Download or read book Bio Nano Interface written by Manoranjan Arakha and published by Springer Nature. This book was released on 2021-11-27 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the unique interactions of nanoparticles with various biomolecules under different environmental conditions. It describes the consequences of these interactions on other biological aspects like flora and fauna of the niche, cell proliferation, etc. The book provides information about the novel and eco-friendly nanoparticle synthesis methods, such as continuous synthesis of nanoparticles using microbial cells. Additionally, the book discusses nanoparticles' potential impact in different areas of biological sciences like food, medicine, agriculture, and the environment. Due to their advanced physicochemical properties, nanoparticles have revolutionized biomedical and pharmaceutical sciences. Inside the biological milieu, nanoparticles interact with different moieties to adopt stable shape, size, and surface functionalities and form nano-biomolecular complexes. The interaction pattern at the interface form complexes determines the fate of interacting biomolecules and nanoparticles inside the biological system. Understanding the interaction pattern at the nano-bio interface is crucial for the safe use of nanoparticles in natural sciences. This book rightly addresses all questions about the interaction and the ensuing structure and function of these nano-biomolecular complexes. This book caters to students and researchers in the area of biotechnology, microbiology, and pharmaceutical sciences.
Download or read book Nanoparticle biological Interfaces written by Cristina Rodriguez-Quijada and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Protein Nanoparticle Interactions written by Masoud Rahman and published by Springer Science & Business Media. This book was released on 2013-06-24 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the fabrication of nanomaterials and exploration of their properties have attracted the attention of various scientific disciplines such as biology, physics, chemistry, and engineering. Although nanoparticulate systems are of significant interest in various scientific and technological areas, there is little known about the safety of these nanoscale objects. It has now been established that the surfaces of nanoparticles are immediately covered by biomolecules (e.g. proteins, ions, and enzymes) upon their entrance into a biological medium. This interaction with the biological medium modulates the surface of the nanoparticles, conferring a “biological identity” to their surfaces (referred to as a “corona”), which determines the subsequent cellular/tissue responses. The new interface between the nanoparticles and the biological medium/proteins, called “bio-nano interface,” has been very rarely studied in detail to date, though the interest in this topic is rapidly growing. In this book, the importance of the physiochemical characteristics of nanoparticles for the properties of the protein corona is discussed in detail, followed by comprehensive descriptions of the methods for assessing the protein-nanoparticle interactions. The advantages and limitations of available corona evaluation methods (e.g. spectroscopy methods, mass spectrometry, nuclear magnetic resonance, electron microscopy, X-ray crystallography, and differential centrifugal sedimentation) are examined in detail, followed by a discussion of the possibilities for enhancing the current methods and a call for new techniques. Moreover, the advantages and disadvantages of protein-nanoparticle interaction phenomena are explored and discussed, with a focus on the biological impacts.
Download or read book Nanomaterial Interfaces in Biology written by Paolo Bergese and published by Humana. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The intersection of nanotechnology with biology has given rise to numerous ideas for new ways to use nanotechnology for biological applications. Nanomaterials possess unique size- and material-dependent properties which make them attractive for improving regular biomedical fields, such as drug delivery, imaging, therapy, and diagnostics. Divided into three convenient sections, Nanomaterial Interfaces in Biology: Methods and Protocols covers protocols describing synthesis, fabrication, and construction of bio-nanomaterial interfaces, characterization protocols of bio-nanomaterial interfaces, and applications which utilize the bio-nanomaterial interfaces. Written in the highly successful Methods in Molecular Biology series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible Nanomaterial Interfaces in Biology: Methods and Protocols will serve the new and emerging scientific community, enabling new capabilities and technologies that were not previously possible in medicine and biology.
Download or read book Microbial Interactions at Nanobiotechnology Interfaces written by R. Navanietha Krishnaraj and published by John Wiley & Sons. This book was released on 2021-10-26 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: MICROBIAL INTERACTIONS AT NANOBIOTECHNOLOGY INTERFACES This book covers a wide range of topics including synthesis of nanomaterials with specific size, shape, and properties, structure-function relationships, tailoring the surface of nanomaterials for improving the properties, interaction of nanomaterials with proteins/microorganism/eukaryotic cells, and applications in different sectors. This book also provides a strong foundation for researchers who are interested to venture into developing functionalized nanomaterials for any biological applications in their research. Practical concepts such as modelling nanomaterials, and simulating the molecular interactions with biomolecules, transcriptomic or genomic approaches, advanced imaging techniques to investigate the functionalization of nanomaterials/interaction of nanomaterials with biomolecules and microorganisms are some of the chapters that offer significant benefits to the researchers.
Download or read book Nanocomposite Particles for Bio Applications written by Tito Trindade and published by CRC Press. This book was released on 2011-08-08 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a concise state of the art of the synthesis and properties of nanocomposite particles with interest for diverse bio-applications. Contributions are mainly related to the chemical design of nanocomposite particles, their properties as well as their constituent materials, and the tailoring of bio-interfaces that may be relevant to
Download or read book Bio Nano Interfaces written by Wolfgang Parak and published by CRC Press. This book was released on 2024-02-27 with total page 1480 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent decades, bio-nano interfaces have become a popular topic of research. The interface between biology (e.g., cells, proteins) and man-made materials (e.g., surfaces of labware, medical devices/implants, etc., that are exposed to the biological matter) has always been important, way before the terms of nanotechnology and nanoscience were coined. Nanotechnology brought new techniques into play, with which such interfaces can be investigated with an additional viewpoint. This book is a collection of articles spanning two decades that shows how the newer publications have evolved from the older ones. This allows the reader to see the development in the field not only technically but also conceptually. The book is, in particular, suitable for the researchers and general readers who are looking for inspiration on how ideas develop over decades.
Download or read book Nanozymes Next Wave of Artificial Enzymes written by Xiaoyu Wang and published by Springer. This book was released on 2016-07-27 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the fundamental concepts, the latest developments and the outlook of the field of nanozymes (i.e., the catalytic nanomaterials with enzymatic characteristics). As one of today’s most exciting fields, nanozyme research lies at the interface of chemistry, biology, materials science and nanotechnology. Each of the book’s six chapters explores advances in nanozymes. Following an introduction to the rise of nanozymes research in the course of research on natural enzymes and artificial enzymes in Chapter 1, Chapters 2 through 5 discuss different nanomaterials used to mimic various natural enzymes, from carbon-based and metal-based nanomaterials to metal oxide-based nanomaterials and other nanomaterials. In each of these chapters, the nanomaterials’ enzyme mimetic activities, catalytic mechanisms and key applications are covered. In closing, Chapter 6 addresses the current challenges and outlines further directions for nanozymes. Presenting extensive information on nanozymes and supplemented with a wealth of color illustrations and tables, the book offers an ideal guide for readers from disparate areas, including analytical chemistry, materials science, nanoscience and nanotechnology, biomedical and clinical engineering, environmental science and engineering, green chemistry, and novel catalysis.
Download or read book Nanoparticles in Biology and Medicine written by Enrico Ferrari and published by Humana. This book was released on 2021-03-24 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully updated volume presents a wide range of methods for synthesis, surface modification, characterization and application of nano-sized materials (nanoparticles) in the life science and medical fields, with a focus on drug delivery and diagnostics. Beginning with a section on the synthesis of nanoparticles and their applications, the book continues with detailed chapters on nanoparticle derivatization, bio-interface, and nanotoxicity, as well as nanoparticle characterization and advanced methods development. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Nanoparticles in Biology and Medicine: Methods and Protocols, Second Edition serves as an ideal guide for scientists at all levels of expertise to a wide range of biomedical and pharmaceutical applications including functional protein studies, drug delivery, immunochemistry, imaging, and more.
Download or read book Computational Studies at Nanomaterial biological Interfaces written by Dongyue Liang and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomaterials are playing increasingly important roles in modern industry, and its applications are expanding rapidly. This, however, also leads to their exposure to the biological environment, and their environmental impacts are not well-understood. To aid the design of next generation of environmental friendly nanomaterials, understandings at the causality level is required, and computer simulations could serve as a powerful tool to obtain molecular level pictures of nano-bio interfaces. In this thesis, we present all-atom simulations at QM, MM and QM/MM levels to study several nano-bio interfaces of interest. The studies can be summarized into two topics: (1) Explicit description of solvation plays important role in many computational studies of kinetics and thermodynamics at nanomaterial-water interface, but often difficult to include especially at QM level due to high computational cost. Along this line, we studied ligand adsorption onto gold surface adapting a promising QM/MM methodology, and cross-benchmarked with QM and MM methods. We also applied QM and MM methods to develop a force field suitable for characterizing LiCoO$_2$-water interface, and to understand interfacial behaviors of water and other molecules. (2) Experimental characterizations of ligand functionalized nanoparticles (NPs) are not always straightforward to interpret at molecular level. We applied MD simulations to study electrostatic properties and relaxation times of functionalized NPs, aiming to establish connections between experimental measured properties and molecular features, and aid the design of functionalized NPs.
Download or read book Nanomaterial written by David G. Capco and published by Springer Science & Business Media. This book was released on 2014-03-28 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapidly developing field of nanomaterials has expanded in many commercial areas. More recent studies have begun to provide a foundation for understanding how nanomaterials influence cells and how they also can serve as methodological tools for studies in medicine and cell biology, including research into stem cells. Recent investigations have shown affects of nanomaterials on specific subcellular structures, such as the actin-based brush border network in cells with an increasing emphasis on the barrier function of epithelial tissues. While other studies have shown involvement of nanoparticles in specific cytoplasmic signal transduction events such as the rise in intracellular free calcium, a signaling event known to regulate many changes in cell architecture and function. In parallel, nanomaterials are increasingly used in medicine for drug delivery, treatment of cancer and an increasing number of new applications. This book investigates these areas and also includes new methods for assessment in cell biology and medicine.
Download or read book Biosensors Nanotechnology written by Ashutosh Tiwari and published by John Wiley & Sons. This book was released on 2014-06-26 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides detailed reviews of a range of nanostructures used in the construction of biosensors as well as the applications of these biosensor nanotechnologies in the biological, chemical, and environmental monitoring fields Biological sensing is a fundamental tool for understanding living systems, but also finds practical application in medicine, drug discovery, process control, food safety, environmental monitoring, defense, and personal security. Moreover, a deeper understanding of the bio/electronic interface leads us towards new horizons in areas such as bionics, power generation, and computing. Advances in telecommunications, expert systems, and distributed diagnostics prompt us to question the current ways we deliver healthcare, while robust industrial sensors enable new paradigms in R&D and production. Despite these advances, there is a glaring absence of suitably robust and convenient sensors for body chemistries. This book examines some of the emerging technologies that are fueling scientific discovery and underpinning new products to enhance the length and quality of our lives. The 14 chapters written by leading experts cover such topics as: ZnO and graphene microelectrode applications in biosensing Assembly of polymers/metal nanoparticles Gold nanoparticle-based electrochemical biosensors Impedimetric DNA sensing employing nanomaterials Graphene and carbon nanotube-based biosensors Computational nanochemistry study of the BFPF green fluorescent protein chromophore Biosynthesis of metal nanoparticles Bioconjugated-nanoporous gold films in electrochemical biosensors The combination of molecular imprinting and nanotechnology Principles and properties of multiferroics and ceramics
Download or read book Surface Design Applications in Bioscience and Nanotechnology written by Renate Förch and published by John Wiley & Sons. This book was released on 2009-07-13 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: This carefully selected balance of tutorial-like review chapters and advanced research covers hot topics in the field of biointerfaces, biosensing, nanoparticles at interfaces, and functionalized quantum dots. It also includes chapters arising from non-published work with topics such as surface design and their applications, as well as new developments in analytical tools for materials science and life science. Based on the very close and complementary collaboration of three distinguished leading research groups, this book highlights recent advances in the field ranging from synthesis and fabrication of organic and polymeric materials, surface and interface science to advanced analytical methods. It thus addresses new concepts in micro- and nanofabrication, bio-nanotechnology, biosensors and the necessary compositional and structural analysis. Particular attention is paid throughout to complex hierarchical interface architectures and possible applications of the chemical and physical methodologies discussed, covering bio-diagnostics, novel biosensors and adhesion science. With its unique combination of expertise from chemistry, physics, biology, surface science and engineering, this is a valuable companion for students, practitioners and established experts.
Download or read book Nanoparticles in Biology and Medicine written by Mikhail Soloviev and published by Methods in Molecular Biology. This book was released on 2012-07-13 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: The modern fascination with micro- and nano-sized materials can actually be traced back further to the 1960s and ‘70s when the first few reported attempts were made to use nanoparticles for controlled drug delivery. In Nanoparticles in Biology and Medicine: Methods and Protocols, experts in the field present a wide range of methods for synthesis, surface modification, characterization, and application of nano-sized materials (nanoparticles) in life science and medical fields, mostly for drug delivery. The methods presented cover all stages of nanoparticle manufacturing, modification, analysis, and applications. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Nanoparticles in Biology and Medicine: Methods and Protocols will help the beginner become familiar with this fascinating field and will provide scientists at all levels of expertise with easy-to-follow practical advice needed to make, modify, and analyze nanoparticles of their choice and to use them in a wide range of biomedical and pharmaceutical applications, including functional protein studies, drug delivery, immunochemistry, imaging, and many others.
Download or read book Nanoparticle Protein Corona written by Ashutosh Kumar and published by Royal Society of Chemistry. This book was released on 2019-07-26 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoparticles have numerous biomedical applications including drug delivery, bone implants and imaging. A protein corona is formed when proteins existing in a biological system cover the nanoparticle surface. The formation of a nanoparticle–protein corona, changes the behaviour of the nanoparticle, resulting in new biological characteristics and influencing the circulation lifetime, accumulation, toxicity, cellular uptake and agglomeration. This book provides a detailed understanding of nanoparticle–protein corona formation, its biological significance and the factors that govern the formation of coronas. It also explains the impact of nanoparticle–protein interactions on biological assays, ecotoxicity studies and proteomics research. It will be of interest to researchers studying the application of nanoparticles as well as toxicologists and pharmaceutical chemists.
Download or read book Engineering the Nano bio Interface of Gold Nanoparticles for Biomedical Applications written by Ying Jiang and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Gold nanoparticles (AuNPs) have emerged as a promising platform for a myriad of biomedical applications, including sensing, drug delivery, and antibiotics. In this thesis, I have studied and engineered the interface of AuNPs with different biological systems, demonstrating a large variety of biomedical applications by modulation of these interfaces. My research was initially focused on systematically tuning the physicochemical properties of nanoparticles to understand nano-bio interactions at the cellular level. The results demonstrate that size and surface charge of AuNP interact in an interrelated fashion to modulate nanoparticle internalization by cells, providing an engineering strategy for designing nanomaterials for drug delivery applications. Later, I engineered an environmentally responsive nanoparticle-protein interface for real time hydrogen peroxide (H2O2) sensing and monitoring of cellular oxidative stress. The responsiveness of this system demonstrates the utility of co-engineering synthetic-biological hybrid nanomaterials. Moreover, I developed gold nanoparticle-stabilized nanocapsules (NPSCs) for in vitro and in vivo gene delivery to enhance cancer therapy and immunomodulation efficiency. Finally, I demonstrated the use of gold nanoparticles to combat with pathogenic bacteria. The NP surface ligand chemistry and activity relationship reveals a new aspect to designing and constructing antimicrobial nanoparticles. In summary, the findings in this thesis highlight that systematically tuning the physicochemical properties of nanoparticles provides a powerful means to control interactions with biological systems, enabling new biological and therapeutic applications.
Download or read book Lateral Flow Immunoassay written by Raphael Wong and published by Springer Science & Business Media. This book was released on 2008-12-16 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to the simplicity, relative accuracy, fast result reporting, and user-friendliness of lateral flow immunoassay, its use has undergone tremendous growth in the diagnostic industry in the last few years. Such technology has been utilized widely and includes pregnancy and woman's health determination, cardiac and emergency conditions monitoring and testing, infectious disease including Flu screening, cancer marker screening, and drugs abuse testing. This book covers the scope of utilization, the principle of the technology, the patent concerns, information on the development and production of the test device and specific applications will be of interest to the diagnostic industry and the general scientific community.
