Download or read book National Toxicology Program s Chemical Solubility Compendium written by Lawrence H. Keith and published by CRC Press. This book was released on 2019-11-11 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a compilation of experimentally determined solubility ranges of over 1,700 compounds in the National Toxicology Program's Chemical Repository. Each compound's solubility was determined in a consistent manner in one to six solvents. Solvents chosen were those most commonly used for toxicology studies, spill cleanups, and chemical synthesis or chemical reaction experiments. These solvents include acetone, 95% ethanol, water, dimethyl sulfoxide, methanol, and toluene. Data for many of the research and industrial chemicals featured in this volume do not exist anywhere else. If you are a toxicologist, safety professional, industrial hygienist, or chemist, this book is a valuable reference tool you'll find yourself using every day.
Download or read book National Toxicology Program s Chemical Solubility Database written by Lawrence H. Keith and published by CRC Press. This book was released on 1991-12-20 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt: This database is a compilation of experimentally-determined solubility ranges of over 1,700 compounds in the National Toxicology Program's Chemical Repository. Each compound's solubility was determined in a consistent manner in one to six solvents. Solvents chosen were those most commonly used for toxicology studies, spill cleanups, and chemical synthesis or chemical reaction experiments. These solvents include acetone, 95% ethanol, water, dimethyl sulfoxide, methanol, and toluene. Data for many of the research and industrial chemicals featured in this database does not exist anywhere else. The database is also remarkably simple to use and offers many features that make finding information quick and easy. Compounds can be located by using partial names such as acids, amines, ketones, cyanides, and ethers. You can also locate compounds by using their CAS Number or by entering the specific chemical name. The program is entirely menu-driven and can perform Boolean "and/or" type searches. It comes equipped with one 3-1/2" diskette and one 5-1/4" diskette, a 20-page manual, and can run on IBM or IBM compatible hardware. Dos 2.0 or higher, 640K of internal memory, and 1mb of hard drive memory are required. National Toxicology Program's Chemical Solubility Database is a "must have" program for toxicologists, safety professionals and industrial hygienists, and chemists.
Download or read book The National Toxicology Program s Chemical Database written by Lawrence H. Keith and published by CRC Press. This book was released on 1991-12-31 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: This database provides a vast amount of information about potentially toxic chemicals to regulatory and research agencies, consultants, academics, and libraries. The National Toxicology Program's Chemical Database consists of eight volumes containing 50 fields that present detailed information on 2,270 different chemicals. The data is obtained from the literature or experimentally determined. Each compound is listed in every volume even when there is no information available for it in some volumes. Information in the NTP database was gathered and updated as compounds were used throughout a 12 year period from 1979 to 1991. Throughout the eight volumes, the primary chemical name and the Chemical Abstracts Service Registry Number (CAS No.) remain constant and all 2,270 chemicals are listed alphabetically in each volume. The NTP database can be sold as a set or individually. Each volume consists of one 3-1/2" and two 5-1/4" diskettes , in addition to a 64 page manual that describes how to use the software. Diskettes will run on IBM® or IBM-compatible equipment with DOS 2.0 and higher, 640K internal memory (RAM), and a hard drive with at least 2-17MB of available disk space. Use the eight volumes together to get the full benefit of the NTP Chemical Repository Database, or select only those volumes that contain the information you need and use them as stand-alone databases.
Download or read book The National Toxicology Program s Chemical Data Compendium written by Lawrence H. Keith and published by CRC Press. This book was released on 1992-02-04 with total page 1198 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Compendium provides a vast amount of information about potentially toxic chemicals to regulatory and research agencies, consultants, academics, and libraries.
Download or read book National Toxicology Program s Chemical Solubility Compendium written by Lawrence H. Keith and published by CRC Press. This book was released on 2019-11-11 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a compilation of experimentally determined solubility ranges of over 1,700 compounds in the National Toxicology Program's Chemical Repository. Each compound's solubility was determined in a consistent manner in one to six solvents. Solvents chosen were those most commonly used for toxicology studies, spill cleanups, and chemical synthesis or chemical reaction experiments. These solvents include acetone, 95% ethanol, water, dimethyl sulfoxide, methanol, and toluene. Data for many of the research and industrial chemicals featured in this volume do not exist anywhere else. If you are a toxicologist, safety professional, industrial hygienist, or chemist, this book is a valuable reference tool you'll find yourself using every day.
Download or read book National Toxicology Program Annual Report for Fiscal Year written by National Toxicology Program (U.S.) and published by . This book was released on 1991 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Some Chemicals that Cause Tumours of the Kidney Or Urinary Bladder in Rodents and Some Other Substances written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by World Health Organization. This book was released on 1999 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: Allyl isothiocyanate; ortho-Anisidine; Atrazine; Butyl benzyl phthalate; Chloroform; Chlorothalonil;Cyclamates;Dichlorobenzenes;Hexachlorobutadiene; Hexachloroethane; d-Limonene; Melamine; Methyl tert-butyl ether; Nitrilotriaceticacid andits salts;Paracetamol; ortho-Phenylphenol and its sodium salt; Potassium bromate ;Quercetin; Saccharin and its salts;Simazine
Download or read book Drug like Properties Concepts Structure Design and Methods written by Li Di and published by Elsevier. This book was released on 2010-07-26 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug discovery. If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process. The authors describe how properties affect in vivo pharmacological activity and impact in vitro assays. Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of property data in drug discovery and examples of structural modifications that have achieved improved property performance. The authors also review various methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties. - Serves as an essential working handbook aimed at scientists and students in medicinal chemistry - Provides practical, step-by-step guidance on property fundamentals, effects, structure-property relationships, and structure modification strategies - Discusses improvements in pharmacokinetics from a practical chemist's standpoint
Download or read book High Throughput Screening Methods in Toxicity Testing written by Pablo Steinberg and published by John Wiley & Sons. This book was released on 2013-02-26 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explores the benefits and limitations of the latest high-throughput screening methods With its expert coverage of high-throughput in vitro screening methods for toxicity testing, this book makes it possible for researchers to accelerate and streamline the evaluation and risk assessment of chemicals and drugs for toxicity. Moreover, it enables them to comply with the latest standards set forth by the U.S. National Research Council's "Toxicity Testing in the 21st Century: A Vision and Strategy" and the E.U.'s REACH legislation. Readers will discover a variety of state-of-the-science, high-throughput screening methods presented by a group of leading authorities in toxicology and toxicity testing. High-Throughput Screening Methods in Toxicity Testing is divided into five parts: General aspects, including predicting the toxicity potential of chemicals and drugs via high-throughput bioactivity profiling Assessing different cytotoxicity endpoints Assessing DNA damage and carcinogenesis Assessing reproductive toxicity, cardiotoxicity, and haematotoxicity Assessing drug metabolism and receptor-related toxicity Each chapter describes method principles and includes detailed information about data generation, data analysis, and applications in risk assessment. The authors not only enumerate the advantages of each high-throughput method over comparable conventional methods, but also point out the high-throughput method's limitations and potential pitfalls. In addition, the authors describe current research efforts to make high-throughput toxicity screening even more cost effective and streamlined. Throughout the book, readers will find plenty of figures and illustrations to help them understand and perform the latest high-throughput toxicity screening methods. This book is ideal for toxicologists and other researchers who need to implement high-throughput screening methods for toxicity testing in their laboratories as well as for researchers who need to evaluate the data generated by these methods.
Download or read book CRC Handbook of Chemistry and Physics written by William M. Haynes and published by CRC Press. This book was released on 2011-06-06 with total page 2624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mirroring the growth and direction of science for a century, the CRC Handbook of Chemistry and Physics, now in its 92nd edition, continues to be the most accessed and respected scientific reference in the world, used by students and Nobel Laureates. Available in its traditional print format, the Handbook is also available as an innovative interactive product on DVD and online. Among a wealth of enhancements, this edition analyzes, updates, and validates molecular formulas and weights, boiling and melting points, densities, and refractive indexes in the Physical Constants of Organic Compounds Table through comparisons with critically evaluated data from the NIST Thermodynamics Research Center. New Tables: Analytical Chemistry Abbreviations Used In Analytical Chemistry Basic Instrumental Techniques of Analytical Chemistry Correlation Table for Ultraviolet Active Functionalities Detection of Outliers in Measurements Polymer Properties Second Virial Coefficients of Polymer Solutions Updated Tables: Properties of the Elements and Inorganic Compounds Update of the Melting, Boiling, Triple, and Critical Points of the Elements Fluid Properties Major update and expansion of Viscosity of Gases table Major update and expansion of Thermal Conductivity of Gases table Major update of Properties of Cryogenic Fluids Major update of Recommended Data for Vapor-Pressure Calibration Expansion of table on the Viscosity of Liquid Metals Update of Permittivity (Dielectric Constant) of Gases table Added new refrigerant R-1234yf to Thermophysical Properties of Selected Fluids at Saturation table Molecular Structure and Spectroscopy Major update of Atomic Radii of the Elements Update of Bond Dissociation Energies Update of Characteristic Bond Lengths in Free Molecules Atomic, Molecular, and Optical Physics Update of Electron Affinities Update of Atomic and Molecular Polarizabilities Nuclear and Particle Physics Major update of the Table of the Isotopes Properties of Solids Major update and expansion of the Electron Inelastic Mean Free Paths table Update of table on Semiconducting Properties of Selected Materials Geophysics, Astronomy, and Acoustics Update of the Global Temperature Trend table to include 2010 data Health and Safety Information Major update of Threshold Limits for Airborne Contaminants The Handbook is also available as an eBook.
Download or read book CRC Handbook of Chemistry and Physics 93rd Edition written by William M. Haynes and published by CRC Press. This book was released on 2012-06-22 with total page 2657 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mirroring the growth and direction of science for a century, the Handbook, now in its 93rd edition, continues to be the most accessed and respected scientific reference in the world. An authoritative resource consisting tables of data, its usefulness spans every discipline. This edition includes 17 new tables in the Analytical Chemistry section, a major update of the CODATA Recommended Values of the Fundamental Physical Constants and updates to many other tables. The book puts physical formulas and mathematical tables used in labs every day within easy reach. The 93rd edition is the first edition to be available as an eBook.
Download or read book Toxicological Profile for Nitrophenols written by and published by . This book was released on 1992 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Report on Carcinogens written by and published by . This book was released on 2002 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Toxicologic Assessment of the Army s Zinc Cadmium Sulfide Dispersion Tests written by National Research Council and published by National Academies Press. This book was released on 1997-05-30 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the 1950s and 1960s, the U.S. Army conducted atmospheric dispersion tests in many American cities using fluorescent particles of zinc cadmium sulfide (ZnCdS) to develop and verify meteorological models to estimate the dispersal of aerosols. Upon learning of the tests, many citizens and some public health officials in the affected cities raised concerns about the health consequences of the tests. This book assesses the public health effects of the Army's tests, including the toxicity of ZnCdS, the toxicity of surrogate cadmium compounds, the environmental fate of ZnCdS, the extent of public exposures from the dispersion tests, and the risks of such exposures.
Download or read book Toxicological Profile for Barium and Compounds written by and published by . This book was released on 1992 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Hamilton and Hardy s Industrial Toxicology written by Raymond D. Harbison and published by John Wiley & Sons. This book was released on 2015-04-13 with total page 1364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a concise, yet comprehensive, reference on all aspects of industrial exposures and toxicants; this book aids toxicologists, industrial hygienists, and occupational physicians to investigate workplace health problems. • Updates and expands coverage with new chapters covering regulatory toxicology, toxicity testing, physical hazards, high production volume (HPV) chemicals, and workplace drug use • Includes information on occupational and environmental sources of exposure, mammalian toxicology, industrial hygiene, medical management and ecotoxicology • Retains a succinct chapter format that has become the hallmark for the previous editions • Distils a vast amount of information into one resource for both academics and professionals
Download or read book Scientific Directory and Annual Bibliography written by National Institutes of Health (U.S.) and published by . This book was released on 1987 with total page 686 pages. Available in PDF, EPUB and Kindle. Book excerpt:
