Download or read book N Sulfonated N Heterocycles written by Galal H. Elgemeie and published by Elsevier. This book was released on 2022-08-30 with total page 523 pages. Available in PDF, EPUB and Kindle. Book excerpt: N-Sulfonated-N-Heterocycles covers the synthesis, chemistry and biological applications of these compounds, focusing on pioneering synthetic approaches, mechanistic insights and their limitations, as well as recent advances in this field. The synthesis of some of N-sulfonated N-heterocycles and their transformation to other useful cyclic and acyclic compounds are discussed, as well as their uses as useful intermediates in the preparation of polymeric and medicinal materials. This book includes detailed methods and protocols, and the focus on applications makes this resource an essential guide for all researchers in the area of organic, medicinal and polymeric synthetic study. - Reviews the use of N-sulfonated N-heterocycles as important precursors for the synthesis of biologically active compounds - Includes information on synthetically useful transformations of N-sulfonated N-heterocycles - Covers a wide synthetic methods used for an important branch of heterocycles and their biological evaluation in detail - Features over 500 schemes to illustrate different synthetic pathways and reactions of N-sulfonated N-heterocycles

Download or read book Green Synthetic Approaches for Biologically Relevant Heterocycles written by Goutam Brahmachari and published by Elsevier. This book was released on 2021-02-26 with total page 823 pages. Available in PDF, EPUB and Kindle. Book excerpt: Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume Two: Green Catalytic Systems and Solvents reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume Two explores green catalytic systems and solvents and the techniques surrounding this approach, including metal and magnetic catalysis to organocatalysis and solid acid catalysis, cycloaddition reactions, and varied approaches using ionic liquids. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry. - Provides fully updated coverage of the field with an emphasis on sustainability - Highlights a range of different eco-friendly solvents and environmentally-friendly catalysts - Collates the experience of a global team of expert contributors

Download or read book Green Approaches in Medicinal Chemistry for Sustainable Drug Design written by Bimal Banik and published by Elsevier. This book was released on 2024-06-01 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensive experimentation and high failure rates are a well-recognised downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry, Second Edition reveals how medicinal chemistry can play a direct role in addressing this issue. After providing essential context to the growth of green chemistry in relation to drug discovery, the book goes on to identify a broad range of practical techniques and useful insights, revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process. Drawing on the knowledge of a global team of experts, Sustainable and Green Approaches in Medicinal Chemistry 2e encourages the growth of green medicinal chemistry, and supports medicinal chemists, drug discovery researchers, pharmacologists and all those in related fields across both academia and industry in integrating these approaches into their own work. This first volume of the second edition covers synthesis methods following green chemistry principles, contributing to sustainability by saving energy, using lesser toxic reagents/solvents/catalysts and environmentally benign sources including plants and agricultural materials. - Highlights the need for the adoption of sustainable and green chemistry pathways in drug development - Reveals risk factors associated with the drug development process and the ways sustainable approaches can help address these factors - Identifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability

Download or read book Advances in Heterocyclic Chemistry written by and published by Academic Press. This book was released on 1990-07-24 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Heterocyclic Chemistry

Download or read book Advances in Organometallic Chemistry written by Pedro J. Perez and published by Academic Press. This book was released on 2021-04-06 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Organometallic Chemistry, Volume 75, the latest release in this longstanding serial that is known for its comprehensive coverage of topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more provides a wide range of information, with this updated release including chapters on Two- and three-coordinate complexes featuring M-C bonds, Polymerization of terpene and terpenoids using well defined organometallic compounds, Bimetallic Frustrated Lewis Pairs, Organometallic based magnetic switches under confinement, Chemical Bonding and Dynamic Magnetism in f-Element Organometallic Sandwich Compounds, Tris-pyridyl Main Group Ligands: Design and Applications, Reactivities of N-heterocyclic carbenes at metal centers, and more. - Contains contributions from leading authorities in the field of organometallic chemistry - Covers topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more - Informs and updates readers on the latest developments in the field - Carefully edited to provide easy-to-read material

Download or read book Chlorosulfonic Acid written by Richard James William Cremlyn and published by Royal Society of Chemistry. This book was released on 2002 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since its discovery in 1854, chlorosulfonic acid has demonstrated that it is a truly versatile reagent. It is widely used as a sulfonating and chlorosulfonating agent, particularly of organic compounds, and it provides useful synthetic intermediates for many branches of industry. This book provides a detailed, up to date account of the reactions of chlorosulfonic acid with aliphatic, aromatic and heterocyclic compounds; reactions with elements and inorganic compounds are also discussed, along with the use of the reagent as a powerful acid catalyst, and halogenation and dehydrating agent. Finally, the commercial uses and manufacture of chlorosulfonic acid are reviewed. The detailed coverage in this book, coupled with the many references to recent work, will ensure that it is welcomed as a reference by synthetic chemists in, for example, the pharmaceutical, agrochemical, plastic and detergent industries. Researchers and their students in academia will also find it a valuable addition to their bookshelves.

Download or read book Green Synthetic Approaches for Biologically Relevant Heterocycles written by Goutam Brahmachari and published by Elsevier. This book was released on 2021-02-26 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume One: Advanced Synthetic Techniques reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume One explores advanced synthetic techniques, with each chapter presenting in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles that are classified on the basis of ring-size and/or the presence of heteroatoms. Techniques covered range from high pressure cycloaddition reactions and microwave irradiation to sustainable one-pot domino reactions. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry. Provides fully updated coverage of the field of greener heterocycle synthesis Includes new chapters on varied multicomponent reactions, alongside both traditional and novel approaches Presents information in an accessible style with an emphasis on sustainability

Download or read book Handbook of Heterocyclic Chemistry written by Alan R. Katritzky and published by Elsevier. This book was released on 2017-01-31 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a one-volume overall picture of the largest of the classical divisions of organic chemistry, suitable for the graduate or advanced undergraduate student, as well as for research workers, both specialists in the field and those engaged in another discipline and requiring knowledge of heterocyclic chemistry. It represents Volume 9 of Comprehensive Heterocyclic Chemistry and utilizes the general chapters which appear in the 8-volume work. The highly systematic coverage given to the subject makes this the most authoritative one-volume account of modern heterocyclic chemistry available.

Download or read book Au Catalyzed Synthesis and Functionalization of Heterocycles written by Marco Bandini and published by Springer. This book was released on 2016-07-01 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal

Download or read book Heterocyclic N Oxides written by Oleg V. Larionov and published by Springer. This book was released on 2017-07-12 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal.

Download or read book The Chemistry of Heterocycles written by Vishnu Ji Ram and published by Elsevier. This book was released on 2019-06-05 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heterocycles are ubiquitously present in nature and occupy a unique place in organic chemistry as they are part of the DNA and haemoglobin that make life possible. The Chemistry of Heterocycles covers an introduction to the topic, followed by a chapter on the nomenclature of all classes of isolated, fused and polycyclic heterocycles. The third chapter delineates the highly strained three membered N,O and S containing aromatic and non-aromatic heterocycles with one and more than one similar and dissimilar heteroatom. The four-membered heterocycles are abundantly present in various natural and synthetic products of pharmacological importance. This chapter describes the natural abundance, synthesis, chemical reactivity, structural features and their medicinal importance. This class of compounds are present as sub-structures in penicillin and cytotoxic Taxol. Lastly, a chapter on the natural abundance, synthesis, chemical reactivity and pharmacological importance of 5-membered heterocycles with N,O,S heteroatom is covered. The chemistry of heterocycles with mixed heteroatom such as, N-S, N-O, N-S etc. is also described. - Gives in-depth, clear information about various systems of nomenclature along with widely acceptable IUPAC system for naming various classes of heterocycles - Provides complete information about natural occurrences, synthesis, chemical reactivity, pharmacological importance of heterocycles and their application in material science - Highly relevant for graduate students and researchers, providing updated information about various isolated and fused N,O and,S containing heterocycles

Download or read book Heterocycles Via Cross Dehydrogenative Coupling written by Ananya Srivastava and published by . This book was released on 2019 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the developments in the synthesis and functionalization of different heterocycles based on the formation of carbon-carbon (C-C) and carbon-heteroatom (C-X) bonds using cross-dehydrogenative coupling (CDC). Consisting of 13 chapters, the book systematically describes the advances in the synthesis and functionalization of nitrogen, oxygen, and sulfur-containing heterocycles. It also discusses the various mechanistic pathways to help readers gain an in-depth understanding of the CDC reactions of heterocycles. Lastly, in order to promote green chemistry, it addresses a range of metal-free CDC reactions of heterocycles - an area that has attracted significant attention in both academic and industrial research.

Download or read book Anionic Annulations in Organic Synthesis written by Dipakranjan Mal and published by Elsevier. This book was released on 2018-10-25 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anionic Annulations in Organic Synthesis: A Versatile and Prolific Class of Ring-Forming Reactions is a comprehensive review of the main annulations for the construction of cyclic structures and their use in the total synthesis of functional molecules. The book explores in detail the Hauser, Robinson, Sammes, and Myers annulations, all of which are beneficial to constructing substrates with complex molecular structures suitable for pharmaceutical purposes. This volume begins with an in-depth introduction on the history and perspectives of annulations. It then covers different categories of annulation in each chapter, examining their application to drug synthesis for a range of different medicinal compounds. Anionic Annulations in Organic Synthesis delivers a thorough analysis of the topic and provides the tools necessary to master anionic organic chemistry. It is a valuable resource for chemists, researchers, and students seeking a complete and detailed understanding of anionic annulations. - Serves as a useful tool to both academic and industrial researchers in the field - Includes numerous examples of anionic annulations and how to apply them practically in research and industry - Features anionic annulations that are particularly effective for the synthesis of polyoxygenated polycyclic compounds

Download or read book Heterocyclic Chemistry written by Radha R. Gupta and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 649 pages. Available in PDF, EPUB and Kindle. Book excerpt: This advanced text-cum-reference book presents a comprehensive account of the syntheses, reactions, properties and applications of all the most significant classes of heterocyclic compounds. This second volume in the series is an essential tool not only for advanced undergraduates and graduates, but also for academic and industrial researchers in organic, medicinal, pharmaceutical, dye and agricultural chemistry.

Download or read book Handbook of Heterocyclic Chemistry written by Alan R. Katritzky and published by Elsevier. This book was released on 2010-08-24 with total page 1011 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heterocyclic compounds play a vital role in the metabolism of living cells. Their practical applications range from extensive clinical use to fields as diverse as agriculture, photography, biocide formulation and polymer science. Written by leading scholars and industry experts, the Handbook of Heterocyclic Chemistry is thoroughly updated with over 50% new content. It has been rewritten with a new expanded author team, who have carefully distilled essential information on the reactivity, structure and synthesis of heterocycles from the 2008 major reference work Comprehensive Heterocyclic Chemistry III. To bring the work up to date the author team have also added new synthetic examples and structures, key applications and new references from 2008-2010. Contains more than 1500 clearly drawn structures and reactions. The highly systematic coverage given to the subject makes this one of the most authoritative single-volume accounts of modern heterocyclic chemistry available and should be useful reference for those teaching a heterocyclic course. - Covers the structure, reactivity and synthesis of all heterocyclic compounds as distilled from the larger 15-volume reference work - Saves researchers time when they require important information on heterocycles--speeding them to thousands of clearly drawn chemical structures and pertinent reviews by leading experts - Features 35% new material to compliment the completely revised text

Download or read book Chiral Amine Synthesis written by Thomas C. Nugent and published by John Wiley & Sons. This book was released on 2010-01-14 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first comprehensive presentation of this hot and important topic compiles the most up-to-date methods for chiral amine synthesis. The international list of authors reads like a "Who's Who" of the subject, providing a large array of highly practical information concentrated into the useful and essential methods. Following an introductory chapter devoted to helping readers quickly determine which strategies to choose for their investigation, this handbook and ready reference focuses on the examination of methods that are reliable and simultaneously efficient for the synthesis of structurally diverse aliphatic and aromatic chiral amines. Modern methods and applications found in (pharmaceutical) industry are also covered.

Download or read book Small Ring Heterocycles Volume 42 Part 2 written by Alfred Hassner and published by John Wiley & Sons. This book was released on 2009-09-15 with total page 671 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.