Download or read book Medications for Opioid Use Disorder Save Lives written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-06-16 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United States. Efforts to date have made no real headway in stemming this crisis, in large part because tools that already existâ€"like evidence-based medicationsâ€"are not being deployed to maximum impact. To support the dissemination of accurate patient-focused information about treatments for addiction, and to help provide scientific solutions to the current opioid crisis, this report studies the evidence base on medication assisted treatment (MAT) for OUD. It examines available evidence on the range of parameters and circumstances in which MAT can be effectively delivered and identifies additional research needed.

Download or read book Overcoming Opioid Addiction The Authoritative Medical Guide for Patients Families Doctors and Therapists written by Adam Bisaga and published by The Experiment, LLC. This book was released on 2018-05-01 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: From a leading addiction expert, a desperately needed medical guide to understanding, treating, and finally defeating opioid use disorder Drug overdoses are now the leading cause of death for Americans under the age of 50, claiming more lives than the AIDs epidemic did at its peak. Opioid abuse accounts for two-thirds of these overdoses, with over 100 Americans dying from opioid overdoses every day. Now Overcoming Opioid Addiction provides a comprehensive medical guide for opioid use disorder (OUD) sufferers, their loved ones, clinicians, and other professionals. Here is expertly presented, urgently needed information and guidance, including: Why treating OUD is unlike treating any other form of drug dependency The science that underlies addiction to opioids, and a clear analysis of why this epidemic has become so deadly The different stages and effective methods of treatment, including detoxification vs. maintenance medications, as well as behavioral therapies How to deal with relapses and how to thrive despite OUD Plus a chapter tailored to families with crucial, potentially life-saving information, such as how to select the best treatment program, manage medications, and reverse an overdose.

Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Download or read book Drug Addiction and Drug Policy written by William N. Brownsberger and published by Harvard University Press. This book was released on 2009-06-30 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the culmination of five years of debate among distinguished scholars in law, public policy, medicine, and biopsychology, about the most difficult questions in drug policy and the study of addictions. Do drug addicts have an illness, or is the addiction under their control? Should they be treated as patients or as criminals? Challenging the conventional wisdom, the authors show that these standard dichotomies are false.

Download or read book Neuropathology of Drug Addictions and Substance Misuse Volume 1 written by Victor R Preedy and published by Academic Press. This book was released on 2016-03-07 with total page 1134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuropathology of Drug Addictions and Substance Misuse, Volume One: Foundations of Understanding, Tobacco, Alcohol, Cannabinoids, Opioids and Emerging Addictions provides the latest research in an area that shows that the neuropathological features of one addiction are often applicable to those of others. The book also details how a further understanding of these commonalties can provide a platform for the study of specific addictions in greater depth, all in an effort to create new modes of understanding, causation, prevention, and treatment. The three volumes in this series address new research and challenges, offering comprehensive coverage on the adverse consequences of the most common drugs of abuse, with each volume serving to update the reader's knowledge on the broader field of addiction, while also deepening our understanding of specific addictive substances. Volume One addresses tobacco, alcohol, cannabinoids, and opioids, with each section providing data on the general, molecular/cellular, and structural/functional neurological aspects of a given substance, along with a focus on the adverse consequences of addictions. - Provides a modern approach on the pathology of substances of abuse, offering an evidence based ethos for understanding the neurology of addictions - Fills an existing gap in the literature by proving a one-stop-shopping synopsis of everything to do with the neuropathology of drugs of addiction and substance misuse - Includes a list of abbreviations, abstracts, applications to other addictions and substance misuse, mini-dictionary of terms, summary points, 6+ figures and tables, and full references in each chapter - Offers coverage of preclinical, clinical, and population studies, from the cell to whole organs, and the genome to whole body

Download or read book Cognitive Clinical and Neural Aspects of Drug Addiction written by Ahmed A. Moustafa and published by Academic Press. This book was released on 2020-01-17 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cognitive, Clinical, and Neural Aspects of Drug Addiction focuses on the theories that cause drug addiction, including avoidance behavior, self-medication, reward sensitization, behavioral inhibition and impulsivity. Dr. Moustafa takes this book one-step further by reviewing the psychological causes of relapse, including the role stress, anxiety and depression play. By examining both the causes of drug addiction and relapse, this book will help clinicians create individualized treatment options for their patients suffering from drug addiction. Understanding the development of individual drug addictions are often difficult to understand and, more often, difficult to treat. The most successful treatments begin with studying why individuals become addicted to drugs and how to change their thinking and behavior.

Download or read book Drugs Addiction and the Brain written by George F. Koob and published by Academic Press. This book was released on 2014-07-12 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain. - Full-color circuitry diagrams of brain regions implicated in each stage of the addiction cycle - Actual data figures from original sources illustrating key concepts and findings - Introduction to basic neuropharmacology terms and concepts - Introduction to numerous animal models used to study diverse aspects of drug use. - Thorough review of extant work on the neurobiology of addiction

Download or read book American Overdose written by Chris McGreal and published by PublicAffairs. This book was released on 2018-11-13 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive portrait of a uniquely American epidemic -- devastating in its findings and damning in its conclusions The opioid epidemic has been described as "one of the greatest mistakes of modern medicine." But calling it a mistake is a generous rewriting of the history of greed, corruption, and indifference that pushed the US into consuming more than 80 percent of the world's opioid painkillers. Journeying through lives and communities wrecked by the epidemic, Chris McGreal reveals not only how Big Pharma hooked Americans on powerfully addictive drugs, but the corrupting of medicine and public institutions that let the opioid makers get away with it. The starting point for McGreal's deeply reported investigation is the miners promised that opioid painkillers would restore their wrecked bodies, but who became targets of "drug dealers in white coats." A few heroic physicians warned of impending disaster. But American Overdose exposes the powerful forces they were up against, including the pharmaceutical industry's coopting of the Food and Drug Administration and Congress in the drive to push painkillers -- resulting in the resurgence of heroin cartels in the American heartland. McGreal tells the story, in terms both broad and intimate, of people hit by a catastrophe they never saw coming. Years in the making, its ruinous consequences will stretch years into the future.

Download or read book Creating the American Junkie written by Caroline Jean Acker and published by JHU Press. This book was released on 2002-04-26 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heroin was only one drug among many that worried Progressive Era anti-vice reformers, but by the mid-twentieth century, heroin addiction came to symbolize irredeemable deviance. Creating the American Junkie examines how psychiatrists and psychologists produced a construction of opiate addicts as deviants with inherently flawed personalities caught in the grip of a dependency from which few would ever escape. Their portrayal of the tough urban addict helped bolster the federal government's policy of drug prohibition and created a social context that made the life of the American heroin addict, or junkie, more, not less, precarious in the wake of Progressive Era reforms. Weaving together the accounts of addicts and researchers, Acker examines how the construction of addiction in the early twentieth century was strongly influenced by the professional concerns of psychiatrists seeking to increase their medical authority; by the disciplinary ambitions of pharmacologists to build a drug development infrastructure; and by the American Medical Association's campaign to reduce prescriptions of opiates and to absolve physicians in private practice from the necessity of treating difficult addicts as patients. In contrast, early sociological studies of heroin addicts formed a basis for criticizing the criminalization of addiction. By 1940, Acker concludes, a particular configuration of ideas about opiate addiction was firmly in place and remained essentially stable until the enormous demographic changes in drug use of the 1960s and 1970s prompted changes in the understanding of addiction—and in public policy.

Download or read book Pain Killer written by Barry Meier and published by Rodale. This book was released on 2003-10-17 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines OxyContin, the so-called miracle prescription drug that swept the nation but led to overdoes and addiction, providing a look at the multi-billion-dollar pain managment business, its excesses and its abuses.

Download or read book Drugs Brains and Behavior written by and published by . This book was released on 2007 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Behavioral Neuroscience of Drug Addiction written by David W. Self and published by Springer Science & Business Media. This book was released on 2009-12-18 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug addiction is a chronically relapsing mental illness involving severe motivational disturbances and loss of behavioral control leading to personal dev- tation. The disorder af?icts millions of people, often co-occurring with other mental illnesses with enormous social and economic costs to society. Several decades of research have established that drugs of abuse hijack the brain’s natural reward substrates, and that chronic drug use causes aberrant alterations in these rewa- processing systems. Such aberrations may be demonstrated at the cellular, neu- transmitter, and regional levels of information processing using either animal models or neuroimaging in humans following chronic drug exposure. Behaviorally, these neural aberrations manifest as exaggerated, altered or dysfunctional expr- sion of learned behavioral responses related to the pursuit of drug rewards, or to environmental factors that precipitate craving and relapse during periods of drug withdrawal. Current research efforts are aimed at understanding the associative and causal relationships between these neurobiological and behavioral events, such that treatment options will ultimately employ therapeutic amelioration of neural de?cits and restoration of normal brain processing to promote efforts to abstain from further drug use. The Behavioral Neuroscience of Drug Addiction, part of the Springer series on Current Topics in Behavioral Neurosciences, contains scholarly reviews by noted experts on multiple topics from both basic and clinical neuroscience ?elds.

Download or read book In Pain written by Travis Rieder and published by HarperCollins. This book was released on 2019-06-18 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: NPR Best Book of 2019 A bioethicist’s eloquent and riveting memoir of opioid dependence and withdrawal—a harrowing personal reckoning and clarion call for change not only for government but medicine itself, revealing the lack of crucial resources and structures to handle this insidious nationwide epidemic. Travis Rieder’s terrifying journey down the rabbit hole of opioid dependence began with a motorcycle accident in 2015. Enduring half a dozen surgeries, the drugs he received were both miraculous and essential to his recovery. But his most profound suffering came several months later when he went into acute opioid withdrawal while following his physician’s orders. Over the course of four excruciating weeks, Rieder learned what it means to be “dope sick”—the physical and mental agony caused by opioid dependence. Clueless how to manage his opioid taper, Travis’s doctors suggested he go back on the drugs and try again later. Yet returning to pills out of fear of withdrawal is one route to full-blown addiction. Instead, Rieder continued the painful process of weaning himself. Rieder’s experience exposes a dark secret of American pain management: a healthcare system so conflicted about opioids, and so inept at managing them, that the crisis currently facing us is both unsurprising and inevitable. As he recounts his story, Rieder provides a fascinating look at the history of these drugs first invented in the 1800s, changing attitudes about pain management over the following decades, and the implementation of the pain scale at the beginning of the twenty-first century. He explores both the science of addiction and the systemic and cultural barriers we must overcome if we are to address the problem effectively in the contemporary American healthcare system. In Pain is not only a gripping personal account of dependence, but a groundbreaking exploration of the intractable causes of America’s opioid problem and their implications for resolving the crisis. Rieder makes clear that the opioid crisis exists against a backdrop of real, debilitating pain—and that anyone can fall victim to this epidemic.

Download or read book Addicts Who Survived written by David T. Courtwright and published by Univ. of Tennessee Press. This book was released on 2013-01-25 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors employ the techniques of oral history to penetrate the nether world of the drug user, giving us an engrossing portrait of life in the drug subculture during the "classic" era of strict narcotic control. Praise for the hardcover edition: "A momentous book which I feel is destined to become a classic in the category of scholarly narcotic books." —Claude Brown, author of the bestseller, Manchild in the Promised Land. "The drug literature is filled with the stereotyped opinions of non-addicted, middle-class pundits who have had little direct contact with addicts. These stories are reality. Narcotic addicts of the inner cities are both tough and gentle, deceptive when necessary and yet often generous--above all, shrewd judges of character. While judging them, the clinician is also being judged." —Vincent P. Dole, M.D., The Rockefeller Institute. "What was it like to be a narcotic addict during the Anslinger era? No book will probably ever appear that gives a better picture than this one. . . . a singularly readable and informative work on a subject ordinarily buried in clichés and stereotypes." —Donald W. Goodwin, Journal of the American Medical Association " . . . an important contribution to the growing body of literature that attempts to more clearly define the nature of drug addiction. . . . [This book] will appeal to a diverse audience. Academicians, politicians, and the general reader will find this approach to drug addiction extremely beneficial, insightful, and instructive. . . . Without qualification anyone wishing to acquire a better understanding of drug addicts and addiction will benefit from reading this book." —John C. McWilliams, Pennsylvania Magazine of History and Biography "This study has much to say to a general audience, as well as those involved in drug control." —Publishers Weekly "The authors' comments are perceptive and the interviews make interesting reading." —John Duffy, Journal of American History "This book adds a vital and often compelling human dimension to the story of drug use and law enforcement. The material will be of great value to other specialists, such as those interested in the history of organized crime and of outsiders in general." —H. Wayne Morgan, Journal of Southern History "This book represents a significant and valuable addition to the contemporary substance abuse literature. . . . this book presents findings from a novel and remarkably imaginative research approach in a cogent and exceptionally informative manner." —William M. Harvey, Journal of Psychoactive Drugs "This is a good and important book filled with new information containing provocative elements usually brought forth through the touching details of personal experience. . . . There isn't a recollection which isn't of intrinsic value and many point to issues hardly ever broached in more conventional studies." —Alan Block, Journal of Social History

Download or read book Geography and Drug Addiction written by Yonette F. Thomas and published by Springer Science & Business Media. This book was released on 2008-09-24 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Making Connections: Geography and Drug Addiction Geography involves making connections – connections in our world among people and places, cultures, human activities, and natural processes. It involves understa- ing the relationships and ‘connections’ between seemingly disparate or unrelated ideas and between what is and what might be. Geography also involves connecting with people. When I rst encountered an extraordinarily vibrant, intelligent, and socially engaged scientist at a private d- ner several years ago, I was immediately captivated by the intensity of her passion to understand how and why people become addicted to drugs, and what could be done to treat or prevent drug addiction. Fortunately, she was willing to think beyond the bounds of her own discipline in her search for answers. Our conversation that evening, which began with her research on fundamental biochemical processes of drug addiction in the human body, evolved inevitably to an exploration of the ways in which research on the geographical context of drug addiction might contribute to the better understanding of etiology of addiction, its diffusion, its interaction with geographically variable environmental, social, and economic factors, and the strategies for its treatment and prevention. This fascinating woman, I soon learned, was Nora Volkow, the Director of the National Institute on Drug Abuse as well as the granddaughter of Leon Trotsky.

Download or read book Drug Abuse and Addiction in Medical Illness written by Joris C. Verster and published by Springer Science & Business Media. This book was released on 2012-07-06 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug abuse and addiction are common in clinical practice. Often they interfere with patient treatment or require an alternative approach. Drug Abuse and Addiction in Medical Illness: Causes, Consequences, and Treatment is a major contribution to the literature, a gold standard title offering a comprehensive range of topics for those who care for patients with addiction, conduct research in this area, or simply have an interest in the field. Offering state-of-the-art information for all those working with drug abusing or addicted patients, or for those interested in this topic from other research perspectives, the volume is a first of its kind book -- rich, comprehensive, yet focused, addressing the needs of the very active theoretical, basic, and clinical research in the field. Comprised of 46 chapters organized in four sections and developed by the leading international experts, Drug Abuse and Addiction in Medical Illness: Causes, Consequences, and Treatment covers virtually every core, as well as contemporary, topic on addiction, from the established theories to the most modern research and development in the field. Enhancing the educational value of the volume, every chapter includes an abstract and two boxes summarizing learning objectives and directions for future research. Drug Abuse and Addiction in Medical Illness: Causes, Consequences, and Treatment discusses the topic in a authoritative, systematic manner and is an indispensable reference for all clinicians and researchers interested in this rapidly changing field.

Download or read book Treatment Improvement Protocol TIP 63 Medications for Opioid Use Disorder written by Substance Abuse Mental Health Services Administration/SAMHSA (U.S.) and published by Government Printing Office. This book was released on 2018-06-05 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Treatment Improvement Protocol (TIP) reviews the use of the three Food and Drug Administration (FDA)-approved medications used to treat opioid use disorder (OUD)—methadone, naltrexone, and buprenorphine—and provides guidance for healthcare professionals and addiction treatment providers on appropriate prescribing practices for these medications and effective strategies for supporting the patients utilizing medication for the treatment of OUD. The goal of treatment for opioid addiction or OUD is remission of the disorder leading to lasting recovery. Recovery is a process of change through which individuals improve their health and wellness, live self-directed lives, and strive to reach their full potential. This TIP also educates patients, families, and the general public about how OUD medications work and the benefits they offer. Related products: Medication-Assisted Treatment of Opioid Use Disorder: Pocket Guide A Shared Burden: The Military and Civilian Consequences of Army Pain Management Since 2001 Click our Alcoholism, Smoking & Substance Abuse collection to find more resources on this topic.