dr. Harry Ostrer and other experts on the DNA of Jewish populations. Set in the isolated San Luis Valley of Colorado, this beautiful and harrowing book tells of the Medina family’s five-hundred-year passage from medieval Spain to the American Southwest and of their surprising conversion from Catholicism to the Jehovah’s Witnesses in the 1980s. Rejecting conventional therapies in her struggle against cancer, Shonnie Medina died in 1999. Her life embodies a story that could change the way we think about race and faith.
Download or read book Concise Handbook of Familial Cancer Susceptibility Syndromes written by and published by . This book was released on 2008 with total page 93 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Genetics Of Ashkenazi Jews written by Joshua Robbin Marks and published by Independently Published. This book was released on 2021-03-17 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the author of "Seed Of Israel: DNA Guide To Tracing Your Jewish Ancestry" comes this great dive into the history of Ashkenazi Jews. While controversial debates spark disagreements on the crystallization of this Jewish Diaspora, modern genetic studies and personal DNA samples finally conclude the Levantine Middle Eastern and Mediterranean roots of Ashkenazi ancestry: Judean people from the Holy Land that journeyed across the Mediterranean to the bottleneck of Europe.
Download or read book Direct to Consumer Genetic Testing written by National Research Council and published by National Academies Press. This book was released on 2011-01-16 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today, scores of companies, primarily in the United States and Europe, are offering whole genome scanning services directly to the public. The proliferation of these companies and the services they offer demonstrate a public appetite for this information and where the future of genetics may be headed; they also demonstrate the need for serious discussion about the regulatory environment, patient privacy, and other policy implications of direct-to-consumer (DTC) genetic testing. Rapid advances in genetic research already have begun to transform clinical practice and our understanding of disease progression. Existing research has revealed a genetic basis or component for numerous diseases, including Parkinson's disease, Alzheimer's disease, diabetes, heart disease, and several forms of cancer. The availability of the human genome sequence and the HapMap, plummeting costs of high-throughput screening, and increasingly sophisticated computational analyses have led to an explosion of discoveries of linkages between patterns of genetic variation and disease susceptibility. While this research is by no means a straight path toward better public health, improved knowledge of the genetic linkages has the potential to change fundamentally the way health professionals and public health practitioners approach the prevention and treatment of disease. Realizing this potential will require greater sophistication in the interpretation of genetic tests, new training for physicians and other diagnosticians, and new approaches to communicating findings to the public. As this rapidly growing field matures, all of these questions require attention from a variety of perspectives. To discuss some of the foregoing issues, several units of the National Academies held a workshop on August 31 and September 1, 2009, to bring together a still-developing community of professionals from a variety of relevant disciplines, to educate the public and policy-makers about this emerging field, and to identify issues for future study. The meeting featured several invited presentations and discussions on the many technical, legal, policy, and ethical questions that such DTC testing raises, including: (1) overview of the current state of knowledge and the future research trajectory; (2) shared genes and emerging issues in privacy; (3) the regulatory framework; and (4) education of the public and the medical community.
Download or read book The Origin of Ashkenazi Jewry written by Jits van Straten and published by Walter de Gruyter. This book was released on 2011-03-29 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Where do East European Jews – about 90 percent of Ashkenazi Jewry – descend from? This book conveys new insights into a century-old controversy. Jits van Straten argues that there is no evidence for the most common assumption that German Jews fled en masse to Eastern Europe to constitute East European Jewry. Dealing with another much debated theory, van Straten points to the fact that there is no way to identify the descendants of the Khazars in the Ashkenazi population. Using a multidisciplinary approach, the author draws heavily on demographic findings which are vital to evaluate the conclusions of modern DNA research. Finally, it is suggested that East European Jews are mainly descendants of Ukrainians and Belarussians. UPDATE: The article “The origin of East European Ashkenazim via a southern route” (Aschkenas 2017; 27(1): 239-270) is intended to clarify the origin of East European Jewry between roughly 300 BCE and 1000 CE. It is a supplement to this book.
