Download or read book NCI Chemical Carcinogen Reference Standard Repositories written by and published by . This book was released on 1992 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 2003 with total page 988 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Environmental Health Perspectives written by and published by . This book was released on 2000 with total page 1520 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Risk Assessment of Urban Air written by and published by . This book was released on 1994 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Annual Report written by National Cancer Institute (U.S.). Division of Cancer Etiology and published by . This book was released on 1987 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Standard and Reference Materials for Environmental Science written by National Status and Trends Program (U.S.) and published by . This book was released on 1995 with total page 814 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Omnibus Solicitation of the Public Health Service for Small Business Innovation Research SBIR written by and published by . This book was released on 1986 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Quinones and Quinone Enzymes Part A written by Helmut Sies and published by Elsevier. This book was released on 2004-05-01 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quinones are members of a class of aromatic compounds with two oxygen atoms bonded to the ring as carbonyl groups. This volume covers the role of quinines enzymes in cellular signalling and modulation of gene expression. *Coenzyme Q: Detection and Quinone Reductases *Plasma Membrane Quinone Reductases *Quinones, Cellular Signaling, and Modulation of Gene Expression

Download or read book Federal Biotechnology Information Resources Directory written by OMEC International and published by . This book was released on 1987 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book DNA Damage and Repair in Human Tissues written by Betsy M. Sutherland and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physical and chemical agents in the environment damage the DNA of humans, and pose a major threat to human health today, and to the genetic integrity of human populations. Although studies on isolated DNA in vitro, on prokaryotes, on mammalian cells in culture, and on laboratory animals have provided essential background information, it is now possible to study DNA damage and repair in human tissues directly. New techniques of high sensitivity, especially those not requiring radioactive labeling have made possible quantitation of DNA damage and repair, as well as detection of residual, unrepaired DNA lesions . In recent years, several investigators have taken up the challenge of studying damage and repair responses in humans, and we have chosen that work as the special focus of this Symposium. Major advances in under standing damage and responses in human skin, in blood cells and in human internal organs indicate three major themes. First, DNA damage levels in human tissues depend not only on the initial exposures, but also on the capapacity of that tissue for repair of the specific lesion type. Second, repair in human tissues may differ quantitatively and qualitatively from that in human cells in culture.

Download or read book DNA Repair Part A written by and published by Elsevier. This book was released on 2006-06-06 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA Repair, Part A provides detailed coverage of modern methods for molecular analysis of enzymes and enzyme systems that function in the maintenance of genome integrity. Coverage areas include base excision repair, nucleotide excision repair, translesion DNA polymerases, mismatch repair, genetic recombination, and double strand break repair. A laboratory standard for more than 40 years Over 400 volumes strong Also available on ScienceDirect Part A of a 2-part series

Download or read book Pharmaceutical Bioassays written by Shiqi Peng and published by John Wiley & Sons. This book was released on 2009-11-09 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive compendium of bioassay procedures and applications A virtual encyclopedia of key bioassay protocols, this up-to-date, essential resource reviews the methods and applications of bioassays that quantify drug activity and evaluate the validity of pharmacological models. Demonstrating the specific ways in which various pharmaceutical bioassays interpret the activity of drug molecules, the book covers the evaluation and screening of drug compounds in a wide spectrum of therapeutic categories. Throughout, the authors use various models to link experimental observations with findings that clarify the effect of drug compounds on cellular biology and measure the pharmacological activity of chemical substances. This provides an important technological platform for successful drug research and clinical therapy, making Pharmaceutical Bioassays an ideal sourcebook for pharmacologists, pharmaceutical and medical researchers, analytical chemists, toxicologists, and students. Just as a fundamental knowledge of pharmaceutical bioassays is vital to understanding how bioactive agents and new drugs are defined, discovered, and developed, so too is this indispensable reference, which: Offers a complete reference on pharmaceutical bioassays and their specific applications in the assessment of therapies for cancer, Alzheimer’s, diabetes, epilepsy, inflammation, antimalarials, pharmacogenomics, and other major therapeutic areas Covers bioassays that measure toxicity, including those for chemical toxicity and hepatoxicity—a particularly significant consideration in the development of safe and tolerable medications Highlights clinically relevant methods, ideas, and techniques to support any ­pharmaceutical researcher Suggests guidelines and systems to enhance communication between ­pharmacologists, chemists, and biologists Provides an informative analysis of pharmaceutical bioassay technologies and lab applications

Download or read book Annual Report Intramural Activities written by National Cancer Institute (U.S.). Division of Cancer Etiology and published by . This book was released on 1987 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Chemical Carcinogenesis written by Francisco Feo and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: About two centuries after the communication by Sir Percival Pott that the "chimney sweeper disease" was a cancer and its suggestion that active compounds of soot were the causative agents, and about one century after the description of urinary bladder cancer in dye workers, an enormous number of substances have been synthesized and have probably come into contact with man. Research in cancer prevention is of primary importance, and may receive continuous support from new discoveries on cancer etiology and pathogenesis. If one accepts the multistage model of chemical carcinogenesis, one has also to accept that many events occur between the contact of carcino genic compounds and their specific targets and the development of a clinically recognizable neoplasm. Thus, animal studies become essential to elucidate the different steps by which chemical carcinogens induce neoplasia. The analysis of these steps and the comparative evaluation of experimental models is essential to an understanding of pathogenesis.

Download or read book Fish Cancer Epidemics Oversight written by United States. Congress. House. Committee on Merchant Marine and Fisheries. Subcommittee on Fisheries and Wildlife Conservation and the Environment and published by . This book was released on 1984 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Annual Report National Cancer Institute Division of Cancer Cause and Prevention written by National Cancer Institute (U.S.). Division of Cancer Cause and Prevention and published by . This book was released on 1976 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Report on Carcinogens written by and published by . This book was released on 2000 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: